-
3
-
-
0035905767
-
CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
-
(2001)
Nature
, vol.409
, pp. 349-354
-
-
Irie-Sasaki, J.1
-
4
-
-
0030725378
-
Specific inhibition of Stat3 signal transduction by PIAS3
-
(1997)
Science
, vol.278
, pp. 1803-1805
-
-
Chung, C.D.1
-
6
-
-
0029014206
-
A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
-
(1995)
EMBO J.
, vol.14
, pp. 2816-2826
-
-
Yoshimura, A.1
-
7
-
-
0033520326
-
SOCS1 is a critical inhibitor of interferon γ signaling and prevents the potentially fatal neonatal actions of this cytokine
-
(1999)
Cell
, vol.98
, pp. 597-608
-
-
Alexander, W.S.1
-
8
-
-
0033520467
-
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
-
(1999)
Cell
, vol.98
, pp. 609-616
-
-
Marine, J.C.1
-
9
-
-
13044276245
-
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 15577-15582
-
-
Naka, T.1
-
10
-
-
0035008978
-
SOCS-1/SSI-1-deficient NKT cells participate in severe hepatitis through dysregulated cross-talk inhibition of IFN-γ and IL-4 signaling in vivo
-
(2001)
Immunity
, vol.14
, pp. 535-545
-
-
Naka, T.1
-
13
-
-
0034729710
-
Gigantism in mice lacking suppressor of cytokine signalling-2
-
(2000)
Nature
, vol.405
, pp. 1069-1073
-
-
Metcalf, D.1
-
14
-
-
0033520389
-
SOCS3 is essential in the regulation of fetal liver erythropoiesis
-
(1999)
Cell
, vol.98
, pp. 617-627
-
-
Marine, J.C.1
-
17
-
-
0035975940
-
Identification of the first invertebrate interleukin JAK/STAT receptor, the Drosophila gene domeless
-
(2001)
Curr. Biol.
, vol.11
, pp. 1700-1705
-
-
Brown, S.1
-
18
-
-
0035854723
-
Suppressors of cytokine signaling-1 and -6 associate with and inhibit the insulin receptor. A potential mechanism for cytokine-mediated insulin resistance
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 25889-25893
-
-
Mooney, R.A.1
-
19
-
-
0035724763
-
Functional analysis of Asb-1 using genetic modification in mice
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6189-6197
-
-
Kile, B.T.1
-
20
-
-
0033016614
-
SWiP-1: Novel SOCS box containing WD-protein regulated by signalling centres and by Shh during development
-
(1999)
Mech. Dev.
, vol.82
, pp. 79-94
-
-
Vasiliauskas, D.1
-
21
-
-
13044263097
-
The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 2071-2076
-
-
Zhang, J.G.1
-
22
-
-
0032535364
-
The elongin BC complex interacts with the conserved SOCS-box motif present in members of the SOCS, Ras, WD-40 repeat, and ankyrin repeat families
-
(1998)
Genes Dev.
, vol.12
, pp. 3872-3881
-
-
Kamura, T.1
-
23
-
-
0027378324
-
RNA polymerase II transcription factor SIII. I. Identification, purification, and properties
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 25587-25593
-
-
Bradsher, J.N.1
-
24
-
-
0029084914
-
Elongin (SIII): A multisubunit regulator of elongation by RNA polymerase II
-
(1995)
Science
, vol.269
, pp. 1439-1443
-
-
Aso, T.1
-
25
-
-
0029147430
-
Binding of the von Hippel-Lindau tumor suppressor protein to elongin B and C
-
(1995)
Science
, vol.269
, pp. 1444-1446
-
-
Kibel, A.1
-
29
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
-
30
-
-
0033607291
-
Identification of the von Hippel-Lindau tumor-suppressor protein as part of an active E3 ubiquitin ligase complex
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 12436-12441
-
-
Iwai, K.1
-
31
-
-
0030953635
-
The von Hippel-Lindau tumor-suppressor gene product forms a stable complex with human CUL-2, a member of the Cdc53 family of proteins
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 2156-2161
-
-
Pause, A.1
-
32
-
-
0033565672
-
The von Hippel-Lindau tumor suppressor protein is a component of an E3 ubiquitin-protein ligase activity
-
(1999)
Genes Dev.
, vol.13
, pp. 1822-1833
-
-
Lisztwan, J.1
-
33
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 423-427
-
-
Ohh, M.1
-
35
-
-
0033574737
-
Structure of the VHL-elongin C-elongin B complex: Implications for VHL tumor suppressor function
-
(1999)
Science
, vol.284
, pp. 455-461
-
-
Stebbins, C.E.1
-
36
-
-
0033558088
-
Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation
-
(1999)
EMBO J.
, vol.18
, pp. 904-915
-
-
De Sepulveda, P.1
-
37
-
-
20244389693
-
The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop
-
(1999)
EMBO J.
, vol.18
, pp. 1309-1320
-
-
Yasukawa, H.1
-
38
-
-
0033555258
-
Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction
-
(1999)
EMBO J.
, vol.18
, pp. 375-385
-
-
Nicholson, S.E.1
-
40
-
-
0034724677
-
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 12848-12856
-
-
Schmitz, J.1
-
41
-
-
0001421697
-
SOCS3 mediates feedback inhibition of the leptin receptor via Tyr985
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40649-40657
-
-
Bjorbaek, C.1
-
42
-
-
0033305402
-
Mechanism of inhibition of growth hormone receptor signaling by suppressor of cytokine signaling proteins
-
(1999)
Mol. Endocrinol.
, vol.13
, pp. 1832-1843
-
-
Hansen, J.A.1
-
43
-
-
0034640526
-
Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14005-14008
-
-
De Sepulveda, P.1
-
44
-
-
0035864739
-
The TEL-Jak2 oncoprotein induces Socs1 expression and altered cytokine response in Ba/F3 cells
-
(2001)
Oncogene
, vol.20
, pp. 849-858
-
-
Monni, R.1
-
45
-
-
0035036625
-
Socs-1 inhibits TEK-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 3547-3557
-
-
Frantsve, J.1
-
46
-
-
0036233985
-
Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1
-
in press
-
Mol. Cell. Biol.
-
-
Ungureanu, D.1
-
48
-
-
0032561322
-
Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 28185-28190
-
-
Verdier, F.1
-
49
-
-
0028826589
-
Cellular proteins that bind the von Hippel-Lindau disease gene product: Mapping of binding domains and the effect of missense mutations
-
(1995)
Cancer Res.
, vol.55
, pp. 4544-4548
-
-
Kishida, T.1
-
52
-
-
0033521072
-
Setting the standards: Quality control in the secretory pathway
-
(1999)
Science
, vol.286
, pp. 1882-1888
-
-
Ellgaard, L.1
-
53
-
-
0035651380
-
Drosophila Neuralized is a ubiquitin ligase that promotes the internalization and degradation of Delta
-
(2001)
Dev. Cell
, vol.1
, pp. 783-794
-
-
Lai, E.C.1
-
54
-
-
0035650895
-
Xenopus Neuralized is a ubiquitin ligase that interacts with XDelta1 and regulates Notch signaling
-
(2001)
Dev. Cell
, vol.1
, pp. 795-806
-
-
Deblandre, G.A.1
-
55
-
-
14444271600
-
Identification of a human homolog of the Drosophila Neuralized gene within the 10q25.1 malignant astrocytoma deletion region
-
(1998)
Oncogene
, vol.16
, pp. 1009-1019
-
-
Nakamura, H.1
-
57
-
-
0031831274
-
Combinatorial control in ubiquitin-dependent proteolysis: Don't Skp the F-box hypothesis
-
(1998)
Trends Genet.
, vol.14
, pp. 236-243
-
-
Patton, E.E.1
-
58
-
-
0033176887
-
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27
-
(1999)
Nat. Cell Biol.
, vol.1
, pp. 193-199
-
-
Carrano, A.C.1
-
59
-
-
0034676443
-
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex
-
(2000)
Nature
, vol.408
, pp. 381-386
-
-
Schulman, B.A.1
|