Hypermethylation associated with inactivation of the SOCS-1 gene, a JAK/STAT inhibitor, in human hepatoblastomas

Journal of Human Genetics

Volumn 48, Issue 2, 2003, Pages 65-69

  Nagai, Hisaki ^a   Naka, Tetsuji ^b   Terada, Yoshie ^a   Komazaki, Toshiaki ^a   Yabe, Aya ^a   Jin, Enjing ^a   Kawanami, Oichi ^a   Kishimoto, Tadamitsu ^b   Konishi, Noboru ^c   Nakamura, Mitsutoshi ^c   Kobayashi, Yasuhito ^d   Emi, Mitsuru ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

^b OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c NARA MEDICAL UNIVERSITY   (Japan)

^d SAITAMA CANCER CENTER   (Japan)

Author keywords

Hepatoblastoma; Hepatocellular carcinoma; JAK STAT; Methylation; SSI 1 SOCS 1 JAB

Indexed keywords

GENE PRODUCT; JAK BINDING PROTEIN; JANUS KINASE; JANUS KINASE INHIBITOR; STAT PROTEIN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CHILDHOOD CANCER; CLINICAL ARTICLE; CPG ISLAND; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; GENE INACTIVATION; GENE SILENCING; GENETIC CODE; HEPATOBLASTOMA; HUMAN; HUMAN TISSUE; HYPERMETHYLATION; INFANT; INHIBITION KINETICS; LIVER CELL CARCINOMA; LIVER TUMOR; MALE; METHYLATION; NUCLEOTIDE SEQUENCE; PROTEIN BINDING; SIGNAL TRANSDUCTION; SOCS1 GENE;

ADOLESCENT; CARRIER PROTEINS; CHILD; DNA METHYLATION; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION; GENE SILENCING; GENES, TUMOR SUPPRESSOR; HEPATOBLASTOMA; HUMANS; INFANT; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER NEOPLASMS; MALE; REPRESSOR PROTEINS; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

JANUS;

EID: 0037227602     PISSN: 14345161     EISSN: None     Source Type: Journal    
DOI: 10.1007/s100380300008     Document Type: Article

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