Identification of an acquired JAK2 mutation in polycythemia vera

Journal of Biological Chemistry

Volumn 280, Issue 24, 2005, Pages 22788-22792

  Zhao, Runxiang ^a   Xing, Shu ^a,b   Li, Zhe ^a,b   Fu, Xueqi ^b   Li, Qingshan ^b   Krantz, Sanford B ^a   Zhao, Zhizhuang Joe ^a,b,c  

^a VANDERBILT UNIVERSITY   (United States)

^b JILIN UNIVERSITY   (China)

^c 777 Preston Research Bldg ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLONING; DISEASE CONTROL; DNA; ENZYMES; MOLECULAR DYNAMICS; SENSITIVITY ANALYSIS;

HEMATOLOGICAL DISORDERS; HETEROZYGOSITY; POLYCYTHEMIA VERA (PV); PSEUDOKINASE;

MUTAGENESIS;

COMPLEMENTARY DNA; CYTOKINE; ERYTHROPOIETIN RECEPTOR; GROWTH FACTOR; JANUS KINASE 2; PHENYLALANINE; PHOSPHATASE; PROTEIN TYROSINE KINASE; VALINE;

AMINO ACID SUBSTITUTION; ARTICLE; ENZYME ACTIVITY; GENE OVEREXPRESSION; HEMATOPOIETIC STEM CELL; HETEROZYGOSITY; HUMAN; HUMAN CELL; MUTATION; POINT MUTATION; POLYCYTHEMIA VERA; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CYTOKINES; DNA MUTATIONAL ANALYSIS; DNA, COMPLEMENTARY; ERYTHROPOIETIN; HELA CELLS; HETEROZYGOTE; HUMANS; IMMUNOBLOTTING; JANUS KINASE 2; MOLECULAR SEQUENCE DATA; MUTATION; PHENYLALANINE; POINT MUTATION; POLYCYTHEMIA VERA; POLYMERASE CHAIN REACTION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; RECEPTORS, ERYTHROPOIETIN; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; TRANSFECTION; TYROSINE; VALINE;

EID: 20744460045     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.C500138200     Document Type: Article

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