메뉴 건너뛰기




Volumn 95, Issue 6, 2000, Pages 2076-2083

Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells

Author keywords

[No Author keywords available]

Indexed keywords

HYBRID PROTEIN; JANUS KINASE; STAT5 PROTEIN;

EID: 0034653478     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v95.6.2076     Document Type: Article
Times cited : (118)

References (50)
  • 2
    • 0030840464 scopus 로고    scopus 로고
    • STATs and gene regulation
    • Darnell JE Jr. STATs and gene regulation. Science. 1997;277:1630-1635.
    • (1997) Science , vol.277 , pp. 1630-1635
    • Darnell J.E., Jr.1
  • 3
    • 0030804219 scopus 로고    scopus 로고
    • The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs)
    • Pellegrini S, Dusanter-Fourt I. The structure, regulation and function of the Janus kinases (JAKs) and the signal transducers and activators of transcription (STATs). Eur J Biochem. 1997; 248:615-633.
    • (1997) Eur J Biochem , vol.248 , pp. 615-633
    • Pellegrini, S.1    Dusanter-Fourt, I.2
  • 4
    • 0031800697 scopus 로고    scopus 로고
    • Activation of STAT transcription factors in oncogenic tyrosine kinase signaling
    • Garcia R, Jove R. Activation of STAT transcription factors in oncogenic tyrosine kinase signaling. J Biomed Sci. 1998;5:79-85.
    • (1998) J Biomed Sci , vol.5 , pp. 79-85
    • Garcia, R.1    Jove, R.2
  • 6
    • 0031953831 scopus 로고    scopus 로고
    • Stat3 activation by Src induces specific gene regulation and is required for cell transformation
    • Turkson J, Bowman T, Garcia R, Caldenhoven E, De Groot RP, Jove R. Stat3 activation by Src induces specific gene regulation and is required for cell transformation. Mol Cell Biol. 1998;18:2545-2552.
    • (1998) Mol Cell Biol , vol.18 , pp. 2545-2552
    • Turkson, J.1    Bowman, T.2    Garcia, R.3    Caldenhoven, E.4    De Groot, R.P.5    Jove, R.6
  • 7
    • 15444339209 scopus 로고    scopus 로고
    • A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
    • Lacronique V, Boureux A, Valle VD, et al. A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science. 1997;278:1309-1312.
    • (1997) Science , vol.278 , pp. 1309-1312
    • Lacronique, V.1    Boureux, A.2    Valle, V.D.3
  • 8
    • 0030852328 scopus 로고    scopus 로고
    • Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9; 12) in a lymphoid and t(9;15:12) in a myeloid leukemia
    • Peeters P, Raynaud SD, Cools J, et al. Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9; 12) in a lymphoid and t(9;15:12) in a myeloid leukemia. Blood. 1997;90:2535-2540.
    • (1997) Blood , vol.90 , pp. 2535-2540
    • Peeters, P.1    Raynaud, S.D.2    Cools, J.3
  • 9
    • 0029898682 scopus 로고    scopus 로고
    • Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia
    • Golub TR, Goga A, Barker GF, et al. Oligomerization of the ABL tyrosine kinase by the Ets protein TEL in human leukemia. Mol Cell Biol. 1996;16: 4107-4116.
    • (1996) Mol Cell Biol , vol.16 , pp. 4107-4116
    • Golub, T.R.1    Goga, A.2    Barker, G.F.3
  • 10
    • 17144463437 scopus 로고    scopus 로고
    • A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein
    • Jousset C, Carron C, Boureux A, et al. A domain of TEL conserved in a subset of ETS proteins defines a specific oligomerization interface essential to the mitogenic properties of the TEL-PDGFR beta oncoprotein. EMBO J. 1997;16:69-82.
    • (1997) EMBO J , vol.16 , pp. 69-82
    • Jousset, C.1    Carron, C.2    Boureux, A.3
  • 11
    • 0029966854 scopus 로고    scopus 로고
    • The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways
    • Carroll M, Tomasson MH, Barker GF, Golub TR, Gilliland DG. The TEL/platelet-derived growth factor beta receptor (PDGF beta R) fusion in chronic myelomonocytic leukemia is a transforming protein that self-associates and activates PDGF beta R kinase-dependent signaling pathways. Proc Natl Acad Sci U S A. 1996;93:14,845-14,850.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 14845-14850
    • Carroll, M.1    Tomasson, M.H.2    Barker, G.F.3    Golub, T.R.4    Gilliland, D.G.5
  • 12
    • 0033595087 scopus 로고    scopus 로고
    • IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line
    • Dumon S, Santos SC, Debierre-Grockiego F, et al. IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line [In Process Citation]. Oncogene. 1999;18: 4191-4199.
    • (1999) Oncogene , vol.18 , pp. 4191-4199
    • Dumon, S.1    Santos, S.C.2    Debierre-Grockiego, F.3
  • 13
    • 0029010473 scopus 로고
    • Thrombopoietin activates a STAT5-like factor in hematopoietic cells
    • Pallard C, Gouilleux F, Benit L, et al. Thrombopoietin activates a STAT5-like factor in hematopoietic cells. EMBO J. 1995;14:2847-2856.
    • (1995) EMBO J , vol.14 , pp. 2847-2856
    • Pallard, C.1    Gouilleux, F.2    Benit, L.3
  • 14
    • 17944383969 scopus 로고    scopus 로고
    • A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dinners: A distinct biochemical difference between STAT5A and STAT5B
    • Verdier F, Rabionet R, Gouilleux F, et al. A sequence of the CIS gene promoter interacts preferentially with two associated STAT5A dinners: a distinct biochemical difference between STAT5A and STAT5B. Mol Cell Biol. 1998;18:5852-5860.
    • (1998) Mol Cell Biol , vol.18 , pp. 5852-5860
    • Verdier, F.1    Rabionet, R.2    Gouilleux, F.3
  • 15
    • 8044224661 scopus 로고    scopus 로고
    • The TEL gene products: Nuclear phosphoproteins with DNA binding properties
    • Poirel H, Oury C, Carron C, et al. The TEL gene products: nuclear phosphoproteins with DNA binding properties. Oncogene. 1997;14:349-357.
    • (1997) Oncogene , vol.14 , pp. 349-357
    • Poirel, H.1    Oury, C.2    Carron, C.3
  • 16
    • 0027993605 scopus 로고
    • Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription
    • Gouilleux F, Wakao H, Mundt M, Groner B. Prolactin induces phosphorylation of Tyr694 of Stat5 (MGF), a prerequisite for DNA binding and induction of transcription. EMBO J. 1994;13:4361-4369.
    • (1994) EMBO J , vol.13 , pp. 4361-4369
    • Gouilleux, F.1    Wakao, H.2    Mundt, M.3    Groner, B.4
  • 17
    • 0029967128 scopus 로고    scopus 로고
    • Interleukin 3 activates not only JAK2 and STAT5, but also Tyk2, STAT1, and STAT3
    • Nagata Y, Todokoro K. Interleukin 3 activates not only JAK2 and STAT5, but also Tyk2, STAT1, and STAT3. Biochem Biophys Res Commun. 1996; 221:785-789.
    • (1996) Biochem Biophys Res Commun , vol.221 , pp. 785-789
    • Nagata, Y.1    Todokoro, K.2
  • 18
    • 0025639009 scopus 로고
    • The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter
    • Wagner BJ, Hayes TE, Hoban CJ, Cochran BH. The SIF binding element confers sis/PDGF inducibility onto the c-fos promoter. EMBO J. 1990;9: 4477-4484.
    • (1990) EMBO J , vol.9 , pp. 4477-4484
    • Wagner, B.J.1    Hayes, T.E.2    Hoban, C.J.3    Cochran, B.H.4
  • 19
    • 0027489710 scopus 로고
    • Receptors for granulocyte-macrophage colony-stimulating factor, interlsukin-3, and interleukin-5
    • Miyajima A, Mui AL, Ogorochi T, Sakamaki K. Receptors for granulocyte-macrophage colony-stimulating factor, interlsukin-3, and interleukin-5. Blood. 1993;82:1960-2974.
    • (1993) Blood , vol.82 , pp. 1960-2974
    • Miyajima, A.1    Mui, A.L.2    Ogorochi, T.3    Sakamaki, K.4
  • 20
    • 17044444647 scopus 로고    scopus 로고
    • STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction
    • Takeshita T, Arita T, Higuchi M, et al. STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc induction. Immunity. 1997; 6:449-457.
    • (1997) Immunity , vol.6 , pp. 449-457
    • Takeshita, T.1    Arita, T.2    Higuchi, M.3
  • 21
    • 0032030688 scopus 로고    scopus 로고
    • Tec and Jak2 kinases cooperate to mediate cytokine-driven activation of c-fos transcription
    • Yamashita Y, Watanabe S, Miyazato A, et al. Tec and Jak2 kinases cooperate to mediate cytokine-driven activation of c-fos transcription. Blood. 1998;91:1496-1507.
    • (1998) Blood , vol.91 , pp. 1496-1507
    • Yamashita, Y.1    Watanabe, S.2    Miyazato, A.3
  • 23
    • 0029014206 scopus 로고
    • A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors
    • Yoshimura A, Ohkubo T, Kiguchi T, et al. A novel cytokine-inducible gene CIS encodes an SH2-containing protein that binds to tyrosine-phosphorylated interleukin 3 and erythropoietin receptors. EMBO J. 1995;14:2816-2826.
    • (1995) EMBO J , vol.14 , pp. 2816-2826
    • Yoshimura, A.1    Ohkubo, T.2    Kiguchi, T.3
  • 24
    • 0029870042 scopus 로고    scopus 로고
    • Mouse oncostatin M: An immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway
    • Yoshimura A, Ichihara M, Kinjyo I, et al. Mouse oncostatin M: an immediate early gene induced by multiple cytokines through the JAK-STAT5 pathway. EMBO J. 1996;15:1055-1063.
    • (1996) EMBO J , vol.15 , pp. 1055-1063
    • Yoshimura, A.1    Ichihara, M.2    Kinjyo, I.3
  • 25
    • 0029892399 scopus 로고    scopus 로고
    • Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: Role of Stat5 in proliferation
    • Mui AL, Wakao H, Kinoshita T, Kitamura T, Miyajima A. Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation. EMBO J. 1996;15: 2425-2433.
    • (1996) EMBO J , vol.15 , pp. 2425-2433
    • Mui, A.L.1    Wakao, H.2    Kinoshita, T.3    Kitamura, T.4    Miyajima, A.5
  • 26
    • 0030956715 scopus 로고    scopus 로고
    • CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation
    • Matsumoto A, Masuhara M, Mitsui K, et la. CIS, a cytokine inducible SH2 protein, is a target of the JAK-STAT5 pathway and modulates STAT5 activation. Blood. 1997;89:3148-3154.
    • (1997) Blood , vol.89 , pp. 3148-3154
    • Matsumoto, A.1    Masuhara, M.2    Mitsui, K.3
  • 27
    • 10144258658 scopus 로고    scopus 로고
    • Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype
    • Moriggl R, Gouilleux-Gruart V, Jahne R, et al. Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype. Mol Cell Biol. 1996;16:5691-5700.
    • (1996) Mol Cell Biol , vol.16 , pp. 5691-5700
    • Moriggl, R.1    Gouilleux-Gruart, V.2    Jahne, R.3
  • 28
    • 0032530972 scopus 로고    scopus 로고
    • Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
    • Schwaller J, Frantsve J, Aster J, et al. Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO J. 1998;17:5321-5333.
    • (1998) EMBO J , vol.17 , pp. 5321-5333
    • Schwaller, J.1    Frantsve, J.2    Aster, J.3
  • 29
    • 0030766684 scopus 로고    scopus 로고
    • Signal transduction pathways involved in BCR-ABL transformation
    • Sawyers CL. Signal transduction pathways involved in BCR-ABL transformation. Baillieres Clin Haematol. 1997;10:223-231.
    • (1997) Baillieres Clin Haematol , vol.10 , pp. 223-231
    • Sawyers, C.L.1
  • 30
    • 0028835347 scopus 로고
    • Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction
    • Velazquez L, Mogensen KE, Barbieri G, Fellous M, Uze G, Pellegrini S. Distinct domains of the protein tyrosine kinase tyk2 required for binding of interferon-alpha/beta and for signal transduction. J Biol Chem. 1995;270:3327-3334.
    • (1995) J Biol Chem , vol.270 , pp. 3327-3334
    • Velazquez, L.1    Mogensen, K.E.2    Barbieri, G.3    Fellous, M.4    Uze, G.5    Pellegrini, S.6
  • 31
    • 0031017533 scopus 로고    scopus 로고
    • Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways
    • Luo H, Rose P, Barber D, et al. Mutation in the Jak kinase JH2 domain hyperactivates Drosophila and mammalian Jak-Stat pathways. Mol Cell Biol. 1997;17:1562-1571.
    • (1997) Mol Cell Biol , vol.17 , pp. 1562-1571
    • Luo, H.1    Rose, P.2    Barber, D.3
  • 32
    • 0344517071 scopus 로고    scopus 로고
    • Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling
    • Ho JM, Beattie BK, Squire JA, Frank DA, Barber DL. Fusion of the ets transcription factor TEL to Jak2 results in constitutive Jak-Stat signaling. Blood. 1999;93:4354-4364.
    • (1999) Blood , vol.93 , pp. 4354-4364
    • Ho, J.M.1    Beattie, B.K.2    Squire, J.A.3    Frank, D.A.4    Barber, D.L.5
  • 33
    • 0029011115 scopus 로고
    • The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain
    • Zhao Y, Wagner F, Frank SJ, Kraft AS. The amino-terminal portion of the JAK2 protein kinase is necessary for binding and phosphorylation of the granulocyte-macrophage colony-stimulating factor receptor beta c chain. J Biol Chem. 1995; 270:13,814-13,818.
    • (1995) J Biol Chem , vol.270 , pp. 13814-13818
    • Zhao, Y.1    Wagner, F.2    Frank, S.J.3    Kraft, A.S.4
  • 34
    • 0031792831 scopus 로고    scopus 로고
    • Activation and functional analysis of Janus kinase 2 in BA/F3 cells using the Coumermycin/Gyrase B system
    • Mohi MG, Arai K, Watanabe S. Activation and functional analysis of Janus kinase 2 in BA/F3 cells using the Coumermycin/Gyrase B system. Mol Biol Cell. 1998;9:3299-3308.
    • (1998) Mol Biol Cell , vol.9 , pp. 3299-3308
    • Mohi, M.G.1    Arai, K.2    Watanabe, S.3
  • 35
    • 0029024882 scopus 로고
    • Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor
    • Frank SJ, Yi W, Zhao Y, et al. Regions of the JAK2 tyrosine kinase required for coupling to the growth hormone receptor. J Biol Chem. 1995; 270:14,776-14,785.
    • (1995) J Biol Chem , vol.270 , pp. 14776-14785
    • Frank, S.J.1    Yi, W.2    Zhao, Y.3
  • 36
    • 8044231313 scopus 로고    scopus 로고
    • An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT
    • Fujitani Y, Hibi M, Fukada T, et al. An alternative pathway for STAT activation that is mediated by the direct interaction between JAK and STAT. Oncogene. 1997;14:751-761.
    • (1997) Oncogene , vol.14 , pp. 751-761
    • Fujitani, Y.1    Hibi, M.2    Fukada, T.3
  • 38
    • 0029869176 scopus 로고    scopus 로고
    • The SH2 domains of stat1 and stat2 mediate multiple interactions in the transduction of IFN-alpha signals
    • Gupta S, Yan H, Wong LH, Ralph S, Krolewski J, Schindler C. The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signals. EMBO J. 1996;15:1075-1084.
    • (1996) EMBO J , vol.15 , pp. 1075-1084
    • Gupta, S.1    Yan, H.2    Wong, L.H.3    Ralph, S.4    Krolewski J, S.C.5
  • 39
    • 0029680564 scopus 로고    scopus 로고
    • P210 Bcr-Abl interacts with the interleukin 3 receptor beta(c) subunit and constitutively induces its tyrosine phosphorylation
    • Wilson-Rawls J, Xie S, Liu J, Laneuville P, Arlinghaus RB. P210 Bcr-Abl interacts with the interleukin 3 receptor beta(c) subunit and constitutively induces its tyrosine phosphorylation. Cancer Res. 1996;56:3426-3430.
    • (1996) Cancer Res , vol.56 , pp. 3426-3430
    • Wilson-Rawls, J.1    Xie, S.2    Liu, J.3    Laneuville, P.4    Arlinghaus, R.B.5
  • 40
    • 0000506439 scopus 로고    scopus 로고
    • P210 and P190(BCR/ ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members
    • Ilaria RL Jr, Van Etten RA. P210 and P190(BCR/ ABL) induce the tyrosine phosphorylation and DNA binding activity of multiple specific STAT family members. J Biol Chem. 1996;271:31,704-31,710.
    • (1996) J Biol Chem , vol.271 , pp. 31704-31710
    • Ilaria R.L., Jr.1    Van Etten, R.A.2
  • 41
    • 0026788001 scopus 로고
    • Dominant negative MYC blocks transformation by ABL oncogenes
    • Sawyers CL, Callahan W, Witte ON. Dominant negative MYC blocks transformation by ABL oncogenes. Cell. 1992;70:901-910.
    • (1992) Cell , vol.70 , pp. 901-910
    • Sawyers, C.L.1    Callahan, W.2    Witte, O.N.3
  • 42
    • 0031931409 scopus 로고    scopus 로고
    • Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor
    • Itoh T, Liu R, Yokota T, Arai KI, Watanabe S. Definition of the role of tyrosine residues of the common beta subunit regulating multiple signaling pathways of granulocyte-macrophage colony-stimulating factor receptor. Mol Cell Biol. 1998;18: 742-752.
    • (1998) Mol Cell Biol , vol.18 , pp. 742-752
    • Itoh, T.1    Liu, R.2    Yokota, T.3    Arai, K.I.4    Watanabe, S.5
  • 43
    • 0033534384 scopus 로고    scopus 로고
    • STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation
    • Welte T, Leitenberg D, Dittel BN, et la. STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation. Science. 1999; 283:222-225.
    • (1999) Science , vol.283 , pp. 222-225
    • Welte, T.1    Leitenberg, D.2    Dittel, B.N.3
  • 44
    • 0033106168 scopus 로고    scopus 로고
    • Transcriptional regulation of the cyclin D1 promoter by STAT5: Its involvement in cytokine-dependent growth of hematopoietic cells
    • Matsumura I, Kitamura T, Wakao H, et al. Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells. EMBO J. 1999;18: 1367-1377.
    • (1999) EMBO J , vol.18 , pp. 1367-1377
    • Matsumura, I.1    Kitamura, T.2    Wakao, H.3
  • 45
    • 0033082138 scopus 로고    scopus 로고
    • Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells
    • Moriggl R, Topham DJ, Teglund S, et al. Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells. Immunity. 1999;10:249-259.
    • (1999) Immunity , vol.10 , pp. 249-259
    • Moriggl, R.1    Topham, D.J.2    Teglund, S.3
  • 46
    • 18844480398 scopus 로고    scopus 로고
    • Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21 (WAF1/ Cip1) by STAT5
    • Matsumura I, Ishikawa J, Nakajima K, et al. Thrombopoietin-induced differentiation of a human megakaryoblastic leukemia cell line, CMK, involves transcriptional activation of p21 (WAF1/ Cip1) by STAT5. Mol Cell Biol. 1997;17:2933-2943.
    • (1997) Mol Cell Biol , vol.17 , pp. 2933-2943
    • Matsumura, I.1    Ishikawa, J.2    Nakajima, K.3
  • 47
    • 0000943469 scopus 로고    scopus 로고
    • Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses
    • Teglund S, McKay C, Schuetz E, et al. Stat5a and Stat5b proteins have essential and nonessential, or redundant, roles in cytokine responses. Cell. 1998;93:841-850.
    • (1998) Cell , vol.93 , pp. 841-850
    • Teglund, S.1    McKay, C.2    Schuetz, E.3
  • 48
    • 0032055611 scopus 로고    scopus 로고
    • Regulation of cell growth by IL-2: Role of STAT5 in protection from apoptosis but not in cell cycle progression
    • Zamorano J, Wang HY, Wang R, Shi Y, Longmore GD, Keegan AD. Regulation of cell growth by IL-2: role of STAT5 in protection from apoptosis but not in cell cycle progression. J Immunol. 1998;160:3502-3512.
    • (1998) J Immunol , vol.160 , pp. 3502-3512
    • Zamorano, J.1    Wang, H.Y.2    Wang, R.3    Shi, Y.4    Longmore, G.D.5    Keegan, A.D.6
  • 49
    • 0033597715 scopus 로고    scopus 로고
    • Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: A direct role for Stat5 in Bcl-X(L) induction
    • Socolovsky M, Fallon AE, Wang S, Brugnara C, Lodish HF. Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction. Cell. 1999;98:181-191.
    • (1999) Cell , vol.98 , pp. 181-191
    • Socolovsky, M.1    Fallon, A.E.2    Wang, S.3    Brugnara, C.4    Lodish, H.F.5
  • 50
    • 0031836964 scopus 로고    scopus 로고
    • Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation
    • Onishi M, Nosaka T, Misawa K, et al. Identification and characterization of a constitutively active STAT5 mutant that promotes cell proliferation. Mol Cell Biol. 1998;18:3871-3879.
    • (1998) Mol Cell Biol , vol.18 , pp. 3871-3879
    • Onishi, M.1    Nosaka, T.2    Misawa, K.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.