-
1
-
-
0036595049
-
Suppressors of cytokine signalling (SOCS) in the immune system
-
Alexander, W.S. (2002) Suppressors of cytokine signalling (SOCS) in the immune system. Nature Reviews in Immunology, 2, 410-416.
-
(2002)
Nature Reviews in Immunology
, vol.2
, pp. 410-416
-
-
Alexander, W.S.1
-
2
-
-
0033520326
-
SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine
-
Alexander, W.S., Starr, R., Fenner, J.E., Scott, C.L., Handman, E., Sprigg, N.S., Corbin, J.E., Cornish, A.L., Darwiche, R., Owczarek, C.M., Kay, T.W., Nicola, N.A., Hertzog, P.J., Metcalf, D. & Hilton, D.J. (1999) SOCS1 is a critical inhibitor of interferon gamma signaling and prevents the potentially fatal neonatal actions of this cytokine. Cell, 98, 597-608.
-
(1999)
Cell
, vol.98
, pp. 597-608
-
-
Alexander, W.S.1
Starr, R.2
Fenner, J.E.3
Scott, C.L.4
Handman, E.5
Sprigg, N.S.6
Corbin, J.E.7
Cornish, A.L.8
Darwiche, R.9
Owczarek, C.M.10
Kay, T.W.11
Nicola, N.A.12
Hertzog, P.J.13
Metcalf, D.14
Hilton, D.J.15
-
3
-
-
0034744639
-
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
-
Baylin, S.B., Esteller, M., Rountree, M.R., Bachman, K.E., Schuebel, K. & Herman, J.G. (2001) Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer. Human Molecular Genetics, 10, 687-692.
-
(2001)
Human Molecular Genetics
, vol.10
, pp. 687-692
-
-
Baylin, S.B.1
Esteller, M.2
Rountree, M.R.3
Bachman, K.E.4
Schuebel, K.5
Herman, J.G.6
-
4
-
-
0037229094
-
Mutations in SBDS are associated with Shwachman-Diamond syndrome
-
Boocock, G.R., Morrison, J.A., Popovic, M., Richards, N., Ellis, L., Durie, P.R. & Rommens, J.M. (2003) Mutations in SBDS are associated with Shwachman-Diamond syndrome. Nature Genetics, 33, 97-101.
-
(2003)
Nature Genetics
, vol.33
, pp. 97-101
-
-
Boocock, G.R.1
Morrison, J.A.2
Popovic, M.3
Richards, N.4
Ellis, L.5
Durie, P.R.6
Rommens, J.M.7
-
5
-
-
0038546657
-
SOCS1 methylation in patients with newly diagnosed acute myeloid leukemia
-
Chen, C.Y., Tsay, W., Tang, J.L., Shen, H.L., Lin, S.W., Huang, S.Y., Yao, M., Chen, Y.C., Shen, M.C., Wang, C.H. & Tien, H.F. (2003) SOCS1 methylation in patients with newly diagnosed acute myeloid leukemia. Genes Chromosomes Cancer, 37, 300-305.
-
(2003)
Genes Chromosomes Cancer
, vol.37
, pp. 300-305
-
-
Chen, C.Y.1
Tsay, W.2
Tang, J.L.3
Shen, H.L.4
Lin, S.W.5
Huang, S.Y.6
Yao, M.7
Chen, Y.C.8
Shen, M.C.9
Wang, C.H.10
Tien, H.F.11
-
6
-
-
0037938816
-
SOCS3 negatively regulates IL-6 signaling in vivo
-
Croker, B.A., Krebs, D.L., Zhang, J.G., Wormald, S., Willson, T.A., Stanley, E.G., Robb, L., Greenhalgh, C.J., Forster, I., Clausen, B.E., Nicola, N.A., Metcalf, D., Hilton, D.J., Roberts, A.W. & Alexander, W.S. (2003) SOCS3 negatively regulates IL-6 signaling in vivo. Natural Immunology, 4, 540-545.
-
(2003)
Natural Immunology
, vol.4
, pp. 540-545
-
-
Croker, B.A.1
Krebs, D.L.2
Zhang, J.G.3
Wormald, S.4
Willson, T.A.5
Stanley, E.G.6
Robb, L.7
Greenhalgh, C.J.8
Forster, I.9
Clausen, B.E.10
Nicola, N.A.11
Metcalf, D.12
Hilton, D.J.13
Roberts, A.W.14
Alexander, W.S.15
-
7
-
-
0033558088
-
Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation
-
De Sepulveda, P., Okkenhaug, K., Rose, J.L., Hawley, R.G., Dubreuil, P. & Rottapel, R. (1999) Socs1 binds to multiple signalling proteins and suppresses steel factor-dependent proliferation. EMBO Journal, 18, 904-915.
-
(1999)
EMBO Journal
, vol.18
, pp. 904-915
-
-
De Sepulveda, P.1
Okkenhaug, K.2
Rose, J.L.3
Hawley, R.G.4
Dubreuil, P.5
Rottapel, R.6
-
8
-
-
0041525763
-
SOCS-1 gene methylation is frequent but does not appear to have prognostic value in patients with multiple myeloma
-
Depil, S., Saudemont, A. & Quesnel, B. (2003) SOCS-1 gene methylation is frequent but does not appear to have prognostic value in patients with multiple myeloma. Leukemia, 17, 1678-1679.
-
(2003)
Leukemia
, vol.17
, pp. 1678-1679
-
-
Depil, S.1
Saudemont, A.2
Quesnel, B.3
-
9
-
-
0028328265
-
Identification of a nonsense mutation in the granulocyte-colony- stimulating factor receptor in severe congenital neutropenia
-
Dong, F., Hoefsloot, L.H., Schelen, A.M., Broeders, C.A., Meijer, Y., Veerman, A.J., Touw, I.P. & Lowenberg, B. (1994) Identification of a nonsense mutation in the granulocyte-colony-stimulating factor receptor in severe congenital neutropenia. Proceedings of the Natational Academy of Sciences of the United States of America, 91, 4480-4484.
-
(1994)
Proceedings of the Natational Academy of Sciences of the United States of America
, vol.91
, pp. 4480-4484
-
-
Dong, F.1
Hoefsloot, L.H.2
Schelen, A.M.3
Broeders, C.A.4
Meijer, Y.5
Veerman, A.J.6
Touw, I.P.7
Lowenberg, B.8
-
10
-
-
0032490874
-
Demethylation of the progesterone receptor CpG island is not required for progesterone receptor gene expression
-
Ferguson, A.T., Lapidus, R.G. & Davidson, N.E. (1998) Demethylation of the progesterone receptor CpG island is not required for progesterone receptor gene expression. Oncogene, 17, 577-583.
-
(1998)
Oncogene
, vol.17
, pp. 577-583
-
-
Ferguson, A.T.1
Lapidus, R.G.2
Davidson, N.E.3
-
11
-
-
0344440953
-
Regulation of cytokine signaling by SOCS family molecules
-
Fujimoto, M. & Naka, T. (2003) Regulation of cytokine signaling by SOCS family molecules. Trends in Immunology, 24, 659-666.
-
(2003)
Trends in Immunology
, vol.24
, pp. 659-666
-
-
Fujimoto, M.1
Naka, T.2
-
12
-
-
0036849109
-
A regulatory role for suppressor of cytokine signaling-1 in T(h) polarization in vivo
-
Fujimoto, M., Tsutsui, H., Yumikura-Futatsugi, S., Ueda, H., Xingshou, O., Abe, T., Kawase, I., Nakanishi, K., Kishimoto, T. & Naka, T. (2002) A regulatory role for suppressor of cytokine signaling-1 in T(h) polarization in vivo. International Immunology, 14, 1343-1350.
-
(2002)
International Immunology
, vol.14
, pp. 1343-1350
-
-
Fujimoto, M.1
Tsutsui, H.2
Yumikura-Futatsugi, S.3
Ueda, H.4
Xingshou, O.5
Abe, T.6
Kawase, I.7
Nakanishi, K.8
Kishimoto, T.9
Naka, T.10
-
13
-
-
10744227089
-
Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases
-
Fujimoto, M., Tsutsui, H., Xinshou, O., Tokumoto, M., Watanabe, D., Shima, Y., Yoshimoto, T., Hirakata, H., Kawase, I., Nakanishi, K., Kishimoto, T. & Naka, T. (2004) Inadequate induction of suppressor of cytokine signaling-1 causes systemic autoimmune diseases. International Immunology, 16, 303-314.
-
(2004)
International Immunology
, vol.16
, pp. 303-314
-
-
Fujimoto, M.1
Tsutsui, H.2
Xinshou, O.3
Tokumoto, M.4
Watanabe, D.5
Shima, Y.6
Yoshimoto, T.7
Hirakata, H.8
Kawase, I.9
Nakanishi, K.10
Kishimoto, T.11
Naka, T.12
-
14
-
-
0042575343
-
Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms
-
Fukushima, N., Sato, N., Sahin, F., Su, G.H., Hruban, R.H. & Goggins, M. (2003) Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms. British Journal of Cancer, 89, 338-343.
-
(2003)
British Journal of Cancer
, vol.89
, pp. 338-343
-
-
Fukushima, N.1
Sato, N.2
Sahin, F.3
Su, G.H.4
Hruban, R.H.5
Goggins, M.6
-
15
-
-
0038784365
-
SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma
-
Galm, O., Yoshikawa, H., Esteller, M., Osieka, R. & Herman, J.G. (2003) SOCS-1, a negative regulator of cytokine signaling, is frequently silenced by methylation in multiple myeloma. Blood, 101, 2784-2788.
-
(2003)
Blood
, vol.101
, pp. 2784-2788
-
-
Galm, O.1
Yoshikawa, H.2
Esteller, M.3
Osieka, R.4
Herman, J.G.5
-
16
-
-
0035798660
-
A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box
-
Hanada, T., Yoshida, T., Kinjyo, I., Minoguchi, S., Yasukawa, H., Kato, S., Mimata, H., Nomura, Y., Seki, Y., Kubo, M. & Yoshimura, A. (2001) A mutant form of JAB/SOCS1 augments the cytokine-induced JAK/STAT pathway by accelerating degradation of wild-type JAB/CIS family proteins through the SOCS-box. Journal of Biological Chemistry, 276, 40746-40754.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 40746-40754
-
-
Hanada, T.1
Yoshida, T.2
Kinjyo, I.3
Minoguchi, S.4
Yasukawa, H.5
Kato, S.6
Mimata, H.7
Nomura, Y.8
Seki, Y.9
Kubo, M.10
Yoshimura, A.11
-
17
-
-
0029031668
-
Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects
-
Harrison, D.A., Binari, R., Nahreini, T.S., Gilman, M. & Perrimon, N. (1995) Activation of a Drosophila Janus kinase (JAK) causes hematopoietic neoplasia and developmental defects. EMBO Journal, 14, 2857-2865.
-
(1995)
EMBO Journal
, vol.14
, pp. 2857-2865
-
-
Harrison, D.A.1
Binari, R.2
Nahreini, T.S.3
Gilman, M.4
Perrimon, N.5
-
18
-
-
0029843950
-
Methylation-specific PCR: A novel PCR assay for methylation status of CpG islands
-
Herman, J.G., Graff, J.R., Myohanen, S., Nelkin, B.D. & Baylin, S.B. (1996) Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proceedings of the National Academy of Sciences of the United States of America, 93, 9821-9826.
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, pp. 9821-9826
-
-
Herman, J.G.1
Graff, J.R.2
Myohanen, S.3
Nelkin, B.D.4
Baylin, S.B.5
-
19
-
-
0035918239
-
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2
-
Kamizono, S., Hanada, T., Yasukawa, H., Minoguchi, S., Kato, R., Minoguchi, M., Hattori, K., Hatakeyama, S., Yada, M., Morita, S., Kitamura, T., Kato, H., Nakayama, K. & Yoshimura, A. (2001) The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2. Journal of Biological Chemistry, 276, 12530-12538.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 12530-12538
-
-
Kamizono, S.1
Hanada, T.2
Yasukawa, H.3
Minoguchi, S.4
Kato, R.5
Minoguchi, M.6
Hattori, K.7
Hatakeyama, S.8
Yada, M.9
Morita, S.10
Kitamura, T.11
Kato, H.12
Nakayama, K.13
Yoshimura, A.14
-
20
-
-
0036558025
-
The SOCS box: A tale of destruction and degradation
-
Kile, B.T., Schulman, B.A., Alexander, W.S., Nicola, N.A., Martin, H.M. & Hilton, D.J. (2002) The SOCS box: a tale of destruction and degradation. Trends in Biochemical Sciences, 27, 235-241.
-
(2002)
Trends in Biochemical Sciences
, vol.27
, pp. 235-241
-
-
Kile, B.T.1
Schulman, B.A.2
Alexander, W.S.3
Nicola, N.A.4
Martin, H.M.5
Hilton, D.J.6
-
21
-
-
0028826589
-
Cellular proteins that bind the von Hippel- Lindau disease gene product: Mapping of binding domains and the effect of missense mutations
-
Kishida, T., Stackhouse, T.M., Chen, F., Lerman, M.I. & Zbar, B. (1995) Cellular proteins that bind the von Hippel- Lindau disease gene product: mapping of binding domains and the effect of missense mutations. Cancer Research, 55, 4544-4548.
-
(1995)
Cancer Research
, vol.55
, pp. 4544-4548
-
-
Kishida, T.1
Stackhouse, T.M.2
Chen, F.3
Lerman, M.I.4
Zbar, B.5
-
22
-
-
15444339209
-
A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia
-
Lacronique, V., Boureux, A., Valle, V.D., Poirel, H., Quang, C.T., Mauchauffe, M., Berthou, C., Lessard, M., Berger, R., Ghysdael, J. & Bernard, O.A. (1997) A TEL-JAK2 fusion protein with constitutive kinase activity in human leukemia. Science, 278, 1309-1312.
-
(1997)
Science
, vol.278
, pp. 1309-1312
-
-
Lacronique, V.1
Boureux, A.2
Valle, V.D.3
Poirel, H.4
Quang, C.T.5
Mauchauffe, M.6
Berthou, C.7
Lessard, M.8
Berger, R.9
Ghysdael, J.10
Bernard, O.A.11
-
23
-
-
0034653478
-
Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells
-
Lacronique, V., Boureux, A., Monni, R., Dumon, S., Mauchauffe, M., Mayeux, P., Gouilleux, F., Berger, R., Gisselbrecht, S., Ghysdael, J. & Bernard, O.A. (2000) Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells. Blood, 95, 2076-2083.
-
(2000)
Blood
, vol.95
, pp. 2076-2083
-
-
Lacronique, V.1
Boureux, A.2
Monni, R.3
Dumon, S.4
Mauchauffe, M.5
Mayeux, P.6
Gouilleux, F.7
Berger, R.8
Gisselbrecht, S.9
Ghysdael, J.10
Bernard, O.A.11
-
24
-
-
0038614944
-
SOCS3 regulates the plasticity of gp130 signaling
-
Lang, R., Pauleau, A.L., Parganas, E., Takahashi, Y., Mages, J., Ihle, J.N., Rutschman, R. & Murray, P.J. (2003) SOCS3 regulates the plasticity of gp130 signaling. Natural Immunology, 4, 546-550.
-
(2003)
Natural Immunology
, vol.4
, pp. 546-550
-
-
Lang, R.1
Pauleau, A.L.2
Parganas, E.3
Takahashi, Y.4
Mages, J.5
Ihle, J.N.6
Rutschman, R.7
Murray, P.J.8
-
25
-
-
3242749984
-
Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features
-
Lin, S.Y., Yeh, K.T., Chen, W.T., Chen, H.C., Chen, S.T., Chiou, H.Y. & Chang, J.G. (2004) Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features. Oncology Reports, 11, 341-348.
-
(2004)
Oncology Reports
, vol.11
, pp. 341-348
-
-
Lin, S.Y.1
Yeh, K.T.2
Chen, W.T.3
Chen, H.C.4
Chen, S.T.5
Chiou, H.Y.6
Chang, J.G.7
-
26
-
-
0344530291
-
Epigenetic alteration of the SOCS1 gene in chronic myeloid leukaemia
-
Liu, T.C., Lin, S.F., Chang, J.G., Yang, M.Y., Hung, S.Y. & Chang, C.S. (2003) Epigenetic alteration of the SOCS1 gene in chronic myeloid leukaemia. British Journal of Haematology, 123, 654-661.
-
(2003)
British Journal of Haematology
, vol.123
, pp. 654-661
-
-
Liu, T.C.1
Lin, S.F.2
Chang, J.G.3
Yang, M.Y.4
Hung, S.Y.5
Chang, C.S.6
-
27
-
-
0028938172
-
An amino acid substitution in the Drosophila hopTum-1 Jak kinase causes leukemia-like hematopoietic defects
-
Luo, H., Hanratty, W.P. & Dearolf, C.R. (1995) An amino acid substitution in the Drosophila hopTum-1 Jak kinase causes leukemia-like hematopoietic defects. EMBO Journal, 14, 1412-1420.
-
(1995)
EMBO Journal
, vol.14
, pp. 1412-1420
-
-
Luo, H.1
Hanratty, W.P.2
Dearolf, C.R.3
-
28
-
-
0033520467
-
SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality
-
Marine, J.C., Topham, D.J., McKay, C., Wang, D., Parganas, E., Stravopodis, D., Yoshimura, A. & Ihle, J.N. (1999) SOCS1 deficiency causes a lymphocyte-dependent perinatal lethality. Cell, 98, 609-616.
-
(1999)
Cell
, vol.98
, pp. 609-616
-
-
Marine, J.C.1
Topham, D.J.2
McKay, C.3
Wang, D.4
Parganas, E.5
Stravopodis, D.6
Yoshimura, A.7
Ihle, J.N.8
-
29
-
-
0033046429
-
Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1
-
Metcalf, D., Alexander, W.S., Elefanty, A.G., Nicola, N.A., Hilton, D.J., Starr, R., Mifsud, S. & Di Rago, L. (1999) Aberrant hematopoiesis in mice with inactivation of the gene encoding SOCS-1. Leukemia, 13, 926-934.
-
(1999)
Leukemia
, vol.13
, pp. 926-934
-
-
Metcalf, D.1
Alexander, W.S.2
Elefanty, A.G.3
Nicola, N.A.4
Hilton, D.J.5
Starr, R.6
Mifsud, S.7
Di Rago, L.8
-
30
-
-
13344295097
-
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
-
Meydan, N., Grunberger, T., Dadi, H., Shahar, M., Arpaia, E., Lapidot, Z., Leeder, J.S., Freedman, M., Cohen, A., Gazit, A., Levitzki, A. & Roifman, C.M. (1996) Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor. Nature, 379, 645-648.
-
(1996)
Nature
, vol.379
, pp. 645-648
-
-
Meydan, N.1
Grunberger, T.2
Dadi, H.3
Shahar, M.4
Arpaia, E.5
Lapidot, Z.6
Leeder, J.S.7
Freedman, M.8
Cohen, A.9
Gazit, A.10
Levitzki, A.11
Roifman, C.M.12
-
31
-
-
0029005549
-
Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I
-
Migone, T.S., Lin, J.X., Cereseto, A., Mulloy, J.C., O'Shea, J.J., Franchini, G. & Leonard, W.J. (1995) Constitutively activated Jak-STAT pathway in T cells transformed with HTLV-I. Science, 269, 79-81.
-
(1995)
Science
, vol.269
, pp. 79-81
-
-
Migone, T.S.1
Lin, J.X.2
Cereseto, A.3
Mulloy, J.C.4
O'Shea, J.J.5
Franchini, G.6
Leonard, W.J.7
-
32
-
-
0035068349
-
Inactivation of SSI-1, a JAK/STAT inhibitor, in human hepatocellular carcinomas, as revealed by two-dimensional electrophoresis
-
Nagai, H., Kim, Y.S., Lee, K.T., Chu, M.Y., Konishi, N., Fujimoto, J., Baba, M., Matsubara, K. & Emi, M. (2001) Inactivation of SSI-1, a JAK/STAT inhibitor, in human hepatocellular carcinomas, as revealed by two-dimensional electrophoresis. Journal of Hepatology, 34, 416-421.
-
(2001)
Journal of Hepatology
, vol.34
, pp. 416-421
-
-
Nagai, H.1
Kim, Y.S.2
Lee, K.T.3
Chu, M.Y.4
Konishi, N.5
Fujimoto, J.6
Baba, M.7
Matsubara, K.8
Emi, M.9
-
33
-
-
13044276245
-
Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice
-
Naka, T., Matsumoto, T., Narazaki, M., Fujimoto, M., Morita, Y., Ohsawa, Y., Saito, H., Nagasawa, T., Uchiyama, Y. & Kishimoto, T. (1998) Accelerated apoptosis of lymphocytes by augmented induction of Bax in SSI-1 (STAT-induced STAT inhibitor-1) deficient mice. Proceedings of the National Academy of Sciences of the United States of America, 95, 15577-15582.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 15577-15582
-
-
Naka, T.1
Matsumoto, T.2
Narazaki, M.3
Fujimoto, M.4
Morita, Y.5
Ohsawa, Y.6
Saito, H.7
Nagasawa, T.8
Uchiyama, Y.9
Kishimoto, T.10
-
34
-
-
0032573161
-
Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling
-
Narazaki, M., Fujimoto, M., Matsumoto, T., Morita, Y., Saito, H., Kajita, T., Yoshizaki, K., Naka, T. & Kishimoto, T. (1998) Three distinct domains of SSI-1/SOCS-1/JAB protein are required for its suppression of interleukin 6 signaling. Proceedings of the National Academy of Sciences of the United States of America, 95, 13130-13134.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 13130-13134
-
-
Narazaki, M.1
Fujimoto, M.2
Matsumoto, T.3
Morita, Y.4
Saito, H.5
Kajita, T.6
Yoshizaki, K.7
Naka, T.8
Kishimoto, T.9
-
35
-
-
0033555258
-
Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction
-
Nicholson, S.E., Willson, T.A., Farley, A., Starr, R., Zhang, J.G., Baca, M., Alexander, W.S., Metcalf, D., Hilton, D.J. & Nicola, N.A. (1999) Mutational analyses of the SOCS proteins suggest a dual domain requirement but distinct mechanisms for inhibition of LIF and IL-6 signal transduction. EMBO Journal, 18, 375-385.
-
(1999)
EMBO Journal
, vol.18
, pp. 375-385
-
-
Nicholson, S.E.1
Willson, T.A.2
Farley, A.3
Starr, R.4
Zhang, J.G.5
Baca, M.6
Alexander, W.S.7
Metcalf, D.8
Hilton, D.J.9
Nicola, N.A.10
-
36
-
-
0036233585
-
Cytokine signaling in 2002: New surprises in the Jak/Stat pathway
-
O'Shea, J.J., Gadina, M. & Schreiber, R.D. (2002) Cytokine signaling in 2002: new surprises in the Jak/Stat pathway. Cell, 109(suppl.), 121-131.
-
(2002)
Cell
, vol.109
, Issue.SUPPL.
, pp. 121-131
-
-
O'Shea, J.J.1
Gadina, M.2
Schreiber, R.D.3
-
37
-
-
0030852328
-
Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia
-
Peeters, P., Raynaud, S.D., Cools, J., Wlodarska, I., Grosgeorge, J., Philip, P., Monpoux, F., Van Rompaey, L., Baens, M., Van den Berghe, H. & Marynen, P. (1997) Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. Blood, 90, 2535-2540.
-
(1997)
Blood
, vol.90
, pp. 2535-2540
-
-
Peeters, P.1
Raynaud, S.D.2
Cools, J.3
Wlodarska, I.4
Grosgeorge, J.5
Philip, P.6
Monpoux, F.7
Van Rompaey, L.8
Baens, M.9
Van Den Berghe, H.10
Marynen, P.11
-
38
-
-
0037182762
-
The tumor suppressor activity of SOCS-1
-
Rottapel, R., Ilangumaran, S., Neale, C., La Rose, J., Ho, J.M., Nguyen, M.H., Barber, D., Dubreuil, P. & de Sepulveda, P. (2002) The tumor suppressor activity of SOCS-1. Oncogene, 21, 4351-4362.
-
(2002)
Oncogene
, vol.21
, pp. 4351-4362
-
-
Rottapel, R.1
Ilangumaran, S.2
Neale, C.3
La Rose, J.4
Ho, J.M.5
Nguyen, M.H.6
Barber, D.7
Dubreuil, P.8
De Sepulveda, P.9
-
39
-
-
0034120709
-
IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma
-
Saito, H., Morita, Y., Fujimoto, M., Narazaki, M., Naka, T. & Kishimoto, T. (2000) IFN regulatory factor-1-mediated transcriptional activation of mouse STAT-induced STAT inhibitor-1 gene promoter by IFN-gamma. Journal of Immunology, 164, 5833-5843.
-
(2000)
Journal of Immunology
, vol.164
, pp. 5833-5843
-
-
Saito, H.1
Morita, Y.2
Fujimoto, M.3
Narazaki, M.4
Naka, T.5
Kishimoto, T.6
-
40
-
-
0032530972
-
Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes
-
Schwaller, J., Frantsve, J., Aster, J., Williams, I.R., Tomasson, M.H., Ross, T.S., Peeters, P., Van Rompaey, L., Van Etten, R.A., Ilaria, R. Jr., Marynen, P. & Gilliland, D.G. (1998) Transformation of hematopoietic cell lines to growth-factor independence and induction of a fatal myelo- and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes. EMBO Journal, 17, 5321-5333.
-
(1998)
EMBO Journal
, vol.17
, pp. 5321-5333
-
-
Schwaller, J.1
Frantsve, J.2
Aster, J.3
Williams, I.R.4
Tomasson, M.H.5
Ross, T.S.6
Peeters, P.7
Van Rompaey, L.8
Van Etten, R.A.9
Ilaria Jr., R.10
Marynen, P.11
Gilliland, D.G.12
-
41
-
-
0030792590
-
A family of cytokine-inducible inhibitors of signalling
-
Starr, R., Willson, T.A., Viney, E.M., Murray, L.J., Rayner, J.R., Jenkins, B.J., Gonda, T.J., Alexander, W.S., Metcalf, D., Nicola, N.A. & Hilton, D.J. (1997) A family of cytokine-inducible inhibitors of signalling. Nature, 387, 917-921.
-
(1997)
Nature
, vol.387
, pp. 917-921
-
-
Starr, R.1
Willson, T.A.2
Viney, E.M.3
Murray, L.J.4
Rayner, J.R.5
Jenkins, B.J.6
Gonda, T.J.7
Alexander, W.S.8
Metcalf, D.9
Nicola, N.A.10
Hilton, D.J.11
-
42
-
-
0032564463
-
Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1
-
Starr, R., Metcalf, D., Elefanty, A.G., Brysha, M., Willson, T.A., Nicola, N.A., Hilton, D.J. & Alexander, W.S. (1998) Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1. Proceedings of the National Academy of Sciences of the United States of America, 95, 14395-14399.
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, pp. 14395-14399
-
-
Starr, R.1
Metcalf, D.2
Elefanty, A.G.3
Brysha, M.4
Willson, T.A.5
Nicola, N.A.6
Hilton, D.J.7
Alexander, W.S.8
-
43
-
-
0035914314
-
Four tyrosine residues in phospholipase C-gamma 2, identified as Btk- Dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling
-
Watanabe, D., Hashimoto, S., Ishiai, M., Matsushita, M., Baba, Y., Kishimoto, T., Kurosaki, T. & Tsukada, S. (2001) Four tyrosine residues in phospholipase C-gamma 2, identified as Btk- dependent phosphorylation sites, are required for B cell antigen receptor-coupled calcium signaling. Journal of Biological Chemistry, 276, 38595-38601.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 38595-38601
-
-
Watanabe, D.1
Hashimoto, S.2
Ishiai, M.3
Matsushita, M.4
Baba, Y.5
Kishimoto, T.6
Kurosaki, T.7
Tsukada, S.8
-
44
-
-
0037600741
-
IL-6 induces an antiinflammatory response in the absence of SOCS3 in macrophages
-
Yasukawa, H., Ohishi, M., Mori, H., Murakami, M., Chinen, T., Aki, D., Hanada, T., Takeda, K., Akira, S., Hoshijima, M., Hirano, T., Chien, K.R. & Yoshimura, A. (2003) IL-6 induces an antiinflammatory response in the absence of SOCS3 in macrophages. Nature Immunology, 4, 551-556.
-
(2003)
Nature Immunology
, vol.4
, pp. 551-556
-
-
Yasukawa, H.1
Ohishi, M.2
Mori, H.3
Murakami, M.4
Chinen, T.5
Aki, D.6
Hanada, T.7
Takeda, K.8
Akira, S.9
Hoshijima, M.10
Hirano, T.11
Chien, K.R.12
Yoshimura, A.13
-
45
-
-
0035042611
-
SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity
-
Yoshikawa, H., Matsubara, K., Qian, G.S., Jackson, P., Groopman, J.D., Manning, J.E., Harris, C.C. & Herman, J.G. (2001) SOCS-1, a negative regulator of the JAK/STAT pathway, is silenced by methylation in human hepatocellular carcinoma and shows growth-suppression activity. Nature Genetics, 28, 29-35.
-
(2001)
Nature Genetics
, vol.28
, pp. 29-35
-
-
Yoshikawa, H.1
Matsubara, K.2
Qian, G.S.3
Jackson, P.4
Groopman, J.D.5
Manning, J.E.6
Harris, C.C.7
Herman, J.G.8
-
46
-
-
0242407711
-
Negative regulation of cytokine signaling influences inflammation
-
Yoshimura, A., Mori, H., Ohishi, M., Aki, D. & Hanada, T. (2003) Negative regulation of cytokine signaling influences inflammation. Current Opinion in Immunology, 15, 704-708.
-
(2003)
Current Opinion in Immunology
, vol.15
, pp. 704-708
-
-
Yoshimura, A.1
Mori, H.2
Ohishi, M.3
Aki, D.4
Hanada, T.5
-
47
-
-
0029834676
-
Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome
-
Zhang, Q., Nowak, I., Vonderheid, E.C., Rook, A.H., Kadin, M.E., Nowell, P.C., Shaw, L.M. & Wasik, M.A. (1996) Activation of Jak/STAT proteins involved in signal transduction pathway mediated by receptor for interleukin 2 in malignant T lymphocytes derived from cutaneous anaplastic large T-cell lymphoma and Sezary syndrome. Proceedings of the National Academy of Sciences of the United States of America, 93, 9148-9153.
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, pp. 9148-9153
-
-
Zhang, Q.1
Nowak, I.2
Vonderheid, E.C.3
Rook, A.H.4
Kadin, M.E.5
Nowell, P.C.6
Shaw, L.M.7
Wasik, M.A.8
|