Administration of the immunophilin ligand FK506 differentially attenuates neurofilament compaction and impaired axonal transport in injured axons following diffuse traumatic brain injury

Experimental Neurology

Volumn 197, Issue 2, 2006, Pages 353-362

  Marmarou, Christina R ^a   Povlishock, John T ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Amyloid precursor protein (APP); Axonal damage; FK506; Immunophilin ligands; Neurofilament compaction (NFC); Traumatic brain injury

Indexed keywords

AMYLOID PRECURSOR PROTEIN; FK 506 BINDING PROTEIN; IMMUNOPHILIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; AXONAL INJURY; CONTROLLED STUDY; DISEASE COURSE; DRUG EFFECT; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY; NERVE FIBER TRANSPORT; NEUROFILAMENT; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE PREPARATION; TRAUMATIC BRAIN INJURY;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; AXONAL TRANSPORT; BRAIN INJURIES; DIFFUSE AXONAL INJURY; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; MALE; NEUROFILAMENT PROTEINS; NEUROLOGIC EXAMINATION; PYRAMIDAL TRACTS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; TACROLIMUS; TIME FACTORS;

EID: 30444454199     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2005.10.003     Document Type: Article

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