Mild hypothermia enhances the neuroprotective effects of FK506 and expands its therapeutic window following transient focal ischemia in rats

Brain Research

Volumn 1008, Issue 2, 2004, Pages 179-185

  Nito, Chikako ^a   Kamiya, Tatsushi ^a   Ueda, Masayuki ^a   Arii, Takako ^a   Katayama, Yasuo ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

Disorders of the nervous system; FK506; Focal ischemia; Hypothermia; Ischemia; Neuroprotection; Rat

Indexed keywords

DRUG VEHICLE; TACROLIMUS;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; BRAIN CORTEX; BRAIN EDEMA; BRAIN INFARCTION; BRAIN INJURY; BRAIN ISCHEMIA; CONTROLLED STUDY; CORPUS STRIATUM; CRYOTHERAPY; EVALUATION; HYPOTHERMIA; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NONHUMAN; PERFORMANCE; PRIORITY JOURNAL; RAT; RECTUM TEMPERATURE; REPERFUSION; TEMPORALIS MUSCLE; TREATMENT OUTCOME;

ANIMALS; BODY TEMPERATURE; BRAIN EDEMA; CEREBRAL INFARCTION; CEREBROVASCULAR CIRCULATION; HYPOTHERMIA, INDUCED; IMMUNOSUPPRESSIVE AGENTS; ISCHEMIC ATTACK, TRANSIENT; LASER-DOPPLER FLOWMETRY; MALE; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; TACROLIMUS;

EID: 2442431643     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.02.031     Document Type: Article

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