Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 8, 1996, Pages 3428-3433

  Saatman, Kathryn E ^a   Murai, Hisayuki ^a   Bartus, Raymond T ^b   Smith, Douglas H ^a   Hayward, Neil J ^b   Perri, Brian R ^a   McIntosh, Tracy K ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b ALKERMES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AK 295; CALPAIN; CALPASTATIN; MORPHOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; COGNITIVE DEFECT; CONTINUOUS INFUSION; CONTROLLED STUDY; DRUG EFFICACY; INTRAARTERIAL DRUG ADMINISTRATION; MALE; MAZE TEST; MEMORY CONSOLIDATION; MOTOR DYSFUNCTION; MOTOR PERFORMANCE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SCORING SYSTEM; TASK PERFORMANCE; WALKING;

ANIMALS; BRAIN INJURIES; CALPAIN; COGNITION DISORDERS; CYSTEINE PROTEINASE INHIBITORS; DIPEPTIDES; DISEASE MODELS, ANIMAL; MALE; MEMORY; PSYCHOMOTOR PERFORMANCE; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA;

EID: 0030004873     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.8.3428     Document Type: Article

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