메뉴 건너뛰기




Volumn 58, Issue 4, 1999, Pages 365-375

The role of calpain-mediated spectrin proteolysis in traumatically induced axonal injury

Author keywords

Axonal injury; Calcium; Calpain; Cytoskeleton; Immunohistochemistry; Spectrin; Traumatic brain injury

Indexed keywords

CALPAIN; SPECTRIN;

EID: 0032944441     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199904000-00007     Document Type: Article
Times cited : (218)

References (51)
  • 2
    • 0023686594 scopus 로고
    • Axonal damage in severe traumatic brain injury: An experimental study in cat
    • Erb DE, Povlishock JT. Axonal damage in severe traumatic brain injury: An experimental study in cat. Acta Neuropathol 1988;76:347-58
    • (1988) Acta Neuropathol , vol.76 , pp. 347-358
    • Erb, D.E.1    Povlishock, J.T.2
  • 3
    • 0027234432 scopus 로고
    • Ultrastructural evidence of axonal shearing as a result of lateral accaleration of the head in non-human primates
    • Maxwell WL, Watt C, Graham DI, Gennarelli TA. Ultrastructural evidence of axonal shearing as a result of lateral accaleration of the head in non-human primates. Acta Neuropathol 1993;86:136-44
    • (1993) Acta Neuropathol , vol.86 , pp. 136-144
    • Maxwell, W.L.1    Watt, C.2    Graham, D.I.3    Gennarelli, T.A.4
  • 4
    • 0030752893 scopus 로고    scopus 로고
    • A mechanistic analysis of non disruptive axonal injury: A review
    • Maxwell WL, Povlishock JT, Graham DL. A mechanistic analysis of non disruptive axonal injury: a review. J Neurotrauma 1997; 14:419-40
    • (1997) J Neurotrauma , vol.14 , pp. 419-440
    • Maxwell, W.L.1    Povlishock, J.T.2    Graham, D.L.3
  • 5
    • 0029896102 scopus 로고    scopus 로고
    • Characterization of a distinct set of intraaxonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability
    • Pettus EH, Povlishock JT. Characterization of a distinct set of intraaxonal ultrastructural changes associated with traumatically induced alteration in axolemmal permeability. Brain Res 1996;722:1-11
    • (1996) Brain Res , vol.722 , pp. 1-11
    • Pettus, E.H.1    Povlishock, J.T.2
  • 8
    • 0028808165 scopus 로고
    • Are the pathobiological changes evoked by traumatic brain injury immediate and irreversible?
    • Povlishock JT, Jenkins LW. Are the pathobiological changes evoked by traumatic brain injury immediate and irreversible? Brain Path 1995;5:415-26
    • (1995) Brain Path , vol.5 , pp. 415-426
    • Povlishock, J.T.1    Jenkins, L.W.2
  • 9
    • 0028152764 scopus 로고
    • Traumatically induced altered membrane permeability: Its relationship to traumatically induced reactive axonal change
    • Pettus EH, Christman CW, Giebel ML, Povlishock JT. Traumatically induced altered membrane permeability: Its relationship to traumatically induced reactive axonal change. J Neurotrauma 1994; 11:507-22
    • (1994) J Neurotrauma , vol.11 , pp. 507-522
    • Pettus, E.H.1    Christman, C.W.2    Giebel, M.L.3    Povlishock, J.T.4
  • 10
    • 0030725073 scopus 로고    scopus 로고
    • Impact acceleration injury in the rat: Evidence for focal axolemmal change and related neurofilament sidearm alteration
    • Povlishock JT, Marmarou A, McIntosh T, Trojanowski JQ, Moroi J. Impact acceleration injury in the rat: Evidence for focal axolemmal change and related neurofilament sidearm alteration. J Neuropathol Exp Neurol 1997;56:347-59
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 347-359
    • Povlishock, J.T.1    Marmarou, A.2    McIntosh, T.3    Trojanowski, J.Q.4    Moroi, J.5
  • 11
    • 0032536329 scopus 로고    scopus 로고
    • Alteration of the neurofilament sidearm and its relation to neurofilament compaction occurring with traumatic axonal injury
    • Okonkwo DO, Pettus EH, Moroi J, Povlishock JT. Alteration of the neurofilament sidearm and its relation to neurofilament compaction occurring with traumatic axonal injury. Brain Res 1998;784:1-6
    • (1998) Brain Res , vol.784 , pp. 1-6
    • Okonkwo, D.O.1    Pettus, E.H.2    Moroi, J.3    Povlishock, J.T.4
  • 12
    • 0018132354 scopus 로고
    • Pathology of experimental spinal cord trauma. II. Ultrastructure of axons and myelin
    • Balentine JD, Paris DU. Pathology of experimental spinal cord trauma. II. Ultrastructure of axons and myelin. Lab Invest 1978;39: 254-66
    • (1978) Lab Invest , vol.39 , pp. 254-266
    • Balentine, J.D.1    Paris, D.U.2
  • 13
    • 0030015166 scopus 로고    scopus 로고
    • Normal and abnormal calcium homeostasis in neurons: A basis for the pathophysiology of traumatic and ischemic central nervous system injury
    • Tymianski M, Tator CH. Normal and abnormal calcium homeostasis in neurons: A basis for the pathophysiology of traumatic and ischemic central nervous system injury. Neurosurgery 1996;38: 1176-95
    • (1996) Neurosurgery , vol.38 , pp. 1176-1195
    • Tymianski, M.1    Tator, C.H.2
  • 14
    • 0001454672 scopus 로고    scopus 로고
    • The calpain hypothesis of neurodegeneration: Evidence for a common cytotoxic pathway
    • Bartus RT. The calpain hypothesis of neurodegeneration: evidence for a common cytotoxic pathway. Neuroscientist 1997;3:314-27
    • (1997) Neuroscientist , vol.3 , pp. 314-327
    • Bartus, R.T.1
  • 15
    • 0030951668 scopus 로고    scopus 로고
    • Mechanism of calpain proteolysis following traumatic brain injury: Implications for pathology and therapy: A review and update
    • Kampfl A, Posmantur RM, Zhao X, Schmutzhard E, Clifton GL, Hayes RL. Mechanism of calpain proteolysis following traumatic brain injury: Implications for pathology and therapy: A review and update. J Neurotrauma 1997;14:121-34
    • (1997) J Neurotrauma , vol.14 , pp. 121-134
    • Kampfl, A.1    Posmantur, R.M.2    Zhao, X.3    Schmutzhard, E.4    Clifton, G.L.5    Hayes, R.L.6
  • 16
    • 0021273261 scopus 로고
    • Brain fodrin: Substrate for calpain I, an endogenous calcium-activated protease
    • Siman R, Baudry M, Lynch G. Brain fodrin: Substrate for calpain I, an endogenous calcium-activated protease. Proc Natl Acad Sci USA 1984;81:3572-76
    • (1984) Proc Natl Acad Sci USA , vol.81 , pp. 3572-3576
    • Siman, R.1    Baudry, M.2    Lynch, G.3
  • 17
    • 0028282502 scopus 로고
    • Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain
    • Roberts-Lewis JM, Savage MJ, Marcy VR, Pinsker LR, Siman R. Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain. J Neurosci 1994; 14:3934-44
    • (1994) J Neurosci , vol.14 , pp. 3934-3944
    • Roberts-Lewis, J.M.1    Savage, M.J.2    Marcy, V.R.3    Pinsker, L.R.4    Siman, R.5
  • 18
    • 0022518521 scopus 로고
    • Spectrin subtypes in mammalian brain: An immunoelectron microscopic study
    • Zagon IS, Higbee R, Riederer BM, Goodman SR. Spectrin subtypes in mammalian brain: An immunoelectron microscopic study. J Neurosci 1986;6:2977-86
    • (1986) J Neurosci , vol.6 , pp. 2977-2986
    • Zagon, I.S.1    Higbee, R.2    Riederer, B.M.3    Goodman, S.R.4
  • 19
    • 0030037390 scopus 로고    scopus 로고
    • Prolonged calpain-mediated spectrin breakdown occurs regionally following experimental brain injury in the rat
    • Saatman KE, Bozyczko-Coyne D, Marcy V, Siman R, McIntosh TK. Prolonged calpain-mediated spectrin breakdown occurs regionally following experimental brain injury in the rat. J Neuropathol Exp Neurol 1996;55:850-60
    • (1996) J Neuropathol Exp Neurol , vol.55 , pp. 850-860
    • Saatman, K.E.1    Bozyczko-Coyne, D.2    Marcy, V.3    Siman, R.4    McIntosh, T.K.5
  • 20
    • 0030872701 scopus 로고    scopus 로고
    • Immunohistochemical study of calpain-mediated breakdown products to α-spectrin following controlled cortical impact injury in the rat
    • Newcomb J, Kampfl A, Posmantur RM, Zhao X, Pike BR, Liu SJ, Clifton GL, Hayes RL Immunohistochemical study of calpain-mediated breakdown products to α-spectrin following controlled cortical impact injury in the rat. J Neurotrauma 1997;14:369-83
    • (1997) J Neurotrauma , vol.14 , pp. 369-383
    • Newcomb, J.1    Kampfl, A.2    Posmantur, R.M.3    Zhao, X.4    Pike, B.R.5    Liu, S.J.6    Clifton, G.L.7    Hayes, R.L.8
  • 21
    • 0031550631 scopus 로고    scopus 로고
    • A calpain inhibitor attenuates cortical cytoskeletal protein loss after experimental brain injury in the rat
    • Posmantur R, Kampfl A., Siman R, et al. A calpain inhibitor attenuates cortical cytoskeletal protein loss after experimental brain injury in the rat. Neuroscience 1997;77:875-88
    • (1997) Neuroscience , vol.77 , pp. 875-888
    • Posmantur, R.1    Kampfl, A.2    Siman, R.3
  • 22
    • 0029131247 scopus 로고
    • Role of calpain in spinal cord injury: Increased m-calpain immunoreactivity in spinal cord after compression injury in the rat
    • Li Z, Hogan EL, Banik NL. Role of calpain in spinal cord injury: Increased m-calpain immunoreactivity in spinal cord after compression injury in the rat. Neurochem Int 1995;27:425-32
    • (1995) Neurochem Int , vol.27 , pp. 425-432
    • Li, Z.1    Hogan, E.L.2    Banik, N.L.3
  • 23
    • 0029896181 scopus 로고    scopus 로고
    • Role of calpain in spinal cord injury: Increased m-caplain immunoreactivity in rat spinal cord after impact trauma
    • Li Z, Hogan EL, Banik NL. Role of calpain in spinal cord injury: Increased m-caplain immunoreactivity in rat spinal cord after impact trauma. Neurochem Res 1996;21:441-48
    • (1996) Neurochem Res , vol.21 , pp. 441-448
    • Li, Z.1    Hogan, E.L.2    Banik, N.L.3
  • 24
    • 0030729804 scopus 로고    scopus 로고
    • Role of calpain and its inhibitors in tissue degeneration and neuroprotection in spinal cord injury
    • Banik NL, Matzelle D, Gantt-Wilford G, Hogan EL. Role of calpain and its inhibitors in tissue degeneration and neuroprotection in spinal cord injury. Ann N Y Acad Sci 1997;844:120-27
    • (1997) Ann N Y Acad Sci , vol.844 , pp. 120-127
    • Banik, N.L.1    Matzelle, D.2    Gantt-Wilford, G.3    Hogan, E.L.4
  • 25
    • 0031002146 scopus 로고    scopus 로고
    • Increased calpain content and progressive degradation of neurofilament protein in spinal cord injury
    • Banik NL, Matzelle DC, Gantt-Wilford G, Osborne A, Hogan EL Increased calpain content and progressive degradation of neurofilament protein in spinal cord injury. Brain Res 1997;752:301-6
    • (1997) Brain Res , vol.752 , pp. 301-306
    • Banik, N.L.1    Matzelle, D.C.2    Gantt-Wilford, G.3    Osborne, A.4    Hogan, E.L.5
  • 26
    • 0028085099 scopus 로고
    • A new model of diffuse brain injury in rats. Part II: Morphological characterization
    • Foda MAA-E, Marmarou A. A new model of diffuse brain injury in rats. Part II: Morphological characterization. J Neurosurg 1994; 80:301-13
    • (1994) J Neurosurg , vol.80 , pp. 301-313
    • Foda, M.A.A.-E.1    Marmarou, A.2
  • 28
    • 0345069975 scopus 로고    scopus 로고
    • The EM visualization of antibodies targeted to amyloid precursor proteins in axons undergoing traumatically induced reactive change
    • in press
    • Stone JP, Christman CW, Povlishock JT. The EM visualization of antibodies targeted to amyloid precursor proteins in axons undergoing traumatically induced reactive change. Acta Neuropathol 1999 (in press)
    • (1999) Acta Neuropathol
    • Stone, J.P.1    Christman, C.W.2    Povlishock, J.T.3
  • 29
    • 0031843505 scopus 로고    scopus 로고
    • Post-traumatic hypothermia protects against axonal damage in an animal model of traumatic axonal injury
    • Koizumi H and Povlishock JT. Post-traumatic hypothermia protects against axonal damage in an animal model of traumatic axonal injury. J Neurosurg 1998;89:303-9
    • (1998) J Neurosurg , vol.89 , pp. 303-309
    • Koizumi, H.1    Povlishock, J.T.2
  • 30
    • 0024363137 scopus 로고
    • Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage
    • Siman R, Noszek JC, Kegerise C. Calpain I activation is specifically related to excitatory amino acid induction of hippocampal damage. J Neurosci 1989;9:1579-90
    • (1989) J Neurosci , vol.9 , pp. 1579-1590
    • Siman, R.1    Noszek, J.C.2    Kegerise, C.3
  • 31
    • 0023520075 scopus 로고
    • Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats
    • Lee VM, Carden MJ, Schlaepfer WW, Trojanowski JQ. Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats. J Neurosci 1987;7:3474-88
    • (1987) J Neurosci , vol.7 , pp. 3474-3488
    • Lee, V.M.1    Carden, M.J.2    Schlaepfer, W.W.3    Trojanowski, J.Q.4
  • 32
    • 0028972780 scopus 로고
    • The use of peroxidase substrate vector VIP in electron microscopic single and double antigen localization
    • Zhou M, Grofova I. The use of peroxidase substrate Vector VIP in electron microscopic single and double antigen localization. J Neurosci Methods 1995;62:149-58
    • (1995) J Neurosci Methods , vol.62 , pp. 149-158
    • Zhou, M.1    Grofova, I.2
  • 33
    • 0022469165 scopus 로고
    • A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride
    • Levey AI, Bolam JP, Rye DB, et al. A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride. J Histochem Cytochem 1986;34:1449-57
    • (1986) J Histochem Cytochem , vol.34 , pp. 1449-1457
    • Levey, A.I.1    Bolam, J.P.2    Rye, D.B.3
  • 34
    • 0031038495 scopus 로고    scopus 로고
    • Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro
    • Faddis BT, Hasbani MJ, Goldberg MP Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro. J Neurosci 1997;17:951-59
    • (1997) J Neurosci , vol.17 , pp. 951-959
    • Faddis, B.T.1    Hasbani, M.J.2    Goldberg, M.P.3
  • 35
    • 0030930824 scopus 로고    scopus 로고
    • Rapid calpain I activation and cytoskeletal protein degradation following traumatic spinal cord injury: Attenuation with riluzole pretreatment
    • Springer JE, Azbill RD, Kennedy SE, George J, Geddes JW. Rapid calpain I activation and cytoskeletal protein degradation following traumatic spinal cord injury: Attenuation with riluzole pretreatment. J Neurochem 1997;69:1592-1600
    • (1997) J Neurochem , vol.69 , pp. 1592-1600
    • Springer, J.E.1    Azbill, R.D.2    Kennedy, S.E.3    George, J.4    Geddes, J.W.5
  • 36
    • 0029691406 scopus 로고    scopus 로고
    • Traumatically induced axonal damage: Evidence for enduring changes in axolemmal permeability with associated cytoskeletal change
    • Povlishock JT, Pettus EH. Traumatically induced axonal damage: Evidence for enduring changes in axolemmal permeability with associated cytoskeletal change. Acta Neurochir Suppl (Wien) 1996; 66:81-86
    • (1996) Acta Neurochir Suppl (Wien) , vol.66 , pp. 81-86
    • Povlishock, J.T.1    Pettus, E.H.2
  • 37
    • 0032496737 scopus 로고    scopus 로고
    • Nigral innervation of cholinergic and glutaminergic cells in the rat mesopontine tegmentum: Light and electron microscopic anterograde tracing and immunohistochemical studies
    • Grofova I, Zhou M. Nigral innervation of cholinergic and glutaminergic cells in the rat mesopontine tegmentum: Light and electron microscopic anterograde tracing and immunohistochemical studies. J Comp Neurol 1998;395:359-79
    • (1998) J Comp Neurol , vol.395 , pp. 359-379
    • Grofova, I.1    Zhou, M.2
  • 38
    • 0031916103 scopus 로고    scopus 로고
    • Subcellular localization and duration of mu-calpain and m-calpain activity after traumatic brain injury in the rat: A casein zymography study
    • Zhao X, Posmantur R, Kampfl A, et al. Subcellular localization and duration of mu-calpain and m-calpain activity after traumatic brain injury in the rat: A casein zymography study. J Cereb Blood Flow Metab 1998;18:161-67
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 161-167
    • Zhao, X.1    Posmantur, R.2    Kampfl, A.3
  • 39
    • 0019951391 scopus 로고
    • Calcium-induced spongiform and necrotizing myelopathy
    • Balentine JD, Dean DL Jr. Calcium-induced spongiform and necrotizing myelopathy. Lab Invest 1982;47:286-95
    • (1982) Lab Invest , vol.47 , pp. 286-295
    • Balentine, J.D.1    Dean D.L., Jr.2
  • 40
    • 0026044081 scopus 로고
    • Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice
    • Peters LL, Birkenmeier CS, Bronson RT, et al. Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice. J Cell Biol 1991;114:1233-41
    • (1991) J Cell Biol , vol.114 , pp. 1233-1241
    • Peters, L.L.1    Birkenmeier, C.S.2    Bronson, R.T.3
  • 42
    • 0029126491 scopus 로고
    • Two strategies to prepare neural cortical cytoskeleton components for the generation of monoclonal antibodies
    • Mack TG, Schulz O, Pollerberg GE. Two strategies to prepare neural cortical cytoskeleton components for the generation of monoclonal antibodies. Eur J Cell Biol 1995;67:218-26
    • (1995) Eur J Cell Biol , vol.67 , pp. 218-226
    • Mack, T.G.1    Schulz, O.2    Pollerberg, G.E.3
  • 43
    • 0028784721 scopus 로고
    • Interaction of brain spectrin (fodrin) with phospholipids
    • Diakowski W, Sikorski AF. Interaction of brain spectrin (fodrin) with phospholipids. Biochemistry 1995;34:13252-58
    • (1995) Biochemistry , vol.34 , pp. 13252-13258
    • Diakowski, W.1    Sikorski, A.F.2
  • 44
    • 0030443956 scopus 로고    scopus 로고
    • Molecular composition of the node of Ranvier: Identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segments
    • Davis JQ, Lambert S, Bennett V. Molecular composition of the node of Ranvier: Identification of ankyrin-binding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segments. J Cell Biol 1996;135:1355-67
    • (1996) J Cell Biol , vol.135 , pp. 1355-1367
    • Davis, J.Q.1    Lambert, S.2    Bennett, V.3
  • 45
    • 0023014152 scopus 로고
    • Differentiation state-dependent surface mobilities of two forms of the neural cell adhesion molecule
    • Pollerberg GE, Schachner M, Davoust J. Differentiation state-dependent surface mobilities of two forms of the neural cell adhesion molecule. Nature 1986;324:462-65
    • (1986) Nature , vol.324 , pp. 462-465
    • Pollerberg, G.E.1    Schachner, M.2    Davoust, J.3
  • 46
    • 0025955448 scopus 로고
    • In vitro proteolysis of brain spectrin by calpain I inhibits association of spectrin with ankyrin-independent membrane binding site(s)
    • Hu RJ, Bennett V. In vitro proteolysis of brain spectrin by calpain I inhibits association of spectrin with ankyrin-independent membrane binding site(s). J Biol Chem 1991;266:18200-5
    • (1991) J Biol Chem , vol.266 , pp. 18200-18205
    • Hu, R.J.1    Bennett, V.2
  • 47
    • 0026524937 scopus 로고
    • Actin and neurofilament binding domain of brain spectrin beta subunit
    • Frappier T, Derancourt J, Pradel LA. Actin and neurofilament binding domain of brain spectrin beta subunit. Eur J Biochem 1992; 205:85-91
    • (1992) Eur J Biochem , vol.205 , pp. 85-91
    • Frappier, T.1    Derancourt, J.2    Pradel, L.A.3
  • 48
    • 0032550159 scopus 로고    scopus 로고
    • Temporal ordering of pathogenic events following transient global ischemia
    • Bartus RT, Dean RL, Mennerick S, Eveleth D, Lynch G. Temporal ordering of pathogenic events following transient global ischemia. Brain Res 1998;790:1-13
    • (1998) Brain Res , vol.790 , pp. 1-13
    • Bartus, R.T.1    Dean, R.L.2    Mennerick, S.3    Eveleth, D.4    Lynch, G.5
  • 49
    • 0032575377 scopus 로고    scopus 로고
    • Simultaneous degradation of alphaII-and betaII-spectrin by caspase 3 (CPP32) in apoptotic cells
    • Wang KKW, Posmantur R, Nath R, et al. Simultaneous degradation of alphaII-and betaII-spectrin by caspase 3 (CPP32) in apoptotic cells. J Biol Chem 1998;273:22490-97
    • (1998) J Biol Chem , vol.273 , pp. 22490-22497
    • Wang, K.K.W.1    Posmantur, R.2    Nath, R.3
  • 50
    • 0026435098 scopus 로고
    • Traumatically induced axonal injury: Pathogenesis and pathobiological implications
    • Povlishock JT Traumatically induced axonal injury: Pathogenesis and pathobiological implications. Brain Path 1992;2:1-12
    • (1992) Brain Path , vol.2 , pp. 1-12
    • Povlishock, J.T.1
  • 51
    • 0030004873 scopus 로고    scopus 로고
    • Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat
    • Saatman KE, Murai H, Bartus RT, et al. Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat. Proc Natl Acad Sci USA 1996;93:3428-33
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 3428-3433
    • Saatman, K.E.1    Murai, H.2    Bartus, R.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.