Regional distribution of neuritic plaques in the nondemented elderly and subjects with very mild Alzheimer Disease

Archives of Neurology

Volumn 55, Issue 9, 1998, Pages 1185-1191

  Haroutunian, Vahram ^a   Perl, Daniel P ^b   Purohit, Dushyant P ^c   Marin, Deborah ^b   Khan, Khalid ^a   Lantz, Melinda ^a   Davis, Kenneth L ^a   Mohs, Richard C ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Jewish Home and Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; ALZHEIMER DISEASE; AMYGDALOID NUCLEUS; ARTICLE; CONTROLLED STUDY; DEMENTIA; DISEASE SEVERITY; ENTORHINAL CORTEX; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; NEOCORTEX; NEUROPATHOLOGY; NURSING HOME; PRIORITY JOURNAL; SENILE PLAQUE;

AGED; AGED, 80 AND OVER; AGING; ALZHEIMER DISEASE; BRAIN; COGNITION; DEMENTIA; FEMALE; HOMES FOR THE AGED; HUMANS; MALE; NURSING HOMES; SENILE PLAQUES;

EID: 0031781988     PISSN: 00039942     EISSN: None     Source Type: Journal    
DOI: 10.1001/archneur.55.9.1185     Document Type: Article

References (24)

1. Rogers J, Morrison JH. Quantitative morphology and regional and laminar distribution of senile plaques in Alzheimer's disease. J Neurosci. 1985;5:2801-2808.
2. Tomlinson BE, Blessed G, Roth M. Observations on the brains of demented old people. J Neurol Sci. 1970;11:205-242.
3. Khachaturian ZS. Diagnosis of Alzheimer's disease. Arch Neurol. 1985;42:1097-1105.
4. Mirra SS, Heyman A, McKeel D, et al. The Consortium to Establish a Registry for Alzheimer's Disease (CERAD), II: standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 1991;41:479-486.
5. Selkoe DJ. Alzheimer's disease: genotypes, phenotype, and treatment. Science. 1997;275:630-631.
6. Selkoe DJ. Normal and abnormal biology of the β-amyloid precursor protein. Annu Rev Neurosci. 1994;17:489-517.
7. Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol (Berl). 1991;82:239-259.
8. Blessed G, Tomlinson BE, Roth M. The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry. 1968;114:797-811.
9. Neary D, Snowden JS, Mann DM, et al. Alzheimer's disease: a correlative study. J Neurol Neurosurg Psychiatry. 1986;49:229-237.
10. Mann DM, Marcyniuk B, Yates PO, Neary D, Snowden JS. The progression of the pathological changes of Alzheimer's disease in frontal and temporal neocortex examined both at biopsy and at autopsy. Neuropathol Appl Neurobiol. 1988;14:177-195.
11. Wilcock GK, Esiri MM. Plaques, tangles and dementia: a quantitative study. J Neurol Sci. 1982;56:343-356.
12. Price JL, Davis PB, Morris JC, White DL The distribution of tangles, plaques and related immunohistochemical markers in healthy aging and Alzheimer's disease. Neurobiol Aging. 1991;12:295-312.
13. Gomez-Isla T, Price JL, McKeel DW Jr, Morris JC, Growdon JH, Hyman BT. Profound loss of layer II entorhinal cortex neurons occurs in very mild Alzheimer's disease. J Neurosci. 1996;16:4491-4500.
14. Hughes CP, Berg L, Danziger WL, Coben LA, Martin RL A new clinical scale for the staging of dementia. Br J Psychiatry. 1982;140:566-572.
15. Morris JC. The clinical dementia rating (CDR): current version and scoring rules. Arch Neurol. 1993;43:2412-2414.
16. Morris JC, Storandt M, McKeel DW Jr, et al. Cerebral amyloid deposition and diffuse plaques in "normal" aging: evidence for presymptomatic and very mild Alzheimer's disease. Neurology. 1996;46:707-719.
17. Folstein M, Folstein S, McHugh P. "Mini-Mental State": a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189-198.
18. Rosen WG, Mohs RC, Davis KL. A new rating scale for Alzheimer's disease. Am J Psychiatry. 1984;141:1356-1364.
19. Crum RM, Anthony JC, Bassett SS, Folstein MF. Population-based norms for the Mini-Mental State Examination by age and educational level. JAMA. 1993;269:2386-2391.
20. Price JL Diagnostic criteria for Alzheimer's disease. Neurobiol Aging. 1997;18(suppl):S67-S70.
21. Terry RD, Masliah E, Salmon DP, et al. Physical basis of cognitive alterations in Alzheimer's disease: synapse loss is the major correlate of cognitive impairment. Ann Neurol. 1991;30:572-580.
22. Hyman BT. The neuropathological diagnosis of Alzheimer's disease: clinical-pathological studies. Neurobiol Aging. 1997;18(suppl):S27-S32.
23. Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology. 1992;42:631-639.
24. Bierer L, Haroutunian V, Gabriel S, et al. Neurochemical correlates of dementia severity in Alzheimer's disease: relative importance of the cholinergic deficits. J Neurochem. 1995;64:749-760.