-
1
-
-
0037424520
-
The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine
-
Abu M, Waters TR (2003) The main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosine. J Biol Chem 278:8739-8744
-
(2003)
J Biol Chem
, vol.278
, pp. 8739-8744
-
-
Abu, M.1
Waters, T.R.2
-
2
-
-
0027337609
-
Aflatoxin B1 induces the transversion of G->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes
-
Aguilar F, Hussain SP, Cerutti P (1993) Aflatoxin B1 induces the transversion of G->T in codon 249 of the p53 tumor suppressor gene in human hepatocytes. Proc Natl Acad Sci USA 90:8586-8590
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8586-8590
-
-
Aguilar, F.1
Hussain, S.P.2
Cerutti, P.3
-
3
-
-
0033528096
-
Relationship between p53 mutations and inducible nitric oxide synthase expression in human colorectal cancer
-
Ambs S, Bennett WP, Merriam WG, Ogunfusika MO, Oser SM, Harrington AM, Shields PG, Felley-Bosco E, Hussain SP, Harris CC (1999b) Relationship between p53 mutations and inducible nitric oxide synthase expression in human colorectal cancer. J Natl Cancer Inst 91:86-88
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 86-88
-
-
Ambs, S.1
Bennett, W.P.2
Merriam, W.G.3
Ogunfusika, M.O.4
Oser, S.M.5
Harrington, A.M.6
Shields, P.G.7
Felley-Bosco, E.8
Hussain, S.P.9
Harris, C.C.10
-
5
-
-
0028181446
-
Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine
-
Bentivegna SS, Bresnick E (1994) Inhibition of human O6-methylguanine-DNA methyltransferase by 5-methylcytosine. Cancer Res 54:327-329
-
(1994)
Cancer Res
, vol.54
, pp. 327-329
-
-
Bentivegna, S.S.1
Bresnick, E.2
-
6
-
-
0031879857
-
Efficient repair of all types of single-base mismatches in recombination intermediates in Chinese hamster ovary cells: Competition between long-patch and G-T glycosylase-mediated repair of G-T mismatches
-
Bill CA, Duran WA, Miselis NR, Nickoloff JA (1998) Efficient repair of all types of single-base mismatches in recombination intermediates in Chinese hamster ovary cells: competition between long-patch and G-T glycosylase-mediated repair of G-T mismatches. Genetics 149:1935-1943
-
(1998)
Genetics
, vol.149
, pp. 1935-1943
-
-
Bill, C.A.1
Duran, W.A.2
Miselis, N.R.3
Nickoloff, J.A.4
-
7
-
-
0035300497
-
Unusual profile and high prevalence of p53 mutations in esophageal squamous cell carcinomas from northern Iran
-
Biramijamal F, Allameh A, Mirbod P, Groene HJ, Koomagi R, Hollstein M (2001) Unusual profile and high prevalence of p53 mutations in esophageal squamous cell carcinomas from northern Iran. Cancer Res 61:3119-3123
-
(2001)
Cancer Res
, vol.61
, pp. 3119-3123
-
-
Biramijamal, F.1
Allameh, A.2
Mirbod, P.3
Groene, H.J.4
Koomagi, R.5
Hollstein, M.6
-
8
-
-
0038119669
-
Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: Implications for the treatment of low-grade adult and pediatric brain tumors
-
Bodell WJ, Gaikwad NW, Miller D, Berger MS (2003) Formation of DNA adducts and induction of lacI mutations in Big Blue Rat-2 cells treated with temozolomide: implications for the treatment of low-grade adult and pediatric brain tumors. Cancer Epidemiol Biomarkers Prev 12:545-551
-
(2003)
Cancer Epidemiol Biomarkers Prev
, vol.12
, pp. 545-551
-
-
Bodell, W.J.1
Gaikwad, N.W.2
Miller, D.3
Berger, M.S.4
-
9
-
-
0035834708
-
Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1
-
Boorstein RJ, Cummings A Jr, Marenstein DR, Chan MK, Ma Y, Neubert TA, Brown SM, Teebor GW (2001) Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1. J Biol Chem 276:41991-41997
-
(2001)
J Biol Chem
, vol.276
, pp. 41991-41997
-
-
Boorstein, R.J.1
Cummings Jr., A.2
Marenstein, D.R.3
Chan, M.K.4
Ma, Y.5
Neubert, T.A.6
Brown, S.M.7
Teebor, G.W.8
-
10
-
-
0025719491
-
A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma
-
Brash DE, Rudolph JA, Simon JA, Lin A, McKenna GJ, Baden HP, Halperin AJ, Pontén J (1991) A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc Natl Acad Sci USA 88:10124-10128
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 10124-10128
-
-
Brash, D.E.1
Rudolph, J.A.2
Simon, J.A.3
Lin, A.4
McKenna, G.J.5
Baden, H.P.6
Halperin, A.J.7
Pontén, J.8
-
11
-
-
0037106658
-
Synthesis of stable-isotope enriched 5-methylpyrimidines and their use as probes of base reactivity in DNA
-
Burdzy A, Noyes KT, Valinluck V, Sowers LC (2002) Synthesis of stable-isotope enriched 5-methylpyrimidines and their use as probes of base reactivity in DNA. Nucleic Acids Res 30:4068-4074
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 4068-4074
-
-
Burdzy, A.1
Noyes, K.T.2
Valinluck, V.3
Sowers, L.C.4
-
12
-
-
0032523812
-
Carcinogens preferentially bind at methylated CpG in the p53 mutational hotspots
-
Chen JX, Zheng Y, West M, Tang M-s (1998) Carcinogens preferentially bind at methylated CpG in the p53 mutational hotspots. Cancer Res 58:2070-2075
-
(1998)
Cancer Res
, vol.58
, pp. 2070-2075
-
-
Chen, J.X.1
Zheng, Y.2
West, M.3
Tang, M.-S.4
-
13
-
-
0025152226
-
Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (±)-7b,8a-dihydroxy-9a,10a-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene
-
Chen R-H, Maher VM, McCormick JJ (1990) Effect of excision repair by diploid human fibroblasts on the kinds and locations of mutations induced by (±)-7b,8a-dihydroxy-9a,10a-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the HPRT gene. Proc Natl Acad Sci USA 87:8680-8684
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 8680-8684
-
-
Chen, R.-H.1
Maher, V.M.2
McCormick, J.J.3
-
14
-
-
0018185292
-
Molecular basis of base substitution hotspots in Escherichia coli
-
Coulondre C, Miller JH, Farabaugh PJ, Gilbert W (1978) Molecular basis of base substitution hotspots in Escherichia coli. Nature 274:775-780
-
(1978)
Nature
, vol.274
, pp. 775-780
-
-
Coulondre, C.1
Miller, J.H.2
Farabaugh, P.J.3
Gilbert, W.4
-
15
-
-
0029806936
-
Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53
-
Denissenko MF, Pao A, Tang M-s, Pfeifer GP (1996) Preferential formation of benzo[a]pyrene adducts at lung cancer mutational hotspots in P53. Science 274:430-432
-
(1996)
Science
, vol.274
, pp. 430-432
-
-
Denissenko, M.F.1
Pao, A.2
Tang, M.-S.3
Pfeifer, G.P.4
-
17
-
-
0032510267
-
Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers
-
Denissenko MF, Pao A, Pfeifer GP, Tang M-s (1998a) Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers. Oncogene 16:1241-1247
-
(1998)
Oncogene
, vol.16
, pp. 1241-1247
-
-
Denissenko, M.F.1
Pao, A.2
Pfeifer, G.P.3
Tang, M.-S.4
-
18
-
-
0037026482
-
Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase
-
Di Noia J, Neuberger MS (2002) Altering the pathway of immunoglobulin hypermutation by inhibiting uracil-DNA glycosylase. Nature 419:43-48
-
(2002)
Nature
, vol.419
, pp. 43-48
-
-
Di Noia, J.1
Neuberger, M.S.2
-
19
-
-
0031267083
-
UVB-induced cyclobutane pyrimidine dimer frequency correlates with skin cancer mutational hotspots in p53
-
Drouin R, Therrien J-P (1997) UVB-induced cyclobutane pyrimidine dimer frequency correlates with skin cancer mutational hotspots in p53. Photochem Photobiol 66:719-726
-
(1997)
Photochem Photobiol
, vol.66
, pp. 719-726
-
-
Drouin, R.1
Therrien, J.-P.2
-
20
-
-
0027379357
-
Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients
-
Dumaz N, Drougard C, Sarasin A, Daya-Grosjean L (1993) Specific UV-induced mutation spectrum in the p53 gene of skin tumors from DNA-repair-deficient xeroderma pigmentosum patients. Proc Natl Acad Sci USA 90:10529-10533
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 10529-10533
-
-
Dumaz, N.1
Drougard, C.2
Sarasin, A.3
Daya-Grosjean, L.4
-
21
-
-
0019198357
-
Mutagenic deamination of cytosine residues in DNA
-
Duncan BK, Miller JH (1980) Mutagenic deamination of cytosine residues in DNA. Nature 287:560-561
-
(1980)
Nature
, vol.287
, pp. 560-561
-
-
Duncan, B.K.1
Miller, J.H.2
-
22
-
-
0022648672
-
DNA cytosine methylation and heat-induced deamination
-
Ehrlich M, Norris KF, Wang RY, Kuo KC, Gehrke CW (1986) DNA cytosine methylation and heat-induced deamination. Biosci Rep 6:387-393
-
(1986)
Biosci Rep
, vol.6
, pp. 387-393
-
-
Ehrlich, M.1
Norris, K.F.2
Wang, R.Y.3
Kuo, K.C.4
Gehrke, C.W.5
-
23
-
-
0025268279
-
Spontaneous deamination of cytosine and 5-methylcytosine residues in DNA and replacement of 5-methylcytosine residues with cytosine residues
-
Ehrlich M, Zhang X-Y, Inamdar NM (1990) Spontaneous deamination of cytosine and 5-methylcytosine residues in DNA and replacement of 5-methylcytosine residues with cytosine residues. Mutat Res 238:277-286
-
(1990)
Mutat Res
, vol.238
, pp. 277-286
-
-
Ehrlich, M.1
Zhang, X.-Y.2
Inamdar, N.M.3
-
24
-
-
0026317881
-
High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer
-
El-Deiry WS, Nelkin BD, Celano P, Yen RW, Falco JP, Hamilton SR, Baylin SB (1991) High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer. Proc Natl Acad Sci USA 88:3470-3474
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3470-3474
-
-
El-Deiry, W.S.1
Nelkin, B.D.2
Celano, P.3
Yen, R.W.4
Falco, J.P.5
Hamilton, S.R.6
Baylin, S.B.7
-
25
-
-
0029163541
-
Nitric oxide and ethylnitrosourea: Relative mutagenicity in the p53 tumor suppressor and hypoxanthine-phosphoribosyltransferase genes
-
Felley-Bosco E, Mirkovitch J, Ambs S, Mace K, Pfeifer A, Keefer LK, Harris CC (1995) Nitric oxide and ethylnitrosourea: relative mutagenicity in the p53 tumor suppressor and hypoxanthine-phosphoribosyltransferase genes. Carcinogenesis 16:2069-2074
-
(1995)
Carcinogenesis
, vol.16
, pp. 2069-2074
-
-
Felley-Bosco, E.1
Mirkovitch, J.2
Ambs, S.3
Mace, K.4
Pfeifer, A.5
Keefer, L.K.6
Harris, C.C.7
-
26
-
-
0037020269
-
Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides
-
Fischhaber PL, Gerlach VL, Feaver WJ, Hatahet Z, Wallace SS, Friedberg EC (2002) Human DNA polymerase kappa bypasses and extends beyond thymine glycols during translesion synthesis in vitro, preferentially incorporating correct nucleotides. J Biol Chem 277:37604-37611
-
(2002)
J Biol Chem
, vol.277
, pp. 37604-37611
-
-
Fischhaber, P.L.1
Gerlach, V.L.2
Feaver, W.J.3
Hatahet, Z.4
Wallace, S.S.5
Friedberg, E.C.6
-
27
-
-
0025344222
-
A sensitive genetic assay for the detection of cytosine deamination: Determination of rate constants and the activation energy
-
Frederico LA, Kunkel TA, Shaw BR (1990) A sensitive genetic assay for the detection of cytosine deamination: determination of rate constants and the activation energy. Biochemistry 29:2532-2537
-
(1990)
Biochemistry
, vol.29
, pp. 2532-2537
-
-
Frederico, L.A.1
Kunkel, T.A.2
Shaw, B.R.3
-
29
-
-
0023754275
-
Base-sequence dependence of noncovalent complex formation and reactivity of benzo[a]pyrene diol epoxide with polynucleotides
-
Geacintov NE, Shabaz M, Ibanez V, Moussaoui K, harvey RG (1988) Base-sequence dependence of noncovalent complex formation and reactivity of benzo[a]pyrene diol epoxide with polynucleotides. Biochemistry 27:8380-8387
-
(1988)
Biochemistry
, vol.27
, pp. 8380-8387
-
-
Geacintov, N.E.1
Shabaz, M.2
Ibanez, V.3
Moussaoui, K.4
Harvey, R.G.5
-
30
-
-
0030902720
-
Mutagenic and epigenetic effects of DNA methylation
-
Gonzalgo ML, Jones PA (1997) Mutagenic and epigenetic effects of DNA methylation. Mutat Res 386:107-118
-
(1997)
Mutat Res
, vol.386
, pp. 107-118
-
-
Gonzalgo, M.L.1
Jones, P.A.2
-
31
-
-
0028071555
-
Mutations in the p53 tumor suppressor gene: Clues to cancer etiology and molecular pathogenesis
-
Greenblatt MS, Bennett WP, Hollstein M, Harris CC (1994) Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesis. Cancer Res 54:4855-4878
-
(1994)
Cancer Res
, vol.54
, pp. 4855-4878
-
-
Greenblatt, M.S.1
Bennett, W.P.2
Hollstein, M.3
Harris, C.C.4
-
32
-
-
0035171991
-
TP53 mutation spectrum in lung cancers and mutagenic signature of components of tobacco smoke: Lessons from the IARC TP53 mutation database
-
author reply 555-556
-
Hainaut P, Olivier M, Pfeifer GP (2001) TP53 mutation spectrum in lung cancers and mutagenic signature of components of tobacco smoke: lessons from the IARC TP53 mutation database. Mutagenesis 16:551-553; author reply 555-556
-
(2001)
Mutagenesis
, vol.16
, pp. 551-553
-
-
Hainaut, P.1
Olivier, M.2
Pfeifer, G.P.3
-
33
-
-
0037093739
-
Effect of diet on cancer development: Is oxidative DNA damage a biomarker?
-
Halliwell B (2002) Effect of diet on cancer development: is oxidative DNA damage a biomarker? Free Radic Biol Med 32:968-974
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 968-974
-
-
Halliwell, B.1
-
34
-
-
0032506037
-
A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch
-
Hang B, Medina M, Fraenkel-Conrat H, Singer B (1998) A 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatch. Proc Natl Acad Sci USA 95:13561-13566
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 13561-13566
-
-
Hang, B.1
Medina, M.2
Fraenkel-Conrat, H.3
Singer, B.4
-
35
-
-
0038074420
-
The versatile thymine DNA-glycosylase: A comparative characterization of the human, Drosophila and fission yeast orthologs
-
Hardeland U, Bentele M, Jiricny J, Schar P (2003) The versatile thymine DNA-glycosylase: a comparative characterization of the human, Drosophila and fission yeast orthologs. Nucleic Acids Res 31:2261-2271
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2261-2271
-
-
Hardeland, U.1
Bentele, M.2
Jiricny, J.3
Schar, P.4
-
36
-
-
0036863733
-
RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators
-
Harris RS, Petersen-Mahrt SK, Neuberger MS (2002) RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators. Mol Cell 10:1247-1253
-
(2002)
Mol Cell
, vol.10
, pp. 1247-1253
-
-
Harris, R.S.1
Petersen-Mahrt, S.K.2
Neuberger, M.S.3
-
37
-
-
0033602148
-
Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors
-
Haushalter KA, Todd Stukenberg MW, Kirschner MW, Verdine GL (1999) Identification of a new uracil-DNA glycosylase family by expression cloning using synthetic inhibitors. Curr Biol 9:174-185
-
(1999)
Curr Biol
, vol.9
, pp. 174-185
-
-
Haushalter, K.A.1
Todd Stukenberg, M.W.2
Kirschner, M.W.3
Verdine, G.L.4
-
38
-
-
0033591845
-
Tobacco smoke carcinogens and lung cancer
-
Hecht SS (1999) Tobacco smoke carcinogens and lung cancer. J Natl Cancer Inst 91:1194-1210
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 1194-1210
-
-
Hecht, S.S.1
-
39
-
-
0033575886
-
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
-
Hendrich B, Hardeland U, Ng H-H, Jiricny J, Bird A (1999) The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites. Nature 401:301-304
-
(1999)
Nature
, vol.401
, pp. 301-304
-
-
Hendrich, B.1
Hardeland, U.2
Ng, H.-H.3
Jiricny, J.4
Bird, A.5
-
40
-
-
0026094872
-
The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease
-
Hennecke F, Kolmar H, Brundl K, Fritz HJ (1991) The vsr gene product of E. coli K-12 is a strand- and sequence-specific DNA mismatch endonuclease. Nature 353:776-778
-
(1991)
Nature
, vol.353
, pp. 776-778
-
-
Hennecke, F.1
Kolmar, H.2
Brundl, K.3
Fritz, H.J.4
-
41
-
-
0031758362
-
A specific spectrum of p53 mutations in lung cancer from smokers: Review of mutations compiled in the IARC p53 database
-
Hernandez-Boussard TM, Hainaut P (1998) A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database. Environ Health Perspect 106:385-391
-
(1998)
Environ Health Perspect
, vol.106
, pp. 385-391
-
-
Hernandez-Boussard, T.M.1
Hainaut, P.2
-
43
-
-
0032565509
-
Endogenous lesions, S-phase-independent spontaneous mutations, and evolutionary strategies for base excision repair
-
Holmquist GP (1998) Endogenous lesions, S-phase-independent spontaneous mutations, and evolutionary strategies for base excision repair. Mutat Res 400:59-68
-
(1998)
Mutat Res
, vol.400
, pp. 59-68
-
-
Holmquist, G.P.1
-
44
-
-
0032530215
-
Molecular epidemiology of human cancer: Contribution of mutation spectra studies of tumor suppressor genes
-
Hussain SP, Harris CC (1998) Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. Cancer Res 58:4023-4037
-
(1998)
Cancer Res
, vol.58
, pp. 4023-4037
-
-
Hussain, S.P.1
Harris, C.C.2
-
45
-
-
0346606862
-
Increased p53 mutation load in non-cancerous colon tissue from ulcerative colitis: A cancer-prone chronic inflammatory disease
-
Hussain SP, Amstad P, Raja K, Ambs S, Nagashima M, Bennett WP, Shields PG, Ham AJ, Swenberg JA, Marrogi AJ, Harris CC (2000) Increased p53 mutation load in non-cancerous colon tissue from ulcerative colitis: a cancer-prone chronic inflammatory disease. Cancer Res 60:3333-3337
-
(2000)
Cancer Res
, vol.60
, pp. 3333-3337
-
-
Hussain, S.P.1
Amstad, P.2
Raja, K.3
Ambs, S.4
Nagashima, M.5
Bennett, W.P.6
Shields, P.G.7
Ham, A.J.8
Swenberg, J.A.9
Marrogi, A.J.10
Harris, C.C.11
-
46
-
-
0035796023
-
The contribution of endogenous sources of DNA damage to the multiple mutations in cancer
-
Jackson AL, Loeb LA (2001) The contribution of endogenous sources of DNA damage to the multiple mutations in cancer. Mutat Res 477:7-21
-
(2001)
Mutat Res
, vol.477
, pp. 7-21
-
-
Jackson, A.L.1
Loeb, L.A.2
-
47
-
-
0037226587
-
Yeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycol
-
Johnson RE, Yu SL, Prakash S, Prakash L (2003) Yeast DNA polymerase zeta (zeta) is essential for error-free replication past thymine glycol. Genes Dev 17:77-87
-
(2003)
Genes Dev
, vol.17
, pp. 77-87
-
-
Johnson, R.E.1
Yu, S.L.2
Prakash, S.3
Prakash, L.4
-
48
-
-
0030459428
-
Frequent clones of p53-mutated keratinocytes in normal human skin
-
Jonason AS, Kunala S, Price GJ, Restifo RJ, Spinelli HM, Persing JA, Leffell DJ, Tarone RE, Brash DE (1996) Frequent clones of p53-mutated keratinocytes in normal human skin. Proc Natl Acad Sci USA 93:14025-14029
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 14025-14029
-
-
Jonason, A.S.1
Kunala, S.2
Price, G.J.3
Restifo, R.J.4
Spinelli, H.M.5
Persing, J.A.6
Leffell, D.J.7
Tarone, R.E.8
Brash, D.E.9
-
49
-
-
0029898837
-
DNA methylation errors and cancer
-
Jones PA (1996) DNA methylation errors and cancer. Cancer Res 56:2463-2467
-
(1996)
Cancer Res
, vol.56
, pp. 2463-2467
-
-
Jones, P.A.1
-
50
-
-
0036274359
-
The fundamental role of epigenetic events in cancer
-
Jones PA, Baylin SB (2002) The fundamental role of epigenetic events in cancer. Nat Rev Genet 3:415-428
-
(2002)
Nat Rev Genet
, vol.3
, pp. 415-428
-
-
Jones, P.A.1
Baylin, S.B.2
-
51
-
-
0026443296
-
Methylation, mutation and cancer
-
Jones PA, Rideout WM, Shen J-C, Spruck CH, Tsai YC (1992) Methylation, mutation and cancer. BioEssays 14:33-36
-
(1992)
BioEssays
, vol.14
, pp. 33-36
-
-
Jones, P.A.1
Rideout, W.M.2
Shen, J.-C.3
Spruck, C.H.4
Tsai, Y.C.5
-
52
-
-
0035863859
-
Induction of T ->G and T ->A transversions by 5-formyluracil in mammalian cells
-
Kamiya H, Murata-Kamiya N, Karino N, Ueno Y, Matsuda A, Kasai H (2002a) Induction of T ->G and T ->A transversions by 5-formyluracil in mammalian cells. Mutat Res 513:213-222
-
(2002)
Mutat Res
, vol.513
, pp. 213-222
-
-
Kamiya, H.1
Murata-Kamiya, N.2
Karino, N.3
Ueno, Y.4
Matsuda, A.5
Kasai, H.6
-
53
-
-
0036773784
-
Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells
-
Kamiya H, Tsuchiya H, Karino N, Ueno Y, Matsuda A, Harashima H (2002b) Mutagenicity of 5-formylcytosine, an oxidation product of 5-methylcytosine, in DNA in mammalian cells. J Biochem (Tokyo) 132:551-555
-
(2002)
J Biochem (Tokyo)
, vol.132
, pp. 551-555
-
-
Kamiya, H.1
Tsuchiya, H.2
Karino, N.3
Ueno, Y.4
Matsuda, A.5
Harashima, H.6
-
54
-
-
0031657569
-
DNA modifications by the mutagen glyoxal: Adduction to G and C, deamination of C and GC and GA cross-linking
-
Kasai H, Iwamoto-Tanaka N, Fukada S (1998) DNA modifications by the mutagen glyoxal: adduction to G and C, deamination of C and GC and GA cross-linking. Carcinogenesis 19:1459-1465
-
(1998)
Carcinogenesis
, vol.19
, pp. 1459-1465
-
-
Kasai, H.1
Iwamoto-Tanaka, N.2
Fukada, S.3
-
55
-
-
18644363009
-
UNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup
-
Kavli B, Sundheim O, Akbari M, Otterlei M, Nilsen H, Skorpen F, Aas PA, Hagen L, Krokan HE, Slupphaug G (2002) hUNG2 is the major repair enzyme for removal of uracil from U:A matches, U:G mismatches, and U in single-stranded DNA, with hSMUG1 as a broad specificity backup. J Biol Chem 277:39926-39936
-
(2002)
J Biol Chem
, vol.277
, pp. 39926-39936
-
-
Kavli, B.1
Sundheim, O.2
Akbari, M.3
Otterlei, M.4
Nilsen, H.5
Skorpen, F.6
Aas, P.A.7
Hagen, L.8
Krokan, H.E.9
Slupphaug, G.10
-
56
-
-
0028010888
-
HhaI methyltransferase flips its target base out of the DNA helix
-
Klimasauskas S, Kumar S, Roberts RJ, Cheng X (1994) HhaI methyltransferase flips its target base out of the DNA helix. Cell 76:357-369
-
(1994)
Cell
, vol.76
, pp. 357-369
-
-
Klimasauskas, S.1
Kumar, S.2
Roberts, R.J.3
Cheng, X.4
-
57
-
-
0028150623
-
Spontaneous mutations in lacI-containing lambda lysogens derived from transgenic mice: The observed patterns differ in liver and spleen
-
Knoll A, Jacobson DP, Kretz PL, Lundberg KS, Short JM, Sommer SS (1994) Spontaneous mutations in lacI-containing lambda lysogens derived from transgenic mice: the observed patterns differ in liver and spleen. Mutat Res 311:57-67
-
(1994)
Mutat Res
, vol.311
, pp. 57-67
-
-
Knoll, A.1
Jacobson, D.P.2
Kretz, P.L.3
Lundberg, K.S.4
Short, J.M.5
Sommer, S.S.6
-
58
-
-
0032231701
-
Neighboring-nucleotide effects on the rates of germ-line single-base-pair substitution in human genes
-
Krawczak M, Ball EV, Cooper DN (1998) Neighboring-nucleotide effects on the rates of germ-line single-base-pair substitution in human genes. Am J Hum Genet 63:474-488
-
(1998)
Am J Hum Genet
, vol.63
, pp. 474-488
-
-
Krawczak, M.1
Ball, E.V.2
Cooper, D.N.3
-
59
-
-
0037115911
-
Uracil in DNA-occurrence, consequences and repair
-
Krokan HE, Drablos F, Slupphaug G (2002) Uracil in DNA-occurrence, consequences and repair. Oncogene 21:8935-8948
-
(2002)
Oncogene
, vol.21
, pp. 8935-8948
-
-
Krokan, H.E.1
Drablos, F.2
Slupphaug, G.3
-
60
-
-
0037076519
-
Translesion synthesis by human DNA polymerase eta across thymine glycol lesions
-
Kusumoto R, Masutani C, Iwai S, Hanaoka F (2002) Translesion synthesis by human DNA polymerase eta across thymine glycol lesions. Biochemistry 41:6090-6099
-
(2002)
Biochemistry
, vol.41
, pp. 6090-6099
-
-
Kusumoto, R.1
Masutani, C.2
Iwai, S.3
Hanaoka, F.4
-
61
-
-
0030459140
-
The role of DNA methylation in cancer genetics and epigenetics
-
Laird PW, Jaenisch R (1996) The role of DNA methylation in cancer genetics and epigenetics. Annu Rev Genet 30:441-464
-
(1996)
Annu Rev Genet
, vol.30
, pp. 441-464
-
-
Laird, P.W.1
Jaenisch, R.2
-
62
-
-
10644229388
-
Methylation protects cytidines from AID-mediated deamination
-
Larijani M, Frieder D, Sonbuchner TM, Bransteitter R, Goodman MF, Bouhassira EE, Scharff MD, Martin A (2005) Methylation protects cytidines from AID-mediated deamination. Mol Immunol 42:599-604
-
(2005)
Mol Immunol
, vol.42
, pp. 599-604
-
-
Larijani, M.1
Frieder, D.2
Sonbuchner, T.M.3
Bransteitter, R.4
Goodman, M.F.5
Bouhassira, E.E.6
Scharff, M.D.7
Martin, A.8
-
63
-
-
0038193611
-
Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis
-
Lee DH, Pfeifer GP (2003) Deamination of 5-methylcytosines within cyclobutane pyrimidine dimers is an important component of UVB mutagenesis. J Biol Chem 278:10314-10321
-
(2003)
J Biol Chem
, vol.278
, pp. 10314-10321
-
-
Lee, D.H.1
Pfeifer, G.P.2
-
64
-
-
0037102626
-
Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells
-
Lee DH, O'Connor TR, Pfeifer GP (2002) Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells. Nucleic Acids Res 30:3566-3573
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 3566-3573
-
-
Lee, D.H.1
O'Connor, T.R.2
Pfeifer, G.P.3
-
65
-
-
0026773508
-
In vitro reaction of ethylene oxide with DNA and characterization of DNA adducts
-
Li F, Segal A, Solomon JJ (1992) In vitro reaction of ethylene oxide with DNA and characterization of DNA adducts. Chem Biol Interact 83:35-54
-
(1992)
Chem Biol Interact
, vol.83
, pp. 35-54
-
-
Li, F.1
Segal, A.2
Solomon, J.J.3
-
66
-
-
0025754787
-
Spontaneous mutation at a 5-methylcytosine hotspot is prevented by very short patch (VSP) mismatch repair
-
Lieb M (1991) Spontaneous mutation at a 5-methylcytosine hotspot is prevented by very short patch (VSP) mismatch repair. Genetics 128:23-27
-
(1991)
Genetics
, vol.128
, pp. 23-27
-
-
Lieb, M.1
-
67
-
-
0027278557
-
Instability and decay of the primary structure of DNA
-
Lindahl T (1993) Instability and decay of the primary structure of DNA. Nature 362:709-715
-
(1993)
Nature
, vol.362
, pp. 709-715
-
-
Lindahl, T.1
-
68
-
-
0028007418
-
Reductive metabolism of 1-nitropyrene accompanies deamination of cytosine
-
Malia SA, Basu AK (1994) Reductive metabolism of 1-nitropyrene accompanies deamination of cytosine. Chem Res Toxicol 7:823-828
-
(1994)
Chem Res Toxicol
, vol.7
, pp. 823-828
-
-
Malia, S.A.1
Basu, A.K.2
-
69
-
-
0027493111
-
Endogenous DNA adducts: Potential and paradox
-
Marnett LJ, Burcham PC (1993) Endogenous DNA adducts: potential and paradox. Chem Res Toxicol 6:771-785
-
(1993)
Chem Res Toxicol
, vol.6
, pp. 771-785
-
-
Marnett, L.J.1
Burcham, P.C.2
-
70
-
-
0037135130
-
Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice
-
Millar CB, Guy J, Sansom OJ, Selfridge J, MacDougall E, Hendrich B, Keightley PD, Bishop SM, Clarke AR, Bird A (2002) Enhanced CpG mutability and tumorigenesis in MBD4-deficient mice. Science 297:403-405
-
(2002)
Science
, vol.297
, pp. 403-405
-
-
Millar, C.B.1
Guy, J.2
Sansom, O.J.3
Selfridge, J.4
MacDougall, E.5
Hendrich, B.6
Keightley, P.D.7
Bishop, S.M.8
Clarke, A.R.9
Bird, A.10
-
71
-
-
10644282845
-
Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: Implications for epigenetic reprogramming
-
Morgan HD, Dean W, Coker HA, Reik W, Petersen-Mahrt SK (2004) Activation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogramming. J Biol Chem 279:52353-52360
-
(2004)
J Biol Chem
, vol.279
, pp. 52353-52360
-
-
Morgan, H.D.1
Dean, W.2
Coker, H.A.3
Reik, W.4
Petersen-Mahrt, S.K.5
-
72
-
-
0025904357
-
Squamous cell and basal cell skin carcinoma and rarer histologic types of skin cancer
-
Mortimer P (1991) Squamous cell and basal cell skin carcinoma and rarer histologic types of skin cancer. Curr Opin Oncol 3:349-354
-
(1991)
Curr Opin Oncol
, vol.3
, pp. 349-354
-
-
Mortimer, P.1
-
73
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M, Kinoshita K, Fagarasan S, Yamada S, Shinkai Y, Honjo T (2000) Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 102:553-563
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
74
-
-
15844419144
-
Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase
-
Neddermann P, Gallinari P, Lettieri T, Schmid D, Truong O, Hsuan JJ, Wiebauer K, Jiricny J (1996) Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase. J Biol Chem 271:12767-12774
-
(1996)
J Biol Chem
, vol.271
, pp. 12767-12774
-
-
Neddermann, P.1
Gallinari, P.2
Lettieri, T.3
Schmid, D.4
Truong, O.5
Hsuan, J.J.6
Wiebauer, K.7
Jiricny, J.8
-
75
-
-
0033636312
-
Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication
-
Nilsen H, Rosewell I, Robins P, Skjelbred CF, Andersen S, Slupphaug G, Daly G, Krokan HE, Lindahl T, Barnes DE (2000) Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication. Mol Cell 5:1059-1065
-
(2000)
Mol Cell
, vol.5
, pp. 1059-1065
-
-
Nilsen, H.1
Rosewell, I.2
Robins, P.3
Skjelbred, C.F.4
Andersen, S.5
Slupphaug, G.6
Daly, G.7
Krokan, H.E.8
Lindahl, T.9
Barnes, D.E.10
-
76
-
-
0035421186
-
Excision of deaminated cytosine from the vertebrate genome: Role of the SMUG1 uracil-DNA glycosylase
-
Nilsen H, Haushalter KA, Robins P, Barnes DE, Verdine GL, Lindahl T (2001) Excision of deaminated cytosine from the vertebrate genome: role of the SMUG1 uracil-DNA glycosylase. EMBO J 20:4278-4286
-
(2001)
EMBO J
, vol.20
, pp. 4278-4286
-
-
Nilsen, H.1
Haushalter, K.A.2
Robins, P.3
Barnes, D.E.4
Verdine, G.L.5
Lindahl, T.6
-
77
-
-
0031668970
-
Transition mutations at CpG dinucleotides are the most frequent in vivo spontaneous single-base substitution mutation in the human HPRT gene
-
O'Neill JP, Finette BA (1998) Transition mutations at CpG dinucleotides are the most frequent in vivo spontaneous single-base substitution mutation in the human HPRT gene. Environ Mol Mutagen 32:188-191
-
(1998)
Environ Mol Mutagen
, vol.32
, pp. 188-191
-
-
O'Neill, J.P.1
Finette, B.A.2
-
78
-
-
0036258111
-
The IARC TP53 database: New online mutation analysis and recommendations to users
-
Olivier M, Eeles R, Hollstein M, Khan MA, Harris CC, Hainaut P (2002) The IARC TP53 database: new online mutation analysis and recommendations to users. Hum Mutat 19:607-614
-
(2002)
Hum Mutat
, vol.19
, pp. 607-614
-
-
Olivier, M.1
Eeles, R.2
Hollstein, M.3
Khan, M.A.4
Harris, C.C.5
Hainaut, P.6
-
79
-
-
0024414264
-
Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme
-
Olsen LC, Aasland R, Wittwer CU, Krokan HE, Helland DE (1989) Molecular cloning of human uracil-DNA glycosylase, a highly conserved DNA repair enzyme. EMBO J 8:3121-3125
-
(1989)
EMBO J
, vol.8
, pp. 3121-3125
-
-
Olsen, L.C.1
Aasland, R.2
Wittwer, C.U.3
Krokan, H.E.4
Helland, D.E.5
-
80
-
-
2442502616
-
A molecular understanding of mitoxantrone-DNA adduct formation: Effect of cytosine methylation and flanking sequences
-
Parker BS, Buley T, Evison BJ, Cutts SM, Neumann GM, Iskander MN, Phillips DR (2004) A molecular understanding of mitoxantrone-DNA adduct formation: effect of cytosine methylation and flanking sequences. J Biol Chem 279:18814-18823
-
(2004)
J Biol Chem
, vol.279
, pp. 18814-18823
-
-
Parker, B.S.1
Buley, T.2
Evison, B.J.3
Cutts, S.M.4
Neumann, G.M.5
Iskander, M.N.6
Phillips, D.R.7
-
81
-
-
0037019315
-
AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification
-
Petersen-Mahrt SK, Harris RS, Neuberger MS (2002) AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification. Nature 418:99-103
-
(2002)
Nature
, vol.418
, pp. 99-103
-
-
Petersen-Mahrt, S.K.1
Harris, R.S.2
Neuberger, M.S.3
-
82
-
-
0031080462
-
Formation and processing of UV photoproducts: Effects of DNA sequence and chromatin environment
-
Pfeifer GP (1997) Formation and processing of UV photoproducts: effects of DNA sequence and chromatin environment. Photochem Photobiol 65:270-283
-
(1997)
Photochem Photobiol
, vol.65
, pp. 270-283
-
-
Pfeifer, G.P.1
-
83
-
-
0034732883
-
P53 mutational spectra and the role of methylated CpG sequences
-
Pfeifer GP (2000) p53 mutational spectra and the role of methylated CpG sequences. Mutat Res 450:155-166
-
(2000)
Mutat Res
, vol.450
, pp. 155-166
-
-
Pfeifer, G.P.1
-
84
-
-
0026071587
-
In vivo mapping of a DNA adduct at nucleotide resolution: Detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reaction
-
Pfeifer GP, Drouin R, Riggs AD, Holmquist GP (1991) In vivo mapping of a DNA adduct at nucleotide resolution: detection of pyrimidine (6-4) pyrimidone photoproducts by ligation-mediated polymerase chain reaction. Proc Natl Acad Sci USA 88:1374-1378
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 1374-1378
-
-
Pfeifer, G.P.1
Drouin, R.2
Riggs, A.D.3
Holmquist, G.P.4
-
85
-
-
0037152628
-
Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers
-
Pfeifer GP, Denissenko MF, Olivier M, Tretyakova N, Hecht SS, Hainaut P (2002) Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers. Oncogene 21:7435-7451
-
(2002)
Oncogene
, vol.21
, pp. 7435-7451
-
-
Pfeifer, G.P.1
Denissenko, M.F.2
Olivier, M.3
Tretyakova, N.4
Hecht, S.S.5
Hainaut, P.6
-
86
-
-
0037926476
-
Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation
-
Pham P, Bransteitter R, Petruska J, Goodman MF (2003) Processive AID-catalysed cytosine deamination on single-stranded DNA simulates somatic hypermutation. Nature 424:103-107
-
(2003)
Nature
, vol.424
, pp. 103-107
-
-
Pham, P.1
Bransteitter, R.2
Petruska, J.3
Goodman, M.F.4
-
87
-
-
0029894026
-
Photochemical deamination and demethylation of 5-methylcytosine
-
Privat E, Sowers LC (1996) Photochemical deamination and demethylation of 5-methylcytosine. Chem Res Toxicol 9:745-750
-
(1996)
Chem Res Toxicol
, vol.9
, pp. 745-750
-
-
Privat, E.1
Sowers, L.C.2
-
88
-
-
0026356298
-
Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens
-
Puisieux A, Lim S, Groopman J, Ozturk M (1991) Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens. Cancer Res 51:6185-6189
-
(1991)
Cancer Res
, vol.51
, pp. 6185-6189
-
-
Puisieux, A.1
Lim, S.2
Groopman, J.3
Ozturk, M.4
-
89
-
-
0038293484
-
Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand
-
Ramiro AR, Stavropoulos P, Jankovic M, Nussenzweig MC (2003) Transcription enhances AID-mediated cytidine deamination by exposing single-stranded DNA on the nontemplate strand. Nat Immunol 4:452-456
-
(2003)
Nat Immunol
, vol.4
, pp. 452-456
-
-
Ramiro, A.R.1
Stavropoulos, P.2
Jankovic, M.3
Nussenzweig, M.C.4
-
90
-
-
0025145277
-
5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes
-
Rideout WM 3rd, Coetzee GA, Olumi AF, Jones PA (1990) 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. Science 249:1288-1290
-
(1990)
Science
, vol.249
, pp. 1288-1290
-
-
Rideout III, W.M.1
Coetzee, G.A.2
Olumi, A.F.3
Jones, P.A.4
-
91
-
-
0020986251
-
5-Methylcytosine, gene regulation, and cancer
-
Riggs AD, Jones PA (1983) 5-Methylcytosine, gene regulation, and cancer. Adv Cancer Res 40:1-30
-
(1983)
Adv Cancer Res
, vol.40
, pp. 1-30
-
-
Riggs, A.D.1
Jones, P.A.2
-
92
-
-
0027500049
-
Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene
-
Ruggeri B, DiRado M, Zhang SY, Bauer B, Goodrow T, Klein-Szanto AJP (1993) Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene. Proc Natl Acad Sci USA 90:1013-1017
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 1013-1017
-
-
Ruggeri, B.1
Dirado, M.2
Zhang, S.Y.3
Bauer, B.4
Goodrow, T.5
Klein-Szanto, A.J.P.6
-
93
-
-
0034687768
-
An unexpectedly high excision capacity for mispaired 5- hydroxymethyluracil in human cell extracts
-
Rusmintratip V, Sowers LC (2000) An unexpectedly high excision capacity for mispaired 5-hydroxymethyluracil in human cell extracts. Proc Natl Acad Sci U S A 97:14183-14187
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 14183-14187
-
-
Rusmintratip, V.1
Sowers, L.C.2
-
95
-
-
0032555065
-
3,N4-Ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase
-
Saparbaev M, Laval J (1998) 3,N4-Ethenocytosine, a highly mutagenic adduct, is a primary substrate for Escherichia coli double-stranded uracil-DNA glycosylase and human mismatch-specific thymine-DNA glycosylase. Proc Natl Acad Sci USA 95:8508-8513
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8508-8513
-
-
Saparbaev, M.1
Laval, J.2
-
96
-
-
0031981810
-
Involvement of DNA methylation in human carcinogenesis
-
Schmutte C, Jones PA (1998) Involvement of DNA methylation in human carcinogenesis. Biol Chem 379:377-388
-
(1998)
Biol Chem
, vol.379
, pp. 377-388
-
-
Schmutte, C.1
Jones, P.A.2
-
97
-
-
0028598633
-
Mutagenicity of nitric oxide is not caused by deamination of cytosine or 5-methylcytosine in double-stranded DNA
-
Schmutte C, Rideout WM, Shen JC, Jones PA (1994) Mutagenicity of nitric oxide is not caused by deamination of cytosine or 5-methylcytosine in double-stranded DNA. Carcinogenesis 15:2899-2903
-
(1994)
Carcinogenesis
, vol.15
, pp. 2899-2903
-
-
Schmutte, C.1
Rideout, W.M.2
Shen, J.C.3
Jones, P.A.4
-
98
-
-
0029095974
-
Base excision repair of U:G mismatches at a mutational hotspot in the p53 gene is more efficient than base excision repair of T:G mismatches in extracts of human colon tumors
-
Schmutte C, Yang AS, Beart RW, Jones PA (1995) Base excision repair of U:G mismatches at a mutational hotspot in the p53 gene is more efficient than base excision repair of T:G mismatches in extracts of human colon tumors. Cancer Res 55:3742-3746
-
(1995)
Cancer Res
, vol.55
, pp. 3742-3746
-
-
Schmutte, C.1
Yang, A.S.2
Beart, R.W.3
Jones, P.A.4
-
99
-
-
0030009868
-
Mechanisms for the involvement of DNA methylation in colon carcinogenesis
-
Schmutte C, Yang AS, Nguyen TT, Beart RW, Jones PA (1996) Mechanisms for the involvement of DNA methylation in colon carcinogenesis. Cancer Res 56:2375-2381
-
(1996)
Cancer Res
, vol.56
, pp. 2375-2381
-
-
Schmutte, C.1
Yang, A.S.2
Nguyen, T.T.3
Beart, R.W.4
Jones, P.A.5
-
100
-
-
0026537668
-
Analysis of CpG suppression in methylated and nonmethylated species
-
Schorderet DF, Gartler SM (1992) Analysis of CpG suppression in methylated and nonmethylated species. Proc Natl Acad Sci USA 89:957-961
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 957-961
-
-
Schorderet, D.F.1
Gartler, S.M.2
-
101
-
-
0035504669
-
Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophagus in Iran
-
Sepehr A, Taniere P, Martel-Planche G, Zia'ee AA, Rastgar-Jazii F, Yazdanbod M, Etemad-Moghadam G, Kamangar F, Saidi F, Hainaut P (2001) Distinct pattern of TP53 mutations in squamous cell carcinoma of the esophagus in Iran. Oncogene 20:7368-7374
-
(2001)
Oncogene
, vol.20
, pp. 7368-7374
-
-
Sepehr, A.1
Taniere, P.2
Martel-Planche, G.3
Zia'Ee, A.A.4
Rastgar-Jazii, F.5
Yazdanbod, M.6
Etemad-Moghadam, G.7
Kamangar, F.8
Saidi, F.9
Hainaut, P.10
-
102
-
-
0027093283
-
High frequency mutagenesis by a DNA methyltransferase
-
Shen JC, Rideout WM, Jones PA (1992) High frequency mutagenesis by a DNA methyltransferase. Cell 71:1073-1080
-
(1992)
Cell
, vol.71
, pp. 1073-1080
-
-
Shen, J.C.1
Rideout, W.M.2
Jones, P.A.3
-
103
-
-
0028358421
-
The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA
-
Shen JC, Rideout WM 3rd, Jones PA (1994) The rate of hydrolytic deamination of 5-methylcytosine in double-stranded DNA. Nucleic Acids Res 22:972-976
-
(1994)
Nucleic Acids Res
, vol.22
, pp. 972-976
-
-
Shen, J.C.1
Rideout III, W.M.2
Jones, P.A.3
-
104
-
-
0025327968
-
A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene
-
Sohail A, Lieb M, Dar M, Bhagwat AS (1990) A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene. J Bacteriol 172:4214-4221
-
(1990)
J Bacteriol
, vol.172
, pp. 4214-4221
-
-
Sohail, A.1
Lieb, M.2
Dar, M.3
Bhagwat, A.S.4
-
105
-
-
0037901850
-
Human activation-induced cytidine deaminase causes transcription- dependent, strand-biased C to U deaminations
-
Sohail A, Klapacz J, Samaranayake M, Ullah A, Bhagwat AS (2003) Human activation-induced cytidine deaminase causes transcription-dependent, strand-biased C to U deaminations. Nucleic Acids Res 31:2990-2994
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 2990-2994
-
-
Sohail, A.1
Klapacz, J.2
Samaranayake, M.3
Ullah, A.4
Bhagwat, A.S.5
-
106
-
-
0028960841
-
Recent human germ-line mutation: Inferences from patients with hemophilia B
-
Sommer SS (1995) Recent human germ-line mutation: inferences from patients with hemophilia B. Trends Genet 11:141-147
-
(1995)
Trends Genet
, vol.11
, pp. 141-147
-
-
Sommer, S.S.1
-
107
-
-
0033982762
-
Transition mutation in codon 248 of the p53 tumor suppressor gene induced by reactive oxygen species and a nitric oxide-releasing compound
-
Souici AC, Mirkovitch J, Hausel P, Keefer LK, Felley-Bosco E (2000) Transition mutation in codon 248 of the p53 tumor suppressor gene induced by reactive oxygen species and a nitric oxide-releasing compound. Carcinogenesis 21:281-287
-
(2000)
Carcinogenesis
, vol.21
, pp. 281-287
-
-
Souici, A.C.1
Mirkovitch, J.2
Hausel, P.3
Keefer, L.K.4
Felley-Bosco, E.5
-
108
-
-
0023667625
-
Base stacking and molecular polarizability: Effect of a methyl group in the 5-position of pyrimidines
-
Sowers LC, Shaw BR, Sedwick WD (1987) Base stacking and molecular polarizability: effect of a methyl group in the 5-position of pyrimidines. Biochem Biophys Res Commun 148:790-794
-
(1987)
Biochem Biophys Res Commun
, vol.148
, pp. 790-794
-
-
Sowers, L.C.1
Shaw, B.R.2
Sedwick, W.D.3
-
109
-
-
0025299347
-
The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutational model
-
Sved J, Bird A (1990) The expected equilibrium of the CpG dinucleotide in vertebrate genomes under a mutational model. Proc Natl Acad Sci USA 87:4692-4696
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 4692-4696
-
-
Sved, J.1
Bird, A.2
-
110
-
-
0030859713
-
Sunlight induces pyrimidine dimers preferentially at 5-methylcytosine bases
-
Tommasi S, Denissenko MF, Pfeifer GP (1997) Sunlight induces pyrimidine dimers preferentially at 5-methylcytosine bases. Cancer Res 57:4727-4730
-
(1997)
Cancer Res
, vol.57
, pp. 4727-4730
-
-
Tommasi, S.1
Denissenko, M.F.2
Pfeifer, G.P.3
-
111
-
-
0028215974
-
Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer
-
Tornaletti S, Pfeifer GP (1994) Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer. Science 263:1436-1438
-
(1994)
Science
, vol.263
, pp. 1436-1438
-
-
Tornaletti, S.1
Pfeifer, G.P.2
-
112
-
-
0029027343
-
Complete and tissue-independent methylation of CpG sites in the p53 gene: Implications for mutations in human cancers
-
Tornaletti S, Pfeifer GP (1995) Complete and tissue-independent methylation of CpG sites in the p53 gene: implications for mutations in human cancers. Oncogene 10:1493-1499
-
(1995)
Oncogene
, vol.10
, pp. 1493-1499
-
-
Tornaletti, S.1
Pfeifer, G.P.2
-
113
-
-
0027292296
-
The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer
-
Tornaletti S, Rozek D, Pfeifer GP (1993) The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer. Oncogene 8:2051-2057
-
(1993)
Oncogene
, vol.8
, pp. 2051-2057
-
-
Tornaletti, S.1
Rozek, D.2
Pfeifer, G.P.3
-
114
-
-
0037199429
-
Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: Stable isotope-labeling mass spectrometry approach
-
Tretyakova N, Matter B, Jones R, Shallop A (2002) Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach. Biochemistry 41:9535-9544
-
(2002)
Biochemistry
, vol.41
, pp. 9535-9544
-
-
Tretyakova, N.1
Matter, B.2
Jones, R.3
Shallop, A.4
-
115
-
-
0032573433
-
Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo
-
Tu Y, Dammann R, Pfeifer GP (1998) Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo. J Mol Biol 284:297-311
-
(1998)
J Mol Biol
, vol.284
, pp. 297-311
-
-
Tu, Y.1
Dammann, R.2
Pfeifer, G.P.3
-
116
-
-
0019332015
-
Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues
-
Wang RY, Gehrke CW, Ehrlich M (1980) Comparison of bisulfite modification of 5-methyldeoxycytidine and deoxycytidine residues. Nucleic Acids Res 8:4777-4790
-
(1980)
Nucleic Acids Res
, vol.8
, pp. 4777-4790
-
-
Wang, R.Y.1
Gehrke, C.W.2
Ehrlich, M.3
-
117
-
-
0020493818
-
Heat- and alkali-induced deamination of 5-methylcytosine and cytosine residues in DNA
-
Wang RY, Kuo KC, Gehrke CW, Huang LH, Ehrlich M (1982) Heat- and alkali-induced deamination of 5-methylcytosine and cytosine residues in DNA. Biochim Biophys Acta 697:371-377
-
(1982)
Biochim Biophys Acta
, vol.697
, pp. 371-377
-
-
Wang, R.Y.1
Kuo, K.C.2
Gehrke, C.W.3
Huang, L.H.4
Ehrlich, M.5
-
118
-
-
0029071485
-
Mutations in the p53 gene in schistosomal bladder cancer: A study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours
-
Warren W, Biggs PJ, El-Baz M, Ghoneim MA, Stratton MR, Venitt S (1995) Mutations in the p53 gene in schistosomal bladder cancer: a study of 92 tumours from Egyptian patients and a comparison between mutational spectra from schistosomal and non-schistosomal urothelial tumours. Carcinogenesis 16:1181-1189
-
(1995)
Carcinogenesis
, vol.16
, pp. 1181-1189
-
-
Warren, W.1
Biggs, P.J.2
El-Baz, M.3
Ghoneim, M.A.4
Stratton, M.R.5
Venitt, S.6
-
119
-
-
0032493637
-
Kinetics of the action of thymine DNA glycosylase
-
Waters TR, Swann PF (1998) Kinetics of the action of thymine DNA glycosylase. J Biol Chem 273:20007-20014
-
(1998)
J Biol Chem
, vol.273
, pp. 20007-20014
-
-
Waters, T.R.1
Swann, P.F.2
-
120
-
-
0033588231
-
Cytosine methylation in a CpG sequence leads to enhanced reactivity with Benzo[a]pyrene diol epoxide that correlates with a conformational change
-
Weisenberger DJ, Romano LJ (1999) Cytosine methylation in a CpG sequence leads to enhanced reactivity with Benzo[a]pyrene diol epoxide that correlates with a conformational change. J Biol Chem 274:23948-23955
-
(1999)
J Biol Chem
, vol.274
, pp. 23948-23955
-
-
Weisenberger, D.J.1
Romano, L.J.2
-
121
-
-
0026321495
-
DNA deaminating ability and genotoxicity of nitric oxide and its progenitors
-
Wink DA, Kasprzak KS, Maragos CM, Elespuru RK, Misra M, Dunams TM, Cebula TA, Koch WH, Andrews AW, Allen JS, Keefe LK (1991) DNA deaminating ability and genotoxicity of nitric oxide and its progenitors. Science 254:1001-1003
-
(1991)
Science
, vol.254
, pp. 1001-1003
-
-
Wink, D.A.1
Kasprzak, K.S.2
Maragos, C.M.3
Elespuru, R.K.4
Misra, M.5
Dunams, T.M.6
Cebula, T.A.7
Koch, W.H.8
Andrews, A.W.9
Allen, J.S.10
Keefe, L.K.11
-
122
-
-
0037069366
-
Mbd4 inactivation increases C to T transition mutations and promotes gastrointestinal tumor formation
-
Wong E, Yang K, Kuraguchi M, Werling U, Avdievich E, Fan K, Fazzari M, Jin B, Brown AM, Lipkin M, Edelmann W (2002) Mbd4 inactivation increases C to T transition mutations and promotes gastrointestinal tumor formation. Proc Natl Acad Sci U S A 99:14937-14942
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14937-14942
-
-
Wong, E.1
Yang, K.2
Kuraguchi, M.3
Werling, U.4
Avdievich, E.5
Fan, K.6
Fazzari, M.7
Jin, B.8
Brown, A.M.9
Lipkin, M.10
Edelmann, W.11
-
123
-
-
0001129080
-
The bases of the nucleic acids of some bacterial and animal viruses: The occurrence of 5-hydroxymethylcytosine
-
Wyatt GR, Cohen SS (1953) The bases of the nucleic acids of some bacterial and animal viruses: the occurrence of 5-hydroxymethylcytosine. Biochem J 55:774-782
-
(1953)
Biochem J
, vol.55
, pp. 774-782
-
-
Wyatt, G.R.1
Cohen, S.S.2
-
124
-
-
0027977001
-
Cytosine deaminations catalyzed by DNA cytosine methyltransferases are unlikely to be the major cause of mutational hot spots at sites of cytosine methylation in Escherichia coli
-
Wyszynski M, Gabbara S, Bhagwat AS (1994) Cytosine deaminations catalyzed by DNA cytosine methyltransferases are unlikely to be the major cause of mutational hot spots at sites of cytosine methylation in Escherichia coli. Proc Natl Acad Sci USA 91:1574-1578
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 1574-1578
-
-
Wyszynski, M.1
Gabbara, S.2
Bhagwat, A.S.3
-
125
-
-
0029159759
-
Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals
-
Yamanaka S, Balestra ME, Ferrell LD, Fan J, Arnold KS, Taylor S, Taylor JM, Innerarity TL (1995) Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. Proc Natl Acad Sci U S A 92:8483-8487
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 8483-8487
-
-
Yamanaka, S.1
Balestra, M.E.2
Ferrell, L.D.3
Fan, J.4
Arnold, K.S.5
Taylor, S.6
Taylor, J.M.7
Innerarity, T.L.8
-
126
-
-
0029050606
-
HhaI and HpaII DNA methyltransferases bind DNA mismatches, methylate uracil and block DNA repair
-
Yang AS, Shen JC, Zingg JM, Mi S, Jones PA (1995) HhaI and HpaII DNA methyltransferases bind DNA mismatches, methylate uracil and block DNA repair. Nucleic Acids Res 23:1380-1387
-
(1995)
Nucleic Acids Res
, vol.23
, pp. 1380-1387
-
-
Yang, A.S.1
Shen, J.C.2
Zingg, J.M.3
Mi, S.4
Jones, P.A.5
-
127
-
-
0029927415
-
The rate of CpG mutation in Alu repetitive elements within the p53 tumor suppressor gene in the primate germline
-
Yang AS, Gonzalgo ML, Zingg JM, Millar RP, Buckley JD, Jones PA (1996b) The rate of CpG mutation in Alu repetitive elements within the p53 tumor suppressor gene in the primate germline. J Mol Biol 258:240-250
-
(1996)
J Mol Biol
, vol.258
, pp. 240-250
-
-
Yang, A.S.1
Gonzalgo, M.L.2
Zingg, J.M.3
Millar, R.P.4
Buckley, J.D.5
Jones, P.A.6
-
128
-
-
0028794055
-
A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine
-
Yebra MJ, Bhagwat AS (1995) A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine. Biochemistry 34:14752-14757
-
(1995)
Biochemistry
, vol.34
, pp. 14752-14757
-
-
Yebra, M.J.1
Bhagwat, A.S.2
-
129
-
-
0035477426
-
Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: Similarities with the p53 mutation spectrum in smoking-associated lung cancers
-
Yoon JH, Smith LE, Feng Z, Tang M, Lee CS, Pfeifer GP (2001) Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers. Cancer Res 61:7110-7117
-
(2001)
Cancer Res
, vol.61
, pp. 7110-7117
-
-
Yoon, J.H.1
Smith, L.E.2
Feng, Z.3
Tang, M.4
Lee, C.S.5
Pfeifer, G.P.6
-
130
-
-
0344875199
-
Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair
-
Yoon JH, Iwai S, O'Connor TR, Pfeifer GP (2003) Human thymine DNA glycosylase (TDG) and methyl-CpG-binding protein 4 (MBD4) excise thymine glycol (Tg) from a Tg:G mispair. Nucleic Acids Res 31:5399-5404
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 5399-5404
-
-
Yoon, J.H.1
Iwai, S.2
O'Connor, T.R.3
Pfeifer, G.P.4
-
131
-
-
0032732425
-
Involvement of 5-methylcytosine in sunlight-induced mutagenesis
-
You YH, Li C, Pfeifer GP (1999) Involvement of 5-methylcytosine in sunlight-induced mutagenesis. J Mol Biol 293:493-503
-
(1999)
J Mol Biol
, vol.293
, pp. 493-503
-
-
You, Y.H.1
Li, C.2
Pfeifer, G.P.3
-
132
-
-
0035977005
-
Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells
-
You YH, Lee DH, Yoon JH, Nakajima S, Yasui A, Pfeifer GP (2001) Cyclobutane pyrimidine dimers are responsible for the vast majority of mutations induced by UVB irradiation in mammalian cells. J Biol Chem 276:44688-44694
-
(2001)
J Biol Chem
, vol.276
, pp. 44688-44694
-
-
You, Y.H.1
Lee, D.H.2
Yoon, J.H.3
Nakajima, S.4
Yasui, A.5
Pfeifer, G.P.6
-
133
-
-
0142104232
-
Independent generation of 5-(2′-deoxycytidinyl)methyl radical and the formation of a novel cross-link lesion between 5-methylcytosine and guanine
-
Zhang Q, Wang Y (2003) Independent generation of 5-(2′- deoxycytidinyl)methyl radical and the formation of a novel cross-link lesion between 5-methylcytosine and guanine. J Am Chem Soc 125:12795-12802
-
(2003)
J Am Chem Soc
, vol.125
, pp. 12795-12802
-
-
Zhang, Q.1
Wang, Y.2
-
134
-
-
0031754914
-
P53 gene mutations in rectal cancer associated with schistosomiasis japonica in Chinese patients
-
Zhang R, Takahashi S, Orita S, Yoshida A, Maruyama H, Shirai T, Ohta N (1998) p53 gene mutations in rectal cancer associated with schistosomiasis japonica in Chinese patients. Cancer Lett 131:215-221
-
(1998)
Cancer Lett
, vol.131
, pp. 215-221
-
-
Zhang, R.1
Takahashi, S.2
Orita, S.3
Yoshida, A.4
Maruyama, H.5
Shirai, T.6
Ohta, N.7
-
135
-
-
0347724022
-
Endogenous 5-methylcytosine protects neighboring guanines from N7 and O6-methylation and O6-pyridyloxobutylation by the tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
-
Ziegel R, Shallop A, Upadhyaya P, Jones R, Tretyakova N (2004) Endogenous 5-methylcytosine protects neighboring guanines from N7 and O6-methylation and O6-pyridyloxobutylation by the tobacco carcinogen 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanone. Biochemistry 43:540-549
-
(2004)
Biochemistry
, vol.43
, pp. 540-549
-
-
Ziegel, R.1
Shallop, A.2
Upadhyaya, P.3
Jones, R.4
Tretyakova, N.5
-
136
-
-
0027166864
-
Mutation hot spots due to sunlight in the p53 gene of nonmelanoma skin cancers
-
Ziegler A, Leffell DJ, Kunala S, Sharma HW, Gailani M, Simon JA, Halperin AJ, Baden HP, Shapiro PE, Bale AE, Brash DE (1993) Mutation hot spots due to sunlight in the p53 gene of nonmelanoma skin cancers. Proc Natl Acad Sci USA 90:4216-4220
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 4216-4220
-
-
Ziegler, A.1
Leffell, D.J.2
Kunala, S.3
Sharma, H.W.4
Gailani, M.5
Simon, J.A.6
Halperin, A.J.7
Baden, H.P.8
Shapiro, P.E.9
Bale, A.E.10
Brash, D.E.11
-
137
-
-
0028596185
-
Sunburn and p53 in the onset of skin cancer
-
Ziegler A, Jonason AS, Leffell DJ, Simon JA, Sharma HW, Kimmelman J, Remington L, Jacks T, Brash DE (1994) Sunburn and p53 in the onset of skin cancer. Nature 372:773-776
-
(1994)
Nature
, vol.372
, pp. 773-776
-
-
Ziegler, A.1
Jonason, A.S.2
Leffell, D.J.3
Simon, J.A.4
Sharma, H.W.5
Kimmelman, J.6
Remington, L.7
Jacks, T.8
Brash, D.E.9
|