Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: Similarities with the p53 mutation spectrum in smoking-associated lung cancers

Cancer Research

Volumn 61, Issue 19, 2001, Pages 7110-7117

  Yoon, Jung Hoon ^a,b   Smith, Leslie E ^a   Pfeifer, Gerd P ^a   Lee, Chong Soon ^b   Feng, Zaohui ^c   Tang, Moon Shong ^c  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b Yeungnam University   (South Korea)

^c NEW YORK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7,8,9,10 TETRAHYDRO 7BETA,8ALPHA DIHYDROXYBENZO[A]PYRENE 9ALPHA,10ALPHA OXIDE; DIHYDROXYBENZO[A]PYRENE OXIDE; DINUCLEOTIDE; DNA; GUANINE; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN P53; PYRENE DERIVATIVE; THYMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CIGARETTE SMOKING; CONTROLLED STUDY; DNA ADDUCT; EMBRYO; FIBROBLAST; GENE MUTATION; GENE SEQUENCE; LUNG CANCER; MAMMAL CELL; METHYLATION; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; TRANSGENE;

7,8-DIHYDRO-7,8-DIHYDROXYBENZO(A)PYRENE 9,10-OXIDE; ANIMALS; BACTERIAL PROTEINS; BASE SEQUENCE; CARCINOGENS; CPG ISLANDS; DNA ADDUCTS; DNA METHYLATION; ESCHERICHIA COLI PROTEINS; FIBROBLASTS; GENES, P53; GENES, SUPPRESSOR; GENETIC VECTORS; HUMANS; LUNG NEOPLASMS; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTAGENS; REPRESSOR PROTEINS; RNA, TRANSFER; SMOKING; SUBSTRATE SPECIFICITY; TRANSCRIPTION FACTORS; TRANSGENES; VIRAL PROTEINS;

EID: 0035477426     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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