Effect of diet on cancer development: Is oxidative DNA damage a biomarker?

Free Radical Biology and Medicine

Volumn 32, Issue 10, 2002, Pages 968-974

  Halliwell, Barry ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

8 Hydroxy 2 deoxyguanosine; Cancer; Diabetes; Free radical; Mass spectrometry; Oxidative DNA damage

Indexed keywords

5 HYDROXYMETHYLURACIL; 8 HYDROXYGUANINE; ALPHA TOCOPHEROL; ASBESTOS; ASCORBIC ACID; BENZO[A]PYRENE; BETA CAROTENE; BIOLOGICAL MARKER; CARCINOGEN; CIGARETTE SMOKE; CLOFIBRATE; DEOXYGUANOSINE DERIVATIVE; DEOXYGUANOSINE DIPHOSPHATE; DEOXYGUANOSINE TRIPHOSPHATE; DIMETHYLBENZ[A]ANTHRACENE; FLAVONOID; NICKEL; UBIDECARENONE; UNCLASSIFIED DRUG;

CANCER INCIDENCE; CANCER RISK; CARCINOGENESIS; CHRONIC INFLAMMATION; DIABETES MELLITUS; DIETARY INTAKE; DNA DAMAGE; DRUG EFFECT; FRUIT; HUMAN; IN VIVO STUDY; MUTAGENICITY; MUTATION RATE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; REVIEW; RHEUMATOID ARTHRITIS; STEADY STATE; URINARY EXCRETION; VEGETABLE;

EID: 0037093739     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(02)00808-0     Document Type: Article

References (101)

1. Validation of markers for their relevance to health and disease
2. Markers of oxidative damage and antioxidant protection: Current status and relevance to disease
3. Analysis of a form of oxidative DNA damage, 8-hydroxy-2′-deoxyguanosine, as a marker of cellular oxidative stress during carcinogenesis
4. The effects of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry
5. Why and how should we measure oxidative DNA damage in nutritional studies? How far have we come?
6. ESCODD: European Standards Committee on Oxidative DNA Damage
7. Development of a quality control material for the measurement of 8-oxo-7,8-dihydro-2′-deoxyguanosine, an in vivo marker of oxidative stress, and a comparison of results from different laboratories
8. Comparison of results from different laboratories in measuring 8-oxo-2′-deoxyguanosine in synthetic oligonucleotides
9. Inter-laboratory validation of procedures for measuring 8-oxo-7,8-Dihydroguanine/8-oxo-7,8-dihydro-2′-deoxyguanosine in DNA
10. Damage to DNA by reactive oxygen and nitrogen species: A role in inflammatory disease and progression to cancer
11. Gas chromatography-mass spectrometry analysis of DNA: Optimisation of protocols for isolation and analysis of DNA from human blood
12. Measurement of oxidative DNA damage by gas chromatography-mass spectrometry: Ethanethiol prevents artifactual generation of oxidised DNA bases
13. Spontaneous cancer and its possible relationship to oxygen metabolism
14. Oxidants, antioxidants and the degenerative disease of aging
15. The role of 8-hydroxyguanine in carcinogenesis
16. Establishing the significance and optimal intake of dietary antioxidants: The biomarker concept
17. Experimental study of oxidative DNA damage
18. Urinary 8-oxo-2′-deoxyguanosine - Source, significance and supplements
19. Markers of oxidative damage to DNA: Antioxidants and molecular damage
20. DNA oxidation matters: The HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine
21. 8-Hydroxydeoxyguanosine and 8- hydroxyguanine as biomarkers of oxidative DNA damage
22. Measurement of 8-oxo-2′-deoxyguanosine and 8-oxo-2′-deoxyadenosine in DNA and human urine by high performance liquid chromatography-electrospray tanden mass spectrometry
23. Urinary 8OHdG in infants and children
24. A carbon column-based liquid chromatography electrochemical approach to routine 8OHdG measurements in urine and other biological matrices: A one year evaluation of methods
25. Fast quantification of the urinary marker of oxidative stress 8OHdG using solid-phase extraction and HPLC with triple-stage quadrupole mass detection
26. 8-Oxo-7,8-dihydroguanine and 8-oxo-7,8-dihydro-2′-deoxyguanosine levels in human urine do not depend on diet
27. Hydrolytic elimination of a mutagenic nucleotide, 8-oxodGTP, by human 18-kiloDalton protein: Sanitization of nucleotide pool
28. Urine 8-oxo-7,8dihydro-2′-deoxyguanosine versus 5-(hydroxymethyl)uracil as DNA oxidation marker in adriamycin-treated patients
29. Analysis of methylated and oxidised purines in urine by capillary gas chromatography-mass spectrometry
30. Simultaneous determination of five oxidative DNA lesions in human urine
31. Mutagenicity and repair of oxidative DNA damage: Insights from studies using defined lesions
32. Genotoxicity of ribo- and deoxyribonucleosides of 8-hydroxyguanine, 5-hydroxycytosine, and 2-hydroxyadenine: Induction of SCE in human lymphocytes and mutagenicity in Salmonella typimurium TA 100
33. The mutations induced by oxidatively damaged nucleotides, 5-formyl-dUTP and 5-hydroxy-dCTP, in Escherichia coli
34. DNA adducts in human carcinogenesis: Etiological relevance and structure-activity relationship
35. Human DNA adduct measurements: State of the art
36. Correlation of DNA adduct levels with tumor incidence: Carcinogenic potency of DNA adducts
37. Tomato consumption modulates oxidative DNA damage in humans
38. Consumption of vegetables reduces genetic damage in humans: First results of a human intervention trial with carotenoid-rich foods
39. Reduction of oxidative damage in humans by Brussels sprouts
40. Supplementation with fruit and vegetable extracts may decrease DNA damage in the peripheral lymphocytes of an elderly population
41. Effect of increased vegetable and fruit consumption on markers of oxidative cellular damage
42. No influence of beta carotene on oxidative DNA damage in male smokers
43. Effect of antioxidant vitamin supplementation on markers of DNA damage and plasma antioxidants
44. No effect of supplementation with vitamin E, ascorbic acid, or coenzyme Q10 on oxidative DNA damage estimated by 8-oxo-7, 8-dihydro-2′-deoxyguanosine excretion in smokers
45. 2-isoprostanes) are not correlated in healthy human subjects
46. Vitamin C exhibits prooxidant properties
47. Can antioxidant vitamins materially reduce oxidative damage in humans?
48. The effects of vitamin C and vitamin E on oxidative DNA damage: Results from a randomised controlled trial
49. Long-term effects of vitamin E, vitamin C, and combined supplementation on urinary 7-Hydro-8-oxo-2′-deoxyguanosine, serum cholesterol oxidation products, and oxidation resistance of lipids in nondepleted men
50. Oxidative DNA damage measured in human lymphocytes: Large differences between sexes and between countries, and correlations with heart disease mortality rates
51. Beta-carotene takes a collective beating
52. 8-Hydroxydeoxyguanosine in DNA from leukocytes of healthy adults: Relationship with cigarette smoking, environmental tobacco smoke, alcohol and coffee consumption
53. Cigarette smoking induces formation of 8-hydroxydeoxyguanosine, one of the oxidative DNA damages, in human peripheral leukocytes
54. Cigarette smoking induces an increase in oxidative DNA damage, 8-hydroxydeoxyguanosine, in a central site of the human lung
55. A multi-biomarker approach to study the effects of smoking on oxidative DNA damage and repair and antioxidative defense mechanisms
56. Formation of 8-hydroxydeoxyguanosine in liver DNA of rats following long-term exposure to a peroxisome proliferator
57. Mitochondrial damage by the "pro-oxidant" peroxisome proliferator clofibrate
58. Correlation of individual papilloma latency time with DNA adducts, 8-hydroxy-2′-deoxyguanosine, and the rate of DNA synthesis in the epidermis of mice treated with 7,12-dimethylbenz[a]anthracene
59. Nickel(II)-mediated oxidative DNA base damage in renal and hepatic chromatin of pregnant rats and their fetuses. Possible relevance to carcinogenesis
60. Benzo[a]pyrene diol-epoxide-I-DNA and oxidative DNA adducts associated with gastric adenocarcinoma
61. Association between 8-hydroxy-2′-deoxyguanosine levels in DNA of workers highly exposed to asbestos and their clinical data, occupational and non-occupational confounding factors, and cancer
62. Effect of varying dietary fat levels on rat growth and oxidative DNA damage
63. Plasma polyphenols and antioxidants, oxidative DNA damage and endothelial function in a diet and wine intervention study in humans
64. Lung carcinogenesis and formation of 8- hydroxy-deoxyguanosine in mice by diesel exhaust particles
65. High-fat-diet-induced oxidative DNA damage estimated by 8-oxo-7,8-dihydro-2′-deoxyguanosine excretion in rats
66. Chronic infections and inflammatory processes as cancer risk factors: Possible role of nitric oxide in carcinogenesis
67. Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis
68. The COX-2 inhibitor nimesulide suppresses superoxide and 8-hydroxy-deoxyguanosine formation, and stimulates apoptosis in mucosa during early colonic inflammation in rats
69. Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma
70. Vitamin E reduces chromosomal damage and inhibits hepatic tumour formation in a transgenic mouse model
71. Early oxidative DNA damages and late development of lung cancer in diesel exhaust-exposed rats
72. Spontaneous tumorigenesis in mice defective in the in MTH1 gene encoding 8-oxo-dGTPase
73. DNA base modifications and antioxidant enzyme activities in human benign prostatic hyperplasia
74. Oxidative DNA damage and cellular sensitivity to oxidative stress in human autoimmune diseases
75. Oxygen radicals, nitric oxide and human inflammatory joint disease
76. Risk of malignancy among patients with rheumatic conditions
77. Oxidative damage to DNA in diabetes mellitus
78. Increased oxidative damage to all DNA bases in patients with type II diabetes mellitus
79. New biomarker evidence of oxidative DNA damage in patients with non-insulin-dependent diabetes mellitus
80. Pancreatic cancer and sugar diabetes
81. Diabetes, body size, and risk of endometrial cancer
82. Colorectal cancer: Another complication of diabetes mellitus?
83. Anthropometric and other risk factors for ovarian cancer in a case-control study
84. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation
85. DNA oxidative damage in leukocytes correlates with the severity of HCV-related liver disease: Validation in an open population study
86. Effect of endurance exercise on the tissue 8-hydroxy-deoxyguanosine content in dogs
87. Age and organ dependent spontaneous generation of nuclear 8-hydroxydeoxyguanosine in male Fischer 344 rats
88. Sensitive detection of 8-hydroxy-2′-deoxyguanosine in DNA by 32P-postlabeling assay and the basal levels in rat tissues
89. Detection of endogenous malondialdehyde-deoxyguanosine adducts in human liver
90. Etheno-adduct-forming chemicals: From mutagenicity testing to tumor mutation spectra
91. Lipid peroxidation-induced etheno-DNA adducts in the liver of patients with the genetic metal storage disorders Wilson's disease and primary hemochromatosis
92. Genotoxic lipid peroxidation products: Their DNA damaging properties and role in formation of endogenous DNA adducts
93. Novel repair action of vitamin C upon in vivo oxidative DNA damage
94. Mutagenesis by 8-oxoguanine: An enemy within
95. Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening
96. Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology
97. Antioxidant defence mechanisms; From the beginning to the end (of the beginning)
98. Oxidative stress, human genetic variation and disease
99. Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk