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Volumn 359, Issue 1446, 2004, Pages 943-964

The N-methyl D-aspartate receptor glycine site and D-serine metabolism: An evolutionary perspective

Author keywords

D amino acid; D serine; Glutamate; Glycine; Racemase; Schizophrenia

Indexed keywords

BRAIN; EVOLUTION;

EID: 2942718893     PISSN: 09628436     EISSN: None     Source Type: Journal    
DOI: 10.1098/rstb.2003.1399     Document Type: Review
Times cited : (95)

References (270)
  • 1
    • 0028849716 scopus 로고
    • Intercellular communication in the brain: Wiring versus volume transmission
    • Agnati, L. F., Zoli, M., Stromberg, I. & Fuxe, K. 1995 Intercellular communication in the brain: wiring versus volume transmission. Neuroscience 69, 711-726.
    • (1995) Neuroscience , vol.69 , pp. 711-726
    • Agnati, L.F.1    Zoli, M.2    Stromberg, I.3    Fuxe, K.4
  • 2
    • 0037595545 scopus 로고    scopus 로고
    • Facilitation of spinal NMDA receptor currents by spillover of synaptically released glycine
    • Ahmadi, S., Muth-Selbach, U., Lauterbach, A., Lipfert, P., Neuhuber, W. L. & Zeilhofer, H. U. 2003 Facilitation of spinal NMDA receptor currents by spillover of synaptically released glycine. Science 300, 2094-2097.
    • (2003) Science , vol.300 , pp. 2094-2097
    • Ahmadi, S.1    Muth-Selbach, U.2    Lauterbach, A.3    Lipfert, P.4    Neuhuber, W.L.5    Zeilhofer, H.U.6
  • 3
    • 0028048223 scopus 로고
    • Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats
    • Akazawa, C., Shigemoto, R., Bessho, Y., Nakanishi, S. & Mizuno, N. 1994 Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats. J. Comp. Neurol. 347, 150-160.
    • (1994) J. Comp. Neurol. , vol.347 , pp. 150-160
    • Akazawa, C.1    Shigemoto, R.2    Bessho, Y.3    Nakanishi, S.4    Mizuno, N.5
  • 4
    • 0028044574 scopus 로고
    • Evolutionary relationships among pyridoxal-5′-phosphate-dependent enzymes. Regio-specific alpha, beta and gamma families
    • Alexander, F. W., Sandmeier, E., Mehta, P. K. & Christen, P. 1994 Evolutionary relationships among pyridoxal-5′-phosphate-dependent enzymes. Regio-specific alpha, beta and gamma families. Eur. J. Biochem. 219, 953-960.
    • (1994) Eur. J. Biochem. , vol.219 , pp. 953-960
    • Alexander, F.W.1    Sandmeier, E.2    Mehta, P.K.3    Christen, P.4
  • 5
    • 0014408213 scopus 로고
    • The biosynthesis of D-serine ethanolamine phosphate in the earthworm Megascolides cameroni
    • Allen, A. K. & Rosenberg, H. 1968 The biosynthesis of D-serine ethanolamine phosphate in the earthworm Megascolides cameroni. Biochim. Biophys. Acta 152, 208-210.
    • (1968) Biochim. Biophys. Acta , vol.152 , pp. 208-210
    • Allen, A.K.1    Rosenberg, H.2
  • 6
    • 0014489603 scopus 로고
    • A comparison of the concentration of glycine, a transmitter suspect, in different areas of the brain and spinal cord in seven different vertebrates
    • Aprison, M. H., Shank, R. P. & Davidoff, R. A. 1969 A comparison of the concentration of glycine, a transmitter suspect, in different areas of the brain and spinal cord in seven different vertebrates. Comp. Biochem. Physiol. 28, 1345-1355.
    • (1969) Comp. Biochem. Physiol. , vol.28 , pp. 1345-1355
    • Aprison, M.H.1    Shank, R.P.2    Davidoff, R.A.3
  • 8
    • 0033636314 scopus 로고    scopus 로고
    • Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: Crystal structures of the GluR2 ligand binding core
    • Armstrong, N. & Gouaux, E. 2000 Mechanisms for activation and antagonism of an AMPA-sensitive glutamate receptor: crystal structures of the GluR2 ligand binding core. Neuron 28, 165-181.
    • (2000) Neuron , vol.28 , pp. 165-181
    • Armstrong, N.1    Gouaux, E.2
  • 9
    • 0032578635 scopus 로고    scopus 로고
    • Structure of a glutamate-receptor ligand-binding core in complex with kainate
    • Armstrong, N., Sun, Y., Chen, G. Q. & Gouaux, E. 1998 Structure of a glutamate-receptor ligand-binding core in complex with kainate. Nature 395, 913-917.
    • (1998) Nature , vol.395 , pp. 913-917
    • Armstrong, N.1    Sun, Y.2    Chen, G.Q.3    Gouaux, E.4
  • 10
    • 2942755079 scopus 로고
    • Amino acid oxidase activity in the fat body and malpighian tubes of some insects
    • Auclair, J. L. 1959 Amino acid oxidase activity in the fat body and malpighian tubes of some insects. J. Insect Physiol. 3, 57-62.
    • (1959) J. Insect Physiol. , vol.3 , pp. 57-62
    • Auclair, J.L.1
  • 11
    • 0027235855 scopus 로고
    • Nonsynaptic diffusion neurotransmission (NDN) in the brain
    • Bach-y-Rita, P. 1993 Nonsynaptic diffusion neurotransmission (NDN) in the brain. Neurochem. Int. 23, 297-318.
    • (1993) Neurochem. Int. , vol.23 , pp. 297-318
    • Bach-y-Rita, P.1
  • 12
    • 0036703884 scopus 로고    scopus 로고
    • Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant non-habituating hyperactivity
    • Ballard, T. M., Pauly-Evers, M., Higgins, G. A., Ouagazzal, A. M., Mutel, V., Borroni, E., Kemp, J. A., Bluethmann, H. & Kew, J. N. 2002 Severe impairment of NMDA receptor function in mice carrying targeted point mutations in the glycine binding site results in drug-resistant non-habituating hyperactivity. J. Neurosci. 22, 6713-6723.
    • (2002) J. Neurosci. , vol.22 , pp. 6713-6723
    • Ballard, T.M.1    Pauly-Evers, M.2    Higgins, G.A.3    Ouagazzal, A.M.4    Mutel, V.5    Borroni, E.6    Kemp, J.A.7    Bluethmann, H.8    Kew, J.N.9
  • 13
    • 0037312558 scopus 로고    scopus 로고
    • Activation of NR1/NR2B NMDA receptors
    • Banke, T. G. & Traynelis, S. F. 2003 Activation of NR1/NR2B NMDA receptors. Nature Neurosci. 6, 144-152.
    • (2003) Nature Neurosci. , vol.6 , pp. 144-152
    • Banke, T.G.1    Traynelis, S.F.2
  • 15
    • 0343376117 scopus 로고    scopus 로고
    • Intersynaptic diffusion of neurotransmitter
    • Barbour, B. & Hausser, M. 1997 Intersynaptic diffusion of neurotransmitter. Trends Neurosci. 20, 377-384.
    • (1997) Trends Neurosci. , vol.20 , pp. 377-384
    • Barbour, B.1    Hausser, M.2
  • 16
    • 0018069078 scopus 로고
    • The monoamine innervation of rat cerebral cortex: Synaptic and non-synaptic axon terminals
    • Beaudet, A. & Descarries, L. 1978 The monoamine innervation of rat cerebral cortex: synaptic and non-synaptic axon terminals. Neuroscience 3, 851-860.
    • (1978) Neuroscience , vol.3 , pp. 851-860
    • Beaudet, A.1    Descarries, L.2
  • 17
    • 0038518200 scopus 로고    scopus 로고
    • Dating the tree of life
    • Benton, M. J. & Ayala, F. J. 2003 Dating the tree of life. Science 300, 1698-1700.
    • (2003) Science , vol.300 , pp. 1698-1700
    • Benton, M.J.1    Ayala, F.J.2
  • 18
    • 0032415129 scopus 로고    scopus 로고
    • Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses
    • Berger, A. J., Dieudonne, S. & Ascher, P. 1998 Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses. J. Neurophysiol. 80, 3336-3340.
    • (1998) J. Neurophysiol. , vol.80 , pp. 3336-3340
    • Berger, A.J.1    Dieudonne, S.2    Ascher, P.3
  • 19
    • 0032441894 scopus 로고    scopus 로고
    • Modulation of N-methyl-D-aspartate receptor function by glycine transport
    • Bergeron, R., Meyer, T. M., Coyle, J. T. & Greene, R. W. 1998 Modulation of N-methyl-D-aspartate receptor function by glycine transport. Proc. Natl Acad. Sci. USA 95, 15 730-15 734.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 15730-15734
    • Bergeron, R.1    Meyer, T.M.2    Coyle, J.T.3    Greene, R.W.4
  • 20
    • 0025014005 scopus 로고
    • Endogenous neurotransmitter activates N-methyl-D-aspartate receptors on differentiating neurons in embryonic cortex
    • Blanton, M. G., Lo Turco, J. J. & Kriegstein, A. R. 1990 Endogenous neurotransmitter activates N-methyl-D-aspartate receptors on differentiating neurons in embryonic cortex. Proc. Natl Acad. Sci. USA 87, 8027-8030.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 8027-8030
    • Blanton, M.G.1    Lo Turco, J.J.2    Kriegstein, A.R.3
  • 21
    • 17344364477 scopus 로고    scopus 로고
    • Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21
    • Blouin, J. L. (and 27 others) 1998 Schizophrenia susceptibility loci on chromosomes 13q32 and 8p21. Nature Genet. 20, 70-73.
    • (1998) Nature Genet. , vol.20 , pp. 70-73
    • Blouin, J.L.1
  • 23
    • 0035974849 scopus 로고    scopus 로고
    • The C. elegans glutamate receptor subunit NMR-1 is required for slow NMDA-activated currents that regulate reversal frequency during locomotion
    • Brockie, P. J., Mellem, J. E., Hills, T., Madsen, D. M. & Maricq, A. V. 2001 The C. elegans glutamate receptor subunit NMR-1 is required for slow NMDA-activated currents that regulate reversal frequency during locomotion. Neuron 31, 617-630.
    • (2001) Neuron , vol.31 , pp. 617-630
    • Brockie, P.J.1    Mellem, J.E.2    Hills, T.3    Madsen, D.M.4    Maricq, A.V.5
  • 24
    • 0037354447 scopus 로고    scopus 로고
    • Chromatographic determination of L- and D-amino acids in plants
    • Bruckner, H. & Westhauser, T. 2003 Chromatographic determination of L- and D-amino acids in plants. Amino Acids 24, 43-55.
    • (2003) Amino Acids , vol.24 , pp. 43-55
    • Bruckner, H.1    Westhauser, T.2
  • 25
    • 0027179435 scopus 로고
    • Chirality of amino acids of microorganisms used in food biotechnology
    • Bruckner, H., Becker, D. & Lupke, M. 1993 Chirality of amino acids of microorganisms used in food biotechnology. Chirality 5, 385-392.
    • (1993) Chirality , vol.5 , pp. 385-392
    • Bruckner, H.1    Becker, D.2    Lupke, M.3
  • 26
    • 0028216126 scopus 로고
    • Quantification of D-amino acids in human urine using GC-MS and HPLC
    • Bruckner, H., Haasmann, S. & Friedrich, A. 1994 Quantification of D-amino acids in human urine using GC-MS and HPLC. Amino Acids 6, 205-211.
    • (1994) Amino Acids , vol.6 , pp. 205-211
    • Bruckner, H.1    Haasmann, S.2    Friedrich, A.3
  • 28
    • 0033198725 scopus 로고    scopus 로고
    • Paracrine neurotransmission in the CNS: Involvement of 5-HT
    • Bunin, M. A. & Wightman, R. M. 1999 Paracrine neurotransmission in the CNS: involvement of 5-HT. Trends Neurosci. 22, 377-382.
    • (1999) Trends Neurosci. , vol.22 , pp. 377-382
    • Bunin, M.A.1    Wightman, R.M.2
  • 29
    • 0030830809 scopus 로고    scopus 로고
    • Two novel types of L-glutamate receptors with affinities for NMDA and L-cysteine in the olfactory organ of the Caribbean spiny lobster Panulirus argus
    • Burgess, M. F. & Derby, C. D. 1997 Two novel types of L-glutamate receptors with affinities for NMDA and L-cysteine in the olfactory organ of the Caribbean spiny lobster Panulirus argus. Brain Res. 771, 292-304.
    • (1997) Brain Res. , vol.771 , pp. 292-304
    • Burgess, M.F.1    Derby, C.D.2
  • 30
    • 0022510955 scopus 로고
    • Glycine neurons in the brain and spinal cord. Antibody production and immunocytochemical localization
    • Campistron, G., Buijs, R. M. & Geffard, M. 1986 Glycine neurons in the brain and spinal cord. Antibody production and immunocytochemical localization. Brain Res. 376, 400-405.
    • (1986) Brain Res. , vol.376 , pp. 400-405
    • Campistron, G.1    Buijs, R.M.2    Geffard, M.3
  • 31
    • 0016682243 scopus 로고
    • D-Serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis
    • Carone, F. A. & Ganote, C. E. 1975 D-Serine nephrotoxicity. The nature of proteinuria, glucosuria, and aminoaciduria in acute tubular necrosis. Arch. Pathol. 99, 658-662.
    • (1975) Arch. Pathol. , vol.99 , pp. 658-662
    • Carone, F.A.1    Ganote, C.E.2
  • 32
    • 0034633668 scopus 로고    scopus 로고
    • Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse
    • Casado, M., Dieudonne, S. & Ascher, P. 2000 Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse. Proc. Natl Acad. Sci. USA 97, 11 593-11 597.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 11593-11597
    • Casado, M.1    Dieudonne, S.2    Ascher, P.3
  • 33
    • 0028174008 scopus 로고
    • D-Cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: An open-label study
    • Cascella, N. G., Macciardi, F., Cavallini, C. & Smeraldi, E. 1994 D-Cycloserine adjuvant therapy to conventional neuroleptic treatment in schizophrenia: an open-label study. J. Neural Transm. Gen. Sect. 95, 105-111.
    • (1994) J. Neural Transm. Gen. Sect. , vol.95 , pp. 105-111
    • Cascella, N.G.1    Macciardi, F.2    Cavallini, C.3    Smeraldi, E.4
  • 34
    • 0034663159 scopus 로고    scopus 로고
    • Developmental profile of the changing properties of NMDA receptors at cerebellar mossy fiber-granule cell synapses
    • Cathala, L., Misra, C. & Cull-Candy, S. 2000 Developmental profile of the changing properties of NMDA receptors at cerebellar mossy fiber-granule cell synapses. J. Neurosci. 20, 5899-5905.
    • (2000) J. Neurosci. , vol.20 , pp. 5899-5905
    • Cathala, L.1    Misra, C.2    Cull-Candy, S.3
  • 35
    • 0034970918 scopus 로고    scopus 로고
    • Blockade of the central generator of locomotor rhythm by non-competitive NMDA receptor antagonists in Drosophila larvae
    • Cattaert, D. & Birman, S. 2001 Blockade of the central generator of locomotor rhythm by non-competitive NMDA receptor antagonists in Drosophila larvae. J. Neurobiol. 48, 58-73.
    • (2001) J. Neurobiol. , vol.48 , pp. 58-73
    • Cattaert, D.1    Birman, S.2
  • 36
    • 0037074985 scopus 로고    scopus 로고
    • Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits
    • Chatterton J. E. (and 12 others) 2002 Excitatory glycine receptors containing the NR3 family of NMDA receptor subunits. Nature 415, 793-798.
    • (2002) Nature , vol.415 , pp. 793-798
    • Chatterton, J.E.1
  • 37
    • 0031471216 scopus 로고    scopus 로고
    • Overexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli: Application of a novel protein folding screen
    • Chen, G. Q. & Gouaux, E. 1997 Overexpression of a glutamate receptor (GluR2) ligand binding domain in Escherichia coli: application of a novel protein folding screen. Proc. Natl Acad. Sci. USA 94, 13 431-13 436.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 13431-13436
    • Chen, G.Q.1    Gouaux, E.2
  • 38
    • 0033576612 scopus 로고    scopus 로고
    • Functional characterization of a potassium-selective prokaryotic glutamate receptor
    • Chen, G. Q., Cui, C., Mayer, M. L. & Gouaux, E. 1999 Functional characterization of a potassium-selective prokaryotic glutamate receptor. Nature 402, 817-821.
    • (1999) Nature , vol.402 , pp. 817-821
    • Chen, G.Q.1    Cui, C.2    Mayer, M.L.3    Gouaux, E.4
  • 39
    • 0037320805 scopus 로고    scopus 로고
    • Glycine transporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo
    • Chen, L., Muhlhauser, M. & Yang, C. R. 2003 Glycine transporter-1 blockade potentiates NMDA-mediated responses in rat prefrontal cortical neurons in vitro and in vivo. J. Neurophysiol. 89, 691-703.
    • (2003) J. Neurophysiol. , vol.89 , pp. 691-703
    • Chen, L.1    Muhlhauser, M.2    Yang, C.R.3
  • 41
    • 0033015733 scopus 로고    scopus 로고
    • Molecular evolution of glutamate receptors: A primitive signaling mechanism that existed before plants and animals diverged
    • Chiu, J. C., DeSalle, R., Lam, H. M., Meisel, L. & Coruzzi, G. 1999 Molecular evolution of glutamate receptors: a primitive signaling mechanism that existed before plants and animals diverged. Mol. Biol. Evol. 16, 826-838.
    • (1999) Mol. Biol. Evol. , vol.16 , pp. 826-838
    • Chiu, J.C.1    Desalle, R.2    Lam, H.M.3    Meisel, L.4    Coruzzi, G.5
  • 42
    • 0035986865 scopus 로고    scopus 로고
    • Phylogenetic and expression analysis of the glutamate-receptor-like gene family in Arabidopsis thaliana
    • Chiu, J. C., Brenner, E. D., DeSalle, R., Nitabach, M. N., Holmes, T. C. & Coruzzi, G. M. 2002 Phylogenetic and expression analysis of the glutamate-receptor-like gene family in Arabidopsis thaliana. Mol. Biol. Evol. 19, 1066-1082.
    • (2002) Mol. Biol. Evol. , vol.19 , pp. 1066-1082
    • Chiu, J.C.1    Brenner, E.D.2    DeSalle, R.3    Nitabach, M.N.4    Holmes, T.C.5    Coruzzi, G.M.6
  • 43
    • 0027484142 scopus 로고
    • Presence of the N-methyl-D-aspartate-associated glycine receptor agonist, D-serine, in human temporal cortex: Comparison of normal, Parkinson and Alzheimer tissues
    • Chouinard, M. L., Gaitan, D. & Wood, P. L. 1993 Presence of the N-methyl-D-aspartate-associated glycine receptor agonist, D-serine, in human temporal cortex: comparison of normal, Parkinson and Alzheimer tissues. J. Neurochem. 61, 1561-1564.
    • (1993) J. Neurochem. , vol.61 , pp. 1561-1564
    • Chouinard, M.L.1    Gaitan, D.2    Wood, P.L.3
  • 44
    • 0025095302 scopus 로고
    • Role of amino acid transport and countertransport in nutrition and metabolism
    • Christensen, H. N. 1990 Role of amino acid transport and countertransport in nutrition and metabolism. Physiol. Rev. 70, 43-77.
    • (1990) Physiol. Rev. , vol.70 , pp. 43-77
    • Christensen, H.N.1
  • 45
    • 0037108758 scopus 로고    scopus 로고
    • Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia
    • Chumakov, I. (and 64 others) 2002 Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia. Proc. Natl Acad. Sci. USA 99, 13 675-13 680.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13675-13680
    • Chumakov, I.1
  • 46
    • 0026028076 scopus 로고
    • 2+ in cultured frog tectal cells mediated by direct activation of NMDA receptor channels
    • 2+ in cultured frog tectal cells mediated by direct activation of NMDA receptor channels. Neuron 6, 259-267.
    • (1991) Neuron , vol.6 , pp. 259-267
    • Cline, H.T.1    Tsien, R.W.2
  • 47
    • 0037109055 scopus 로고    scopus 로고
    • The discovery of susceptibility genes for mental disorders
    • Cloninger, C. R. 2002 The discovery of susceptibility genes for mental disorders. Proc. Natl Acad. Sci. USA 99, 13 365-13 367.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13365-13367
    • Cloninger, C.R.1
  • 49
    • 0014671457 scopus 로고
    • D-Amino acids in animals
    • Corrigan, J. J. 1969 D-Amino acids in animals. Science 164, 142-149.
    • (1969) Science , vol.164 , pp. 142-149
    • Corrigan, J.J.1
  • 50
    • 0013893865 scopus 로고
    • The occurrence of certain D-amino acids in insects
    • Corrigan, J. J. & Srinivasan, N. G. 1966 The occurrence of certain D-amino acids in insects. Biochemistry 5, 1185-1190.
    • (1966) Biochemistry , vol.5 , pp. 1185-1190
    • Corrigan, J.J.1    Srinivasan, N.G.2
  • 51
    • 50549191186 scopus 로고
    • Determination of D-amino acid oxidase activity in insect tissues using D-allohydroxyproline as substrate
    • Corrigan, J. J., Wellner, D. & Meister, A. 1963 Determination of D-amino acid oxidase activity in insect tissues using D-allohydroxyproline as substrate. Biochim. Biophys. Acta 73, 50-56.
    • (1963) Biochim. Biophys. Acta , vol.73 , pp. 50-56
    • Corrigan, J.J.1    Wellner, D.2    Meister, A.3
  • 52
    • 0037942706 scopus 로고    scopus 로고
    • Ionotropic glutamate receptors as therapeutic targets in schizophrenia
    • Coyle, J. T., Tsai, G. & Goff, D. C. 2002 Ionotropic glutamate receptors as therapeutic targets in schizophrenia. Curr. Drug Target CNS Neurol. Disord. 1, 183-189.
    • (2002) Curr. Drug Target CNS Neurol. Disord. , vol.1 , pp. 183-189
    • Coyle, J.T.1    Tsai, G.2    Goff, D.C.3
  • 53
    • 0032192552 scopus 로고    scopus 로고
    • NMDA receptor diversity in the cerebellum: Identification of subunits contributing to functional receptors
    • Cull-Candy, S. G., Brickley, S. G., Misra, C., Feldmeyer, D., Momiyama, A. & Farrant, M. 1998 NMDA receptor diversity in the cerebellum: identification of subunits contributing to functional receptors. Neuropharmacology 37, 1369-1380.
    • (1998) Neuropharmacology , vol.37 , pp. 1369-1380
    • Cull-Candy, S.G.1    Brickley, S.G.2    Misra, C.3    Feldmeyer, D.4    Momiyama, A.5    Farrant, M.6
  • 54
    • 0014965714 scopus 로고
    • Strychnine, glycine and vertebrate postsynaptic inhibition
    • Curtis, D. R. & Johnston, G. A. 1970 Strychnine, glycine and vertebrate postsynaptic inhibition. Nature 225, 1258-1259.
    • (1970) Nature , vol.225 , pp. 1258-1259
    • Curtis, D.R.1    Johnston, G.A.2
  • 55
    • 0004195588 scopus 로고
    • Actions of amino acids on the isolated hemisected spinal cord of the toad
    • Curtis, D. R., Phillis, J. W. & Watkins, J. C. 1961 Actions of amino acids on the isolated hemisected spinal cord of the toad. Br. J. Pharmacol. 16, 262-283.
    • (1961) Br. J. Pharmacol. , vol.16 , pp. 262-283
    • Curtis, D.R.1    Phillis, J.W.2    Watkins, J.C.3
  • 56
    • 0030052492 scopus 로고    scopus 로고
    • Glycine at the NMDA receptor in cat visual cortex: Saturation and changes with age
    • Czepita, D., Daw, N. W. & Reid, S. N. 1996 Glycine at the NMDA receptor in cat visual cortex: saturation and changes with age. J. Neurophysiol. 75, 311-317.
    • (1996) J. Neurophysiol. , vol.75 , pp. 311-317
    • Czepita, D.1    Daw, N.W.2    Reid, S.N.3
  • 57
    • 0027185859 scopus 로고
    • L-Glutamate may be the fast excitatory transmitter of Aplysia sensory neurons
    • Dale, N. & Kandel, E. R. 1993 L-Glutamate may be the fast excitatory transmitter of Aplysia sensory neurons. Proc. Natl Acad. Sci. USA 90, 7163-7167.
    • (1993) Proc. Natl Acad. Sci. USA , vol.90 , pp. 7163-7167
    • Dale, N.1    Kandel, E.R.2
  • 58
    • 0017264088 scopus 로고
    • Regional distribution and properties of the glycine cleavage system within the central nervous system of the rat: Evidence for an endogenous inhibitor during in vitro assay
    • Daly, E. C., Nadi, N. S. & Aprison, M. H. 1976 Regional distribution and properties of the glycine cleavage system within the central nervous system of the rat: evidence for an endogenous inhibitor during in vitro assay. J. Neurochem. 26, 179-185.
    • (1976) J. Neurochem. , vol.26 , pp. 179-185
    • Daly, E.C.1    Nadi, N.S.2    Aprison, M.H.3
  • 60
    • 0032429754 scopus 로고    scopus 로고
    • Glycine and N-methyl-D-aspartate receptors: Physiological significance and possible therapeutic applications
    • Danysz, W. & Parsons, A. C. 1998 Glycine and N-methyl-D-aspartate receptors: physiological significance and possible therapeutic applications. Pharmacol. Rev. 50, 597-664.
    • (1998) Pharmacol. Rev. , vol.50 , pp. 597-664
    • Danysz, W.1    Parsons, A.C.2
  • 61
    • 0024985367 scopus 로고
    • 3H]D-serine labels strychnine-insensitive glycine recognition sites of rat central nervous system
    • 3H]D-serine labels strychnine-insensitive glycine recognition sites of rat central nervous system. Life Sci. 46, 155-164.
    • (1990) Life Sci. , vol.46 , pp. 155-164
    • Danysz, W.1    Fadda, E.2    Wroblewski, J.T.3    Costa, E.4
  • 62
    • 0018184786 scopus 로고
    • High-affinity glycine binding sites in rat CNS: Regional variation and strychnine sensitivity
    • DeFeudis, F. V., Orensanz Munoz, L. M. & Fando, J. L. 1978 High-affinity glycine binding sites in rat CNS: regional variation and strychnine sensitivity. Gen. Pharmacol. 9, 171-176.
    • (1978) Gen. Pharmacol. , vol.9 , pp. 171-176
    • DeFeudis, F.V.1    Orensanz Munoz, L.M.2    Fando, J.L.3
  • 64
    • 0014490436 scopus 로고
    • The oxidation of glycine by D-amino acid oxidase in extracts of mammalian central nervous tissue
    • De Marchi, W. J. & Johnston, G. A. 1969 The oxidation of glycine by D-amino acid oxidase in extracts of mammalian central nervous tissue. J. Neurochem. 16, 355-361.
    • (1969) J. Neurochem. , vol.16 , pp. 355-361
    • De Marchi, W.J.1    Johnston, G.A.2
  • 65
    • 0037195093 scopus 로고    scopus 로고
    • Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine
    • De Miranda, J., Panizzutti, R., Foltyn, V. N. & Wolosker, H. 2002 Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine. Proc. Natl Acad. Sci. USA 99, 14 542-14 547.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 14542-14547
    • De Miranda, J.1    Panizzutti, R.2    Foltyn, V.N.3    Wolosker, H.4
  • 66
    • 0031939465 scopus 로고    scopus 로고
    • NMDA-coupled periaqueductal gray glycine receptors modulate anxioselective drug effects on plus-maze performance
    • De Souza, M. M., Schenberg, L. C. & de Padua Carobrez, A. 1998 NMDA-coupled periaqueductal gray glycine receptors modulate anxioselective drug effects on plus-maze performance. Behav. Brain Res. 90, 157-165.
    • (1998) Behav. Brain Res. , vol.90 , pp. 157-165
    • De Souza, M.M.1    Schenberg, L.C.2    De Padua Carobrez, A.3
  • 68
    • 0023374279 scopus 로고
    • Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study
    • Dupont, J. L., Gardette, R. & Crepel, F. 1987 Postnatal development of the chemosensitivity of rat cerebellar Purkinje cells to excitatory amino acids. An in vitro study. Brain Res. 431, 59-68.
    • (1987) Brain Res. , vol.431 , pp. 59-68
    • Dupont, J.L.1    Gardette, R.2    Crepel, F.3
  • 69
    • 0029761783 scopus 로고    scopus 로고
    • Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene
    • Ebralidze, A. K., Rossi, D. J., Tonegawa, S. & Slater, N. T. 1996 Modification of NMDA receptor channels and synaptic transmission by targeted disruption of the NR2C gene. J. Neurosci. 16, 5014-5025.
    • (1996) J. Neurosci. , vol.16 , pp. 5014-5025
    • Ebralidze, A.K.1    Rossi, D.J.2    Tonegawa, S.3    Slater, N.T.4
  • 70
    • 0025949567 scopus 로고
    • Actions of D-cycloserine at the N-methyl-D-aspartate-associated glycine receptor site in vivo
    • Emmett, M. R., Mick, S. J., Cler, J. A., Rao, T. S., Iyengar, S. & Wood, P. L. 1991 Actions of D-cycloserine at the N-methyl-D-aspartate-associated glycine receptor site in vivo. Neuropharmacology 30, 1167-1171.
    • (1991) Neuropharmacology , vol.30 , pp. 1167-1171
    • Emmett, M.R.1    Mick, S.J.2    Cler, J.A.3    Rao, T.S.4    Iyengar, S.5    Wood, P.L.6
  • 71
    • 2942721689 scopus 로고
    • Cycloserine, a new antibiotic in the treatment of human pulmonary tuberculosis: A preliminary report
    • Epstein, I., Nair, K. G. & Boyd, L. J. 1955 Cycloserine, a new antibiotic in the treatment of human pulmonary tuberculosis: a preliminary report. Antibiot. Med. 1, 30.
    • (1955) Antibiot. Med. , vol.1 , pp. 30
    • Epstein, I.1    Nair, K.G.2    Boyd, L.J.3
  • 72
    • 0033166235 scopus 로고    scopus 로고
    • Active NMDA glutamate receptors are expressed by mammalian osteoclasts
    • Espinosa, L., Itzstein, C., Cheynel, H., Delmas, P. D. & Chenu, C. 1999 Active NMDA glutamate receptors are expressed by mammalian osteoclasts. J. Physiol. 518, 47-53.
    • (1999) J. Physiol. , vol.518 , pp. 47-53
    • Espinosa, L.1    Itzstein, C.2    Cheynel, H.3    Delmas, P.D.4    Chenu, C.5
  • 73
    • 0034058017 scopus 로고    scopus 로고
    • Placebo-controlled trial of glycine added to clozapine in schizophrenia
    • Evins, A. E., Fitzgerald, S. M., Wine, L., Rosselli, R. & Goff, D. C. 2000 Placebo-controlled trial of glycine added to clozapine in schizophrenia. Am. J. Psychiatry 157, 826-828.
    • (2000) Am. J. Psychiatry , vol.157 , pp. 826-828
    • Evins, A.E.1    Fitzgerald, S.M.2    Wine, L.3    Rosselli, R.4    Goff, D.C.5
  • 74
    • 0028295715 scopus 로고
    • NMDA-receptor channel diversity in the developing cerebellum
    • Farrant, M., Feldmeyer, D., Takahashi, T. & Cull-Candy, S. G. 1994 NMDA-receptor channel diversity in the developing cerebellum. Nature 368, 335-339.
    • (1994) Nature , vol.368 , pp. 335-339
    • Farrant, M.1    Feldmeyer, D.2    Takahashi, T.3    Cull-Candy, S.G.4
  • 75
    • 0032416263 scopus 로고    scopus 로고
    • Functional and immunocytochemical identification of glutamate autoreceptors of an NMDA type in crayfish neuromuscular junction
    • Feinstein, N., Parnas, D., Parnas, H., Dudel, J. & Parnas, I. 1998 Functional and immunocytochemical identification of glutamate autoreceptors of an NMDA type in crayfish neuromuscular junction. J. Neurophysiol. 80, 2893-2899.
    • (1998) J. Neurophysiol. , vol.80 , pp. 2893-2899
    • Feinstein, N.1    Parnas, D.2    Parnas, H.3    Dudel, J.4    Parnas, I.5
  • 76
    • 33544461370 scopus 로고    scopus 로고
    • The Venus flytrap of periplasmic binding proteins: An ancient protein module present in multiple drug receptors
    • DOI 1208/PS010202
    • Felder, C. B., Graul, R. C., Lee, A. Y., Merkle, H. P. & Sadee, W. 1999 The Venus flytrap of periplasmic binding proteins: an ancient protein module present in multiple drug receptors. AAPS Pharm. Sci. 1, E2, 1-10. (DOI 1208/PS010202.)
    • (1999) AAPS Pharm. Sci. , vol.1
    • Felder, C.B.1    Graul, R.C.2    Lee, A.Y.3    Merkle, H.P.4    Sadee, W.5
  • 77
    • 0021797084 scopus 로고
    • Free and conjugated amino acids in human CSF: Influence of age and sex
    • Ferraro, T. N. & Hare, T. A. 1985 Free and conjugated amino acids in human CSF: influence of age and sex. Brain Res. 338, 53-60.
    • (1985) Brain Res. , vol.338 , pp. 53-60
    • Ferraro, T.N.1    Hare, T.A.2
  • 78
    • 0015408522 scopus 로고
    • Animal evolution in the field of synaptic substances
    • Fischer, H. 1972 Animal evolution in the field of synaptic substances. Naturwissenschaften 59, 425-435.
    • (1972) Naturwissenschaften , vol.59 , pp. 425-435
    • Fischer, H.1
  • 80
    • 0038606161 scopus 로고    scopus 로고
    • Structural model of the NMDA receptor glycine site probed by site-directed chemical coupling
    • Foucaud, B., Laube, B., Schemm, R., Kreimeyer, A., Goeldner, M. & Betz, H. 2003 Structural model of the NMDA receptor glycine site probed by site-directed chemical coupling. J. Biol. Chem. 278, 24 011-24 017.
    • (2003) J. Biol. Chem. , vol.278 , pp. 24011-24017
    • Foucaud, B.1    Laube, B.2    Schemm, R.3    Kreimeyer, A.4    Goeldner, M.5    Betz, H.6
  • 81
    • 0032870992 scopus 로고    scopus 로고
    • Glutamate is a fast excitatory transmitter at some buccal neuromuscular synapses in Aplysia
    • Fox, L. E. & Lloyd, P. E. 1999 Glutamate is a fast excitatory transmitter at some buccal neuromuscular synapses in Aplysia. J. Neurophysiol. 82, 1477-1488.
    • (1999) J. Neurophysiol. , vol.82 , pp. 1477-1488
    • Fox, L.E.1    Lloyd, P.E.2
  • 83
    • 0038037859 scopus 로고    scopus 로고
    • Mechanisms of activation, inhibition and specificity: Crystal structures of the NMDA receptor NR1 ligand-binding core
    • Furukawa, H. & Gouaux, E. 2003 Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core. EMBO J. 22, 2873-2885.
    • (2003) EMBO J. , vol.22 , pp. 2873-2885
    • Furukawa, H.1    Gouaux, E.2
  • 85
    • 0038257594 scopus 로고
    • A glia-neural theory of brain function
    • Galambos, R. 1961 A glia-neural theory of brain function. Proc. Natl Acad. Sci. USA 47, 129-136.
    • (1961) Proc. Natl Acad. Sci. USA , vol.47 , pp. 129-136
    • Galambos, R.1
  • 86
    • 0029145991 scopus 로고
    • Excitatory amino acid receptors in glia: Different subtypes for distinct functions?
    • Gallo, V. & Russell, J. T. 1995 Excitatory amino acid receptors in glia: different subtypes for distinct functions? J. Neurosci. Res. 42, 1-8.
    • (1995) J. Neurosci. Res. , vol.42 , pp. 1-8
    • Gallo, V.1    Russell, J.T.2
  • 87
    • 0028450078 scopus 로고
    • Excitatory amino acid receptors in glial progenitor cells: Molecular and functional properties
    • Gallo, V., Patneau, D. K., Mayer, M. L. & Vaccarino, F. M. 1994 Excitatory amino acid receptors in glial progenitor cells: molecular and functional properties. Glia 11, 94-101.
    • (1994) Glia , vol.11 , pp. 94-101
    • Gallo, V.1    Patneau, D.K.2    Mayer, M.L.3    Vaccarino, F.M.4
  • 88
    • 0016278916 scopus 로고
    • The nature of D-serine-induced nephrotoxicity
    • Ganote, C. E., Peterson, D. R. & Carone, F. A. 1974 The nature of D-serine-induced nephrotoxicity. Am. J. Pathol. 77, 269-282.
    • (1974) Am. J. Pathol. , vol.77 , pp. 269-282
    • Ganote, C.E.1    Peterson, D.R.2    Carone, F.A.3
  • 89
    • 0023485707 scopus 로고
    • Selective loss of Purkinje and granule cell responsiveness to N-methyl-D-aspartate in rat cerebellum during development
    • Garthwaite, G., Yamini Jr, B. & Garthwaite, J. 1987 Selective loss of Purkinje and granule cell responsiveness to N-methyl-D-aspartate in rat cerebellum during development. Brain Res. 433, 288-292.
    • (1987) Brain Res. , vol.433 , pp. 288-292
    • Garthwaite, G.1    Yamini Jr., B.2    Garthwaite, J.3
  • 90
    • 85047694372 scopus 로고
    • Subcellular distribution of D-amino acid oxidase and catalase in rat brain
    • Gaunt, G. L. & de Duve, C. 1976 Subcellular distribution of D-amino acid oxidase and catalase in rat brain. J. Neurochem. 26, 749-759.
    • (1976) J. Neurochem. , vol.26 , pp. 749-759
    • Gaunt, G.L.1    De Duve, C.2
  • 92
    • 0034843738 scopus 로고    scopus 로고
    • The emerging role of glutamate in the pathophysiology and treatment of schizophrenia
    • Goff, D. C. & Coyle, J. T. 2001 The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. Am. J. Psychiatry 158, 1367-1377.
    • (2001) Am. J. Psychiatry , vol.158 , pp. 1367-1377
    • Goff, D.C.1    Coyle, J.T.2
  • 93
    • 0029116094 scopus 로고
    • Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia
    • Goff, D. C., Tsai, G., Manoach, D. S. & Coyle, J. T. 1995 Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia. Am. J. Psychiatry 152, 1213-1215.
    • (1995) Am. J. Psychiatry , vol.152 , pp. 1213-1215
    • Goff, D.C.1    Tsai, G.2    Manoach, D.S.3    Coyle, J.T.4
  • 94
    • 0013958688 scopus 로고
    • D-Amino acid oxidase in brain: Distribution in several species and inhibition by pentobarbitone
    • Goldstein, D. B. 1966 D-Amino acid oxidase in brain: distribution in several species and inhibition by pentobarbitone. J. Neurochem. 13, 1011-1016.
    • (1966) J. Neurochem. , vol.13 , pp. 1011-1016
    • Goldstein, D.B.1
  • 95
    • 0029797116 scopus 로고    scopus 로고
    • Catecholamine phenotyping: Clues to the diagnosis, treatment, and pathophysiology of neurogenetic disorders
    • Goldstein, D. S., Lenders, J. W., Kaler, S. G. & Eisenhofer, G. 1996 Catecholamine phenotyping: clues to the diagnosis, treatment, and pathophysiology of neurogenetic disorders. J. Neurochem. 67, 1781-1790.
    • (1996) J. Neurochem. , vol.67 , pp. 1781-1790
    • Goldstein, D.S.1    Lenders, J.W.2    Kaler, S.G.3    Eisenhofer, G.4
  • 96
    • 0032924127 scopus 로고    scopus 로고
    • The neuropathology of schizophrenia. A critical review of the data and their interpretation
    • Harrison, P. J. 1999 The neuropathology of schizophrenia. A critical review of the data and their interpretation. Brain 122, 593-624.
    • (1999) Brain , vol.122 , pp. 593-624
    • Harrison, P.J.1
  • 97
    • 0037308528 scopus 로고    scopus 로고
    • Genes for schizophrenia? Recent findings and their pathophysiological implications
    • Harrison, P. J. & Owen, M. J. 2003 Genes for schizophrenia? Recent findings and their pathophysiological implications. Lancet 361, 417-419.
    • (2003) Lancet , vol.361 , pp. 417-419
    • Harrison, P.J.1    Owen, M.J.2
  • 98
    • 0037319166 scopus 로고    scopus 로고
    • Excitatory amino acid receptors of the electrosensory system: The NR1/NR2B N-methyl-D-aspartate receptor
    • Harvey-Girard, E. & Dunn, R. J. 2003 Excitatory amino acid receptors of the electrosensory system: the NR1/NR2B N-methyl-D-aspartate receptor. J. Neurophysiol. 89, 822-832.
    • (2003) J. Neurophysiol. , vol.89 , pp. 822-832
    • Harvey-Girard, E.1    Dunn, R.J.2
  • 99
    • 0037111279 scopus 로고    scopus 로고
    • Effect of the intracerebroventricular and systemic administration of L-serine on the concentrations of D- and L-serine in several brain areas and periphery of rat
    • Hashimoto, A. 2002 Effect of the intracerebroventricular and systemic administration of L-serine on the concentrations of D- and L-serine in several brain areas and periphery of rat. Brain Res. 955, 214-220.
    • (2002) Brain Res. , vol.955 , pp. 214-220
    • Hashimoto, A.1
  • 100
    • 0030850891 scopus 로고    scopus 로고
    • Free D-aspartate and D-serine in the mammalian brain and periphery
    • Hashimoto, A. & Oka, T. 1997 Free D-aspartate and D-serine in the mammalian brain and periphery. Prog. Neurobiol. 52, 325-353.
    • (1997) Prog. Neurobiol. , vol.52 , pp. 325-353
    • Hashimoto, A.1    Oka, T.2
  • 102
    • 0027473657 scopus 로고
    • Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging
    • Hashimoto, A., Nishikawa, T., Oka, T. & Takahashi, K. 1993a Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging. J. Neurochem. 60, 783-786.
    • (1993) J. Neurochem. , vol.60 , pp. 783-786
    • Hashimoto, A.1    Nishikawa, T.2    Oka, T.3    Takahashi, K.4
  • 103
    • 0027159584 scopus 로고
    • Free D-serine, D-aspartate and D-alanine in central nervous system and serum in mutant mice lacking D-amino acid oxidase
    • Hashimoto, A., Nishikawa, T., Konno, R., Niwa, A., Yasumura, Y., Oka, T. & Takahashi, K. 1993b Free D-serine, D-aspartate and D-alanine in central nervous system and serum in mutant mice lacking D-amino acid oxidase. Neurosci. Lett. 152, 33-36.
    • (1993) Neurosci. Lett. , vol.152 , pp. 33-36
    • Hashimoto, A.1    Nishikawa, T.2    Konno, R.3    Niwa, A.4    Yasumura, Y.5    Oka, T.6    Takahashi, K.7
  • 104
    • 0027267388 scopus 로고
    • Embryonic development and postnatal changes in free D-aspartate and D-serine in the human prefrontal cortex
    • Hashimoto, A. (and 11 others) 1993c Embryonic development and postnatal changes in free D-aspartate and D-serine in the human prefrontal cortex. J. Neurochem. 61, 348-351.
    • (1993) J. Neurochem. , vol.61 , pp. 348-351
    • Hashimoto, A.1
  • 105
    • 0029025347 scopus 로고
    • Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis
    • Hashimoto, A., Oka, T. & Nishikawa, T. 1995a Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis. Neuroscience 66, 635-643.
    • (1995) Neuroscience , vol.66 , pp. 635-643
    • Hashimoto, A.1    Oka, T.2    Nishikawa, T.3
  • 106
    • 0029156742 scopus 로고
    • Anatomical distribution and postnatal changes in endogenous free D-aspartate and D-serine in rat brain and periphery
    • Hashimoto, A., Oka, T. & Nishikawa, T. 1995b Anatomical distribution and postnatal changes in endogenous free D-aspartate and D-serine in rat brain and periphery. Eur. J. Neurosci. 7, 1657-1663.
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 1657-1663
    • Hashimoto, A.1    Oka, T.2    Nishikawa, T.3
  • 107
    • 0033669106 scopus 로고    scopus 로고
    • Effects of N-methyl-D-aspartate, kainate or veratridine on extracellular concentrations of free D-serine and L-glutamate in rat striatum: An in vivo microdialysis study
    • Hashimoto, A., Kanda, J. & Oka, T. 2000 Effects of N-methyl-D-aspartate, kainate or veratridine on extracellular concentrations of free D-serine and L-glutamate in rat striatum: an in vivo microdialysis study. Brain Res. Bull. 53, 347-351.
    • (2000) Brain Res. Bull. , vol.53 , pp. 347-351
    • Hashimoto, A.1    Kanda, J.2    Oka, T.3
  • 108
    • 0037977113 scopus 로고    scopus 로고
    • Decreased serum levels of D-serine in patients with schizophrenia: Evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia
    • Hashimoto, K. (and 11 others) 2003 Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia. Arch. Gen. Psychiatry 60, 572-576.
    • (2003) Arch. Gen. Psychiatry , vol.60 , pp. 572-576
    • Hashimoto, K.1
  • 112
    • 0029081932 scopus 로고
    • Recordings of glutamategated ion channels in outside-out patches from Drosophila larval muscle
    • Heckmann, M. & Dudel, J. 1995 Recordings of glutamategated ion channels in outside-out patches from Drosophila larval muscle. Neurosci. Lett. 196, 53-56.
    • (1995) Neurosci. Lett. , vol.196 , pp. 53-56
    • Heckmann, M.1    Dudel, J.2
  • 114
    • 0036184549 scopus 로고    scopus 로고
    • Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia
    • Heresco-Levy, U., Ermilov, M., Shimoni, J., Shapira, B., Silipo, G. & Javitt, D. C. 2002 Placebo-controlled trial of D-cycloserine added to conventional neuroleptics, olanzapine, or risperidone in schizophrenia. Am. J. Psychiatry 159, 480-482.
    • (2002) Am. J. Psychiatry , vol.159 , pp. 480-482
    • Heresco-Levy, U.1    Ermilov, M.2    Shimoni, J.3    Shapira, B.4    Silipo, G.5    Javitt, D.C.6
  • 115
    • 0023634852 scopus 로고
    • Mismatches between neurotransmitter and receptor localizations in brain: Observations and implications
    • Herkenham, M. 1987 Mismatches between neurotransmitter and receptor localizations in brain: observations and implications. Neuroscience 23, 1-38.
    • (1987) Neuroscience , vol.23 , pp. 1-38
    • Herkenham, M.1
  • 116
    • 0029893942 scopus 로고    scopus 로고
    • The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: Identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region
    • Hirai, H., Kirsch, J., Laube, B., Betz, H. & Kuhse, J. 1996 The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region. Proc. Natl Acad. Sci. USA 93, 6031-6036.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 6031-6036
    • Hirai, H.1    Kirsch, J.2    Laube, B.3    Betz, H.4    Kuhse, J.5
  • 117
    • 0023445118 scopus 로고
    • Localization of D-amino acid oxidase in Bergmann glial cells and astrocytes of rat cerebellum
    • Horiike, K., Tojo, H., Arai, R., Yamano, T., Nozaki, M. & Maeda, T. 1987 Localization of D-amino acid oxidase in Bergmann glial cells and astrocytes of rat cerebellum. Brain Res. Bull. 19, 587-596.
    • (1987) Brain Res. Bull. , vol.19 , pp. 587-596
    • Horiike, K.1    Tojo, H.2    Arai, R.3    Yamano, T.4    Nozaki, M.5    Maeda, T.6
  • 118
    • 0028176862 scopus 로고
    • D-Amino-acid oxidase is confined to the lower brain stem and cerebellum in rat brain: Regional differentiation of astrocytes
    • Horiike, K., Tojo, H., Arai, R., Nozaki, M. & Maeda, T. 1994 D-Amino-acid oxidase is confined to the lower brain stem and cerebellum in rat brain: regional differentiation of astrocytes. Brain Res. 652, 297-303.
    • (1994) Brain Res. , vol.652 , pp. 297-303
    • Horiike, K.1    Tojo, H.2    Arai, R.3    Nozaki, M.4    Maeda, T.5
  • 119
    • 0035961626 scopus 로고    scopus 로고
    • Distribution of D-amino acid oxidase and D-serine in vertebrate brains
    • Horiike, K., Ishida, T., Tanaka, H. & Arai, R. 2001 Distribution of D-amino acid oxidase and D-serine in vertebrate brains. J. Mol. Catal. B Enzym. 12, 37-41.
    • (2001) J. Mol. Catal. B Enzym. , vol.12 , pp. 37-41
    • Horiike, K.1    Ishida, T.2    Tanaka, H.3    Arai, R.4
  • 123
    • 0032493660 scopus 로고    scopus 로고
    • Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit
    • Ivanovic, A., Reilander, H., Laube, B. & Kuhse, J. 1998 Expression and initial characterization of a soluble glycine binding domain of the N-methyl-D-aspartate receptor NR1 subunit. J. Biol. Chem. 273, 19 933-19 937.
    • (1998) J. Biol. Chem. , vol.273 , pp. 19933-19937
    • Ivanovic, A.1    Reilander, H.2    Laube, B.3    Kuhse, J.4
  • 124
    • 0021241921 scopus 로고
    • The Ferrier Lecture, 1983. Amino acids and peptides: Fast and slow chemical signals in the nervous system?
    • Iversen, L. L. 1984 The Ferrier Lecture, 1983. Amino acids and peptides: fast and slow chemical signals in the nervous system? Proc. R. Soc. Lond. B 221, 245-260.
    • (1984) Proc. R. Soc. Lond. B , vol.221 , pp. 245-260
    • Iversen, L.L.1
  • 126
    • 0036667177 scopus 로고    scopus 로고
    • Glycine modulators in schizophrenia
    • Javitt, D. C. 2002 Glycine modulators in schizophrenia. Curr. Opin. Investig. Drugs 3, 1067-1072.
    • (2002) Curr. Opin. Investig. Drugs , vol.3 , pp. 1067-1072
    • Javitt, D.C.1
  • 128
    • 0037150760 scopus 로고    scopus 로고
    • A novel alanine-insensitive D-serine transporter in rat brain synaptosomal membranes
    • Javitt, D. C., Balla, A. & Sershen, H. 2002 A novel alanine-insensitive D-serine transporter in rat brain synaptosomal membranes. Brain Res. 941, 146-149.
    • (2002) Brain Res. , vol.941 , pp. 146-149
    • Javitt, D.C.1    Balla, A.2    Sershen, H.3
  • 129
    • 0023091647 scopus 로고
    • Glycine potentiates the NMDA response in cultured mouse brain neurons
    • Johnson, J. W. & Ascher, P. 1987 Glycine potentiates the NMDA response in cultured mouse brain neurons. Nature 325, 529-531.
    • (1987) Nature , vol.325 , pp. 529-531
    • Johnson, J.W.1    Ascher, P.2
  • 130
    • 0029902542 scopus 로고    scopus 로고
    • Developmental expression of the glycine transporters GLYT1 and GLYT2 in mouse brain
    • Jursky, F. & Nelson, N. 1996 Developmental expression of the glycine transporters GLYT1 and GLYT2 in mouse brain. J. Neurochem. 67, 336-344.
    • (1996) J. Neurochem. , vol.67 , pp. 336-344
    • Jursky, F.1    Nelson, N.2
  • 131
    • 0034234496 scopus 로고    scopus 로고
    • Critical period for activity-dependent synapse elimination in developing cerebellum
    • Kakizawa, S., Yamasaki, M., Watanabe, M. & Kano, M. 2000 Critical period for activity-dependent synapse elimination in developing cerebellum. J. Neurosci. 20, 4954-4961.
    • (2000) J. Neurosci. , vol.20 , pp. 4954-4961
    • Kakizawa, S.1    Yamasaki, M.2    Watanabe, M.3    Kano, M.4
  • 132
    • 0037974527 scopus 로고    scopus 로고
    • The putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of carbon and nitrogen metabolism in Arabidopsis thaliana
    • Kang, J. & Turano, F. J. 2003 The putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of carbon and nitrogen metabolism in Arabidopsis thaliana. Proc. Natl Acad. Sci. USA 100, 6872-6877.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 6872-6877
    • Kang, J.1    Turano, F.J.2
  • 133
    • 0025858956 scopus 로고
    • Immunochemical relationship of D-amino acid oxidases in various tissues and animals
    • Katagiri, M., Tojo, H., Horiike, K. & Yamano, T. 1991 Immunochemical relationship of D-amino acid oxidases in various tissues and animals. Comp. Biochem. Physiol. B 99, 345-350.
    • (1991) Comp. Biochem. Physiol. B , vol.99 , pp. 345-350
    • Katagiri, M.1    Tojo, H.2    Horiike, K.3    Yamano, T.4
  • 134
    • 0035961624 scopus 로고    scopus 로고
    • D-Aspartate oxidase and free acidic D-amino acids in lower vertebrates
    • Kera, Y., Watanabe, T., Kimihiko, S., Nagasaki, H. & Yamada, R. 2001 D-Aspartate oxidase and free acidic D-amino acids in lower vertebrates. J. Mol. Catal. B 12, 121-129.
    • (2001) J. Mol. Catal. B , vol.12 , pp. 121-129
    • Kera, Y.1    Watanabe, T.2    Kimihiko, S.3    Nagasaki, H.4    Yamada, R.5
  • 135
    • 0034212705 scopus 로고    scopus 로고
    • Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site
    • Kew, J. N. (and 14 others) 2000 Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site. J. Neurosci. 20, 4037-4049.
    • (2000) J. Neurosci. , vol.20 , pp. 4037-4049
    • Kew, J.N.1
  • 136
    • 0019781152 scopus 로고
    • Determination of the equilibrium dissociation constants and number of glycine binding sites in several areas of the rat central nervous system, using a sodium-independent system
    • Kishimoto, H., Simon, J. R. & Aprison, M. H. 1981 Determination of the equilibrium dissociation constants and number of glycine binding sites in several areas of the rat central nervous system, using a sodium-independent system. J. Neurochem. 37, 1015-1024.
    • (1981) J. Neurochem. , vol.37 , pp. 1015-1024
    • Kishimoto, H.1    Simon, J.R.2    Aprison, M.H.3
  • 137
    • 0023754192 scopus 로고
    • Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes
    • Kleckner, N. W. & Dingledine, R. 1988 Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes. Science 241, 835-837.
    • (1988) Science , vol.241 , pp. 835-837
    • Kleckner, N.W.1    Dingledine, R.2
  • 139
    • 0021284582 scopus 로고
    • Serine uptake by luminal and basolateral membrane vesicles from rabbit kidney
    • Kragh-Hansen, U. & Sheikh, M. I. 1984 Serine uptake by luminal and basolateral membrane vesicles from rabbit kidney. J. Physiol. 354, 55-67.
    • (1984) J. Physiol. , vol.354 , pp. 55-67
    • Kragh-Hansen, U.1    Sheikh, M.I.2
  • 140
    • 0038334574 scopus 로고    scopus 로고
    • Functional NMDA receptor subtype 2B is expressed in astrocytes after ischemia in vivo and anoxia in vitro
    • Krebs, C., Fernandes, H. B., Sheldon, C., Raymond, L. A. & Baimbridge, K. G. 2003 Functional NMDA receptor subtype 2B is expressed in astrocytes after ischemia in vivo and anoxia in vitro. J. Neurosci. 23, 3364-3372.
    • (2003) J. Neurosci. , vol.23 , pp. 3364-3372
    • Krebs, C.1    Fernandes, H.B.2    Sheldon, C.3    Raymond, L.A.4    Baimbridge, K.G.5
  • 141
    • 0001062020 scopus 로고
    • Metabolism of amino-acids. III. Deamination of amino acids
    • Krebs, H. A. 1935 Metabolism of amino-acids. III. Deamination of amino acids. Biochem. J. 29, 1620-1643.
    • (1935) Biochem. J. , vol.29 , pp. 1620-1643
    • Krebs, H.A.1
  • 142
    • 2942703136 scopus 로고
    • The D- and L-amino-acid oxidases
    • Krebs, H. A. 1948 The D- and L-amino-acid oxidases. Biochem. Soc. Symp. 1, 2-18.
    • (1948) Biochem. Soc. Symp. , vol.1 , pp. 2-18
    • Krebs, H.A.1
  • 143
    • 0025215910 scopus 로고
    • Transient sensitivity of rat cerebellar Purkinje cells to N-methyl-D-aspartate during development. A voltage clamp study in in vitro slices
    • Krupa, M. & Crepel, F. 1990 Transient sensitivity of rat cerebellar Purkinje cells to N-methyl-D-aspartate during development. A voltage clamp study in in vitro slices. Eur. J. Neurosci. 2, 312-316.
    • (1990) Eur. J. Neurosci. , vol.2 , pp. 312-316
    • Krupa, M.1    Crepel, F.2
  • 144
    • 0032580152 scopus 로고    scopus 로고
    • A molecular timescale for vertebrate evolution
    • Kumar, S. & Hedges, S. B. 1998 A molecular timescale for vertebrate evolution. Nature 392, 917-920.
    • (1998) Nature , vol.392 , pp. 917-920
    • Kumar, S.1    Hedges, S.B.2
  • 145
    • 0029005597 scopus 로고
    • Free D-serine in post-mortem brains and spinal cords of individuals with and without neuropsychiatric diseases
    • Kumashiro, S., Hashimoto, A. & Nishikawa, T. 1995 Free D-serine in post-mortem brains and spinal cords of individuals with and without neuropsychiatric diseases. Brain Res. 681, 117-125.
    • (1995) Brain Res. , vol.681 , pp. 117-125
    • Kumashiro, S.1    Hashimoto, A.2    Nishikawa, T.3
  • 146
    • 0028284469 scopus 로고
    • Mutational analysis of the glycine-binding site of the NMDA receptor: Structural similarity with bacterial amino acid-binding proteins
    • Kuryatov, A., Laube, B., Betz, H. & Kuhse, J. 1994 Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins. Neuron 12, 1291-1300.
    • (1994) Neuron , vol.12 , pp. 1291-1300
    • Kuryatov, A.1    Laube, B.2    Betz, H.3    Kuhse, J.4
  • 147
    • 0029583151 scopus 로고
    • Molecular dissection of the agonist binding site of an AMPA receptor
    • Kuusinen, A., Arvola, M. & Keinanen, K. 1995 Molecular dissection of the agonist binding site of an AMPA receptor. EMBO J. 14, 6327-6332.
    • (1995) EMBO J. , vol.14 , pp. 6327-6332
    • Kuusinen, A.1    Arvola, M.2    Keinanen, K.3
  • 148
  • 150
    • 0024851760 scopus 로고
    • Do glia contribute to behaviour? A neuromodulatory review
    • Laming, P. R. 1989 Do glia contribute to behaviour? A neuromodulatory review. Comp. Biochem. Physiol. A 94, 555-568.
    • (1989) Comp. Biochem. Physiol. A , vol.94 , pp. 555-568
    • Laming, P.R.1
  • 151
    • 0032541434 scopus 로고    scopus 로고
    • AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition
    • Lampinen, M., Pentikainen, O., Johnson, M. S. & Keinanen, K. 1998 AMPA receptors and bacterial periplasmic amino acid-binding proteins share the ionic mechanism of ligand recognition. EMBO J. 17, 4704-4711.
    • (1998) EMBO J. , vol.17 , pp. 4704-4711
    • Lampinen, M.1    Pentikainen, O.2    Johnson, M.S.3    Keinanen, K.4
  • 152
    • 0030991790 scopus 로고    scopus 로고
    • Molecular determinants of agonist discrimination by NMDA receptor subunits: Analysis of the glutamate binding site on the NR2B subunit
    • Laube, B., Hirai, H., Sturgess, M., Betz, H. & Kuhse, J. 1997 Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit. Neuron 18, 493-503.
    • (1997) Neuron , vol.18 , pp. 493-503
    • Laube, B.1    Hirai, H.2    Sturgess, M.3    Betz, H.4    Kuhse, J.5
  • 153
    • 0032523002 scopus 로고    scopus 로고
    • Evidence for a tetrameric structure of recombinant NMDA receptors
    • Laube, B., Kuhse, J. & Betz, H. 1998 Evidence for a tetrameric structure of recombinant NMDA receptors. J. Neurosci. 18, 2954-2961.
    • (1998) J. Neurosci. , vol.18 , pp. 2954-2961
    • Laube, B.1    Kuhse, J.2    Betz, H.3
  • 154
    • 0026668152 scopus 로고
    • Astrocyte heterogeneity: Endogenous amino acid levels and release evoked by non-N-methyl-D-aspartate receptor agonists and by potassium-induced swelling in type-1 and type-2 astrocytes
    • Levi, G. & Patrizio, M. 1992 Astrocyte heterogeneity: endogenous amino acid levels and release evoked by non-N-methyl-D-aspartate receptor agonists and by potassium-induced swelling in type-1 and type-2 astrocytes. J. Neurochem. 58, 1943-1952.
    • (1992) J. Neurochem. , vol.58 , pp. 1943-1952
    • Levi, G.1    Patrizio, M.2
  • 155
    • 0027049815 scopus 로고
    • Release of exogenous and endogenous neurotransmitter amino acids from cultured astrocytes
    • Levi, G., Gallo, V. & Patrizio, M. 1992 Release of exogenous and endogenous neurotransmitter amino acids from cultured astrocytes. Prog. Brain Res. 94, 243-250.
    • (1992) Prog. Brain Res. , vol.94 , pp. 243-250
    • Levi, G.1    Gallo, V.2    Patrizio, M.3
  • 156
    • 0033842462 scopus 로고    scopus 로고
    • Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: Schizophrenia linkage collaborative group III
    • Levinson, D. F. (and 19 others) 2000 Multicenter linkage study of schizophrenia candidate regions on chromosomes 5q, 6q, 10p, and 13q: schizophrenia linkage collaborative group III. Am. J. Hum. Genet. 67, 652-663.
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 652-663
    • Levinson, D.F.1
  • 157
    • 84965088150 scopus 로고
    • Psychiatric and neurological reactions to cycloserine in the treatment of tuberculosis
    • Lewis, W. C., Calden, G., Thurston, R. & Gilson, W. E. 1957 Psychiatric and neurological reactions to cycloserine in the treatment of tuberculosis. Dis. Chest 32, 172-182.
    • (1957) Dis. Chest , vol.32 , pp. 172-182
    • Lewis, W.C.1    Calden, G.2    Thurston, R.3    Gilson, W.E.4
  • 158
    • 0031058747 scopus 로고    scopus 로고
    • Suggestive evidence for linkage of schizophrenia to markers on chromosome 13 in Caucasian but not Oriental populations
    • Lin, M. W., Sham, P., Hwu, H. G., Collier, D., Murray, R. & Powell, J. F. 1997 Suggestive evidence for linkage of schizophrenia to markers on chromosome 13 in Caucasian but not Oriental populations. Hum. Genet. 99, 417-420.
    • (1997) Hum. Genet. , vol.99 , pp. 417-420
    • Lin, M.W.1    Sham, P.2    Hwu, H.G.3    Collier, D.4    Murray, R.5    Powell, J.F.6
  • 160
    • 0015209755 scopus 로고
    • Unique high affinity uptake systems for glycine, glutamic and aspartic acids in central nervous tissue of the rat
    • Logan, W. J. & Snyder, S. H. 1971 Unique high affinity uptake systems for glycine, glutamic and aspartic acids in central nervous tissue of the rat. Nature 234, 297-299.
    • (1971) Nature , vol.234 , pp. 297-299
    • Logan, W.J.1    Snyder, S.H.2
  • 161
    • 0015723263 scopus 로고
    • Interconversion of glycine and serine in a synaptosome fraction isolated from the spinal cord, medulla oblongata, telencephalon, and cerebellum of the rat
    • McBride, W. J., Daly, E. & Aprison, M. H. 1973 Interconversion of glycine and serine in a synaptosome fraction isolated from the spinal cord, medulla oblongata, telencephalon, and cerebellum of the rat. J. Neurobiol. 4, 557-566.
    • (1973) J. Neurobiol. , vol.4 , pp. 557-566
    • McBride, W.J.1    Daly, E.2    Aprison, M.H.3
  • 162
    • 0036483593 scopus 로고    scopus 로고
    • The structure and function of glutamate receptor ion channels
    • Madden, D. R. 2002 The structure and function of glutamate receptor ion channels. Nature Rev. Neurosci. 3, 91-101.
    • (2002) Nature Rev. Neurosci. , vol.3 , pp. 91-101
    • Madden, D.R.1
  • 163
    • 0038222585 scopus 로고    scopus 로고
    • AMPA receptor trafficking and long-term potentiation
    • DOI 10.1098/rstb.2002.1233
    • Malinow, R. 2003 AMPA receptor trafficking and long-term potentiation. Phil. Trans. R. Soc. Lond. B 358, 707-714. (DOI 10.1098/rstb.2002.1233.)
    • (2003) Phil. Trans. R. Soc. Lond. B , vol.358 , pp. 707-714
    • Malinow, R.1
  • 164
    • 0029020761 scopus 로고
    • Functional comparison of D-serine and glycine in rodents: The effect on cloned NMDA receptors and the extracellular concentration
    • Matsui, T., Sekiguchi, M., Hashimoto, A., Tomita, U., Nishikawa, T. & Wada, K. 1995 Functional comparison of D-serine and glycine in rodents: the effect on cloned NMDA receptors and the extracellular concentration. J. Neurochem. 65, 454-458.
    • (1995) J. Neurochem. , vol.65 , pp. 454-458
    • Matsui, T.1    Sekiguchi, M.2    Hashimoto, A.3    Tomita, U.4    Nishikawa, T.5    Wada, K.6
  • 165
    • 0033649909 scopus 로고    scopus 로고
    • The molecular evolution of pyridoxal-5′-phosphate-dependent enzymes
    • Mehta, P. K. & Christen, P. 2000 The molecular evolution of pyridoxal-5′-phosphate-dependent enzymes. Adv. Enzymol. Relat. Areas Mol. Biol. 74, 129-184.
    • (2000) Adv. Enzymol. Relat. Areas Mol. Biol. , vol.74 , pp. 129-184
    • Mehta, P.K.1    Christen, P.2
  • 166
    • 0013085913 scopus 로고    scopus 로고
    • N-methyl-D-aspartate receptor-coupled glycine (b) receptors in the pathogenesis and treatment of schizophrenia: A critical review
    • Millan, M. J. 2002 N-methyl-D-aspartate receptor-coupled glycine (b) receptors in the pathogenesis and treatment of schizophrenia: a critical review. Curr. Drug Target CNS Neurol. Disord. 1, 191-213.
    • (2002) Curr. Drug Target CNS Neurol. Disord. , vol.1 , pp. 191-213
    • Millan, M.J.1
  • 167
    • 0034214430 scopus 로고    scopus 로고
    • Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells
    • Misra, C., Brickley, S. G., Wyllie, D. J. & Cull-Candy, S. G. 2000 Slow deactivation kinetics of NMDA receptors containing NR1 and NR2D subunits in rat cerebellar Purkinje cells. J. Physiol. 525, 299-305.
    • (2000) J. Physiol. , vol.525 , pp. 299-305
    • Misra, C.1    Brickley, S.G.2    Wyllie, D.J.3    Cull-Candy, S.G.4
  • 168
    • 0031931051 scopus 로고    scopus 로고
    • A novel metabolic communication between neurons and astrocytes: Non-essential amino acid L-serine released from astrocytes is essential for developing hippocampal neurons
    • Mitoma, J., Furuya, S. & Hirabayashi, Y. 1998 A novel metabolic communication between neurons and astrocytes: non-essential amino acid L-serine released from astrocytes is essential for developing hippocampal neurons. Neurosci. Res. 30, 195-199.
    • (1998) Neurosci. Res. , vol.30 , pp. 195-199
    • Mitoma, J.1    Furuya, S.2    Hirabayashi, Y.3
  • 169
    • 0033564631 scopus 로고    scopus 로고
    • Expression and characterization of a glycine-binding fragment of the N-methyl-D-aspartate receptor subunit NR1
    • Miyazaki, J., Nakanishi, S. & Jingami, H. 1999 Expression and characterization of a glycine-binding fragment of the N-methyl-D-aspartate receptor subunit NR1. Biochem. J. 340, 687-692.
    • (1999) Biochem. J. , vol.340 , pp. 687-692
    • Miyazaki, J.1    Nakanishi, S.2    Jingami, H.3
  • 170
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • Mohn, A. R., Gainetdinov, R. R., Caron, M. G. & Koller, B. H. 1999 Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98, 427-436.
    • (1999) Cell , vol.98 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 172
    • 0028343648 scopus 로고
    • Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
    • Monyer, H., Burnashev, N., Laurie, D. J., Sakmann, B. & Seeburg, P. H. 1994 Developmental and regional expression in the rat brain and functional properties of four NMDA receptors. Neuron 12, 529-540.
    • (1994) Neuron , vol.12 , pp. 529-540
    • Monyer, H.1    Burnashev, N.2    Laurie, D.J.3    Sakmann, B.4    Seeburg, P.H.5
  • 173
    • 0033499883 scopus 로고    scopus 로고
    • Immunocytochemical localization of D-amino acid oxidase in rat brain
    • Moreno, S., Nardacci, R., Cimini, A. & Ceru, M. P. 1999 Immunocytochemical localization of D-amino acid oxidase in rat brain. J. Neurocytol. 28, 169-185.
    • (1999) J. Neurocytol. , vol.28 , pp. 169-185
    • Moreno, S.1    Nardacci, R.2    Cimini, A.3    Ceru, M.P.4
  • 174
    • 0027457616 scopus 로고
    • NMDA-like receptors in the CNS of molluscs
    • Moroz, L. L., Gyori, J. & Salanki, J. 1993 NMDA-like receptors in the CNS of molluscs. Neuroreport 4, 201-204.
    • (1993) Neuroreport , vol.4 , pp. 201-204
    • Moroz, L.L.1    Gyori, J.2    Salanki, J.3
  • 176
    • 0016136578 scopus 로고
    • Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat
    • Mulder, A. H. & Snyder, S. H. 1974 Potassium-induced release of amino acids from cerebral cortex and spinal cord slices of the rat. Brain Res. 76, 297-308.
    • (1974) Brain Res. , vol.76 , pp. 297-308
    • Mulder, A.H.1    Snyder, S.H.2
  • 177
    • 0026450444 scopus 로고
    • A role for glial cells in activity-dependent central nervous plasticity? Review and hypothesis
    • Muller, C. M. 1992 A role for glial cells in activity-dependent central nervous plasticity? Review and hypothesis. Int. Rev. Neurobiol. 34, 215-281.
    • (1992) Int. Rev. Neurobiol. , vol.34 , pp. 215-281
    • Muller, C.M.1
  • 179
    • 0026714534 scopus 로고
    • Involvement of D-amino acid oxidase in elimination of D-serine in mouse brain
    • Nagata, Y. 1992 Involvement of D-amino acid oxidase in elimination of D-serine in mouse brain. Experientia 48, 753-755.
    • (1992) Experientia , vol.48 , pp. 753-755
    • Nagata, Y.1
  • 180
    • 0024529733 scopus 로고
    • Involvement of D-amino acid oxidase in elimination of free D-amino acids in mice
    • Nagata, Y., Konno, R., Yasumura, Y. & Akino, T. 1989 Involvement of D-amino acid oxidase in elimination of free D-amino acids in mice. Biochem. J. 257, 291-292.
    • (1989) Biochem. J. , vol.257 , pp. 291-292
    • Nagata, Y.1    Konno, R.2    Yasumura, Y.3    Akino, T.4
  • 181
    • 0027976595 scopus 로고
    • Distribution of free D-serine in vertebrate brains
    • Nagata, Y., Horiike, K. & Maeda, T. 1994 Distribution of free D-serine in vertebrate brains. Brain Res. 634, 291-295.
    • (1994) Brain Res. , vol.634 , pp. 291-295
    • Nagata, Y.1    Horiike, K.2    Maeda, T.3
  • 182
    • 0032704953 scopus 로고    scopus 로고
    • Occurrence of D-amino acids in a few archaea and dehydrogenase activities in hyperthermophile Pyrobaculum islandicum
    • Nagata, Y. (and 11 others) 1999 Occurrence of D-amino acids in a few archaea and dehydrogenase activities in hyperthermophile Pyrobaculum islandicum. Biochim. Biophys. Acta 1435, 160-166.
    • (1999) Biochim. Biophys. Acta , vol.1435 , pp. 160-166
    • Nagata, Y.1
  • 183
    • 0025221685 scopus 로고
    • A family of glutamate receptor genes: Evidence for the formation of heteromultimeric receptors with distinct channel properties
    • Nakanishi, N., Shneider, N. A. & Axel, R. 1990 A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties. Neuron 5, 569-581.
    • (1990) Neuron , vol.5 , pp. 569-581
    • Nakanishi, N.1    Shneider, N.A.2    Axel, R.3
  • 184
    • 0034733978 scopus 로고    scopus 로고
    • +-independent transporter for small neutral amino acids that transports D-serine with high affinity
    • +-independent transporter for small neutral amino acids that transports D-serine with high affinity. Neurosci. Lett. 287, 231-235.
    • (2000) Neurosci. Lett. , vol.287 , pp. 231-235
    • Nakauchi, J.1
  • 185
  • 186
    • 0036912112 scopus 로고    scopus 로고
    • Allosteric regulation of mouse brain serine racemase
    • Neidle, A. & Dunlop, D. S. 2002 Allosteric regulation of mouse brain serine racemase. Neurochem. Res. 27, 1719-1724.
    • (2002) Neurochem. Res. , vol.27 , pp. 1719-1724
    • Neidle, A.1    Dunlop, D.S.2
  • 187
    • 0013892496 scopus 로고
    • Distribution of D-amino acid oxidase in bovine and human nervous tissues
    • Neims, A. H., Zieverink, W. D. & Smilack, J. D. 1966 Distribution of D-amino acid oxidase in bovine and human nervous tissues. J. Neurochem. 13, 163-168.
    • (1966) J. Neurochem. , vol.13 , pp. 163-168
    • Neims, A.H.1    Zieverink, W.D.2    Smilack, J.D.3
  • 188
    • 0032079334 scopus 로고    scopus 로고
    • Extracellular space structure revealed by diffusion analysis
    • Nicholson, C. & Sykova, E. 1998 Extracellular space structure revealed by diffusion analysis. Trends Neurosci. 21, 207-215.
    • (1998) Trends Neurosci. , vol.21 , pp. 207-215
    • Nicholson, C.1    Sykova, E.2
  • 189
    • 0031435415 scopus 로고    scopus 로고
    • Glycine and D-serine decrease MK-801-induced hyperactivity in mice
    • Nilsson, M., Carlsson, A. & Carlsson, M. L. 1997 Glycine and D-serine decrease MK-801-induced hyperactivity in mice. J. Neural Transm. 104, 1195-1205.
    • (1997) J. Neural Transm. , vol.104 , pp. 1195-1205
    • Nilsson, M.1    Carlsson, A.2    Carlsson, M.L.3
  • 191
    • 0031019876 scopus 로고    scopus 로고
    • High extracellular glycine does not potentiate N-methyl-D-aspartate- evoked depolarization in vivo
    • Obrenovitch, T. P., Hardy, A. M. & Urenjak, J. 1997 High extracellular glycine does not potentiate N-methyl-D-aspartate-evoked depolarization in vivo. Brain Res. 746, 190-194.
    • (1997) Brain Res. , vol.746 , pp. 190-194
    • Obrenovitch, T.P.1    Hardy, A.M.2    Urenjak, J.3
  • 192
    • 0033117461 scopus 로고    scopus 로고
    • Catalytic promiscuity and the evolution of new enzymatic activities
    • O'Brien, P. J. & Herschlag, D. 1999 Catalytic promiscuity and the evolution of new enzymatic activities. Chem. Biol. 6, R91-R105.
    • (1999) Chem. Biol. , vol.6
    • O'Brien, P.J.1    Herschlag, D.2
  • 194
    • 0015612628 scopus 로고
    • Stereospecificity of blood-brain barrier permeability to amino acids
    • Oldendorf, W. H. 1973 Stereospecificity of blood-brain barrier permeability to amino acids. Am. J. Physiol. 224, 967-969.
    • (1973) Am. J. Physiol. , vol.224 , pp. 967-969
    • Oldendorf, W.H.1
  • 195
    • 0033360995 scopus 로고    scopus 로고
    • When less is more: Gene loss as an engine of evolutionary change
    • Olson, M. V. 1999 When less is more: gene loss as an engine of evolutionary change. Am. J. Hum. Genet. 64, 18-23.
    • (1999) Am. J. Hum. Genet. , vol.64 , pp. 18-23
    • Olson, M.V.1
  • 196
    • 17144450204 scopus 로고    scopus 로고
    • Identification of the amino acid subsets accounting for the ligand binding specificity of a glutamate receptor
    • Paas, Y., Eisenstein, M., Medevielle, F., Teichberg, V. I. & Devillers-Thiery, A. 1996 Identification of the amino acid subsets accounting for the ligand binding specificity of a glutamate receptor. Neuron 17, 979-990.
    • (1996) Neuron , vol.17 , pp. 979-990
    • Paas, Y.1    Eisenstein, M.2    Medevielle, F.3    Teichberg, V.I.4    Devillers-Thiery, A.5
  • 197
    • 0002449713 scopus 로고    scopus 로고
    • How well can molecular modelling predict the crystal structure: The case of the ligand-binding domain of glutamate receptors
    • Paas, Y., Devillers-Thiery, A., Teichberg, V. I., Changeux, J. P. & Eisenstein, M. 2000 How well can molecular modelling predict the crystal structure: the case of the ligand-binding domain of glutamate receptors. Trends Pharmacol. Sci. 21, 87-92.
    • (2000) Trends Pharmacol. Sci. , vol.21 , pp. 87-92
    • Paas, Y.1    Devillers-Thiery, A.2    Teichberg, V.I.3    Changeux, J.P.4    Eisenstein, M.5
  • 198
    • 0035942231 scopus 로고    scopus 로고
    • A new strategy to decrease N-methyl-D-aspartate (NMDA) receptor coactivation: Inhibition of D-serine synthesis by converting serine racemase into an eliminase
    • Panizzutti, R., De Miranda, J., Ribeiro, C. S., Engelender, S. & Wolosker, H. 2001 A new strategy to decrease N-methyl-D-aspartate (NMDA) receptor coactivation: inhibition of D-serine synthesis by converting serine racemase into an eliminase. Proc. Natl Acad. Sci. USA 98, 5294-5299.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 5294-5299
    • Panizzutti, R.1    De Miranda, J.2    Ribeiro, C.S.3    Engelender, S.4    Wolosker, H.5
  • 200
    • 0032814037 scopus 로고    scopus 로고
    • The subependymal layer in rodents: A site of structural plasticity and cell migration in the adult mammalian brain
    • Peretto, P., Merighi, A., Fasolo, A. & Bonfanti, L. 1999 The subependymal layer in rodents: a site of structural plasticity and cell migration in the adult mammalian brain. Brain Res. Bull. 49, 221-243.
    • (1999) Brain Res. Bull. , vol.49 , pp. 221-243
    • Peretto, P.1    Merighi, A.2    Fasolo, A.3    Bonfanti, L.4
  • 201
    • 0028087773 scopus 로고
    • The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1
    • Petralia, R. S., Wang, Y. X. & Wenthold, R. J. 1994a The NMDA receptor subunits NR2A and NR2B show histological and ultrastructural localization patterns similar to those of NR1. J. Neurosci. 14, 6102-6120.
    • (1994) J. Neurosci. , vol.14 , pp. 6102-6120
    • Petralia, R.S.1    Wang, Y.X.2    Wenthold, R.J.3
  • 202
    • 0028157362 scopus 로고
    • Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody
    • Petralia, R. S., Yokotani, N. & Wenthold, R. J. 1994b Light and electron microscope distribution of the NMDA receptor subunit NMDAR1 in the rat nervous system using a selective anti-peptide antibody. J. Neurosci. 14, 667-696.
    • (1994) J. Neurosci. , vol.14 , pp. 667-696
    • Petralia, R.S.1    Yokotani, N.2    Wenthold, R.J.3
  • 203
    • 0026076186 scopus 로고
    • An arthropod NMDA receptor
    • Pfeiffer-Linn, C. & Glantz, R. M. 1991 An arthropod NMDA receptor. Synapse 9, 35-42.
    • (1991) Synapse , vol.9 , pp. 35-42
    • Pfeiffer-Linn, C.1    Glantz, R.M.2
  • 206
    • 0032955821 scopus 로고    scopus 로고
    • Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia
    • Potkin, S. G., Jin, Y., Bunney, B. G., Costa, J. & Gulasekaram, B. 1999 Effect of clozapine and adjunctive high-dose glycine in treatment-resistant schizophrenia. Am. J. Psychiatry 156, 145-147.
    • (1999) Am. J. Psychiatry , vol.156 , pp. 145-147
    • Potkin, S.G.1    Jin, Y.2    Bunney, B.G.3    Costa, J.4    Gulasekaram, B.5
  • 207
    • 0028823737 scopus 로고
    • Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells
    • Priestley, T., Laughton, P., Myers, J., Le Bourdelles, B., Kerby, J. & Whiting, P. J. 1995 Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells. Mol. Phamacol. 48, 841-848.
    • (1995) Mol. Phamacol. , vol.48 , pp. 841-848
    • Priestley, T.1    Laughton, P.2    Myers, J.3    Le Bourdelles, B.4    Kerby, J.5    Whiting, P.J.6
  • 208
    • 0032695576 scopus 로고    scopus 로고
    • Glutamate-induced rise in cytosolic calcium concentration stimulates in vitro rates of juvenile hormone biosynthesis in corpus allatum of Diploptera punctata
    • Pszczolkowski, M. A., Lee, W. S., Liu, H. P. & Chiang, A. S. 1999 Glutamate-induced rise in cytosolic calcium concentration stimulates in vitro rates of juvenile hormone biosynthesis in corpus allatum of Diploptera punctata. Mol. Cell. Endocrinol 158, 163-171.
    • (1999) Mol. Cell. Endocrinol , vol.158 , pp. 163-171
    • Pszczolkowski, M.A.1    Lee, W.S.2    Liu, H.P.3    Chiang, A.S.4
  • 209
    • 0026719035 scopus 로고
    • Involvement of the N-methyl D-aspartate (NMDA) receptor in synapse elimination during cerebellar development
    • Rabacchi, S., Bailly, Y., Delhaye-Bouchaud, N. & Mariani, J. 1992 Involvement of the N-methyl D-aspartate (NMDA) receptor in synapse elimination during cerebellar development. Science 256, 1823-1825.
    • (1992) Science , vol.256 , pp. 1823-1825
    • Rabacchi, S.1    Bailly, Y.2    Delhaye-Bouchaud, N.3    Mariani, J.4
  • 210
    • 0038324076 scopus 로고    scopus 로고
    • Developmental and evolutionary adaptations of cortical radial glia
    • Rakic, P. 2003 Developmental and evolutionary adaptations of cortical radial glia. Cereb. Cortex 13, 541-549.
    • (2003) Cereb. Cortex , vol.13 , pp. 541-549
    • Rakic, P.1
  • 212
    • 0017308105 scopus 로고
    • D-Amino acids in higher plants
    • Robinson, T. 1976 D-Amino acids in higher plants. Life Sci. 19, 1097-1102.
    • (1976) Life Sci. , vol.19 , pp. 1097-1102
    • Robinson, T.1
  • 213
    • 0028872674 scopus 로고
    • Excitotoxicity and the NMDA receptor: Still lethal after eight years
    • Rothman, S. M. & Olney, J. W. 1995 Excitotoxicity and the NMDA receptor: still lethal after eight years. Trends Neurosci. 18, 57-58.
    • (1995) Trends Neurosci. , vol.18 , pp. 57-58
    • Rothman, S.M.1    Olney, J.W.2
  • 214
    • 0032555266 scopus 로고    scopus 로고
    • Geometric and viscous components of the tortuosity of the extracellular space in the brain
    • Rusakov, D. A. & Kullmann, D. M. 1998 Geometric and viscous components of the tortuosity of the extracellular space in the brain. Proc. Natl Acad. Sci. USA 95, 8975-8980.
    • (1998) Proc. Natl Acad. Sci. USA , vol.95 , pp. 8975-8980
    • Rusakov, D.A.1    Kullmann, D.M.2
  • 216
    • 0028281750 scopus 로고
    • Multiple evolutionary origin of pyridoxal-5′-phosphate-dependent amino acid decarboxylases
    • Sandmeier, E., Hale, T. I. & Christen, P. 1994 Multiple evolutionary origin of pyridoxal-5′-phosphate-dependent amino acid decarboxylases. Eur. J. Biochem. 221, 997-1002.
    • (1994) Eur. J. Biochem. , vol.221 , pp. 997-1002
    • Sandmeier, E.1    Hale, T.I.2    Christen, P.3
  • 217
    • 0038147361 scopus 로고    scopus 로고
    • Distribution and characteristics of D-amino acid and D-aspartate oxidases in fish tissues
    • Sarower, M. G., Matsui, T. & Abe, H. 2003 Distribution and characteristics of D-amino acid and D-aspartate oxidases in fish tissues. J. Exp. Zool. A 295, 151-159.
    • (2003) J. Exp. Zool. A , vol.295 , pp. 151-159
    • Sarower, M.G.1    Matsui, T.2    Abe, H.3
  • 220
    • 0028988978 scopus 로고
    • D-Serine, an endogenous synaptic modulator: Localization to astrocytes and glutamate-stimulated release
    • Schell, M. J., Molliver, M. E. & Snyder, S. H. 1995 D-Serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release. Proc. Natl Acad. Sci. USA 92, 3948-3952.
    • (1995) Proc. Natl Acad. Sci. USA , vol.92 , pp. 3948-3952
    • Schell, M.J.1    Molliver, M.E.2    Snyder, S.H.3
  • 221
    • 0031043465 scopus 로고    scopus 로고
    • D-Aspartate localizations imply neuronal and neuroendocrine roles
    • Schell, M. J., Cooper, O. B. & Snyder, S. H. 1997a D-Aspartate localizations imply neuronal and neuroendocrine roles. Proc. Natl Acad. Sci. USA 94, 2013-2018.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 2013-2018
    • Schell, M.J.1    Cooper, O.B.2    Snyder, S.H.3
  • 222
    • 0031046980 scopus 로고    scopus 로고
    • D-Serine as a neuromodulator: Regional and developmental localizations in rat brain glia resemble NMDA receptors
    • Schell, M. J., Brady Jr, R. O., Molliver, M. E. & Snyder, S. H. 1997b D-Serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors. J. Neurosci. 17, 1604-1615.
    • (1997) J. Neurosci. , vol.17 , pp. 1604-1615
    • Schell, M.J.1    Brady Jr., R.O.2    Molliver, M.E.3    Snyder, S.H.4
  • 224
    • 0021736481 scopus 로고
    • Molecular regulators of brain function: A new view
    • Schmitt, F. O. 1984 Molecular regulators of brain function: a new view. Neuroscience 13, 991-1001.
    • (1984) Neuroscience , vol.13 , pp. 991-1001
    • Schmitt, F.O.1
  • 225
    • 0027536702 scopus 로고
    • Neuronalastrocytic interactions in glutamate metabolism
    • Schousboe, A., Westergaard, N. & Hertz, L. 1993 Neuronalastrocytic interactions in glutamate metabolism. Biochem. Soc. Trans. 21, 49-53.
    • (1993) Biochem. Soc. Trans. , vol.21 , pp. 49-53
    • Schousboe, A.1    Westergaard, N.2    Hertz, L.3
  • 227
    • 0031713339 scopus 로고    scopus 로고
    • A genome-wide search for schizophrenia susceptibility genes
    • Shaw, S. H. (and 12 others) 1998 A genome-wide search for schizophrenia susceptibility genes. Am. J. Med. Genet. 81, 364-376.
    • (1998) Am. J. Med. Genet. , vol.81 , pp. 364-376
    • Shaw, S.H.1
  • 228
  • 230
    • 0014707413 scopus 로고
    • D-Cycloserine therapy of psychosis by symptom provocation
    • Simeon, J., Fink, M., Itil, T. M. & Ponce, D. 1970 D-Cycloserine therapy of psychosis by symptom provocation. Comp. Psychiatry 11, 80-88.
    • (1970) Comp. Psychiatry , vol.11 , pp. 80-88
    • Simeon, J.1    Fink, M.2    Itil, T.M.3    Ponce, D.4
  • 232
    • 0027049205 scopus 로고
    • Do astrocytes process neural information?
    • Smith, S. J. 1992 Do astrocytes process neural information? Prog. Brain Res. 94, 119-136.
    • (1992) Prog. Brain Res. , vol.94 , pp. 119-136
    • Smith, S.J.1
  • 233
    • 0344604592 scopus 로고
    • Biosynthesis of D-serine in the silkworm, Bombyx mori
    • Srinivasan, N. G. 1965 Biosynthesis of D-serine in the silkworm, Bombyx mori. J. Biol. Chem. 240, 796-800.
    • (1965) J. Biol. Chem. , vol.240 , pp. 796-800
    • Srinivasan, N.G.1
  • 234
    • 0030238292 scopus 로고    scopus 로고
    • D-Cycloserine causes transient enhancement of memory for a weak aversive stimulus in day-old chicks (Gallus domesticus)
    • Steele, R. J., Dermon, C. R. & Stewart, M. G. 1996 D-Cycloserine causes transient enhancement of memory for a weak aversive stimulus in day-old chicks (Gallus domesticus). Neurobiol. Learn. Mem. 66, 236-240.
    • (1996) Neurobiol. Learn. Mem. , vol.66 , pp. 236-240
    • Steele, R.J.1    Dermon, C.R.2    Stewart, M.G.3
  • 235
    • 0028559605 scopus 로고
    • Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins
    • Stern-Bach, Y., Bettler, B., Hartley, M., Sheppard, P. O., O'Hara, P. J. & Heinemann, S. F. 1994 Agonist selectivity of glutamate receptors is specified by two domains structurally related to bacterial amino acid-binding proteins. Neuron 13, 1345-1357.
    • (1994) Neuron , vol.13 , pp. 1345-1357
    • Stern-Bach, Y.1    Bettler, B.2    Hartley, M.3    Sheppard, P.O.4    O'Hara, P.J.5    Heinemann, S.F.6
  • 236
    • 0037636496 scopus 로고    scopus 로고
    • D-Serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors
    • Stevens, E. R., Esguerra, M., Kim, P. M., Newman, E. A., Snyder, S. H., Zahs, K. R. & Miller, R. F. 2003 D-Serine and serine racemase are present in the vertebrate retina and contribute to the physiological activation of NMDA receptors. Proc. Natl Acad. Sci. USA 100, 6789-6794.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 6789-6794
    • Stevens, E.R.1    Esguerra, M.2    Kim, P.M.3    Newman, E.A.4    Snyder, S.H.5    Zahs, K.R.6    Miller, R.F.7
  • 238
    • 0037704436 scopus 로고    scopus 로고
    • Multiple cell populations in the early postnatal subventricular zone take distinct migratory pathways: A dynamic study of glial and neuronal progenitor migration
    • Suzuki, S. O. & Goldman, J. E. 2003 Multiple cell populations in the early postnatal subventricular zone take distinct migratory pathways: a dynamic study of glial and neuronal progenitor migration. J. Neurosci. 23, 4240-4250.
    • (2003) J. Neurosci. , vol.23 , pp. 4240-4250
    • Suzuki, S.O.1    Goldman, J.E.2
  • 239
    • 0030813941 scopus 로고    scopus 로고
    • In vivo evidence for the link between L- and D-serine metabolism in rat cerebral cortex
    • Takahashi, K., Hayashi, F. & Nishikawa, T. 1997 In vivo evidence for the link between L- and D-serine metabolism in rat cerebral cortex. J. Neurochem. 69, 1286-1290.
    • (1997) J. Neurochem. , vol.69 , pp. 1286-1290
    • Takahashi, K.1    Hayashi, F.2    Nishikawa, T.3
  • 240
    • 0027256676 scopus 로고
    • Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria
    • Tam, R. & Saier Jr, M. H. 1993 Structural, functional, and evolutionary relationships among extracellular solute-binding receptors of bacteria. Microbiol. Rev. 57, 320-346.
    • (1993) Microbiol. Rev. , vol.57 , pp. 320-346
    • Tam, R.1    Saier Jr., M.H.2
  • 241
    • 0034616074 scopus 로고    scopus 로고
    • Immunohistochemical localization of N-methyl-D-aspartate receptor NR1, NR2A, NR2B and NR2C/D subunits in the adult mammalian cerebellum
    • Thompson, C. L., Drewery, D. L., Atkins, H. D., Stephenson, F. A. & Chazot, P. L. 2000 Immunohistochemical localization of N-methyl-D-aspartate receptor NR1, NR2A, NR2B and NR2C/D subunits in the adult mammalian cerebellum. Neurosci. Lett. 283, 85-88.
    • (2000) Neurosci. Lett. , vol.283 , pp. 85-88
    • Thompson, C.L.1    Drewery, D.L.2    Atkins, H.D.3    Stephenson, F.A.4    Chazot, P.L.5
  • 242
    • 0029927343 scopus 로고    scopus 로고
    • Metabolic coupling between glia and neurons
    • Tsacopoulos, M. & Magistretti, J. 1996 Metabolic coupling between glia and neurons. J. Neurosci. 16, 877-885.
    • (1996) J. Neurosci. , vol.16 , pp. 877-885
    • Tsacopoulos, M.1    Magistretti, J.2
  • 243
    • 0032403626 scopus 로고    scopus 로고
    • D-Serine added to antipsychotics for the treatment of schizophrenia
    • Tsai, G., Yang, P., Chung, L. C., Lange, N. & Coyle, J. T. 1998 D-Serine added to antipsychotics for the treatment of schizophrenia. Biol. Psychiatry 44, 1081-1089.
    • (1998) Biol. Psychiatry , vol.44 , pp. 1081-1089
    • Tsai, G.1    Yang, P.2    Chung, L.C.3    Lange, N.4    Coyle, J.T.5
  • 245
    • 0034944643 scopus 로고    scopus 로고
    • The putative glutamate receptors from plants are related to two superfamilies of animal neurotransmitter receptors via distinct evolutionary mechanisms
    • Turano, F. J., Panta, G. R., Allard, M. W. & Van Berkum, P. 2001 The putative glutamate receptors from plants are related to two superfamilies of animal neurotransmitter receptors via distinct evolutionary mechanisms. Mol. Biol. Evol. 18, 1417-1420.
    • (2001) Mol. Biol. Evol. , vol.18 , pp. 1417-1420
    • Turano, F.J.1    Panta, G.R.2    Allard, M.W.3    Van Berkum, P.4
  • 246
    • 0032496012 scopus 로고    scopus 로고
    • Occurrence of pyridoxal 5′-phosphate-dependent serine racemase in silkworm, Bombyx mori
    • Uo, T., Yoshimura, T., Shimizu, S. & Esaki, N. 1998 Occurrence of pyridoxal 5′-phosphate-dependent serine racemase in silkworm, Bombyx mori. Biochem. Biophys. Res. Commun. 246, 31-34.
    • (1998) Biochem. Biophys. Res. Commun. , vol.246 , pp. 31-34
    • Uo, T.1    Yoshimura, T.2    Shimizu, S.3    Esaki, N.4
  • 247
    • 0022975970 scopus 로고
    • Immunocytochemical localization of D-amino acid oxidase in the central clear matrix of rat kidney peroxisomes
    • Usuda, N., Yokota, S., Hashimoto, T. & Nagata, T. 1986 Immunocytochemical localization of D-amino acid oxidase in the central clear matrix of rat kidney peroxisomes. J. Histochem. Cytochem. 34, 1709-1718.
    • (1986) J. Histochem. Cytochem. , vol.34 , pp. 1709-1718
    • Usuda, N.1    Yokota, S.2    Hashimoto, T.3    Nagata, T.4
  • 249
    • 0025977764 scopus 로고
    • D-Aspartate oxidase, a peroxisomal enzyme in liver of rat and man
    • Van Veldhoven, P. P., Brees, C. & Mannaerts, P. 1991 D-Aspartate oxidase, a peroxisomal enzyme in liver of rat and man. Biochim. Biophys. Acta 1073, 203-208.
    • (1991) Biochim. Biophys. Acta , vol.1073 , pp. 203-208
    • Van Veldhoven, P.P.1    Brees, C.2    Mannaerts, P.3
  • 250
    • 0037172972 scopus 로고    scopus 로고
    • Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc 13-mediated vesicle priming
    • Varoqueaux, F., Sigler, A., Rhee, J. S., Brose, N., Enk, C., Reim, K. & Rosenmund, C. 2002 Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc 13-mediated vesicle priming. Proc. Natl Acad. Sci. USA 99, 9037-9042.
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 9037-9042
    • Varoqueaux, F.1    Sigler, A.2    Rhee, J.S.3    Brose, N.4    Enk, C.5    Reim, K.6    Rosenmund, C.7
  • 251
    • 0034603030 scopus 로고    scopus 로고
    • Synaptic assembly of the brain in the absence of neurotransmitter secretion
    • Verhage, M. (and 11 others) 2000 Synaptic assembly of the brain in the absence of neurotransmitter secretion. Science 287, 864-869.
    • (2000) Science , vol.287 , pp. 864-869
    • Verhage, M.1
  • 252
    • 0037291723 scopus 로고    scopus 로고
    • System L: Heteromeric exchangers of large, neutral amino acids involved in directional transport
    • Verrey, F. 2003 System L: heteromeric exchangers of large, neutral amino acids involved in directional transport. Pflügers Arch. 445, 529-533.
    • (2003) Pflügers Arch. , vol.445 , pp. 529-533
    • Verrey, F.1
  • 253
    • 0014823494 scopus 로고
    • Regional distribution of isozymes of D-amino-acid oxidase and acetylesterase in developing primate brain
    • Volpe, J. J., Lee, G., Laster, L. & Robinson, J. C. 1970 Regional distribution of isozymes of D-amino-acid oxidase and acetylesterase in developing primate brain. Exp. Neurol. 28, 76-87.
    • (1970) Exp. Neurol. , vol.28 , pp. 76-87
    • Volpe, J.J.1    Lee, G.2    Laster, L.3    Robinson, J.C.4
  • 254
    • 0028921951 scopus 로고
    • Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site
    • Wafford, K. A., Kathoria, M., Bain, C. J., Marshall, G., Le Bourdelles, B., Kemp, J. A. & Whiting, P. J. 1995 Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site. Mol. Pharmacol. 47, 374-380.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 374-380
    • Wafford, K.A.1    Kathoria, M.2    Bain, C.J.3    Marshall, G.4    Le Bourdelles, B.5    Kemp, J.A.6    Whiting, P.J.7
  • 255
    • 0028896984 scopus 로고
    • Glial uptake of intracerebroventricularly injected D-serine in the rat brain: An immunocytochemical study
    • Wako, K., Ma, N., Shiroyama, T. & Semba, R. 1995 Glial uptake of intracerebroventricularly injected D-serine in the rat brain: an immunocytochemical study. Neurosci. Lett. 185, 171-174.
    • (1995) Neurosci. Lett. , vol.185 , pp. 171-174
    • Wako, K.1    Ma, N.2    Shiroyama, T.3    Semba, R.4
  • 256
    • 0033593549 scopus 로고    scopus 로고
    • Divergence time estimates for the early history of animal phyla and the origin of plants, animals and fungi
    • DOI 10.1098/rspb.1999.0617
    • Wang, D. Y., Kumar, S. & Hedges, S. B. 1999 Divergence time estimates for the early history of animal phyla and the origin of plants, animals and fungi. Proc. R. Soc. Lond. B 266, 163-171. (DOI 10.1098/rspb.1999.0617.)
    • (1999) Proc. R. Soc. Lond. B , vol.266 , pp. 163-171
    • Wang, D.Y.1    Kumar, S.2    Hedges, S.B.3
  • 257
    • 85020829680 scopus 로고
    • PhD dissertation. The Johns Hopkins University, Baltimore, MD, USA
    • Weimar, R. W. 1977 D-Amino oxidase in mammalian cerebellum. PhD dissertation. The Johns Hopkins University, Baltimore, MD, USA.
    • (1977) D-Amino Oxidase in Mammalian Cerebellum
    • Weimar, R.W.1
  • 258
    • 0017663743 scopus 로고
    • The development of D-amino acid oxidase in rat cerebellum
    • Weimar, W. R. & Neims, A. H. 1977 The development of D-amino acid oxidase in rat cerebellum. J. Neurochem. 29, 649-656.
    • (1977) J. Neurochem. , vol.29 , pp. 649-656
    • Weimar, W.R.1    Neims, A.H.2
  • 259
    • 0028009515 scopus 로고
    • Concentrations of amino acids in extracellular fluid after opening of the blood-brain barrier by intracarotid infusion of protamine sulfate
    • Westergren, I., Nystrom, B., Hamberger, A., Nordborg, C. & Johansson, B. B. 1994 Concentrations of amino acids in extracellular fluid after opening of the blood-brain barrier by intracarotid infusion of protamine sulfate. J. Neurochem. 62, 159-165.
    • (1994) J. Neurochem. , vol.62 , pp. 159-165
    • Westergren, I.1    Nystrom, B.2    Hamberger, A.3    Nordborg, C.4    Johansson, B.B.5
  • 260
    • 0029973628 scopus 로고    scopus 로고
    • Glycine regulation of synaptic NMDA receptors in hippocampal neurons
    • Wilcox, K. S., Fitzsimonds, R. M., Johnson, B. & Dichter, M. A. 1996 Glycine regulation of synaptic NMDA receptors in hippocampal neurons. J. Neurophysiol. 76, 3415-3424.
    • (1996) J. Neurophysiol. , vol.76 , pp. 3415-3424
    • Wilcox, K.S.1    Fitzsimonds, R.M.2    Johnson, B.3    Dichter, M.A.4
  • 261
    • 0029921964 scopus 로고    scopus 로고
    • Activation of N-methyl-D-aspartate receptors by glycine: Role of an aspartate residue in the M3-M4 loop of the NR1 subunit
    • Williams, K., Chao, J., Kashiwagi, K., Masuko, T. & Igarashi, K. 1996 Activation of N-methyl-D-aspartate receptors by glycine: role of an aspartate residue in the M3-M4 loop of the NR1 subunit. Mol. Pharmacol. 50, 701-708.
    • (1996) Mol. Pharmacol. , vol.50 , pp. 701-708
    • Williams, K.1    Chao, J.2    Kashiwagi, K.3    Masuko, T.4    Igarashi, K.5
  • 262
    • 0033539510 scopus 로고    scopus 로고
    • Serine racemase: A glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission
    • Wolosker, H., Blackshaw, S. & Snyder, S. H. 1999a Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission. Proc. Natl Acad. Sci. USA 96, 13 409-13 414.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 13409-13414
    • Wolosker, H.1    Blackshaw, S.2    Snyder, S.H.3
  • 264
    • 0031023519 scopus 로고    scopus 로고
    • An alanine residue in the M3-M4 linker lines the glycine binding pocket of the N-methyl-D-aspartate receptor
    • Wood, M. W., VanDongen, H. M. & VanDongen, A. M. 1997 An alanine residue in the M3-M4 linker lines the glycine binding pocket of the N-methyl-D-aspartate receptor. J. Biol. Chem. 272, 3532-3537.
    • (1997) J. Biol. Chem. , vol.272 , pp. 3532-3537
    • Wood, M.W.1    VanDongen, H.M.2    VanDongen, A.M.3
  • 265
    • 0032742314 scopus 로고    scopus 로고
    • A mutation in the glycine binding pocket of the N-methyl-D-aspartate receptor NR1 subunit alters agonist efficacy
    • Wood, M. W., VanDongen, H. M. & VanDongen, A. M. 1999 A mutation in the glycine binding pocket of the N-methyl-D-aspartate receptor NR1 subunit alters agonist efficacy. Brain Res. Mol. Brain Res. 73, 189-192.
    • (1999) Brain Res. Mol. Brain Res. , vol.73 , pp. 189-192
    • Wood, M.W.1    VanDongen, H.M.2    VanDongen, A.M.3
  • 266
    • 0029077601 scopus 로고
    • The co-agonist concept: Is the NMDA-associated glycine receptor saturated in vivo?
    • Wood, P. L. 1995 The co-agonist concept: is the NMDA-associated glycine receptor saturated in vivo? Life Sci. 57, 301-310.
    • (1995) Life Sci. , vol.57 , pp. 301-310
    • Wood, P.L.1
  • 267
    • 0034811460 scopus 로고    scopus 로고
    • Uptake of D-serine by synaptosomal P2 fraction isolated from rat brain
    • Yamamoto, N., Tomita, U., Umino, A. & Nishikawa, T. 2001 Uptake of D-serine by synaptosomal P2 fraction isolated from rat brain. Synapse 42, 84-86.
    • (2001) Synapse , vol.42 , pp. 84-86
    • Yamamoto, N.1    Tomita, U.2    Umino, A.3    Nishikawa, T.4
  • 268
    • 0035895757 scopus 로고    scopus 로고
    • Immunohistochemical evidences for localization and production of D-serine in some neurons in the rat brain
    • Yasuda, E., Ma, N. & Semba, R. 2001 Immunohistochemical evidences for localization and production of D-serine in some neurons in the rat brain. Neurosci. Lett. 299, 162-164.
    • (2001) Neurosci. Lett. , vol.299 , pp. 162-164
    • Yasuda, E.1    Ma, N.2    Semba, R.3
  • 269
    • 0040209829 scopus 로고
    • Strychnine binding associated with glycine receptors of the central nervous system
    • Young, A. B. & Snyder, S. H. 1973 Strychnine binding associated with glycine receptors of the central nervous system. Proc. Natl Acad. Sci. USA 70, 2832-2836.
    • (1973) Proc. Natl Acad. Sci. USA , vol.70 , pp. 2832-2836
    • Young, A.B.1    Snyder, S.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.