Structural model of the N-methyl-D-aspartate receptor glycine site probed by site-directed chemical coupling

Journal of Biological Chemistry

Volumn 278, Issue 26, 2003, Pages 24011-24017

  Foucaud, Bernard ^a   Laube, Bodo ^b   Schemm, Rudolf ^b   Kreimeyer, Annett ^c   Goeldner, Maurice ^a   Betz, Heinrich ^b  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b MAX PLANCK INSTITUTE FOR BRAIN RESEARCH   (Germany)

^c EVOLOGIC SA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL BONDS; CHEMICAL SENSORS; CRYSTAL STRUCTURE; MOLECULAR STRUCTURE; MUTAGENESIS;

REACTIVE ANTAGONISTS;

AMINO ACIDS;

7 CHLORO 4 HYDROXY 3 (3 PHENOXYPHENYL) 2 QUINOLONE; AMPA RECEPTOR; GLUTAMIC ACID; GLYCINE; ION CHANNEL; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN GLUR2; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING SITE; CHANNEL GATING; COMPETITIVE INHIBITION; COVALENT BOND; CRYSTAL STRUCTURE; FEMALE; MOLECULAR MODEL; MUTAGENESIS; MUTANT; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN STRUCTURE; RECEPTOR BINDING; RECEPTOR INTRINSIC ACTIVITY; WILD TYPE; XENOPUS;

ANIMALS; BINDING SITES; ELECTROPHYSIOLOGY; EXCITATORY AMINO ACID ANTAGONISTS; GLYCINE; MICE; MODELS, MOLECULAR; MUTATION; OOCYTES; PROTEIN ENGINEERING; QUINOLONES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; XENOPUS;

ANIMALIA;

EID: 0038606161     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300219200     Document Type: Article

References (42)

1. Rogers, M., and Dani, J. A. (1995) Biophys. J. 68, 501-506
2. Dingledine, R., Borges, K., Bowie, D., and Traynelis, S. F. (1999) Pharmacol. Rev. 51, 7-61
3. Johnson, J. W., and Ascher, P. (1987) Nature 325, 529-531
4. Kleckner, N. W., and Dingledine, R. (1988) Science 241, 835-837
5. Laube, B., Kuhse, J., and Betz, H. (1998) J. Neurosci. 18, 2954-2961
6. Grimwood, S., Lebourdelles, B., and Whiting, P. J. (1995) J. Neurochem. 64, 525-530
7. Laube, B., Hirai, H., Sturgess, M., Betz, H., and Kuhse, J. (1997) Neuron 18, 493-503
8. Laurie, D. J., and Seeburg, P. H. (1994) Eur. J. Pharmacol. Mol. Pharm. 268, 335-345
9. Buller, A. L., Larson, H. C., Beaton, J. A., Morrisett, R. A., and Monaghan, D. T. (1994) J. Neurosci. 14, 5471-5484
10. Watanabe, M., Inoue, Y., Sakimura, K., and Mishina, M. (1992) Neuroreport 3, 1138-1140
11. Meldrum, B., and Garthwaite, J. (1990) Trends Pharmacol. Sci. 11, 379-387
12. Kornhuber, J., and Weller, M. (1997) Biol. Psychiatry 41, 135-144
13. Danysz, W., and Parsons, C. G. (1998) Pharmacol. Rev. 50, 597-664
14. Leeson, P. D., and Iversen, L. L. (1994) J. Med. Chem. 37, 4053-4067
15. Kuryatov, A., Laube, B., Betz, H., and Kuhse, J. (1994) Neuron 12, 1291-1300
16. Hirai, H., Kirsch, J., Laube, B., Betz, H., and Kuhse, J. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 6031-6036
17. Wafford, K. A., Kathoria, M., Bain, C. J., Marshall, G., Le Bourdellés, B., Kemp, J. A., and Whiting, P. (1995) Mol. Pharmacol. 47, 374-380
18. Williams, K., Chao, J., Kashiwagi, K., Masuko, T., and Igarashi, K. (1996) Mol. Pharmacol. 50, 701-708
19. Wood, M. W., VanDongen, H. M. A., and VanDongen, A. M. J. (1997) J. Biol. Chem. 272, 3532-3537
20. Uchino, S., Nakajima-Iijima, S., Okuda, K., Mishina, M., and Kawamoto, S. (1997) Neuroreport 8, 445-449
21. Ivanovic, A., Reilander, H., Laube, B., and Kuhse, J. (1998) J. Biol. Chem. 273, 19933-19937
22. Kulagowski, J. J., Baker, R., Curtis, N. R., Leeson, P. D., Mawer, I. M., Moseley, A. M., Ridgill, M. P., Rowley, M., Stansfield, I., and Foster, A. C. (1994) J. Med. Chem. 37, 1402-1405
23. Grimwood, S., Kulagowski, J. J., Mawer, L. M., Rowley, M., Leeson, P. D., and Foster, A. C. (1995) Eur. J. Pharmacol. Mol. Pharmacol. 290, 221-226
24. Perret, P., Sarda, X., Wolff, M., Bushey, D., and Goeldner, M. (1999) J. Biol. Chem. 274, 25350-25354
25. Foucaud, B., Perret, P., Grutter, T., and Goeldner, M. (2001) Trends Pharmacol. Sci. 22, 170-173
26. Karlin, A., and Akabas, M. H. (1998) Methods Enzymol. 293, 123-155
27. Kreimeyer, A., Laube, B., Sturgess, M., Goeldner, M., and Foucaud, B. (1999) J. Med. Chem. 42, 4394-4404
28. Armstrong, N., Sun, Y., Chen, G. Q., and Gouaux, E. (1998) Nature 395, 913-917
29. Wittekindt, B., Malany, S., Schemm, R., Otvos, L., Maccecchini, M. L., Laube, B., and Betz, H. (2001) Neuropharmacology 41, 753-761
30. Moriyoshi, K., Masu, M., Ishii, T., Shigemoto, R., Mizuno, N., and Nakanishi, S. (1991) Nature 354, 31-37
31. Oh, B. H., Pandit, J., Kang, C. H., Nikaido, K., Gokcen, S., Ames, G. F., and Kim, S. H. (1993) J. Biol. Chem. 268, 11348-11355
32. Leeson, P. D., Baker, R., Carling, R. W., Curtis, N. R., Moore, K. W., Williams, B. J., Foster, A. C., Donald, A. E., Kemp, J. A., and Marshall, G. R. (1991) J. Med. Chem. 34, 1343-1352
33. Cai, S. X., Zhou, Z. L., Huang, J. C., Whittemore, E. R., Egbuwoku, Z. O., Lu, Y. X., Hawkinson, J. E., Woodward, R. M., Weber, E., and Keana, J. F. W. (1996) J. Med. Chem. 39, 3248-3255
34. Auberson, Y. P., Acklin, P., Allgeier, H., Biollaz, M., Bischoff, S., Ofner, S., and Veenstra, S. J. (1998) Bioorg. Med. Chem. Lett. 8, 71-74
35. Jimonet, P., Audiau, F., Aloup, J. C., Barreau, M., Blanchard, J. C., Bohme, A., Boireau, A., Cheve, M., Damour, D., Doble, A., Lavayre, J., Dutrucrosset, G., Randle, J. C. R., Rataud, J., Stutzmann, J. M., and Mignani, S. (1994) Bioorg. Med. Chem. Lett. 4, 2735-2740
36. Cai, S. X., Kher, S. M., Zhou, Z. L., Ilyin, V., Espitia, S. A., Tran, M., Hawkinson, J. E., Woodward, R. M., Weber, E., and Keana, J. F. W. (1997) J. Med. Chem. 40, 730-738
37. Wood, M. W., VanDongen, H. M. A., and VanDongen, A. M. J. (1999) Mol. Brain Res. 73, 189-192
38. Colquhoun, D. (1998) Br. J. Pharmacol. 125, 924-947
39. Armstrong, N., and Gouaux, E. (2000) Neuron 28, 165-181
40. Chatterton, J. E., Awobuluyi, M., Premkumar, L. S., Takahashi, H., Talantova, M., Shin, Y., Cui, J., Tu, S., Sevarino, K. A., Nakanishi, N., Tong, G., Lipton, S. A., and Zhang, D. (2002) Nature 415, 793-798
41. Fern, R., Connolly, G. P., and Harrison, P. J. (1996) Neuroreport 7, 1953-1956
42. Louvel, E., Hugon, J., and Doble, A. (1997) Trends Pharmacol. Sci. 18, 196-203