Uptake of D-serine by synaptosomal P2 fraction isolated from rat brain

Synapse

Volumn 42, Issue 2, 2001, Pages 84-86

  Budygin, Evgeny A ^a   Phillips, Paul E M ^b   Mark Wightman, R ^a   Jones, Sara R ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

^b University of North Carolina at Chapel Hill   (United States)

Author keywords

3H D serine; Cerebellum; Cerebral cortex; Glycine; L serine; pH; Sodium ion

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; AMINO ACID; BETA ALANINE; DEXTRO GLUTAMIC ACID; DEXTRO SERINE; GLUTAMIC ACID; GLYCINE; SERINE; SODIUM;

AMINO ACID TRANSPORT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BRAIN CORTEX; BRAIN SYNAPTOSOME; CELL LEVEL; CEREBELLUM; CONTROLLED STUDY; MALE; MAMMAL; NONHUMAN; PH; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; TEMPERATURE DEPENDENCE;

ALANINE; ANIMALS; BINDING, COMPETITIVE; BRAIN; CARRIER PROTEINS; EXTRACELLULAR SPACE; GAMMA-AMINOBUTYRIC ACID; GLUTAMIC ACID; GLYCINE; ISOMERISM; MALE; NEURONS; NEUROTRANSMITTER AGENTS; PHARMACOKINETICS; RATS; RATS, WISTAR; SERINE; SYNAPTOSOMES; TEMPERATURE; TRITIUM;

EID: 0034811460     PISSN: 08874476     EISSN: None     Source Type: Journal    
DOI: 10.1002/syn.1103     Document Type: Article

References (15)

1. D-amino acids in animals
2. High-affinity transport of gamma-aminobutyric acid, glycine, taurine, L-aspartic acid, and L-glutamic acid in synaptosomal (P2) tissue: A kinetic and substrate specificity analysis
3. Identification and characterization of a Na(+)-independent neutral amino acid transporter that associates with the 4F2 heavy chain and exhibits substrate selectivity for small neutral D- and L-amino acids
4. The presence of free D-serine in rat brain
5. Endogenous D-serine in rat brain: N-methyl-D-aspartate receptor-related distribution and aging
6. Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis
7. Uptake of D- and L-serine in C6 glioma cells
8. Uptake of L-alanine, glycine and L-serine in the pigeon central nervous system
9. High affinity uptake systems for glycine, glutamic and aspartic acids in synaptosomes of rat central nervous tissues
10. 3H]D-serine binding to synaptosomal fraction isolated from rat brain tissues
11. 3H]kainic acid binding in the prefrontal cortex in schizophrenia
12. Modulation of a recombinant glycine transporter (GLYT1b) by activation of protein kinase C
13. D-serine, an endogenous synaptic modulator: Localization to astrocytes and glutamate-stimulated release
14. Glial uptake of intra-cerebroventricularly injected D-serine in the rat brain: An immuno cytochemical study