Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

Journal of Neuroscience

Volumn 20, Issue 11, 2000, Pages 4037-4049

  Kew, James N C ^a   Koester, Anja ^a,c   Moreau, Jean Luc ^a   Jenck, Francois ^a   Ouagazzal, Abdel Mouttalib ^a   Mutel, Vincent ^a   Richards, J Grayson ^a   Trube, Gerhard ^a   Fischer, Guenther ^a   Montkowski, Alexandra ^b   Hundt, Wolfgang ^b   Reinscheid, Rainer K ^b,d   Pauly Evers, Meike ^a   Kemp, John A ^a   Bluethmann, Horst ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b UNIVERSITY OF HAMBURG   (Germany)

^c ELI LILLY AND COMPANY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Glycine site; Grin1; LTP; NMDA receptor; NMDAR1; Spatial memory

Indexed keywords

GLYCINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL CELL; ARTICLE; AVERSIVE BEHAVIOR; CONTROLLED STUDY; EMBRYO; GENE ACTIVATION; GENE EXPRESSION; HIPPOCAMPUS; LEARNING; LONG TERM POTENTIATION; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; RECEPTOR AFFINITY; STARTLE REFLEX;

EID: 0034212705     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-11-04037.2000     Document Type: Article

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