-
1
-
-
16844381981
-
Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin
-
Adair BD, Xiong J-P, Maddock C, Goodman SL, Arnaout MA, Yeager M. 2005. Three-dimensional EM structure of the ectodomain of integrin αVβ3 in a complex with fibronectin. J. Cell Biol. 168:1109-18
-
(2005)
J. Cell Biol.
, vol.168
, pp. 1109-1118
-
-
Adair, B.D.1
Xiong, J.-P.2
Maddock, C.3
Goodman, S.L.4
Arnaout, M.A.5
Yeager, M.6
-
2
-
-
0037195164
-
Three-dimensional model of the human platelet integrin alpha IIb beta 3 based on electron cryomicroscopy and x-ray crystallography
-
Adair BD, Yeager M. 2002. Three-dimensional model of the human platelet integrin alpha IIb beta 3 based on electron cryomicroscopy and x-ray crystallography. Proc. Natl. Acad. Sci. USA 99:14059-64
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 14059-14064
-
-
Adair, B.D.1
Yeager, M.2
-
3
-
-
2942532190
-
Binding affinity of metal ions to the CDlIb A-domain is regulated by integrin activation and ligand
-
Ajroud K, Sugimori T, Goldmann WH, Fathallah DF, Xiong JP, Arnaout MA. 2004. Binding affinity of metal ions to the CDlIb A-domain is regulated by integrin activation and ligand J. Biol. Chem. 279:25483-88
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 25483-25488
-
-
Ajroud, K.1
Sugimori, T.2
Goldmann, W.H.3
Fathallah, D.F.4
Xiong, J.P.5
Arnaout, M.A.6
-
4
-
-
0029086272
-
Down regulation of talin alters cell adhesion and the processing of the alpha 5 beta 1 integrin
-
Albiges-Rizo C, Frachet P, Block MR. 1995. Down regulation of talin alters cell adhesion and the processing of the alpha 5 beta 1 integrin. J. Cell Sci. 108(Pt. 10):3317-29
-
(1995)
J. Cell Sci.
, vol.108
, Issue.PART 10
, pp. 3317-3329
-
-
Albiges-Rizo, C.1
Frachet, P.2
Block, M.R.3
-
5
-
-
0037076494
-
Does the integrin alpha a domain act as a ligand for its betaA domain?
-
Alonso JL, Essafi M, Xiong JP, Stehle T, Arnaout MA. 2002. Does the integrin alpha A domain act as a ligand for its betaA domain? Curr. Biol. 12:R340-42
-
(2002)
Curr. Biol.
, vol.12
-
-
Alonso, J.L.1
Essafi, M.2
Xiong, J.P.3
Stehle, T.4
Arnaout, M.A.5
-
6
-
-
0033601259
-
Determination of the border between the transmembrane and cytoplasmic domains of human integrin subunits
-
Armulik A, Nilsson I, von Heijne G, Johansson S. 1999. Determination of the border between the transmembrane and cytoplasmic domains of human integrin subunits. J. Biol. Chem. 274:37030-34
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37030-37034
-
-
Armulik, A.1
Nilsson, I.2
Von Heijne, G.3
Johansson, S.4
-
7
-
-
2942722352
-
Novel activating and inactivating mutations in the integrin beta 1 subunit a domain
-
Barton SJ, Travis MA, Askari JA, Buckley PA, Craig SE, et al. 2004. Novel activating and inactivating mutations in the integrin beta 1 subunit A domain. Biochem. J. 380:401-7
-
(2004)
Biochem. J.
, vol.380
, pp. 401-407
-
-
Barton, S.J.1
Travis, M.A.2
Askari, J.A.3
Buckley, P.A.4
Craig, S.E.5
-
8
-
-
20244366055
-
The state diagram for cell adhesion mediated by two receptors
-
Bhatia SK, King MR, Hammer DA. 2003. The state diagram for cell adhesion mediated by two receptors. Biophys. J. 84:2671-90
-
(2003)
Biophys. J.
, vol.84
, pp. 2671-2690
-
-
Bhatia, S.K.1
King, M.R.2
Hammer, D.A.3
-
9
-
-
0036220127
-
Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation
-
Beglova N, Blacklow SC, Takagi J, Springer TA. 2002. Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation. Nat. Struct. Biol. 9:282-87
-
(2002)
Nat. Struct. Biol.
, vol.9
, pp. 282-287
-
-
Beglova, N.1
Blacklow, S.C.2
Takagi, J.3
Springer, T.A.4
-
10
-
-
0036774751
-
Talin is essential for integrin function in Drosophila
-
Brown NH, Gregory SL, Rickoll WL, Fessier LI, Prout M, et al. 2002. Talin is essential for integrin function in Drosophila. Dev. Cell 3:569-79
-
(2002)
Dev. Cell
, vol.3
, pp. 569-579
-
-
Brown, N.H.1
Gregory, S.L.2
Rickoll, W.L.3
Fessier, L.I.4
Prout, M.5
-
11
-
-
0035202874
-
Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration
-
Calderwood DA, Huttenlocher A, Kiosses WB, Rose DM, Woodside DG, et al. 2001. Increased filamin binding to beta-integrin cytoplasmic domains inhibits cell migration. Nat. Cell 3:1060-68
-
(2001)
Nat. Cell
, vol.3
, pp. 1060-1068
-
-
Calderwood, D.A.1
Huttenlocher, A.2
Kiosses, W.B.3
Rose, D.M.4
Woodside, D.G.5
-
12
-
-
0037131270
-
Agonist-specific structural rearrangements of integrin alpha IIb beta 3. Confirmation of the bent conformation in platelets at rest and after activation
-
Calzada MJ, Alvarez MV, Gonzalez-Rodriguez J. 2002. Agonist-specific structural rearrangements of integrin alpha IIb beta 3. Confirmation of the bent conformation in platelets at rest and after activation. J. Biol. Chem. 277:39899-908
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39899-39908
-
-
Calzada, M.J.1
Alvarez, M.V.2
Gonzalez-Rodriguez, J.3
-
13
-
-
0000449348
-
Ribbon models of macromolecules
-
Carson M. 1987. Ribbon models of macromolecules. J. Mol. Graph. 5:103-6
-
(1987)
J. Mol. Graph.
, vol.5
, pp. 103-106
-
-
Carson, M.1
-
14
-
-
0344628802
-
Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster
-
Chen J, Salas A, Springer TA. 2003. Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster. Nat. Struct. Biol. 10:995-1001
-
(2003)
Nat. Struct. Biol.
, vol.10
, pp. 995-1001
-
-
Chen, J.1
Salas, A.2
Springer, T.A.3
-
15
-
-
0035966054
-
Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation
-
Chigaev A, Blenc AM, Braaten JV, Kumaraswamy N, Kepley CL, et al. 2001. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. J. Biol. Chem. 276:48670-78
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 48670-48678
-
-
Chigaev, A.1
Blenc, A.M.2
Braaten, J.V.3
Kumaraswamy, N.4
Kepley, C.L.5
-
16
-
-
0344981532
-
FRET detection of cellular alpha 4-integrin conformational activation
-
Chigaev A, Buranda T, Dwyer DC, Prossnitz ER, Sklar LA. 2003. FRET detection of cellular alpha 4-integrin conformational activation. Biophys. J. 85:3951-62
-
(2003)
Biophys. J.
, vol.85
, pp. 3951-3962
-
-
Chigaev, A.1
Buranda, T.2
Dwyer, D.C.3
Prossnitz, E.R.4
Sklar, L.A.5
-
17
-
-
0020619733
-
A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa
-
Coller BS, Peerschke EI, Scudder LE, Sullivan CA. 1983. A murine monoclonal antibody that completely blocks the binding of fibrinogen to platelets produces a thrombasthenic-like state in normal platelets and binds to glycoproteins IIb and/or IIIa. J. Clin. Invest. 72:325-38
-
(1983)
J. Clin. Invest.
, vol.72
, pp. 325-338
-
-
Coller, B.S.1
Peerschke, E.I.2
Scudder, L.E.3
Sullivan, C.A.4
-
18
-
-
0034507687
-
Chemokines trigger immediate beta2 integrin affinity and mobility changes: Differential regulation and roles in lymphocyte arrest under flow
-
Constantin G, Majeed M, Giagulli C, Piccio L, Kim JY, et al. 2000. Chemokines trigger immediate beta2 integrin affinity and mobility changes: differential regulation and roles in lymphocyte arrest under flow. Immunity 13:759-69
-
(2000)
Immunity
, vol.13
, pp. 759-769
-
-
Constantin, G.1
Majeed, M.2
Giagulli, C.3
Piccio, L.4
Kim, J.Y.5
-
19
-
-
0037379072
-
How do helix-helix interactions help determine the folds of membrane proteins? Perspectives from the study of homo-oligomeric helical bundles
-
DeGrado WF, Gratkowski H, Lear JD. 2003. How do helix-helix interactions help determine the folds of membrane proteins? Perspectives from the study of homo-oligomeric helical bundles. Protein Sci. 12:647-65
-
(2003)
Protein Sci.
, vol.12
, pp. 647-665
-
-
Degrado, W.F.1
Gratkowski, H.2
Lear, J.D.3
-
20
-
-
0026601096
-
Divalent cation regulation of the function of the leukocyte integrin LFA-1
-
Dransfield I, Cabanas C, Craig A, Hogg N. 1992. Divalent cation regulation of the function of the leukocyte integrin LFA-1. J. Cell Biol. 116:219-26
-
(1992)
J. Cell Biol.
, vol.116
, pp. 219-226
-
-
Dransfield, I.1
Cabanas, C.2
Craig, A.3
Hogg, N.4
-
21
-
-
14844323998
-
Dual function for a unique site within the {beta2}I domain of integrin {alpha}M{beta}2
-
Ehirchiou D, Xiong YM, Li Y, Brew S, Zhang L. 2005. Dual function for a unique site within the {beta2}I domain of integrin {alpha}M{beta}2. J. Biol. Chem. 280:8324-31
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 8324-8331
-
-
Ehirchiou, D.1
Xiong, Y.M.2
Li, Y.3
Brew, S.4
Zhang, L.5
-
22
-
-
0034737296
-
Structural basis of collagen recognition by integrin alpha2beta1
-
Emsley J, Knight CG, Farndale RW, Barnes MJ, Liddington RC. 2000. Structural basis of collagen recognition by integrin alpha2beta1. Cell 101:47-56
-
(2000)
Cell
, vol.101
, pp. 47-56
-
-
Emsley, J.1
Knight, C.G.2
Farndale, R.W.3
Barnes, M.J.4
Liddington, R.C.5
-
23
-
-
0028773130
-
Structure of a soluble, glycosylated form of the human complement regulatory protein CD59
-
Fletcher CM, Harrison RA, Lachmann PJ, Neuhaus D. 1994. Structure of a soluble, glycosylated form of the human complement regulatory protein CD59. Structure 2:185-99
-
(1994)
Structure
, vol.2
, pp. 185-199
-
-
Fletcher, C.M.1
Harrison, R.A.2
Lachmann, P.J.3
Neuhaus, D.4
-
24
-
-
0037053341
-
Role of integrin-linked kinase in leukocyte recruitment
-
Friedrich EB, Sinha S, Li L, Dedhar S, Force T, et al. 2002. Role of integrin-linked kinase in leukocyte recruitment. J. Biol. Chem. 277:16371-75
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 16371-16375
-
-
Friedrich, E.B.1
Sinha, S.2
Li, L.3
Dedhar, S.4
Force, T.5
-
25
-
-
18244370299
-
Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule
-
Gadek TR, Burdick DJ, McDowell RS, Stanley MS, Marsters JC Jr, et al. 2002. Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule. Science 295:1086-89
-
(2002)
Science
, vol.295
, pp. 1086-1089
-
-
Gadek, T.R.1
Burdick, D.J.2
McDowell, R.S.3
Stanley, M.S.4
Marsters Jr., J.C.5
-
26
-
-
0037238844
-
Structural determinants of integrin recognition by talin
-
Garcia-Alvarez B, de Pereda JM, Calderwood DA, Ulmer TS, Critchley D, et al. 2003. Structural determinants of integrin recognition by talin. Mol. Cell 11:49-58
-
(2003)
Mol. Cell
, vol.11
, pp. 49-58
-
-
Garcia-Alvarez, B.1
De Pereda, J.M.2
Calderwood, D.A.3
Ulmer, T.S.4
Critchley, D.5
-
27
-
-
1642578985
-
RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: Critical role of LFA-1 affinity triggering in lymphocyte in vivo homing
-
Giagulli C, Scarpini E, Ottoboni L, Narumiya S, Butcher EC, et al. 2004. RhoA and zeta PKC control distinct modalities of LFA-1 activation by chemokines: critical role of LFA-1 affinity triggering in lymphocyte in vivo homing. Immunity 20:25-35
-
(2004)
Immunity
, vol.20
, pp. 25-35
-
-
Giagulli, C.1
Scarpini, E.2
Ottoboni, L.3
Narumiya, S.4
Butcher, E.C.5
-
29
-
-
0035094475
-
Geometry of metal-ligand interactions in proteins
-
Harding MM. 2001. Geometry of metal-ligand interactions in proteins. Acta Crystallogr. D 57:401-11
-
(2001)
Acta Crystallogr. D
, vol.57
, pp. 401-411
-
-
Harding, M.M.1
-
30
-
-
0032578007
-
Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alpha IIb beta 3
-
Hato T, Pampori N, Shattil SJ. 1998. Complementary roles for receptor clustering and conformational change in the adhesive and signaling functions of integrin alpha IIb beta 3. J. Cell Biol. 141:1685-95
-
(1998)
J. Cell Biol.
, vol.141
, pp. 1685-1695
-
-
Hato, T.1
Pampori, N.2
Shattil, S.J.3
-
31
-
-
0344708475
-
Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain
-
Hemler ME. 2003. Tetraspanin proteins mediate cellular penetration, invasion, and fusion events and define a novel type of membrane microdomain. Annu. Rev. Cell Dev. Biol. 19:397-422
-
(2003)
Annu. Rev. Cell Dev. Biol.
, vol.19
, pp. 397-422
-
-
Hemler, M.E.1
-
32
-
-
1542618323
-
Attractant binding alters arrangement of chemoreceptor dimers within its cluster at a cell pole
-
Homma M, Shiomi D, Kawagishi I. 2004. Attractant binding alters arrangement of chemoreceptor dimers within its cluster at a cell pole. Proc. Natl. Acad. Sci. USA 101:3462-67
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 3462-3467
-
-
Homma, M.1
Shiomi, D.2
Kawagishi, I.3
-
33
-
-
0033582510
-
A new model of dual interacting ligand binding sites on integrin alpha IIb beta 3
-
Hu DD, White CA, Panzer-Knodle S, Page JD, Nicholson N, Smith JW. 1999. A new model of dual interacting ligand binding sites on integrin alpha IIb beta 3. J. Biol. Chem. 274:4633-39
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 4633-4639
-
-
Hu, D.D.1
White, C.A.2
Panzer-Knodle, S.3
Page, J.D.4
Nicholson, N.5
Smith, J.W.6
-
34
-
-
0029966310
-
Breaking the integrin hinge
-
Hughes PE, Diaz-Gonzalez F, Leong L, Wu C, McDonald JA, et al. 1996. Breaking the integrin hinge. J. Biol. Chem. 271:6571-74
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 6571-6574
-
-
Hughes, P.E.1
Diaz-Gonzalez, F.2
Leong, L.3
Wu, C.4
McDonald, J.A.5
-
35
-
-
0030909050
-
Suppression of integrin activation: A novel function of a Ras/Raf-initiated MAP kinase pathway
-
Hughes PE, RenshawMW, Pfaff M, Forsyth J, Keivens KM, et al. 1997. Suppression of integrin activation: A novel function of a Ras/Raf-initiated MAP kinase pathway. Cell 88:521-30
-
(1997)
Cell
, vol.88
, pp. 521-530
-
-
Hughes, P.E.1
Renshaw, M.W.2
Pfaff, M.3
Forsyth, J.4
Keivens, K.M.5
-
37
-
-
0037452771
-
Mechanosensation through integrins: Cells act locally but think globally
-
Ingber DE. 2003. Mechanosensation through integrins: cells act locally but think globally. Proc. Natl. Acad. Sci. USA 100:1472-74
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1472-1474
-
-
Ingber, D.E.1
-
38
-
-
3342958175
-
Identification of integrin beta subunit mutations that alter heterodimer function in situ
-
Jannuzi AL, Bunch TA, West RF, Brower DL. 2004. Identification of integrin beta subunit mutations that alter heterodimer function in situ. Mol. Biol. Cell 15:3829-40
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3829-3840
-
-
Jannuzi, A.L.1
Bunch, T.A.2
West, R.F.3
Brower, D.L.4
-
39
-
-
0041461882
-
Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin
-
Jiang G, Giannone G, Critchley DR, Fukumoto E, Sheetz MP. 2003. Two-piconewton slip bond between fibronectin and the cytoskeleton depends on talin. Nature 424:334-37
-
(2003)
Nature
, vol.424
, pp. 334-337
-
-
Jiang, G.1
Giannone, G.2
Critchley, D.R.3
Fukumoto, E.4
Sheetz, M.P.5
-
40
-
-
0033543673
-
Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain
-
Kallen J, Welzenbach K, Ramage P, Geyl D, Kriwacki R, et al. 1999. Structural basis for LFA-1 inhibition upon lovastatin binding to the CD11a I-domain. J. Mol. Biol. 292:1-9
-
(1999)
J. Mol. Biol.
, vol.292
, pp. 1-9
-
-
Kallen, J.1
Welzenbach, K.2
Ramage, P.3
Geyl, D.4
Kriwacki, R.5
-
41
-
-
1642504824
-
Critical cysteine residues for regulation of integrin alpha IIb beta 3 are clustered in the epidermal growth factor domains of the beta 3 subunit
-
Kamata T, Ambo H, Puzon-McLaughlin W, Tieu KK, Handa M, et al. 2004. Critical cysteine residues for regulation of integrin alpha IIb beta 3 are clustered in the epidermal growth factor domains of the beta 3 subunit. Biochem. J. 378:1079-82
-
(2004)
Biochem. J.
, vol.378
, pp. 1079-1082
-
-
Kamata, T.1
Ambo, H.2
Puzon-McLaughlin, W.3
Tieu, K.K.4
Handa, M.5
-
42
-
-
0037432552
-
Crystal structure of the alpha 1 beta 1 integrin I domain in complex with an antibody Fab fragment
-
Karpusas M, Ferrant J, Weinreb PH, Carmillo A, Taylor FR, Garber EA. 2003. Crystal structure of the alpha 1 beta 1 integrin I domain in complex with an antibody Fab fragment. J. Mol. Biol. 327:1031-41
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 1031-1041
-
-
Karpusas, M.1
Ferrant, J.2
Weinreb, P.H.3
Carmillo, A.4
Taylor, F.R.5
Garber, E.A.6
-
43
-
-
0042681786
-
Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins
-
Kim M, Carman CV, Springer TA. 2003a. Bidirectional transmembrane signaling by cytoplasmic domain separation in integrins. Science 301:1720-25
-
(2003)
Science
, vol.301
, pp. 1720-1725
-
-
Kim, M.1
Carman, C.V.2
Springer, T.A.3
-
44
-
-
11244274075
-
The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2
-
Kim M, Carman CV, Yang W, Salas A, Springer TA. 2004. The primacy of affinity over clustering in regulation of adhesiveness of the integrin {alpha}L{beta}2. J. Cell Biol. 167:1241-53
-
(2004)
J. Cell Biol.
, vol.167
, pp. 1241-1253
-
-
Kim, M.1
Carman, C.V.2
Yang, W.3
Salas, A.4
Springer, T.A.5
-
45
-
-
0038730774
-
A simple method for modeling transmembrane helix oligomers
-
Kim S, Chamberlain AK, Bowie JU. 2003b. A simple method for modeling transmembrane helix oligomers. J. Mol. Biol. 329:831-40
-
(2003)
J. Mol. Biol.
, vol.329
, pp. 831-840
-
-
Kim, S.1
Chamberlain, A.K.2
Bowie, J.U.3
-
46
-
-
1642581670
-
LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rapl activation and impaired stabilization of integrin bonds
-
Kinashi T, Aker M, Sokolovsky-Eisenberg M, Grabovsky V, Tanaka C, et al. 2004. LAD-III, a leukocyte adhesion deficiency syndrome associated with defective Rapl activation and impaired stabilization of integrin bonds. Blood 103:1033-36
-
(2004)
Blood
, vol.103
, pp. 1033-1036
-
-
Kinashi, T.1
Aker, M.2
Sokolovsky-Eisenberg, M.3
Grabovsky, V.4
Tanaka, C.5
-
47
-
-
0141925955
-
Ras GTPases: Integrins' friends or foes?
-
Kinbara K, Goldfinger LE, Hansen M, Chou FL, Ginsberg MH. 2003. Ras GTPases: integrins' friends or foes? Nat. Rev. Mol. Cell Biol. 4:767-76
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 767-776
-
-
Kinbara, K.1
Goldfinger, L.E.2
Hansen, M.3
Chou, F.L.4
Ginsberg, M.H.5
-
48
-
-
0030050396
-
2.0 a crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region
-
Leahy DJ, Aukhil I, Erickson HP. 1996. 2.0 A crystal structure of a four-domain segment of human fibronectin encompassing the RGD loop and synergy region. Cell 84:155-64
-
(1996)
Cell
, vol.84
, pp. 155-164
-
-
Leahy, D.J.1
Aukhil, I.2
Erickson, H.P.3
-
49
-
-
0029646107
-
Two conformations of the integrin A-domain (I-domain): A pathway for activation?
-
Lee J-O, Bankston LA, Arnaout MA, Liddington RC. 1995a. Two conformations of the integrin A-domain (I-domain): a pathway for activation? Structure 3:1333-40
-
(1995)
Structure
, vol.3
, pp. 1333-1340
-
-
Lee, J.-O.1
Bankston, L.A.2
Arnaout, M.A.3
Liddington, R.C.4
-
50
-
-
0028986196
-
Crystal structure of the A-domain from the α-subunit of β2 integrin complement receptor type 3 (CR3, CD11b/CD18)
-
Lee J-O, Rieu P, Arnaout MA, Liddington R. 1995b. Crystal structure of the A-domain from the α-subunit of β2 integrin complement receptor type 3 (CR3, CD11b/CD18). Cell 80:631-38
-
(1995)
Cell
, vol.80
, pp. 631-638
-
-
Lee, J.-O.1
Rieu, P.2
Arnaout, M.A.3
Liddington, R.4
-
51
-
-
0035940359
-
Oligomerization of the integrin alpha IIb beta 3 : Roles of the transmembrane and cytoplasmic domains
-
Li R, Babu CR, Lear JD, Wand AJ, Bennett JS, DeGrado WF. 2001. Oligomerization of the integrin alpha IIb beta 3 : roles of the transmembrane and cytoplasmic domains. Proc. Natl. Acad. Sci. USA 98:12462-67
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 12462-12467
-
-
Li, R.1
Babu, C.R.2
Lear, J.D.3
Wand, A.J.4
Bennett, J.S.5
Degrado, W.F.6
-
52
-
-
0037207135
-
Characterization of the monomeric form of the transmembrane and cytoplasmic domains of the integrin beta 3 subunit by NMR spectroscopy
-
Li R, Babu CR, Valentine K, Lear JD, Wand AJ, et al. 2002a. Characterization of the monomeric form of the transmembrane and cytoplasmic domains of the integrin beta 3 subunit by NMR spectroscopy. Biochemistry 41:15618-24
-
(2002)
Biochemistry
, vol.41
, pp. 15618-15624
-
-
Li, R.1
Babu, C.R.2
Valentine, K.3
Lear, J.D.4
Wand, A.J.5
-
53
-
-
0036467479
-
Characterization of a conformationally sensitive murine monoclonal antibody directed to the metal ion-dependent adhesion site face of integrin CD11b
-
Li R, Haruta I, Rieu P, Sugimori T, Xiong JP, Arnaout MA. 2002b. Characterization of a conformationally sensitive murine monoclonal antibody directed to the metal ion-dependent adhesion site face of integrin CD11b. J. Immunol. 168:1219-25
-
(2002)
J. Immunol.
, vol.168
, pp. 1219-1225
-
-
Li, R.1
Haruta, I.2
Rieu, P.3
Sugimori, T.4
Xiong, J.P.5
Arnaout, M.A.6
-
54
-
-
0038644597
-
Activation of integrin alpha IIb beta 3 by modulation of transmembrane helix associations
-
Li R, Mitra N, Gratkowski H, Vilaire G, Litvinov R, et al. 2003. Activation of integrin alpha IIb beta 3 by modulation of transmembrane helix associations. Science 300:795-98
-
(2003)
Science
, vol.300
, pp. 795-798
-
-
Li, R.1
Mitra, N.2
Gratkowski, H.3
Vilaire, G.4
Litvinov, R.5
-
55
-
-
0032517824
-
Two functional states of the CD11b A-domain: Correlations with key features of two Mn2+-complexed crystal structures
-
Li R, Rieu P, Griffith DL, Scott D, Arnaout MA. 1998. Two functional states of the CD11b A-domain: correlations with key features of two Mn2+-complexed crystal structures. J. Cell Biol. 143:1523-34
-
(1998)
J. Cell Biol.
, vol.143
, pp. 1523-1534
-
-
Li, R.1
Rieu, P.2
Griffith, D.L.3
Scott, D.4
Arnaout, M.A.5
-
56
-
-
13444291852
-
A push-pull mechanism for regulating integrin function
-
Li W, Metcalf DG, Gorelik R, Li R, Mitra N, et al. 2005. A push-pull mechanism for regulating integrin function. Proc. Natl. Acad. Sci. USA 102:1424-29
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 1424-1429
-
-
Li, W.1
Metcalf, D.G.2
Gorelik, R.3
Li, R.4
Mitra, N.5
-
57
-
-
0037188509
-
Binding strength and activation state of single fibrinogen-integrin pairs on living cells
-
Litvinov RI, Shuman H, Bennett JS, Weisel JW. 2002. Binding strength and activation state of single fibrinogen-integrin pairs on living cells. Proc. Natl. Acad. Sci. USA 99:7426-31
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7426-7431
-
-
Litvinov, R.I.1
Shuman, H.2
Bennett, J.S.3
Weisel, J.W.4
-
58
-
-
0027364840
-
Direct evidence for two affinity states for lymphocyte function-associated antigen 1 on activated T cells
-
Lollo BA, Chan KWH, Hanson EM, Moy VT, Brian AA. 1993. Direct evidence for two affinity states for lymphocyte function-associated antigen 1 on activated T cells. J. Biol. Chem. 268:21693-700
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 21693-21700
-
-
Lollo, B.A.1
Chan, K.W.H.2
Hanson, E.M.3
Moy, V.T.4
Brian, A.A.5
-
59
-
-
0034479757
-
TOP: A new method for protein structure comparisons and similarity searches
-
Lu G. 2000. TOP: A new method for protein structure comparisons and similarity searches. J. Appl. Cryst. 33:176-83
-
(2000)
J. Appl. Cryst.
, vol.33
, pp. 176-183
-
-
Lu, G.1
-
60
-
-
0035422428
-
Cellular activation of leukocyte function-associated antigen-1 and its affinity are regulated at the I domain allosteric site
-
Lupher ML Jr, Harris EA, Beals CR, Sui LM, Liddington RC, Staunton DE. 2001. Cellular activation of leukocyte function-associated antigen-1 and its affinity are regulated at the I domain allosteric site. J. Immunol. 167:1431-39
-
(2001)
J. Immunol.
, vol.167
, pp. 1431-1439
-
-
Lupher Jr., M.L.1
Harris, E.A.2
Beals, C.R.3
Sui, L.M.4
Liddington, R.C.5
Staunton, D.E.6
-
61
-
-
0037418254
-
Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand
-
Luo BH, Springer TA, Takagi J. 2003 a. Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand. Proc. Natl. Acad. Sci. USA 100:2403-8
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2403-2408
-
-
Luo, B.H.1
Springer, T.A.2
Takagi, J.3
-
62
-
-
16644396938
-
A specific interface between integrin transmembrane helices and affinity for ligand
-
Luo BH, Springer TA, Takagi J. 2004a. A specific interface between integrin transmembrane helices and affinity for ligand. PLoS Biol. 2:e153
-
(2004)
PLoS Biol.
, vol.2
-
-
Luo, B.H.1
Springer, T.A.2
Takagi, J.3
-
63
-
-
3042602113
-
Allosteric beta 1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain
-
Luo BH, Strokovich K, Walz T, Springer TA, Takagi J. 2004b. Allosteric beta 1 integrin antibodies that stabilize the low affinity state by preventing the swing-out of the hybrid domain. J. Biol. Chem. 279:27466-71
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 27466-27471
-
-
Luo, B.H.1
Strokovich, K.2
Walz, T.3
Springer, T.A.4
Takagi, J.5
-
64
-
-
1642305349
-
Locking the beta 3 integrin I-like domain into high and low affinity conformations with disulfides
-
Luo BH, Takagi J, Springer TA. 2003b. Locking the beta 3 integrin I-like domain into high and low affinity conformations with disulfides. J. Biol. Chem. 279:10215-21
-
(2003)
J. Biol. Chem.
, vol.279
, pp. 10215-10221
-
-
Luo, B.H.1
Takagi, J.2
Springer, T.A.3
-
65
-
-
4944222601
-
P-selectin binding to P-selectin glycoprotein ligand-1 induces an intermediate state of alphaMbeta2 activation and acts cooperatively with extracellular stimuli to support maximal adhesion of human neutrophils
-
Ma YQ, Plow EF, Geng JG. 2004. P-selectin binding to P-selectin glycoprotein ligand-1 induces an intermediate state of alphaMbeta2 activation and acts cooperatively with extracellular stimuli to support maximal adhesion of human neutrophils. Blood 104:2549-56
-
(2004)
Blood
, vol.104
, pp. 2549-2556
-
-
Ma, Y.Q.1
Plow, E.F.2
Geng, J.G.3
-
66
-
-
0035877656
-
Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides
-
Martel V, Racaud-Sultan C, Dupe S, Marie C, Paulhe F, et al. 2001. Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides. J. Biol. Chem. 276:21217-27
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21217-21227
-
-
Martel, V.1
Racaud-Sultan, C.2
Dupe, S.3
Marie, C.4
Paulhe, F.5
-
67
-
-
0034121267
-
Talin controls the exit of the integrin alpha 5 beta 1 from an early compartment of the secretory pathway
-
Martel V, Vignoud L, Dupe S, Frachet P, Block MR, Albiges-Rizo C. 2000. Talin controls the exit of the integrin alpha 5 beta 1 from an early compartment of the secretory pathway. J. Cell Sci. 113(Pt. 11):1951-61
-
(2000)
J. Cell Sci.
, vol.113
, Issue.PART 11
, pp. 1951-1961
-
-
Martel, V.1
Vignoud, L.2
Dupe, S.3
Frachet, P.4
Block, M.R.5
Albiges-Rizo, C.6
-
68
-
-
0037616465
-
Engineered allosteric mutants of the integrin alphaM-beta2 I domain: Structural and functional studies
-
McCleverty CJ, Liddington RC. 2003. Engineered allosteric mutants of the integrin alphaM-beta2 I domain: structural and functional studies. Biochem. J. 372:121-27
-
(2003)
Biochem. J.
, vol.372
, pp. 121-127
-
-
McCleverty, C.J.1
Liddington, R.C.2
-
69
-
-
0027483226
-
A novel divalent cation-binding site in the a domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding
-
Michishita M, Videm V, Arnaout MA. 1993. A novel divalent cation-binding site in the A domain of the beta 2 integrin CR3 (CD11b/CD18) is essential for ligand binding. Cell 72:857-67
-
(1993)
Cell
, vol.72
, pp. 857-867
-
-
Michishita, M.1
Videm, V.2
Arnaout, M.A.3
-
70
-
-
0347695986
-
Role of ADMIDAS cation-binding site in ligand recognition by integrin {alpha}5{beta}1
-
Mould AP, Barton SJ, Askari JA, Craig SE, Humphries MJ. 2003a. Role of ADMIDAS cation-binding site in ligand recognition by integrin {alpha}5{beta}1. J. Biol. Chem. 278:51622-29
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51622-51629
-
-
Mould, A.P.1
Barton, S.J.2
Askari, J.A.3
Craig, S.E.4
Humphries, M.J.5
-
71
-
-
0013307787
-
Conformational changes in the integrin beta a domain provide a mechanism for signal transduction via hybrid domain movement
-
Mould AP, Barton SJ, Askari JA, McEwan PA, Buckley PA, et al. 2003b. Conformational changes in the integrin beta A domain provide a mechanism for signal transduction via hybrid domain movement. J. Biol. Chem. 278:17028-35
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17028-17035
-
-
Mould, A.P.1
Barton, S.J.2
Askari, J.A.3
McEwan, P.A.4
Buckley, P.A.5
-
72
-
-
0141960077
-
Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis
-
Mould AP, Symonds EJ, Buckley PA, Grossmann JG, McEwan PA, et al. 2003c. Structure of an integrin-ligand complex deduced from solution x-ray scattering and site-directed mutagenesis. J. Biol. Chem. 278:39993-99
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 39993-39999
-
-
Mould, A.P.1
Symonds, E.J.2
Buckley, P.A.3
Grossmann, J.G.4
McEwan, P.A.5
-
73
-
-
0024293497
-
Electron microscopy and structural model of human fibronectin receptor
-
Nermut MV, Green NM, Eason P, Yamada SS, Yamada KM. 1988. Electron microscopy and structural model of human fibronectin receptor. EMBO J. 7:4093-99
-
(1988)
EMBO J.
, vol.7
, pp. 4093-4099
-
-
Nermut, M.V.1
Green, N.M.2
Eason, P.3
Yamada, S.S.4
Yamada, K.M.5
-
74
-
-
14844323604
-
Transmembrane domain helix packing stabilizes integrin alpha IIb beta 3 in the low affinity state
-
Partridge AW, Liu S, Kim S, Bowie JU, Ginsberg MH. 2004. Transmembrane domain helix packing stabilizes integrin alpha IIb beta 3 in the low affinity state. J. Biol. Chem. 280:7294-300
-
(2004)
J. Biol. Chem.
, vol.280
, pp. 7294-7300
-
-
Partridge, A.W.1
Liu, S.2
Kim, S.3
Bowie, J.U.4
Ginsberg, M.H.5
-
75
-
-
2642531060
-
SRC-dependent outside-in signaling is a key step in the process of auto-regulation of beta2 integrins in polymorphonuclear leukocytes
-
Piccardoni P, Manarini S, Federico L, Bagoly Z, Pecce R, et al. 2004. SRC-dependent outside-in signaling is a key step in the process of auto-regulation of beta2 integrins in polymorphonuclear leukocytes. Biochem J. 380(Pt. 1):57-65
-
(2004)
Biochem J.
, vol.380
, Issue.PART 1
, pp. 57-65
-
-
Piccardoni, P.1
Manarini, S.2
Federico, L.3
Bagoly, Z.4
Pecce, R.5
-
76
-
-
0028822128
-
Crystal structure of the I-domain from the CD 11a/CD18 (LFA-1, αLβ2) integrin
-
Qu A, Leahy DJ. 1995. Crystal structure of the I-domain from the CD 11a/CD18 (LFA-1, αLβ2) integrin. Proc. Natl. Acad. Sci. 92:10277-81
-
(1995)
Proc. Natl. Acad. Sci.
, vol.92
, pp. 10277-10281
-
-
Qu, A.1
Leahy, D.J.2
-
77
-
-
0030586822
-
The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin
-
Qu A, Leahy DJ. 1996. The role of the divalent cation in the structure of the I domain from the CD11a/CD18 integrin. Structure 4:931-42
-
(1996)
Structure
, vol.4
, pp. 931-942
-
-
Qu, A.1
Leahy, D.J.2
-
78
-
-
1642342987
-
Pulling back to move forward
-
Ridley AJ. 2004. Pulling back to move forward. Cell 116:357-58
-
(2004)
Cell
, vol.116
, pp. 357-358
-
-
Ridley, A.J.1
-
79
-
-
0344305784
-
Cell migration: Integrating signals from front to back
-
Ridley AJ, Schwartz MA, Burridge K, Firtel RA, Ginsberg MH, et al. 2003. Cell migration: integrating signals from front to back. Science 302:1704-9
-
(2003)
Science
, vol.302
, pp. 1704-1709
-
-
Ridley, A.J.1
Schwartz, M.A.2
Burridge, K.3
Firtel, R.A.4
Ginsberg, M.H.5
-
80
-
-
0030039741
-
Solvent accessible residues on the MIDAS face of integrin CR3 mediate its binding to the neutrophil adhesion inhibitor NIF
-
Rieu P, Sugimori T, Griffith DL, Arnaout MA. 1996. Solvent accessible residues on the MIDAS face of integrin CR3 mediate its binding to the neutrophil adhesion inhibitor NIF. J. Biol. Chem. 271:15858-61
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 15858-15861
-
-
Rieu, P.1
Sugimori, T.2
Griffith, D.L.3
Arnaout, M.A.4
-
82
-
-
0032509204
-
Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin
-
Sampath R, Gallagher PJ, Pavalko FM. 1998. Cytoskeletal interactions with the leukocyte integrin beta2 cytoplasmic tail. Activation-dependent regulation of associations with talin and alpha-actinin. J. Biol. Chem. 273:33588-94
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33588-33594
-
-
Sampath, R.1
Gallagher, P.J.2
Pavalko, F.M.3
-
83
-
-
0036229694
-
Networks and crosstalk: Integrin signalling spreads
-
Schwartz MA, Ginsberg MH. 2002. Networks and crosstalk: integrin signalling spreads. Nat. Cell Biol. 4:E65-68
-
(2002)
Nat. Cell Biol.
, vol.4
-
-
Schwartz, M.A.1
Ginsberg, M.H.2
-
84
-
-
0036009116
-
Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling
-
Sebzda E, Bracke M, Tugal T, Hogg N, Cantrell DA. 2002. Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling. Nat. Immunol. 3:251-58
-
(2002)
Nat. Immunol.
, vol.3
, pp. 251-258
-
-
Sebzda, E.1
Bracke, M.2
Tugal, T.3
Hogg, N.4
Cantrell, D.A.5
-
85
-
-
4143085058
-
Folding of helical membrane proteins: The role of polar, GxxxG-like and proline motifs
-
Senes A, Engel DE, DeGrado WF. 2004. Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs. Curr. Opin. Struct. Biol. 14:465-79
-
(2004)
Curr. Opin. Struct. Biol.
, vol.14
, pp. 465-479
-
-
Senes, A.1
Engel, D.E.2
Degrado, W.F.3
-
86
-
-
0141746138
-
Small molecule integrin antagonists that bind to the beta2 subunit I-like domain and activate signals in one direction and block them in the other
-
Shimaoka M, Salas A, Yang W, Weitz-Schmidt G, Springer TA. 2003a. Small molecule integrin antagonists that bind to the beta2 subunit I-like domain and activate signals in one direction and block them in the other. Immunity 19:391-402
-
(2003)
Immunity
, vol.19
, pp. 391-402
-
-
Shimaoka, M.1
Salas, A.2
Yang, W.3
Weitz-Schmidt, G.4
Springer, T.A.5
-
87
-
-
0037428080
-
Structures of the alphaL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation
-
Shimaoka M, Xiao T, Liu JH, Yang Y, Dong Y, et al. 2003 b. Structures of the alphaL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation. Cell 112:99-111
-
(2003)
Cell
, vol.112
, pp. 99-111
-
-
Shimaoka, M.1
Xiao, T.2
Liu, J.H.3
Yang, Y.4
Dong, Y.5
-
88
-
-
0038561221
-
Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow
-
Shimonaka M, Katagiri K, Nakayama T, Fujita N, Tsuruo T, et al. 2003. Rap1 translates chemokine signals to integrin activation, cell polarization, and motility across vascular endothelium under flow. J. Cell Biol. 161:417-27
-
(2003)
J. Cell Biol.
, vol.161
, pp. 417-427
-
-
Shimonaka, M.1
Katagiri, K.2
Nakayama, T.3
Fujita, N.4
Tsuruo, T.5
-
89
-
-
0034616388
-
Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function
-
Simon DI, Wei Y, Zhang L, Rao NK, Xu H, et al. 2000. Identification of a urokinase receptor-integrin interaction site. Promiscuous regulator of integrin function. J. Biol. Chem. 275:10228-34
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10228-10234
-
-
Simon, D.I.1
Wei, Y.2
Zhang, L.3
Rao, N.K.4
Xu, H.5
-
90
-
-
0032763190
-
A direct comparison of selectin-mediated transient, adhesive events using high temporal resolution
-
Smith MJ, Berg EL, Lawrence MB. 1999. A direct comparison of selectin-mediated transient, adhesive events using high temporal resolution. Biophys. J. 77:3371-83
-
(1999)
Biophys. J.
, vol.77
, pp. 3371-3383
-
-
Smith, M.J.1
Berg, E.L.2
Lawrence, M.B.3
-
91
-
-
0031013031
-
Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain
-
Springer TA. 1997. Folding of the N-terminal, ligand-binding region of integrin alpha-subunits into a beta-propeller domain. Proc. Natl. Acad. Sci. USA 94:65-72
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 65-72
-
-
Springer, T.A.1
-
92
-
-
2442694279
-
Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits
-
Stefansson A, Armulik A, Nilsson I, von Heijne G, Johansson S. 2004. Determination of N- and C-terminal borders of the transmembrane domain of integrin subunits. J. Biol. Chem. 279:21200-5
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 21200-21205
-
-
Stefansson, A.1
Armulik, A.2
Nilsson, I.3
Von Heijne, G.4
Johansson, S.5
-
93
-
-
0141865705
-
Talin binding to integrin beta tails: A final common step in integrin activation
-
Tadokoro S, Shattil SJ, Eto K, Tai V, Liddington RC, et al. 2003. Talin binding to integrin beta tails: a final common step in integrin activation. Science 302:103-6
-
(2003)
Science
, vol.302
, pp. 103-106
-
-
Tadokoro, S.1
Shattil, S.J.2
Eto, K.3
Tai, V.4
Liddington, R.C.5
-
94
-
-
0037006979
-
The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding
-
Takagi J, DeBottis DP, Erickson HP, Springer TA. 2002a. The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding. Biochemistry 41:4339-47
-
(2002)
Biochemistry
, vol.41
, pp. 4339-4347
-
-
Takagi, J.1
DeBottis, D.P.2
Erickson, H.P.3
Springer, T.A.4
-
95
-
-
0037031906
-
Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling
-
Takagi J, Petre BM, Walz T, Springer TA. 2002b. Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling. Cell 110:599-11
-
(2002)
Cell
, vol.110
, pp. 599-611
-
-
Takagi, J.1
Petre, B.M.2
Walz, T.3
Springer, T.A.4
-
96
-
-
0141625303
-
Structure of integrin alpha 5 beta 1 in complex with fibronectin
-
Takagi J, Strokovich K, Springer TA, Walz T. 2003. Structure of integrin alpha 5 beta 1 in complex with fibronectin. EMBO J. 22:4607-15
-
(2003)
EMBO J.
, vol.22
, pp. 4607-4615
-
-
Takagi, J.1
Strokovich, K.2
Springer, T.A.3
Walz, T.4
-
97
-
-
0034283664
-
Effect of integrin beta 2 subunit truncations on LEA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) assembly, surface expression, and function
-
Tan SM, Hyland RH, Al-Shamkhani A, Douglass WA, Shaw JM, Law SK. 2000. Effect of integrin beta 2 subunit truncations on LEA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18) assembly, surface expression, and function. J. Immunol. 165:2574-81
-
(2000)
J. Immunol.
, vol.165
, pp. 2574-2581
-
-
Tan, S.M.1
Hyland, R.H.2
Al-Shamkhani, A.3
Douglass, W.A.4
Shaw, J.M.5
Law, S.K.6
-
98
-
-
11144232877
-
The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain
-
Tng E, Tan SM, Ranganathan S, Cheng M, Law SK. 2004. The integrin alpha L beta 2 hybrid domain serves as a link for the propagation of activation signal from its stalk regions to the I-like domain. J. Biol. Chem. 279:54334-39
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 54334-54339
-
-
Tng, E.1
Tan, S.M.2
Ranganathan, S.3
Cheng, M.4
Law, S.K.5
-
99
-
-
0038503260
-
Domain-specific interactions of talin with the membrane-proximal region of the integrin beta 3 subunit
-
Ulmer TS, Calderwood DA, Ginsberg MH, Campbell ID. 2003. Domain-specific interactions of talin with the membrane-proximal region of the integrin beta 3 subunit. Biochemistry 42:8307-12
-
(2003)
Biochemistry
, vol.42
, pp. 8307-8312
-
-
Ulmer, T.S.1
Calderwood, D.A.2
Ginsberg, M.H.3
Campbell, I.D.4
-
100
-
-
0035954396
-
NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution
-
Ulmer TS, Yaspan B, Ginsberg MH, Campbell ID. 2001. NMR analysis of structure and dynamics of the cytosolic tails of integrin alpha IIb beta 3 in aqueous solution. Biochemistry 40:7498-508
-
(2001)
Biochemistry
, vol.40
, pp. 7498-7508
-
-
Ulmer, T.S.1
Yaspan, B.2
Ginsberg, M.H.3
Campbell, I.D.4
-
101
-
-
0028176149
-
2+ modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion
-
2+ modulates leukocyte function-associated antigen-1 cell surface distribution on T lymphocytes and consequently affects cell adhesion. J. Cell Biol. 124:1061-70
-
(1994)
J. Cell Biol.
, vol.124
, pp. 1061-1070
-
-
Kooyk, Y.1
Weder, P.2
Heiji, K.3
Figdor, C.G.4
-
102
-
-
1642529548
-
Membrane-mediated structural transitions at the cytoplasmic face during integrin activation
-
Vinogradova O, Vaynberg J, Kong X, Haas TA, Plow EF, Qin J. 2004. Membrane-mediated structural transitions at the cytoplasmic face during integrin activation. Proc. Natl. Acad. Sci. USA 101:4094-99
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4094-4099
-
-
Vinogradova, O.1
Vaynberg, J.2
Kong, X.3
Haas, T.A.4
Plow, E.F.5
Qin, J.6
-
103
-
-
0037031551
-
A structural mechanism of integrin alpha(IIb)beta(3) "inside- out" activation as regulated by its cytoplasmic face
-
Vinogradova O, Velyvis A, Velyviene A, Hu B, Haas T, et al. 2002. A structural mechanism of integrin alpha(IIb)beta(3) "inside-out" activation as regulated by its cytoplasmic face. Cell 110:587-97
-
(2002)
Cell
, vol.110
, pp. 587-597
-
-
Vinogradova, O.1
Velyvis, A.2
Velyviene, A.3
Hu, B.4
Haas, T.5
-
104
-
-
0141865507
-
Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2
-
von Wiehert G, Haimovich B, Feng GS, Sheetz MP. 2003. Force-dependent integrin-cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2. EMBO J. 22:5023-35
-
(2003)
EMBO J.
, vol.22
, pp. 5023-5035
-
-
Von Wiehert, G.1
Haimovich, B.2
Feng, G.S.3
Sheetz, M.P.4
-
105
-
-
0037452666
-
Structure and allosteric regulation of the alpha X beta 2 integrin I domain
-
Vorup-Jensen T, Ostermeier C, Shimaoka M, Hommel U, Springer TA. 2003. Structure and allosteric regulation of the alpha X beta 2 integrin I domain. Proc. Natl. Acad. Sci. US 100:1873-78
-
(2003)
Proc. Natl. Acad. Sci. US
, vol.100
, pp. 1873-1878
-
-
Vorup-Jensen, T.1
Ostermeier, C.2
Shimaoka, M.3
Hommel, U.4
Springer, T.A.5
-
106
-
-
0035166327
-
Dual role of H-Ras in regulation of lymphocyte function antigen-1 activity by stromal cell-derived factor-1 alpha: Implications for leukocyte transmigration
-
Weber KS, Ostermann G, Zernecke A, Schroder A, Klickstein LB, Weber C. 2001a. Dual role of H-Ras in regulation of lymphocyte function antigen-1 activity by stromal cell-derived factor-1 alpha: implications for leukocyte transmigration. Mol. Biol. Cell 12:3074-86
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 3074-3086
-
-
Weber, K.S.1
Ostermann, G.2
Zernecke, A.3
Schroder, A.4
Klickstein, L.B.5
Weber, C.6
-
107
-
-
0035846547
-
Cytohesin-1 is a dynamic regulator of distinct LFA-1 functions in leukocyte arrest and transmigration triggered by chemokines
-
Weber KS, Weber C, Ostermann G, Dierks H, Nagel W, Kolanus W. 2001b. Cytohesin-1 is a dynamic regulator of distinct LFA-1 functions in leukocyte arrest and transmigration triggered by chemokines. Curr. Biol. 11:1969-74
-
(2001)
Curr. Biol.
, vol.11
, pp. 1969-1974
-
-
Weber, K.S.1
Weber, C.2
Ostermann, G.3
Dierks, H.4
Nagel, W.5
Kolanus, W.6
-
108
-
-
13444274458
-
Regulation of alpha 5 beta 1 integrin conformation and function by urokinase receptor binding
-
Wei Y, Czekay RP, Robillard L, Kugler MC, Zhang F, et al. 2005. Regulation of alpha 5 beta 1 integrin conformation and function by urokinase receptor binding. J. Cell Biol. 168:501-11
-
(2005)
J. Cell Biol.
, vol.168
, pp. 501-511
-
-
Wei, Y.1
Czekay, R.P.2
Robillard, L.3
Kugler, M.C.4
Zhang, F.5
-
109
-
-
8744221687
-
Improved lymphocyte function-associated antigen-1 (LEA-1) inhibition by statin derivatives: Molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo
-
Weitz-Schmidt G, Welzenbach K, Dawson J, Kallen J. 2004. Improved lymphocyte function-associated antigen-1 (LEA-1) inhibition by statin derivatives: molecular basis determined by x-ray analysis and monitoring of LFA-1 conformational changes in vitro and ex vivo. J. Biol. Chem. 279:46764-71
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 46764-46771
-
-
Weitz-Schmidt, G.1
Welzenbach, K.2
Dawson, J.3
Kallen, J.4
-
110
-
-
0037197990
-
Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- And beta 3-subunits
-
Weljie AM, Hwang PM, Vogel HJ. 2002. Solution structures of the cytoplasmic tail complex from platelet integrin alpha IIb- and beta 3-subunits. Proc. Natl. Acad. Sci. USA 99:5878-83
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5878-5883
-
-
Weljie, A.M.1
Hwang, P.M.2
Vogel, H.J.3
-
111
-
-
0037155873
-
Small molecule inhibitors induce conformational changes in the I domain and the I-like domain of lymphocyte function-associated antigen-1. Molecular insights into integrin inhibition
-
Welzenbach K, Hommel U, Weitz-Schmidt G. 2002. Small molecule inhibitors induce conformational changes in the I domain and the I-like domain of lymphocyte function-associated antigen-1. Molecular insights into integrin inhibition. J. Biol. Chem. 277:10590-98
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 10590-10598
-
-
Welzenbach, K.1
Hommel, U.2
Weitz-Schmidt, G.3
-
112
-
-
0036796740
-
Distribution and evolution of von Willebrand/integrin a domains: Widely dispersed domains with roles in cell adhesion and elsewhere
-
Whittaker CA, Hynes RO. 2002. Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere. Mol. Biol. Cell 13:3369-87
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3369-3387
-
-
Whittaker, C.A.1
Hynes, R.O.2
-
113
-
-
0029671071
-
Control of beta1 integrin function. Localization of stimulatory epitopes
-
Wilkins JA, Li A, Ni H, Stupack DG, Shen C. 1996. Control of beta1 integrin function. Localization of stimulatory epitopes. J. Biol. Chem. 271:3046-51
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 3046-3051
-
-
Wilkins, J.A.1
Li, A.2
Ni, H.3
Stupack, D.G.4
Shen, C.5
-
114
-
-
8544259562
-
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics
-
Xiao T, Takagi J, Coller BS, Wang JH, Springer TA. 2004. Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics. Nature 432:59-67
-
(2004)
Nature
, vol.432
, pp. 59-67
-
-
Xiao, T.1
Takagi, J.2
Coller, B.S.3
Wang, J.H.4
Springer, T.A.5
-
115
-
-
0034624058
-
An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain
-
Xiong JP, Li R, Essafi M, Stehle T, Arnaout MA. 2000. An isoleucine-based allosteric switch controls affinity and shape shifting in integrin CD11b A-domain. J. Biol. Chem. 275:38762-67
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38762-38767
-
-
Xiong, J.P.1
Li, R.2
Essafi, M.3
Stehle, T.4
Arnaout, M.A.5
-
116
-
-
0035850669
-
Crystal structure of the extracellular segment of integrin alpha Vbeta3
-
Xiong JP, Stehle T, Diefenbach B, Zhang R, Dunker R, et al. 2001. Crystal structure of the extracellular segment of integrin alpha Vbeta3. Science 294:339-45
-
(2001)
Science
, vol.294
, pp. 339-345
-
-
Xiong, J.P.1
Stehle, T.2
Diefenbach, B.3
Zhang, R.4
Dunker, R.5
-
117
-
-
0042739086
-
New insights into the structural basis of integrin activation
-
Xiong JP, Stehle T, Goodman SL, Arnaout MA. 2003. New insights into the structural basis of integrin activation. Blood 102:1155-59
-
(2003)
Blood
, vol.102
, pp. 1155-1159
-
-
Xiong, J.P.1
Stehle, T.2
Goodman, S.L.3
Arnaout, M.A.4
-
118
-
-
4644272216
-
A novel adaptation of the integrin PSI domain revealed from its crystal structure
-
Xiong JP, Stehle T, Goodman SL, Arnaout MA. 2004. A novel adaptation of the integrin PSI domain revealed from its crystal structure. J. Biol. Chem. 279:40252-54
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 40252-40254
-
-
Xiong, J.P.1
Stehle, T.2
Goodman, S.L.3
Arnaout, M.A.4
-
119
-
-
0037023363
-
Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand
-
Xiong JP, Stehle T, Zhang R, Joachimiak A, Frech M, et al. 2002. Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand. Science 296:151-55
-
(2002)
Science
, vol.296
, pp. 151-155
-
-
Xiong, J.P.1
Stehle, T.2
Zhang, R.3
Joachimiak, A.4
Frech, M.5
-
120
-
-
0035958967
-
Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain
-
Yan B, Calderwood DA, Yaspan B, Ginsberg MH. 2001. Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain. J. Biol. Chem. 276:28164-70
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28164-28170
-
-
Yan, B.1
Calderwood, D.A.2
Yaspan, B.3
Ginsberg, M.H.4
-
121
-
-
0034629281
-
Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3)
-
Yan B, Hu DD, Knowles SK, Smith JW. 2000. Probing chemical and conformational differences in the resting and active conformers of platelet integrin alpha(IIb)beta(3). J. Biol. Chem. 275:7249-60
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 7249-7260
-
-
Yan, B.1
Hu, D.D.2
Knowles, S.K.3
Smith, J.W.4
-
122
-
-
1442306162
-
Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions
-
Yang W, Shimaoka M, Chen J, Springer TA. 2004. Activation of integrin beta-subunit I-like domains by one-turn C-terminal alpha-helix deletions. Proc. Natl. Acad. Sci. USA 101:2333-38
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 2333-2338
-
-
Yang, W.1
Shimaoka, M.2
Chen, J.3
Springer, T.A.4
-
123
-
-
0033594871
-
Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi
-
Zhang L, Plow EF. 1999. Amino acid sequences within the alpha subunit of integrin alpha M beta 2 (Mac-1) critical for specific recognition of C3bi. Biochemistry 38:8064-71
-
(1999)
Biochemistry
, vol.38
, pp. 8064-8071
-
-
Zhang, L.1
Plow, E.F.2
-
124
-
-
0036789541
-
Force spectroscopy of the leukocyte function-associated antigen-I/intercellular adhesion molecule-1 interaction
-
Zhang X, Wojcikiewicz E, Moy VT. 2002. Force spectroscopy of the leukocyte function-associated antigen-I/intercellular adhesion molecule-1 interaction. Biophys. J. 83:2270-79
-
(2002)
Biophys. J.
, vol.83
, pp. 2270-2279
-
-
Zhang, X.1
Wojcikiewicz, E.2
Moy, V.T.3
-
125
-
-
1142274294
-
Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stress
-
Zwartz G, Chigaev A, Foutz T, Larson RS, Posner R, Sklar LA. 2004a. Relationship between molecular and cellular dissociation rates for VLA-4/VCAM-1 interaction in the absence of shear stress. Biophys. J. 86:1243-52
-
(2004)
Biophys. J.
, vol.86
, pp. 1243-1252
-
-
Zwartz, G.1
Chigaev, A.2
Foutz, T.3
Larson, R.S.4
Posner, R.5
Sklar, L.A.6
-
126
-
-
4644269513
-
Real-time analysis of very late antigen-4 affinity modulation by shear
-
Zwartz GJ, Chigaev A, Dwyer DC, Foutz TD, Edwards BS, Sklar LA. 2004b. Real-time analysis of very late antigen-4 affinity modulation by shear. J. Biol. Chem. 279:38277-86
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 38277-38286
-
-
Zwartz, G.J.1
Chigaev, A.2
Dwyer, D.C.3
Foutz, T.D.4
Edwards, B.S.5
Sklar, L.A.6
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