Talin binding to integrin β tails: A final common step in integrin activation

Science

Volumn 302, Issue 5642, 2003, Pages 103-106

  Tadokoro, Seiji ^a   Shattil, Sanford J ^a   Eto, Koji ^a   Tai, Vera ^a   Liddington, Robert C ^b   De Pereda, José M ^b   Ginsberg, Mark H ^a   Calderwood, David A ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CYTOLOGY; PROTEINS;

CELL MIGRATION;

BIOCHEMISTRY;

ALPHA2B BETA3 INTEGRIN; BETA3 INTEGRIN; LIGAND; TALIN; UNCLASSIFIED DRUG;

LIGAND; PROTEIN;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL ADHESION; CELL MIGRATION; CHO CELL; CYTOPLASM; EXTRACELLULAR MATRIX; FEMALE; GENE ACTIVATION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD29; CELL LINE; FIBRONECTINS; HUMANS; INTEGRIN BETA CHAINS; INTEGRIN BETA3; MOLECULAR SEQUENCE DATA; MUTATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TALIN; TRANSFECTION;

ANIMALIA;

EID: 0141865705     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1086652     Document Type: Article

References (26)

1. S. P. Palecek, J. C. Loftus, M. H. Ginsberg, A. F. Horwitz, D. A. Lauffenburger, Nature 385, 537 (1997).
2. C. Wu, V. M. Keivens, T. E. O'Toole, J. A. McDonald, M. H. Ginsberg, Cell 83, 715 (1995).
3. R. O. Hynes, Cell 110, 673 (2002).
4. D. A. Calderwood et al., J. Biol. Chem. 274, 28071 (1999).
5. Materials and methods are available as supporting material on Science Online.
6. T. E. O'Toole et al., Science 254, 845 (1991).
7. P. J. Paddison, A. A. Caudy. E. Bernstein, G. J. Hannon, D. S. Conklin, Genes Dev. 16, 948 (2002).
8. A. L. Frelinger III, X. Du, E. F. Plow, M. H. Ginsberg, J. Biol. Chem. 266. 17106 (1991).
9. P. E. Hughes et al., J. Biol. Chem. 271, 6571 (1996).
10. T. E. O'Toole et al., J. Cell Biol. 124, 1047 (1994).
11. T. Hato, N. Pampori. S. J. Shattil, J. Cell Biol. 141, 1685 (1998).
12. N. Pampori et al., J. Biol. Chem. 274, 21609 (1999).
13. S. Tadokoro et al., data not shown.
14. K. Eto et al., Proc. Natl. Acad. Sci. U.S.A. 99, 12819 (2002).
15. H. Kashiwagi et al., J. Cell Biol. 137, 1433 (1997).
16. T. Sethi, M. H. Ginsberg, J. Downward, P. E. Hughes, Mol. Biol. Cell 10, 1799 (1999),
17. C. A. Fenczik, T. Sethi, J. W. Ramos, P. E. Hughes, M. H. Ginsberg, Nature 390, 81 (1997).
18. D. A. Calderwood et al., J. Biol. Chem. 277, 21749 (2002).
19. B. Garcia-Alvarez et al., Mol. Cell 11, 49 (2003).
20. D. A. Calderwood, S. J. Shattil, M. H. Ginsberg, J. Biol. Chem. 275. 22607 (2000).
21. P. Tapley, A. Horwitz, C. A. Buck, K. Duggan, L. Rohrschneider, Oncogene 4, 325 (1989).
22. B. Yan, D. A. Calderwood, B. Yaspan, M. H. Ginsberg, J. Biol. Chem. 276, 28164 (2001).
23. V. Martel et al., J. Biol. Chem. 276. 21217 (2001).
24. O. Vinogradova et al., Cell 110. 587 (2002).
25. J. Takagi, B. M. Petre, T. Walz, T. A. Springer, Cell 110. 599 (2002).
26. Supported by grants from the NIH and American Heart Association.