Transmembrane domain helix packing stabilizes integrin αIIbβ3 in the low affinity state

Journal of Biological Chemistry

Volumn 280, Issue 8, 2005, Pages 7294-7300

  Partridge, Anthony W ^a   Liu, Shouchun ^b   Kim, Sanguk ^c   Bowie, James U ^c   Ginsberg, Mark H ^a,d  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Nuvelo Inc   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESION; BIOCHEMISTRY; CELL MEMBRANES; COMPUTATIONAL METHODS; MOLECULAR BIOLOGY; MUTAGENESIS;

CELL MIGRATION; CYTOPLASMIC DOMAINS; HEMOSTASIS; IMMUNE RESPONSE;

PROTEINS;

BETA3 INTEGRIN; INTEGRIN; INTEGRIN ALPHAIIBBETA3; INTEGRIN RECEPTOR; MUTANT PROTEIN; UNCLASSIFIED DRUG;

ALPHA CHAIN; ANIMAL CELL; ARTICLE; BETA CHAIN; BINDING AFFINITY; CELL MIGRATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; HEMOSTASIS; IMMUNE RESPONSE; MOLECULAR INTERACTION; MUTAGENESIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STABILITY; RECEPTOR UPREGULATION;

EID: 14844323604     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412701200     Document Type: Article

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