Conformational changes in the integrin βA domain provide a mechanism for signal transduction via hybrid domain movement

Journal of Biological Chemistry

Volumn 278, Issue 19, 2003, Pages 17028-17035

  Mould, A Paul ^a   Barton, Stephanie J ^b   Askari, Janet A ^b   McEwan, Paul A ^b   Buckley, Patrick A ^b   Craig, Susan E ^b   Humphries, Martin J ^b  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; CONFORMATIONS; MOLECULAR BIOLOGY; MUTAGENESIS;

LIGANDS;

BIOCHEMISTRY;

CALCIUM ION; CATION; FIBRONECTIN; INTEGRIN; MAGNESIUM ION; MANGANESE; MONOCLONAL ANTIBODY; RECOMBINANT PROTEIN; VON WILLEBRAND FACTOR; BETA INTEGRIN; LIGAND;

ANIMAL CELL; ARTICLE; CHO CELL; EXTRACELLULAR MATRIX; GENE EXPRESSION; GENETIC TRANSFECTION; LIGAND BINDING; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; HAMSTER; HUMAN; PHYSIOLOGY; STRUCTURE ACTIVITY RELATION;

ANIMALIA;

ANIMALS; CHO CELLS; CRICETINAE; HUMANS; INTEGRIN BETA CHAINS; LIGANDS; MODELS, MOLECULAR; PROTEIN CONFORMATION; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0013307787     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M213139200     Document Type: Article

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