Crystal structure of the α1β1 integrin I domain in complex with an antibody Fab fragment

Journal of Molecular Biology

Volumn 327, Issue 5, 2003, Pages 1031-1041

  Karpusas, Michael ^a,b   Ferrant, Janine ^a   Weinreb, Paul H ^a   Carmillo, Amie ^a   Taylor, Frederick R ^a   Garber, Ellen A ^a  

^a BIOGEN   (United States)

^b Locus Pharmaceuticals Inc   (United States)

Author keywords

Collagen; Crystal structure; Epitope; Mutagenesis; VLA 1

Indexed keywords

ALANINE; ARGININE; ASPARTIC ACID; CHIMERIC PROTEIN; COLLAGEN; GLUTAMIC ACID; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN HEAVY CHAIN; METAL ION; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY AQC2; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 1; HYBRID PROTEIN;

ADHESION; AMINO ACID SUBSTITUTION; ANTIGEN ANTIBODY COMPLEX; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; HUMAN; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; RAT; CHEMISTRY; MUTAGENESIS; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INTEGRIN ALPHA1BETA1; MUTAGENESIS; PROTEIN CONFORMATION; RECOMBINANT FUSION PROTEINS;

EID: 0037432552     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00203-1     Document Type: Article

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