Agonist-specific structural rearrangements of integrin αIIbβ3. Confirmation of the bent conformation in platelets at rest and after activation

Journal of Biological Chemistry

Volumn 277, Issue 42, 2002, Pages 39899-39908

  Calzada, María J ^a   Alvarez, María V ^a   González Rodríguez, José ^a  

^a INSTITUTO DE QUÍMICA FÍSICA ROCASOLANO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY;

ALLOSTERIC EFFECTS; EPITOPE MAPS;

PROTEINS;

INTEGRIN; INTEGRIN ALPHA2B BETA3; MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTALLOGRAPHY; DISULFIDE BOND; HUMAN; HUMAN CELL; LIGAND BINDING; MOLECULAR MECHANICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN STRUCTURE; THROMBOCYTE ACTIVATION; ULTRASTRUCTURE;

ALLOSTERIC SITE; ANTIBODIES, MONOCLONAL; ANTIGENS; BINDING, COMPETITIVE; BLOOD PLATELETS; CELL MEMBRANE; EPITOPES; HUMANS; IMMUNOBLOTTING; KINETICS; LIGANDS; MODELS, MOLECULAR; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY;

EID: 0037131270     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205886200     Document Type: Article

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