Noninvasive prediction of fibrosis in C282Y homozygous hemochromatosis

Gastroenterology

Volumn 115, Issue 4, 1998, Pages 929-936

  Guyader, D ^a   Jacquelinet, C ^a   Moirand, R ^a   Turlin, B ^a   Mendler, M H ^a   Chaperon, J ^a   David, V ^a   Brissot, P ^a   Adams, P ^a   Deugnier, Y ^a  

^a PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN;

ADULT; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; DISEASE SEVERITY; FEMALE; FERRITIN BLOOD LEVEL; HEMOCHROMATOSIS; HEPATOSPLENOMEGALY; HUMAN; LIVER BIOPSY; LIVER FIBROSIS; LIVER FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 0031707469     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0016-5085(98)70265-3     Document Type: Article

References (40)

1. P Brissot Y Deugnier Genetic hemochromatosis N McIntyre J Benhamou J Bircher M Rizzetto J Rodes Oxford textbook of clinical hepatology 1998 Oxford University Press Oxford (in press)
2. C Niederau R Fischer A Purschel W Stremmel D Haussinger G Strohmeyer Long-term survival in patients with hereditary hemochromatosis Gastroenterology 110 1996 1107 1119
3. C Niederau R Fischer A Sonnenberg W Stremmel HJ Trampisch G Strohmeyer Survival and causes of death in cirrhotic and in noncirrhotic patients with primary hemochromatosis N Engl J Med 313 1985 1256 1262
4. RA Bradbear C Bain V Siskind FD Schofield S Webb EM Axelsen J Halliday ML Bassett LW Powell Cohort study of internal malignancy in genetic hemochromatosis and other chronic nonalcoholic liver diseases J Natl Cancer Inst 75 1985 81 84
5. Y Deugnier D Guyader L Crantock JM Lopez B Turlin J Yaouanq H Jouanolle JP Campion B Launois JW Halliday LW Powell P Brissot Primary liver cancer in genetic hemochromatosis: a clinical, pathological, and pathogenetic study of 54 cases Gastroenterology 104 1993 228 234
6. PC Adams M Speechley AE Kertesz Long-term survival analysis in hereditary hemochromatosis Gastroenterology 101 1991 368 372
7. BR Bacon Diagnosis and management of hemochromatosis Gastroenterology 113 1997 995 999
8. YM Deugnier O Loréal B Turlin D Guyader H Jouanolle R Moirand C Jacquelinet P Brissot Liver pathology in genetic hemochromatosis: a review of 135 homozygous cases and their bioclinical correlations Gastroenterology 102 1992 2050 2059
9. KV Kowdley TD Trainer JR Saltzman M Pedrosa EL Krawitt TA Knox K Susskind D Pratt HL Bonkovsky ND Grace MM Kaplan Utility of hepatic iron index in American patients with hereditary hemochromatosis: a multicenter study Gastroenterology 113 1997 1270 1277
10. ML Bassett JW Halliday LW Powell Value of hepatic iron measurements in early hemochromatosis and determination of the critical iron level associated with fibrosis Hepatology 6 1986 24 29
11. JN Feder A Gnirke W Thomas Z Tsuchihashi DA Ruddy A Basava F Dormishian R Domingo MC Ellis A Fullan LM Hinton NL Jones BE Kimmel IGS Dronmal P Lauer VK Lee DB Loeb FA Mapa E McClelland MC Meyer GA Mintier N Moeller T Moorz E Morikang CE Prass L Quintana SM Starnes RC Schatzman KJ Brunke DT Drayna NJ Risch BR Bacon RK Wolff A novel MHC class I–like gene is mutated in patients with hereditary haemochromatosis Nat Genet 13 1996 399 409
12. JG Bodmer P Parham E Albert S Marsh Putting a hold on HLA-H Nat Genet 15 1997 234 235
13. N Borot MP Roth L Malfroy C Demangel JP Vinel JP Pascal H Coppin Mutations in the MCH class I–like candidate gene for hemochomatosis in French patients Immunogenetics 45 1997 320 324
14. M Carella L D'ambrosio A Totaro A Grifa MA Valentino A Piperno D Girelli A Roetto B Franco P Gasparini C Camaschella Mutation analysis of the HLA-H gene in Italian hemochromatosis patients Am J Hum Genet 60 1997 828 832
15. JC Barton WWH Shih R Sawada-Hirai RT Acton L Harmon C Rivers BE Rothenberg Genetic and clinical description of hemochromatosis probands and heterozygotes: evidence that multiple genes linked to the major histocompatibility complex are responsible for hemochromatosis Blood Cells Mol Dis 23 1997 135 145
16. E Beutler T Gelbart C West P Lee M Adams R Blackstone P Pockros M Kosty CP Venditti PD Phatak NK Seese KA Chorney AE Ten Elshof GS Gerhard M Chorney Mutation analysis in hereditary hemochromatosis Blood Cells Mol Dis 22 1996 187 194
17. AM Jouanolle P Fergelot G Gandon J Yaouanq JY Le Gall V David A candidate gene for hemochromatosis: frequency of the C282Y and H63D mutations Human Genet 100 1997 544 547
18. EC Jazwinska LM Cullen F Busfield WR Pyper SI Webb LW Powell CP Morris TP Walsh Hæmochromatosis and HLA-H Nat Genet 14 1996 249 251
19. AM Jouanolle G Gandon P Jezequel M Blayau ML Campion J Yaouanq J Mosser P Fergelot B Chauvel P Bouric G Carn N Andrieux I Gicquel JY Le Gall V David Hæmochromatosis and HLA-H Nat Genet 14 1996 251 252
20. G Garcia-Tsao JL Boyer Outpatient liver biopsy: how safe is it? Ann Intern Med 118 1993 150 153
21. F Piccinino E Sagnelli G Pasquale G Giusti Complications following percutaneous liver biopsy: a multicenter retrospective study on 68, 276 biopsies J Hepatol 2 1986 165 173
22. M Barr y S Sherlock Measurement of liver-iron concentration in needle-biopsy specimens Lancet 2 1971 100 103
23. SW Schalm The diagnosis of cirrhosis: clinical relevance and methodology J Hepatol 27 1997 1118 1119
24. YM Deugnier P Charalambous D Le Quilleuc B Turlin J Searle P Brissot LW Powell JW Halliday Preneoplastic significance of hepatic iron-free foci in genetic hemochromatosis: a study of 185 patients Hepatology 18 1993 1363 1369
25. WP Baldus VF Fairbanks TP Moyer Predicting phlebotomy requirements in genetic hemochromatosis (abstr) Proceedings of fifth conference of the International Association for the Study of Disorders of Iron Metabolism 1995 67
26. HL Bonkovsky DP Slaker EB Bills DC Wolf Usefulness and limitations of laboratory and hepatic imaging studies in iron-storage disease Gastroenterology 99 1990 1079 1091
27. Y Gandon D Guyader JF Heautot MI Reda J Yaouanq T Buhe P Brissot M Carsin Y Deugnier Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging Radiology 193 1994 533 538
28. O Loréal Y Deugnier R Moirand L Lauvin D Guyader H Jouanolle B Turlin G Lescoat P Brissot Liver fibrosis in genetic hemochromatosis: respective roles of iron and noniron related factors in 127 homozygous patients J Hepatol 16 1992 122 127
29. A Pietrangelo Iron, oxidative stress and liver fibrosis J Hepatol 28 1998 8 13
30. P Brissot R Moirand AM Jouanolle D Guyader JY Le Gall Y Deugnier V David A genotypic study of 207 unrelated probands diagnosed as “genetic hemochromatosis” on “classical” phenotypic criteria (abstr) Hepatology 26 1997 370A
31. AT Merryweather-Clarke JJ Pointon JD Shearman KJH Robson Global prevalence of putative haemochromatosis mutations J Med Genet 34 1997 275 278
32. PC Adams S Chakrabarti Genotypic/phenotypic correlations in genetic hemochromatosis: evolution of diagnostic criteria Gastroenterology 114 1998 319 323
33. AS Tavill BK Sharma BR Bacon Iron and the liver: genetic hemochromatosis and other hepatic overload disorders Prog Liver Dis 9 1990 281 305
34. J Ludwig E Hashimoto MK Porayko TP Moyer WP Baldus Hemosiderosis in cirrhosis: a study of 447 native livers Gastroenterology 112 1997 882 888
35. Y Deugnier B Turlin D Le Quilleuc R Moirand O Loréal M Messner B Meunier P Brissot B Launois A reappraisal of hepatic siderosis in patients with end-stage cirrhosis: practical implications for the diagnosis of hemochromatosis Am J Surg Pathol 21 1997 669 675
36. JP Villeneuve M Bilodeau R Lepage J Côté M Lefebvre Variability in hepatic iron concentration measurements from needle-biopsy specimens J Hepatol 25 1996 172 177
37. R Moirand M Abdel Majid O Loréal F Paillard P Brissot Y Deugnier A new syndrome of liver iron overload with normal transferrin saturation Lancet 349 1997 95 97
38. HL Bonkovsky BF Banner AL Rothman Iron and chronic viral hepatitis Hepatology 25 1997 759 768
39. DHG Crawford EC Jazwinska LM Cullen LW Powell Expression of HLA-linked haemochromatosis in homozygous and heterozygous subjects diagnosed according to the C282Y mutation: evaluation of previous diagnostic criteria (abstr) Hepatology 26 1997 198A
40. PC Adams S Chakrabarti Genotypic/phenotypic correlations in genetic hemochromatosis: evolution of diagnostic criteria Gastroenterology 114 1998 319 323