메뉴 건너뛰기




Volumn 25, Issue 5, 1996, Pages 677-683

Hepatic stellate cell activation occurs in the absence of hepatitis in alcoholic liver disease and correlates with the severity of steatosis

Author keywords

Alcoholic fatty liver; Alcoholic liver disease; Fat storing cell; Hepatic stellate cell

Indexed keywords

ALCOHOL LIVER DISEASE; ALCOHOL METABOLISM; ALCOHOLISM; ARTICLE; CELL ACTIVITY; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; HEPATITIS; HUMAN; KUPFFER CELL; LIPID PEROXIDATION; LIVER BIOPSY; LIVER CELL; LIVER CIRRHOSIS; PRIORITY JOURNAL; STEATOSIS; STELLATE CELL;

EID: 0030296956     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-8278(96)80238-8     Document Type: Article
Times cited : (136)

References (52)
  • 1
    • 0025357423 scopus 로고
    • Cellular sources of collagen and regulation of collagen production in liver
    • 1. Friedman SL. Cellular sources of collagen and regulation of collagen production in liver. Semin Liver Dis 1990; 10: 20-9.
    • (1990) Semin Liver Dis , vol.10 , pp. 20-29
    • Friedman, S.L.1
  • 2
    • 0027177097 scopus 로고
    • Cellular and molecular aspects of hepatic fibrosis
    • 2. Burt AD. Cellular and molecular aspects of hepatic fibrosis. J Pathol 1993; 170: 105-14.
    • (1993) J Pathol , vol.170 , pp. 105-114
    • Burt, A.D.1
  • 4
    • 0023901817 scopus 로고
    • Immunolocalization of laminin in normal rat liver and biosynthesis of laminin by hepatic lipocytes in primary culture
    • 4. Maher JJ, Friedman SL, Roll FJ, Bissell DM. Immunolocalization of laminin in normal rat liver and biosynthesis of laminin by hepatic lipocytes in primary culture. Gastroenterology 1988; 94: 1053-62.
    • (1988) Gastroenterology , vol.94 , pp. 1053-1062
    • Maher, J.J.1    Friedman, S.L.2    Roll, F.J.3    Bissell, D.M.4
  • 5
    • 0023412675 scopus 로고
    • Sinusoidal endothelial cells from guinea pig liver synthesize and secrete cellular fibronectin in vitro
    • 5. Rieder H, Ramadori G, Dienes HP, Meyer zum Buschenfelde KH. Sinusoidal endothelial cells from guinea pig liver synthesize and secrete cellular fibronectin in vitro. Hepatology 1987; 7: 856-64.
    • (1987) Hepatology , vol.7 , pp. 856-864
    • Rieder, H.1    Ramadori, G.2    Dienes, H.P.3    Meyer Zum Buschenfelde, K.H.4
  • 6
    • 0023804960 scopus 로고
    • Formation of extracellular matrix in normal rat liver: Lipocytes as a major source of proteoglycan
    • 6. Arenson DM, Friedman SL, Bissell DM. Formation of extracellular matrix in normal rat liver: lipocytes as a major source of proteoglycan. Gastroenterology 1988; 95: 441-7.
    • (1988) Gastroenterology , vol.95 , pp. 441-447
    • Arenson, D.M.1    Friedman, S.L.2    Bissell, D.M.3
  • 7
    • 0023275798 scopus 로고
    • The synthesis of proteoglycans in fat-storing cells of rat liver
    • 7. Schafer S, Zerbe O, Gressner AM. The synthesis of proteoglycans in fat-storing cells of rat liver. Hepatology 1987; 7: 680-7.
    • (1987) Hepatology , vol.7 , pp. 680-687
    • Schafer, S.1    Zerbe, O.2    Gressner, A.M.3
  • 8
    • 0026579161 scopus 로고
    • Macrophage and perisinusoidal cell kinetics in acute liver injury
    • 8. Johnson SJ, Hines JE, Burt AD. Macrophage and perisinusoidal cell kinetics in acute liver injury. J Pathol 1992; 166: 351-8.
    • (1992) J Pathol , vol.166 , pp. 351-358
    • Johnson, S.J.1    Hines, J.E.2    Burt, A.D.3
  • 9
    • 0027404472 scopus 로고
    • In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury
    • 9. Hines JE, Johnson SJ, Burt AD. In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury. Am J Pathol 1993; 142: 511-8.
    • (1993) Am J Pathol , vol.142 , pp. 511-518
    • Hines, J.E.1    Johnson, S.J.2    Burt, A.D.3
  • 10
    • 0024852111 scopus 로고
    • Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors
    • 10. Friedman SL, Arthur MJ. Activation of cultured rat hepatic lipocytes by Kupffer cell conditioned medium. Direct enhancement of matrix synthesis and stimulation of cell proliferation via induction of platelet-derived growth factor receptors. J Clin Invest 1989; 84: 1780-5.
    • (1989) J Clin Invest , vol.84 , pp. 1780-1785
    • Friedman, S.L.1    Arthur, M.J.2
  • 11
    • 0025272680 scopus 로고
    • Sensitisation of hepatic lipocytes by high fat diet to stimulatory effects of Kupffer cell-derived factors: Implications for fibrogenesis
    • 11. Matsuoka M, Zhang MY, Tsukamoto H. Sensitisation of hepatic lipocytes by high fat diet to stimulatory effects of Kupffer cell-derived factors: implications for fibrogenesis. Hepatology 1990; 11: 173-82.
    • (1990) Hepatology , vol.11 , pp. 173-182
    • Matsuoka, M.1    Zhang, M.Y.2    Tsukamoto, H.3
  • 12
    • 0024516970 scopus 로고
    • Differential effects of interleukin-1 alpha, tumor necrosis factor alpha, and transforming growth factor beta 1 on cell proliferation and collagen formation by cultured fat-storing cells
    • 12. Matsuoka M, Pham NT, Tsukamoto H. Differential effects of interleukin-1 alpha, tumor necrosis factor alpha, and transforming growth factor beta 1 on cell proliferation and collagen formation by cultured fat-storing cells. Liver 1989; 9: 71-8.
    • (1989) Liver , vol.9 , pp. 71-78
    • Matsuoka, M.1    Pham, N.T.2    Tsukamoto, H.3
  • 13
    • 0027397539 scopus 로고
    • Tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta 1 (TGF beta 1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts
    • 13. Bachem MG, Sell KM, Melchior R, Kropf J, Eller T, Gressner AM. Tumor necrosis factor alpha (TNF alpha) and transforming growth factor beta 1 (TGF beta 1) stimulate fibronectin synthesis and the transdifferentiation of fat-storing cells in the rat liver into myofibroblasts. Virchows Arch B Cell Pathol 1993; 63: 123-30.
    • (1993) Virchows Arch B Cell Pathol , vol.63 , pp. 123-130
    • Bachem, M.G.1    Sell, K.M.2    Melchior, R.3    Kropf, J.4    Eller, T.5    Gressner, A.M.6
  • 14
    • 0029133207 scopus 로고
    • Kupffer cell-derived 95-kd type IV collagenase/gelatinase B: Characterisation and expression in cultured cells
    • 14. Winwood PJ, Schuppan D, Iredale JP, Kawser CA, Docherty AJP, Arthur MJP. Kupffer cell-derived 95-kd type IV collagenase/gelatinase B: characterisation and expression in cultured cells. Hepatology 1995; 22: 304-15.
    • (1995) Hepatology , vol.22 , pp. 304-315
    • Winwood, P.J.1    Schuppan, D.2    Iredale, J.P.3    Kawser, C.A.4    Docherty, A.J.P.5    Arthur, M.J.P.6
  • 15
    • 0016861504 scopus 로고
    • Cirrhosis in the alcoholic and its relation to the volume of alcohol abuse
    • 15. Lelbach WK. Cirrhosis in the alcoholic and its relation to the volume of alcohol abuse. Ann NY Acad Sci 1975; 252: 85-105.
    • (1975) Ann NY Acad Sci , vol.252 , pp. 85-105
    • Lelbach, W.K.1
  • 16
    • 3042995161 scopus 로고
    • Sequential production of fatty liver, hepatitis, and cirrhosis in sub-human primates fed ethanol with adequate diets
    • 16. Lieber CS, DeCarli L, Rubin E. Sequential production of fatty liver, hepatitis, and cirrhosis in sub-human primates fed ethanol with adequate diets. Proc Natl Acad Sci USA 1975; 72: 437-41.
    • (1975) Proc Natl Acad Sci USA , vol.72 , pp. 437-441
    • Lieber, C.S.1    DeCarli, L.2    Rubin, E.3
  • 18
    • 0023183834 scopus 로고
    • Long-term histological evaluation of the natural history and prognostic factors of alcoholic liver disease
    • 18. Marbet UA, Bianchi L, Meury U. Stalder GA. Long-term histological evaluation of the natural history and prognostic factors of alcoholic liver disease. J Hepatol 1987; 4: 364-72.
    • (1987) J Hepatol , vol.4 , pp. 364-372
    • Marbet, U.A.1    Bianchi, L.2    Meury, U.3    Stalder, G.A.4
  • 19
    • 0015450369 scopus 로고
    • Natural history of alcoholic hepatitis: 3. Histological changes
    • 19. Galambos JT. Natural history of alcoholic hepatitis: 3. Histological changes. Gastroenterology 1972; 63: 1026-35.
    • (1972) Gastroenterology , vol.63 , pp. 1026-1035
    • Galambos, J.T.1
  • 20
    • 0023025701 scopus 로고
    • Histologic spectrum of alcoholic liver disease
    • 20. MacSween RN, Burt AD. Histologic spectrum of alcoholic liver disease. [Review]. Semin Liver Dis 1986; 6: 221-32.
    • (1986) Semin Liver Dis , vol.6 , pp. 221-232
    • MacSween, R.N.1    Burt, A.D.2
  • 21
    • 0017669093 scopus 로고
    • Early perivenular sclerosis in alcoholic fatty liver: An index of progressive liver injury
    • 21. Van Waes L, Lieber CS. Early perivenular sclerosis in alcoholic fatty liver: an index of progressive liver injury. Gastroenterology 1977; 73: 646-50.
    • (1977) Gastroenterology , vol.73 , pp. 646-650
    • Van Waes, L.1    Lieber, C.S.2
  • 22
    • 0019945491 scopus 로고
    • Perivenular fibrosis in alcoholic liver injury: Ultrastructure and histologic progression
    • 22. Nakano M, Worner TM, Lieber CS. Perivenular fibrosis in alcoholic liver injury: ultrastructure and histologic progression. Gastroenterology 1982; 83: 777-85.
    • (1982) Gastroenterology , vol.83 , pp. 777-785
    • Nakano, M.1    Worner, T.M.2    Lieber, C.S.3
  • 23
    • 0025752432 scopus 로고
    • Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism
    • 23. Casini A, Cunningham M, Rojkind M, Lieber CS. Acetaldehyde increases procollagen type I and fibronectin gene transcription in cultured rat fat-storing cells through a protein synthesis-dependent mechanism. Hepatology 1991; 13: 758-65.
    • (1991) Hepatology , vol.13 , pp. 758-765
    • Casini, A.1    Cunningham, M.2    Rojkind, M.3    Lieber, C.S.4
  • 24
    • 0025847352 scopus 로고
    • Regulation of collagen production in freshly isolated cell populations from normal and cirrhotic rat liver: Effect of lactate
    • 24. Cerbon-Ambriz J, Cerbon-Solorzano J, Rojkind M. Regulation of collagen production in freshly isolated cell populations from normal and cirrhotic rat liver: effect of lactate. Hepatology 1991; 13: 551-6.
    • (1991) Hepatology , vol.13 , pp. 551-556
    • Cerbon-Ambriz, J.1    Cerbon-Solorzano, J.2    Rojkind, M.3
  • 25
    • 0027226140 scopus 로고
    • Stimulation of lipid peroxidation or 4hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells
    • 25. Parola M, Pinzani M, Casini A, Albano E, Poli G, Gentilini A, Gentilini P, Dianzani MU. Stimulation of lipid peroxidation or 4hydroxynonenal treatment increases procollagen alpha 1 (I) gene expression in human liver fat-storing cells. Biochem Biophys Res Commun 1993; 194: 1044-50.
    • (1993) Biochem Biophys Res Commun , vol.194 , pp. 1044-1050
    • Parola, M.1    Pinzani, M.2    Casini, A.3    Albano, E.4    Poli, G.5    Gentilini, A.6    Gentilini, P.7    Dianzani, M.U.8
  • 26
    • 0021173477 scopus 로고
    • Prospective evaluation of alcohol abuse and alcoholic liver injury in men as predictors of development of cirrhosis
    • 26. Sorensen TI, Orholm M, Bentsen KD, Hoybye G. Eghoje K, Christoffersen P. Prospective evaluation of alcohol abuse and alcoholic liver injury in men as predictors of development of cirrhosis. Lancet 1984; 2: 241-4.
    • (1984) Lancet , vol.2 , pp. 241-244
    • Sorensen, T.I.1    Orholm, M.2    Bentsen, K.D.3    Hoybye, G.4    Eghoje, K.5    Christoffersen, P.6
  • 27
    • 0029165057 scopus 로고
    • Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver
    • 27. Teli MR, Day CP, Burt AD, Bennet MK, James OFW. Determinants of progression to cirrhosis or fibrosis in pure alcoholic fatty liver. Lancet 1995; 346: 987-90.
    • (1995) Lancet , vol.346 , pp. 987-990
    • Teli, M.R.1    Day, C.P.2    Burt, A.D.3    Bennet, M.K.4    James, O.F.W.5
  • 31
    • 0021276139 scopus 로고
    • Alcoholic liver injury in baboons: Transformation of lipocytes to transitional cells
    • 31. Mak KM, Leo MA, Lieber CS. Alcoholic liver injury in baboons: transformation of lipocytes to transitional cells. Gastroenterology 1984; 87: 188-200.
    • (1984) Gastroenterology , vol.87 , pp. 188-200
    • Mak, K.M.1    Leo, Ma.2    Lieber, C.S.3
  • 32
    • 0020562702 scopus 로고
    • The role of the Ito cell in perivenular and intralobular fibrosis in alcoholic hepatitis
    • 32. Okanoue T, Burbige EJ, French SW The role of the Ito cell in perivenular and intralobular fibrosis in alcoholic hepatitis. Arch Pathol Lab Med 1983; 107: 459-63.
    • (1983) Arch Pathol Lab Med , vol.107 , pp. 459-463
    • Okanoue, T.1    Burbige, E.J.2    French, S.W.3
  • 33
    • 0022899793 scopus 로고
    • Early alcoholic liver injury. Activation of lipocytes in acinar zone 3 and correlation to degree of collagen formation in the Disse space
    • 33. Horn T, Junge J, Christoffersen P. Early alcoholic liver injury. Activation of lipocytes in acinar zone 3 and correlation to degree of collagen formation in the Disse space. J Hepatol 1986; 3: 333-40.
    • (1986) J Hepatol , vol.3 , pp. 333-340
    • Horn, T.1    Junge, J.2    Christoffersen, P.3
  • 34
    • 0023772719 scopus 로고
    • Lipocytes and transitional cells in alcoholic liver disease: A morphometric study
    • 34. Mak KM, Lieber CS. Lipocytes and transitional cells in alcoholic liver disease: a morphometric study. Hepatology 1988; 8: 1027-33.
    • (1988) Hepatology , vol.8 , pp. 1027-1033
    • Mak, K.M.1    Lieber, C.S.2
  • 35
    • 0025485813 scopus 로고
    • Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes
    • 35. Moshage H, Casini A, Lieber CS. Acetaldehyde selectively stimulates collagen production in cultured rat liver fat-storing cells but not in hepatocytes. Hepatology 1990; 12: 511-8.
    • (1990) Hepatology , vol.12 , pp. 511-518
    • Moshage, H.1    Casini, A.2    Lieber, C.S.3
  • 36
    • 0027730075 scopus 로고
    • Acetaldehyde-protein adducts, but not lactate and pyruvate, stimulate gene transcription of collagen and fibronectin in hepatic fat-storing cells
    • 36. Casini A, Galli G, Salzano R, Rotella CM, Surrenti C. Acetaldehyde-protein adducts, but not lactate and pyruvate, stimulate gene transcription of collagen and fibronectin in hepatic fat-storing cells. J Hepatol 1993; 19: 385-92.
    • (1993) J Hepatol , vol.19 , pp. 385-392
    • Casini, A.1    Galli, G.2    Salzano, R.3    Rotella, C.M.4    Surrenti, C.5
  • 37
    • 0021674138 scopus 로고
    • Relationship of oxygen and glutathione in protection against carbon tetrachloride-induced hepatic microsomal lipid peroxidation and covalent binding in the rat. Rationale for the use of hyperbaric oxygen to treat carbon tetrachloride ingestion
    • 37. Burk RF, Lane JM, Patel K. Relationship of oxygen and glutathione in protection against carbon tetrachloride-induced hepatic microsomal lipid peroxidation and covalent binding in the rat. Rationale for the use of hyperbaric oxygen to treat carbon tetrachloride ingestion. J Clin Invest 1984; 74: 1996-2001.
    • (1984) J Clin Invest , vol.74 , pp. 1996-2001
    • Burk, R.F.1    Lane, J.M.2    Patel, K.3
  • 39
    • 0024823493 scopus 로고
    • Role of lipid peroxidation and oxidative stress in alcohol toxicity
    • 39. Cederbaum AI. Role of lipid peroxidation and oxidative stress in alcohol toxicity. Free Rad Biol Med 1989; 7: 537-9.
    • (1989) Free Rad Biol Med , vol.7 , pp. 537-539
    • Cederbaum, A.I.1
  • 41
    • 0018888158 scopus 로고
    • Copper and the liver
    • 41. Sternlieb I. Copper and the liver. Gastroenterology 1980; 78: 1615-28.
    • (1980) Gastroenterology , vol.78 , pp. 1615-1628
    • Sternlieb, I.1
  • 42
    • 0028795316 scopus 로고
    • Liver cell necrosis: Cellular mechanisms and clinical implications
    • 42. Rosser BG, Gores GJ. Liver cell necrosis: cellular mechanisms and clinical implications. Gastroenterology 1995; 108: 252-75.
    • (1995) Gastroenterology , vol.108 , pp. 252-275
    • Rosser, B.G.1    Gores, G.J.2
  • 43
    • 0021326099 scopus 로고
    • Content of hepatic reduced glutathione in chronic alcoholic patients: Influence of the length of abstinence and liver necrosis
    • 43. Videla LA, Iturriaga H, Pino ME, Bunout D, Valenzuela A, Ugarte G. Content of hepatic reduced glutathione in chronic alcoholic patients: influence of the length of abstinence and liver necrosis. Clin Sci 1984; 66: 283-90.
    • (1984) Clin Sci , vol.66 , pp. 283-290
    • Videla, L.A.1    Iturriaga, H.2    Pino, M.E.3    Bunout, D.4    Valenzuela, A.5    Ugarte, G.6
  • 44
    • 0023786779 scopus 로고
    • Hepatic glutathione content in patients with alcoholic and non-alcoholic liver diseases
    • 44. Altomare E, Vendemiale G, Albano O. Hepatic glutathione content in patients with alcoholic and non-alcoholic liver diseases. Life Sci 1988; 43: 991-8.
    • (1988) Life Sci , vol.43 , pp. 991-998
    • Altomare, E.1    Vendemiale, G.2    Albano, O.3
  • 46
    • 4244163145 scopus 로고
    • Lipid peroxidation-induced isoprostane independently activates ito cell MAP kinase and increases type I collagen mRNA abundance
    • 46. Beno DWA, Retsky JE, Davis BH. Lipid peroxidation-induced isoprostane independently activates ito cell MAP kinase and increases type I collagen mRNA abundance. Hepatology 1994; 20: 291A.
    • (1994) Hepatology , vol.20
    • Beno, D.W.A.1    Retsky, J.E.2    Davis, B.H.3
  • 47
    • 4244051434 scopus 로고
    • Acetaldehyde, malondialdehyde, and 4-hydroxynonenal adducts and ito cell activation in iron potentiated alcoholic liver fibrosis
    • 47. Tsukamoto H, Niemela O, Parkkila S, Yla-Herttuala S, Brittenham G. Acetaldehyde, malondialdehyde, and 4-hydroxynonenal adducts and ito cell activation in iron potentiated alcoholic liver fibrosis. Hepatology 1994; 20: 314A.
    • (1994) Hepatology , vol.20
    • Tsukamoto, H.1    Niemela, O.2    Parkkila, S.3    Yla-Herttuala, S.4    Brittenham, G.5
  • 48
    • 0028181393 scopus 로고
    • Stimulation of collagen alpha 1(I) gene expression is associated with lipid peroxidation in hepatocellular injury: A link to tissue fibrosis?
    • 48. Bedossa P, Houglum K, Trautwein C, Holstege A, Chojkier M. Stimulation of collagen alpha 1(I) gene expression is associated with lipid peroxidation in hepatocellular injury: a link to tissue fibrosis? Hepatology 1994; 19: 1262-71.
    • (1994) Hepatology , vol.19 , pp. 1262-1271
    • Bedossa, P.1    Houglum, K.2    Trautwein, C.3    Holstege, A.4    Chojkier, M.5
  • 49
    • 0028134772 scopus 로고
    • The biochemistry of alcohol-induced fatty liver
    • 49. Day CP, Yeaman SJ. The biochemistry of alcohol-induced fatty liver. Biochim Biophys Acta 1994; 1215: 33-48.
    • (1994) Biochim Biophys Acta , vol.1215 , pp. 33-48
    • Day, C.P.1    Yeaman, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.