Protein phosphatase 2A is a negative regulator of IL-2 production in patients with systemic lupus erythematosus

Journal of Clinical Investigation

Volumn 115, Issue 11, 2005, Pages 3193-3204

  Katsiari, Christina G ^a   Kyttaris, Vasileios C ^a,b,c   Juang, Yuang Taung ^a,b   Tsokos, George C ^a,b  

^a WALTER REED ARMY INSTITUTE OF RESEARCH   (United States)

^b Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^c WASHINGTON HOSPITAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; BETA ACTIN; CALCIMYCIN; CELL PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLOPHOSPHAMIDE; HYDROXYCHLOROQUINE; INTERLEUKIN 2; MESSENGER RNA; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; PHORBOL 13 ACETATE 12 MYRISTATE; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2A; PREDNISONE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE ACTIVITY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GEL MOBILITY SHIFT ASSAY; HUMAN; HUMAN CELL; IMMUNOPATHOLOGY; ONCOGENE C FOS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYSTEMIC LUPUS ERYTHEMATOSUS; T LYMPHOCYTE ACTIVATION; WESTERN BLOTTING;

ADULT; AGED; AGED, 80 AND OVER; CATALYTIC DOMAIN; CELLS, CULTURED; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DOWN-REGULATION; FEMALE; HUMANS; IMMUNOGLOBULIN G; INTERLEUKIN-2; LUPUS ERYTHEMATOSUS, SYSTEMIC; MIDDLE AGED; PHOSPHOPROTEIN PHOSPHATASE; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-FOS; RNA, MESSENGER; RNA, SMALL INTERFERING; T-LYMPHOCYTE SUBSETS; TRANSCRIPTION FACTOR AP-1; UP-REGULATION;

EID: 27644546349     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI24895     Document Type: Article

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