Recruitment of CBP/p300 by the IFNβ enhanceosome is required for synergistic activation of transcription

Molecular Cell

Volumn 1, Issue 2, 1998, Pages 277-287

  Merika, Menie ^a   Williams, Amy J ^b   Chen, Guoying ^a   Collins, Tucker ^b   Thanos, Dimitris ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; BETA INTERFERON; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; DNA BINDING PROTEIN; HISTONE ACETYLTRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; LEUCINE ZIPPER PROTEIN; NUCLEAR PROTEIN; NUCLEAR RECEPTOR COACTIVATOR 3; PHOSPHOPROTEIN; PROTEIN C JUN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR RELA;

ANIMAL; ARTICLE; BINDING SITE; CELL STRAIN COS1; CHEMISTRY; ENHANCER REGION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; TRANSACTIVATION;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; BINDING SITES; COS CELLS; CREB-BINDING PROTEIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA-BINDING PROTEINS; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION, VIRAL; HISTONE ACETYLTRANSFERASES; INTERFERON REGULATORY FACTOR-1; INTERFERON-BETA; LEUCINE ZIPPERS; NF-KAPPA B; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; PROTO-ONCOGENE PROTEINS C-JUN; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTORS; TRANSFECTION;

EID: 0031604766     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80028-3     Document Type: Article

References (39)

1. Bannister, A.J., Oehler, T., Wilhelm, D., Angel, P., and Kouzarides, T. (1995). Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitro. Oncogene 11, 2509-2514.
2. Bannister, A.J., and Kouzarides, T. (1996). The CBP co-activator is a histone acetyltransferase. Nature 384, 641-643.
3. Bhattacharya, S., Eckner, R., Grossman, S., Oldread, E., Arany, Z., D'Andrea, A., and Livingston, D.M. (1996). Cooperation of Stat2 and p300/CBP in signaling induced by interferon-α. Nature 383, 344-347.
4. Du, W., Thanos, D., and Maniatis, T. (1993). Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements. Cell 74, 887-898.
5. Eckner, R., Ewen, M., Newsome, D., Gerdes, M., DeCaprio, J., Lawrence, J., and Livingston, D. (1994). Molecular cloning and functional analysis of the adenovirus E1A associated 300-KD (p300) reveals a protein with properties of a transcriptional adaptor. Genes Dev. 8, 869-884.
6. Falvo, J.V., Thanos, D., and Maniatis, T. (1995). Reversal of intrinsic DNA bends in the IFNβ gene enhancer by transcription factors and the architectural protein HMG I(Y). Cell 83, 1101-1111.
7. Gerritsen, M.E., Williams, A.J., Neish, A.S., Moore, S., Shi, Y., and Collins, T. (1997). CREB binding protein/p300 are transcriptional coactivators of p65. Proc. Natl. Acad. Sci. USA 94, 2927-2932.
8. Giese, K., and Grosschedl R. (1993). LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor binding sites. EMBO J. 12, 4667-4676.
9. Guarente L. (1995). Transcriptional coactivators in yeast and beyond. Trends Biochem. Sci. 20, 517-521.
10. Halle, J.-P., and Meisternest, M. (1996). Gene expression: increasing evidence for a transcriptosome. Trends Genet. 12, 161-163.
11. Harada, H., Fujita, T., Miyamoto, M., Kimura, Y., Maruyama, M., Furia, A., Miyata, T., and Taniguchi, T. (1989). Structurally similar but functionally distinct factors, IRF1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 58, 729-739.
12. Heery, D.M., Kalkhoven, E., Hoare, S., and Parker, M.G. (1997). A signature motif in transcriptional co-activators mediates binding to nuclear receptors. Nature 387, 733-736.
13. Hill, C.S., and Treisman, R. (1995). Transcriptional regulation by extracellular signals: mechanisms and specificity. Cell 80, 199-211.
14. Holloway, J.M., Szeto, D.P. ,Scully, K.M., Glass, C.K., and Rosenfeld, M.G. (1995). Pit-1 binding to specific DNA sites as a monomer or dimer determines gene-specific use of a tyrosine-dependent synergy domain. Genes Dev. 9, 1992-2006.
15. Janknecht, R., and Hunter, T. (1996). Transcriptional control: versatile molecular glue. Curr. Biol. 6, 951-954.
16. Kaiser, K., and Meisternest, M. (1996). The human general co-factors. Trends Biochem. Sci. 21, 342-345.
17. Kee, B.L., Arias, J., and Montminy, M.R. (1996). Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator. J. Biol. Chem. 271, 2373-2375.
18. Kim, T.K., and Maniatis, T. (1997). The mechanism of transcriptional synergy of an in vitro assembled interferon-β enhanceosome. Mol. Cell 1, 119-129.
19. Kwok, R.P.S., Lundbland, J.R., Chrivia, J.C., Richards, J.P., Bachinger, H.P., Brennan, R.G., Roberts, S.G.E., Green, M.R., and Goodman, R.H. (1994). Nuclear protein CBP is a coactivator for the transcription factor CREB. Nature 370, 223-226.
20. Lee, J.-S., Galvin, K.M., See, R.H., Eckner, R., Livingston, D., Moran, E., and Shi, Y. (1995). Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300. Genes Dev. 9, 1188-1197.
21. Moore, P.A., Ruben, S.M., and Rosen, C.A. (1993). Conservation of transcriptional activation functions of the NF-κB p50 and p65 subunits in mammaliancells and Saccharomyces cerevisiae. Mol. Cell. Biol. 13, 1666-1674.
22. Nakajima, T., Uchida, C., Anderson, S.F., Parvin, J.D., and Montminy, M. (1997). Analysis of a cAMP-responsive activator reveals a two component mechanism for transcriptional induction via signal-dependent factors. Genes Dev. 11, 738-747.
23. Ogryzko, V.V., Schiltz, R.L., Russanova, V., Howard, B.H., and Nakatani, Y. (1996). The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 87, 953-959.
24. Perkins, N.D., Felzien, L.K., Betts, J.C., Leung, K., Beach, D.H., and Nabel, G.J. (1997). Regulation of NF-κB by cyclin-dependent kinases associated with the p300 coactivator. Science 275, 523-527.
25. Ptashne, M. (1992). A Genetic Switch, Second Edition (Cambridge, MA: Cell Press/Blackwell Scientific Publications).
26. Ptashne, M., and Gann, A. (1997). Transcriptional activation by recruitment. Nature 386, 569-577.
27. Roeder, R.G. (1996). The role of general initiation factors in transcription by RNA polymerase II. Trends Biochem. Sci. 21, 327-335.
28. Sauer, F., and Tjian, R. (1997). Mechanisms of transcriptional activation: differences and similarities between yeast, Drosophila and man. Curr. Opin. Genet. Dev. 7, 176-181.
29. Schmitz, M.L., and Baeuerle, P.A. (1991). The p65 subunit is responsible for the strong transcription activating potential of NF-κB. EMBO J. 10, 3805-3817.
30. Shikama, N., Lyon, J., and La Thangue, N.B. (1997). The p300/CBP family: integrating signals with transcription factors and chromatin. Trends Cell Biol. 7, 230-236.
31. Sun, P., and Maurer, R.A. (1995). An inactivating point mutation demonstrates that interaction of cAMP response element binding protein (CREB) with the CREB binding protein is not sufficient for transcriptional activation. J. Biol. Chem. 270, 7041-7044.
32. Thanos, D., and Maniatis, T. (1992).The high mobility group protein HMG I(Y) is required for NF-κB dependent virus induction of the human IFN-β gene. Cell 71, 777-789.
33. Thanos, D., Du, W., and Maniatis, T. (1993). The high mobility group protein HMG I(Y) is an essential structural component of a virus inducible enhancer complex. Cold Spring Harbor Symp. Quant. Biol. 58, 73-81.
34. Thanos, D., and Maniatis, T. (1995). Virus induction of human IFNβ gene expression requires the assembly of an enhanceosome. Cell 83, 1091-1100.
35. Tjian, R., and Maniatis, T. (1994). Transcriptional activation: a complex puzzle with few easy pieces. Cell 77, 5-8.
36. Torchia, J., Rose, D.W., Inostroza, J., Kamel, Y., Westin, S., Glass, C.K., and Rosenfeld, M.G. (1997). The transcriptional co-activator p/CIP binds CBP and mediates nuclear receptor function. Nature 387, 677-684.
37. Triezenberg, S.J. (1995). Structure and function of transcriptional activation domains. Curr. Opin. Genet. Dev. 5, 190-196.
38. Yie, J., Liang, S., Merika, M., and Thanos, D. (1997). Intra- and intermolecular cooperative binding of high mobility group protein I(Y) to the beta-interferon promoter. Mol. Cell Biol. 17, 3649-3662.
39. Yuan, W., Condorelli, G., Caruso, M., Felsani, A., and Giordano, A. (1996). Human p300 protein is a coactivator for the transcription factor MyoD. J. Biol. Chem. 277, 9009-9013.