Targeting of CD45 protein tyrosine phosphatase activity to lipid microdomains on the T cell surface inhibits TCR signaling

European Journal of Immunology

Volumn 32, Issue 9, 2002, Pages 2578-2587

  He, Xiao ^a,b   Woodford Thomas, Terry A ^a   Johnson, Kenneth G ^a   Shah, Dulari D ^a   Thomas, Matthew L ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b FOX CHASE CANCER CENTER   (United States)

^c DONALD DANFORTH PLANT SCIENCE CENTER   (United States)

Author keywords

CD45; Lipid microdomain; Protein tyrosine phosphatase; Signal transduction; TCR

Indexed keywords

AMINO ACID; CALCIUM ION; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; EGG WHITE; INTERLEUKIN 2; LYSOZYME; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CALCIUM MOBILIZATION; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CELL SURFACE; CHIMERA; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOPLASM; ENZYME ACTIVITY; GENE SEGREGATION; HYBRIDOMA; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN TARGETING; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ANIMALS; ANTIGENS, CD45; BINDING SITES; CALCIUM SIGNALING; CELL COMPARTMENTATION; CHICKENS; ENZYME ACTIVATION; HYBRIDOMAS; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE GLYCOPROTEINS; MEMBRANE MICRODOMAINS; MICE; MURAMIDASE; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; T-LYMPHOCYTES;

EID: 0036737124     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200209)32:9<2578::AID-IMMU2578>3.0.CO;2-3     Document Type: Article

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