Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells

European Journal of Immunology

Volumn 31, Issue 12, 2001, Pages 3649-3658

  Sathish, Jean G ^a   Johnson, Kenneth G ^a,c   LeRoy, Frances G ^a   Fuller, Kerensa J ^a,b   Hallett, Maurice B ^a   Brennan, Paul ^a   Borysiewicz, Leszek K ^a,d   Sims, Martin J ^b   Matthews, R James ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Costimulation; SHP 1; T cell receptor signaling

Indexed keywords

CALCIUM ION; CD28 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CELL ENZYME; INOSITOL TRISPHOSPHATE; INTERLEUKIN 2; PHOSPHOLIPASE C; PROTEIN TYROSINE PHOSPHATASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCHEMISTRY; CALCIUM CELL LEVEL; CONTROLLED STUDY; CYTOKINE PRODUCTION; LYMPHOCYTE DEPLETION; LYMPHOCYTE PROLIFERATION; MODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMOCYTE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; ANTIGENS, CD28; CALCIUM; CHROMONES; INOSITOL 1,4,5-TRISPHOSPHATE; INTERLEUKIN-2; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISOENZYMES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MORPHOLINES; PHOSPHOLIPASE C; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PROTEIN-TYROSINE-PHOSPHATASE; SHP1 PROTEIN TYROSINE PHOSPHATASE; T-LYMPHOCYTES; TYROSINE;

EID: 0035660611     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200112)31:12<3649::AID-IMMU3649>3.0.CO;2-8     Document Type: Article

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