Enlargement of secretory vesicles by protein tyrosine phosphatase PTP-MEG2 in rat basophilic leukemia mast cells and Jurkat T cells

Journal of Immunology

Volumn 168, Issue 9, 2002, Pages 4612-4619

  Wang, Xiaodong ^a   Huynh, Huong ^a   Gjörloff Wingren, Anette ^a   Monosov, Edvard ^a   Stridsberg, Mats ^a   Fukuda, Minoru ^a   Mustelin, Tomas ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMICAL MARKER; CARBOXYPEPTIDASE H; INTERLEUKIN 2; ISOENZYME; PERVANADATE; POLYPEPTIDE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE MEG2; SECRETOGRANIN II; SECRETORY PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; DEPHOSPHORYLATION; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME LOCALIZATION; GOLGI COMPLEX; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MAST CELL LEUKEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEIN TARGETING; PROTEIN TRANSPORT; RAT; SECRETORY VESICLE;

EID: 0036570013     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.9.4612     Document Type: Article

References (36)

1. Oncogenes and signal transduction
2. Protein kinases and phosphatases: The yin and yang of protein phosphorylation and signaling
3. lck
4. + thymic selection in humans lacking Zap-70 kinase
5. Molecular basis of human B cell neoplasia
6. Chromosomal translocations joining LCK and TCRB loci in human T cell leukemia
7. TCR diminished signaling in cutaneous T-cell lymphoma is associated with decreased kinase activities of Syk and membrane-associated Csk
8. From form to function: Signaling by protein tyrosine phosphatases
9. T cell activation: The coming of the phosphatases
10. Cloning and expression of a cytosolic megalkaryocyte protein-tyrosine-phosphatase with sequence homology to retinaldehyde-binding protein and yeast SEC14p
11. Characterization of two structurally related Xenopus laevis protein tyrosine phosphatases with homology to lipid-binding proteins
12. Primary structure of α-tocopherol transfer protein from rat liver: Homology with cellular retinaldehyde-binding protein
13. A novel 45 kDa secretory protein from rat olfactory epithelium: Primary structure and localisation
14. Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3′ untranslated region
15. Sec14p-like domains in NF1 and Dbl-like proteins indicate lipid regulation of Ras and Rho signaling
16. Subcellular localization of intracellular protein tyrosine phosphatases in T cells
17. Phorbol ester-resistant monoblastoid leukemia cells with a functional mitogen-activated protein kinase cascade but without responsive protein tyrosine phosphatases
18. Isolation and characterization of human lysosomal membrane glycoproteins, h-lamp-1 and h-lamp-2
19. Molecular cloning and expression of a novel human trans-Golgi network glycoprotein, TGN51, that contains multiple tyrosine-containing motifs
20. Measurement of chromogranin A, chromogranin B (secretogranin 1), chromogranin C (secretogranin 11) and pancreastatin in plasma and urine of patients with carcinoid tumours
21. Negative regulation of T cell antigen receptor signaling by hematopoietic tyrosine phosphatase (HePTP)
22. Inhibition of phosphatidylinositol 3-kinase blocks TCR/CD3-induced activation of the mitogen-activated kinase Erk2
23. Regulation of the Lck SH2 domain by tyrosine phosphorylation
24. Involvement of phosphatidylinositol 3-kinase in NFAT activation in T cells
25. Inhibition of T cell signaling by MAP kinase-targeted hematopoietic tyrosine phosphatase (HePTP)
26. Crosstalk between cAMP-dependent kinase and MAP kinase through hematopoietic protein tyrosine phosphatase (HePTP)
27. Nyk by TCR/CD3 stimulation
28. The use of lead citrate at high pH as an electronopaque stain in electron microscopy
29. Carboxypeptidase E is a regulated secretory pathway sorting receptor: Genetic obliteration leads to endocrine disorders in Cpe(fat) mice
30. Human carboxypeptidase E: Isolation and characterization of the cDNA, sequence conservation, expression and processing in vitro
31. Hyperproinsulinaemia in obese fat/fat mice associated with a carboxypeptidase E mutation which reduces enzyme activity
32. Regulated secretion from hematopoietic cells
33. Crystal structure of human protein tyrosine phosphatase 1B
34. Formation of the insulin-containing secretory granule core occurs within immature β-granules
35. Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors