Stimulation of human natural interferon-α response via paramyxovirus hemagglutinin lectin-cell interaction

Journal of Molecular Medicine

Volumn 80, Issue 7, 2002, Pages 443-451

  Zeng, Jinyang ^a   Fournier, Philippe ^a   Schirrmacher, Volker ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Cell binding and hemadsorption; Hemagglutinin neuraminidase; Innate immunity; Interferon ; Newcastle disease virus

Indexed keywords

ALPHA INTERFERON; CELL RECEPTOR; DNA; HEMAGGLUTININ; HN PROTEIN; LECTIN; MUTANT PROTEIN; SIALIC ACID; SIALIDASE; CELL SURFACE RECEPTOR; SIALIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; CELL DAMAGE; CELL INTERACTION; CELL STRAIN BHK; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA TRANSFECTION; ENZYME ACTIVITY; ENZYME ASSAY; HEMADSORPTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOSTIMULATION; MOLECULAR MECHANICS; MOLECULAR RECOGNITION; MONONUCLEAR CELL; NEWCASTLE DISEASE PARAMYXOVIRUS; NONHUMAN; PARAMYXOVIRUS; PROTEIN EXPRESSION; ULTRAVIOLET IRRADIATION; VIRUS ENVELOPE; VIRUS IMMUNITY; ADSORPTION; ANIMAL; CELL LINE; CHEMISTRY; FLOW CYTOMETRY; GENETICS; HAMSTER; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE; SITE DIRECTED MUTAGENESIS; ULTRAVIOLET RADIATION;

ADSORPTION; ANIMAL; CELL LINE; FLOW CYTOMETRY; HAMSTERS; HN PROTEIN; HUMAN; IMMUNITY, NATURAL; INTERFERON-ALPHA; LEUKOCYTES, MONONUCLEAR; MUTAGENESIS, SITE-DIRECTED; NEWCASTLE DISEASE VIRUS; RECEPTORS, CELL SURFACE; RESPIROVIRUS; SIALIC ACIDS; ULTRAVIOLET RAYS; ANIMALS; CRICETINAE; HUMANS;

EID: 0036019520     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00109-002-0339-1     Document Type: Article

References (35)

1. Antiviral actions of interferons
2. Interferons: Cell signalling, immune modulation, antiviral response and virus countermeasures
3. Tumor immunity after viral oncolysis
4. Scientific interest in Newcastle disease virus is reviving
5. Tumor cell number and viability as quality and efficacy parameters of autologous virus modified cancer vaccines
6. Immunization with virus-modified tumor cells
7. Human tumor cell modification by virus infection: An efficient and safe way to produce cancer vaccine with pleiotropic immune stimulatory properties when using Newcastle disease virus
8. Tumor vaccines - New therapeutic approaches against cancer
9. Double-stranded RNA activates novel factors that bind to the interferon-stimulated response element
10. Characterization of specific DNA-binding factors activated by double-stranded RNA as positive regulators of interferon alpha/beta-stimulated genes
11. Interferon regulatory factor 3 and CREB-binding protein/p300 are subunits of double-stranded RNA-activated transcription factor DRAF1
12. Induction of interferon-α and tumor necrosis factor - Related apoptosis inducing ligand (TRAIL) in human blood mononuclear cells by HN but not F protein of Newcastle disease virus
13. Crystallization of Newcastle disease virus hemagglutinin-neuraminidase glycoprotein
14. Crystal structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase
15. Site-directed mutagenesis of a conserved hexapeptide in the paramyxovirus hemagglutinin-neuraminidase glycoprotein: Effects on antigenic structure and function
16. Structure and function of a membrane anchor-less form of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus
17. Isolation and purification of the envelope proteins of Newcastle disease virus
18. Sequence and structure alignment of paramyxovirus hemagglutinin-neuraminidase with influenza virus neuraminidase
19. Functional and neutralization profile of seven overlapping antigenic sites on the HN glycoprotein of Newcastle disease virus: Monoclonal antibodies to some sites prevent viral attachment
20. Virus potentiation of tumor vaccine T-cell stimulatory capacity requires cell surface binding but not infection
21. Signal transduction pathway activating interferon-alpha-stimulated gene expression
22. Paramyxovirus reverse genetics is coming of age
23. Nucleotide sequence of the gene Newcastle disease virus hemagglutinin-neuraminidase protein and comparisons of paramyxovirus hemagglutinin-neuraminidase protein sequences
24. Neutralization map of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus: Domains recognized by monoclonal antibodies that prevent receptor recognition
25. Identification of amino acid residues important to the neuraminidase activity of the HN glycoprotein of Newcastle disease virus
26. Structural and functional relationship between the receptor recognition and neuraminidase activities of the Newcastle disease virus hemagglutinin-neuraminidase protein: Receptor recognition is dependent on neuraminidase activity
27. Amino acid substitutions in a conserved region in the stalk of the Newcastle disease virus HN glycoprotein spike impair its neuraminidase activity in the globular domain
28. Mutations in the NDV hemagglutinin-neuraminidase protein that interfere with its ability to interact with the homologous F protein in the promotion of fusion
29. A single amino acid substitution in the hemagglutinin-neuraminidase of Newcastle disease virus results in a protein deficient in both functions
30. The cell surface phenotype of human natural interferon-alpha producing cells as determined by flow cytometry
31. The nature of the principal type 1 interferon-producing cells in human blood
32. Natural interferon alpha-beta have innate and adaptative immunity
33. Aberrant membrane insertion of a cytoplasmic tail deletion mutant of the hemagglutinin-neuraminidase glycoprotein of Newcastle disease virus
34. Gangliosides as paramyxovirus receptor. Structural requirement of sialo-oligosaccharides in receptors for hemagglutinating virus of Japan (Sendai virus) and Newcastle disease virus
35. Recognition of double-stranded RNA and activation of NF-kκB by Toll-like receptor 3