메뉴 건너뛰기




Volumn 175, Issue 7, 2005, Pages 4465-4474

Analyzing expression of perforin, Runx3, and Thpok genes during positive selection reveals activation of CD8-differentiation programs by MHC II-signaled thymocytes

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; PERFORIN; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR RUNX3;

EID: 25444465125     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.175.7.4465     Document Type: Article
Times cited : (29)

References (64)
  • 1
    • 0036582215 scopus 로고    scopus 로고
    • T-cell development and the CD4-CD8 lineage decision
    • Germain, R. N. 2002. T-cell development and the CD4-CD8 lineage decision. Nat. Rev. Immunol. 2: 309-322.
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 309-322
    • Germain, R.N.1
  • 2
    • 2442708080 scopus 로고    scopus 로고
    • CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: Analysis of the CD4/CD8 lineage decision
    • Singer, A., and R. Bosselut. 2004. CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision. Adv. Immunol. 83: 91-131.
    • (2004) Adv. Immunol. , vol.83 , pp. 91-131
    • Singer, A.1    Bosselut, R.2
  • 3
    • 3142769748 scopus 로고    scopus 로고
    • CD4/CD8 lineage differentiation in the thymus: From nuclear effectors to membrane signals
    • Bosselut, R. 2004. CD4/CD8 lineage differentiation in the thymus: from nuclear effectors to membrane signals. Nat. Rev. Immunol. 4: 529-540.
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 529-540
    • Bosselut, R.1
  • 5
    • 0033565424 scopus 로고    scopus 로고
    • Activation of the extracellular signal-related kinase/mitogen-activated protein kinase pathway discriminates CD4 versus CD8 lineage, commitment in the thymus
    • Bommhardt, U., M. A. Basson, U. Krummrei, and R. Zamoyska. 1999. Activation of the extracellular signal-related kinase/mitogen-activated protein kinase pathway discriminates CD4 versus CD8 lineage, commitment in the thymus. J. Immunol. 163: 715-722.
    • (1999) J. Immunol. , vol.163 , pp. 715-722
    • Bommhardt, U.1    Basson, M.A.2    Krummrei, U.3    Zamoyska, R.4
  • 6
    • 18744398397 scopus 로고    scopus 로고
    • Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development
    • Taniuchi, I., M. Osato, T. Egawa, M. J. Sunshine, S. C. Bae, T. Komori, Y. Ito, and D. R. Littman. 2002. Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development. Cell 111: 621-633.
    • (2002) Cell , vol.111 , pp. 621-633
    • Taniuchi, I.1    Osato, M.2    Egawa, T.3    Sunshine, M.J.4    Bae, S.C.5    Komori, T.6    Ito, Y.7    Littman, D.R.8
  • 7
    • 0038783583 scopus 로고    scopus 로고
    • GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation
    • Hernandez-Hoyos, G., M. K. Anderson, C. Wang, E. V. Rothenberg, and J. Alberola-Ila. 2003. GATA-3 expression is controlled by TCR signals and regulates CD4/CD8 differentiation. Immunity 19: 83-94.
    • (2003) Immunity , vol.19 , pp. 83-94
    • Hernandez-Hoyos, G.1    Anderson, M.K.2    Wang, C.3    Rothenberg, E.V.4    Alberola-Ila, J.5
  • 8
    • 0348110327 scopus 로고    scopus 로고
    • Critical roles for transcription factor GATA-3 in thymocyte development
    • Pai, S. Y., M. L. Truitt, C. Ting, J. M. Leiden, L. H. Glimcher, and I. C. Ho. 2003. Critical roles for transcription factor GATA-3 in thymocyte development. Immunity 19: 863-875.
    • (2003) Immunity , vol.19 , pp. 863-875
    • Pai, S.Y.1    Truitt, M.L.2    Ting, C.3    Leiden, J.M.4    Glimcher, L.H.5    Ho, I.C.6
  • 10
    • 14544288635 scopus 로고    scopus 로고
    • The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment
    • He, X., X. He, V. P. Dave, Y. Zhang, X. Hua, E. Nicolas, W. Xu, B. A. Roe, and D. J. Kappes. 2005. The zinc finger transcription factor Th-POK regulates CD4 versus CD8 T-cell lineage commitment. Nature 433: 826-833.
    • (2005) Nature , vol.433 , pp. 826-833
    • He, X.1    He, X.2    Dave, V.P.3    Zhang, Y.4    Hua, X.5    Nicolas, E.6    Xu, W.7    Roe, B.A.8    Kappes, D.J.9
  • 11
    • 16844375768 scopus 로고    scopus 로고
    • The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection
    • Sun, G., X. Liu, P. Mercado, S. R. Jenkinson, M. Kypriotou, L. Feigenbaum, P. Galera, and R. Bosselut. 2005. The zinc finger protein cKrox directs CD4 lineage differentiation during intrathymic T cell positive selection. Nat. Immunol. 6: 373-381.
    • (2005) Nat. Immunol. , vol.6 , pp. 373-381
    • Sun, G.1    Liu, X.2    Mercado, P.3    Jenkinson, S.R.4    Kypriotou, M.5    Feigenbaum, L.6    Galera, P.7    Bosselut, R.8
  • 12
    • 0030002882 scopus 로고    scopus 로고
    • The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells
    • Itano, A., P. Salmon, D. Kioussis, M. Tolaini, P. Corbella, and E. Robey. 1996. The cytoplasmic domain of CD4 promotes the development of CD4 lineage T cells. J. Exp. Med. 183: 731-741.
    • (1996) J. Exp. Med. , vol.183 , pp. 731-741
    • Itano, A.1    Salmon, P.2    Kioussis, D.3    Tolaini, M.4    Corbella, P.5    Robey, E.6
  • 13
    • 0029988961 scopus 로고    scopus 로고
    • MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent
    • Matechak, E. O., N. Killeen, S. M. Hedrick, and B. J. Fowlkes. 1996. MHC class II-specific T cells can develop in the CD8 lineage when CD4 is absent. Immunity 4: 337-347.
    • (1996) Immunity , vol.4 , pp. 337-347
    • Matechak, E.O.1    Killeen, N.2    Hedrick, S.M.3    Fowlkes, B.J.4
  • 14
    • 0030989595 scopus 로고    scopus 로고
    • Signals through CD8 or CD4 can induce commitment to the CD4 lineage in the thymus
    • Bommhardt, U., M. S. Cole, J. Y. Tso, and R. Zamoyska. 1997. Signals through CD8 or CD4 can induce commitment to the CD4 lineage in the thymus. Eur. J. Immunol, 27: 1152-1163.
    • (1997) Eur. J. Immunol , vol.27 , pp. 1152-1163
    • Bommhardt, U.1    Cole, M.S.2    Tso, J.Y.3    Zamoyska, R.4
  • 18
    • 1542377327 scopus 로고    scopus 로고
    • Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo
    • Liu, X., and R. Bosselut. 2004. Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo. Nat. Immunol. 5: 280-288.
    • (2004) Nat. Immunol. , vol.5 , pp. 280-288
    • Liu, X.1    Bosselut, R.2
  • 19
    • 0027266755 scopus 로고
    • Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes
    • Davis, C. B., N. Killeen, M. E. Crooks, D. Raulet, and D. R. Littman. 1993. Evidence for a stochastic mechanism in the differentiation of mature subsets of T lymphocytes. Cell 73: 237-247.
    • (1993) Cell , vol.73 , pp. 237-247
    • Davis, C.B.1    Killeen, N.2    Crooks, M.E.3    Raulet, D.4    Littman, D.R.5
  • 21
    • 0028075391 scopus 로고
    • Role of coreceptors in positive selection and lineage commitment
    • Chan, S. H., C. Waltzinger, A. Baron, C. Benoist, and D. Mathis. 1994. Role of coreceptors in positive selection and lineage commitment. EMBO J. 13: 4482-4489.
    • (1994) EMBO J. , vol.13 , pp. 4482-4489
    • Chan, S.H.1    Waltzinger, C.2    Baron, A.3    Benoist, C.4    Mathis, D.5
  • 22
    • 0028053092 scopus 로고
    • Stochastic component to development of class I major histocompatibility complex-specific T cells
    • Itano, A., D. Kioussis, and E. Robey. 1994. Stochastic component to development of class I major histocompatibility complex-specific T cells. Proc. Natl. Acad. Sci. USA 91: 220-224.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 220-224
    • Itano, A.1    Kioussis, D.2    Robey, E.3
  • 25
    • 0028904213 scopus 로고
    • + T cell lineages: A new perspective on thymic commitment and selection
    • + T cell lineages: a new perspective on thymic commitment and selection. Immunity 2: 413-425.
    • (1995) Immunity , vol.2 , pp. 413-425
    • Suzuki, H.1    Punt, J.A.2    Granger, L.G.3    Singer, A.4
  • 29
    • 0031054634 scopus 로고    scopus 로고
    • Asynchronous coreceptor downregulation after positive thymic selection: Prolonged maintenance of the double positive state in CD8 lineage differentiation due to sustained biosynthesis of the CD4 coreceptor
    • Barthlott, T., H. Kohler, and K. Eichmann. 1997. Asynchronous coreceptor downregulation after positive thymic selection: prolonged maintenance of the double positive state in CD8 lineage differentiation due to sustained biosynthesis of the CD4 coreceptor. J. Exp. Med. 185: 357-362.
    • (1997) J. Exp. Med. , vol.185 , pp. 357-362
    • Barthlott, T.1    Kohler, H.2    Eichmann, K.3
  • 33
    • 0030916961 scopus 로고    scopus 로고
    • Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner
    • Sebzda, E., M. Choi, W. P. Fung-Leung, T. W. Mak, and P. S. Ohashi. 1997. Peptide-induced positive selection of TCR transgenic thymocytes in a coreceptor-independent manner. Immunity 6: 643-653.
    • (1997) Immunity , vol.6 , pp. 643-653
    • Sebzda, E.1    Choi, M.2    Fung-Leung, W.P.3    Mak, T.W.4    Ohashi, P.S.5
  • 34
    • 0037415559 scopus 로고    scopus 로고
    • + thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection
    • + thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection. J. Exp. Med. 197: 363-373.
    • (2003) J. Exp. Med. , vol.197 , pp. 363-373
    • Liu, X.1    Adams, A.2    Wildt, K.F.3    Aronow, B.4    Feigenbaum, L.5    Bosselut, R.6
  • 37
    • 0029788694 scopus 로고    scopus 로고
    • c-Krox binds to several sites in the promoter of both mouse type I collagen genes: Structure/function study and developmental expression analysis
    • Galera, P., R. W. Park, P. Ducy, M. G. Mattei, and G. Karsenty. 1996. c-Krox binds to several sites in the promoter of both mouse type I collagen genes: structure/function study and developmental expression analysis. J. Biol. Chem. 271: 21331-21339.
    • (1996) J. Biol. Chem. , vol.271 , pp. 21331-21339
    • Galera, P.1    Park, R.W.2    Ducy, P.3    Mattei, M.G.4    Karsenty, G.5
  • 40
    • 0026483786 scopus 로고
    • Zap-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain
    • Chan, A. C., M. Iwashima, C. W. Turck, and A. Weiss. 1992. Zap-70: a 70 kd protein-tyrosine kinase that associates with the TCR ζ chain. Cell 71: 649-662.
    • (1992) Cell , vol.71 , pp. 649-662
    • Chan, A.C.1    Iwashima, M.2    Turck, C.W.3    Weiss, A.4
  • 43
    • 0036533386 scopus 로고    scopus 로고
    • New perspectives on a developmental dilemma: The kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision
    • Singer, A. 2002. New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision. Curr. Opin. Immunol. 14: 207-215.
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 207-215
    • Singer, A.1
  • 47
    • 0032445491 scopus 로고    scopus 로고
    • CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity
    • Azzam, H. S., A. Grinberg, K. Lui, H. Shen, E. W. Shores, and P. E. Love. 1998. CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity. J. Exp. Med. 188: 2301-2311.
    • (1998) J. Exp. Med. , vol.188 , pp. 2301-2311
    • Azzam, H.S.1    Grinberg, A.2    Lui, K.3    Shen, H.4    Shores, E.W.5    Love, P.E.6
  • 48
    • 0026598333 scopus 로고
    • Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition
    • Kaye, J., N. J. Vasquez, and S. M. Hedrick. 1992. Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognition. J. Immunol. 148: 3342-3353.
    • (1992) J. Immunol. , vol.148 , pp. 3342-3353
    • Kaye, J.1    Vasquez, N.J.2    Hedrick, S.M.3
  • 49
    • 15244342946 scopus 로고    scopus 로고
    • Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes
    • Sato, T., S. Ohno, T. Hayashi, C. Sato, K. Kohu, M. Satake, and S. Habu. 2005. Dual functions of Runx proteins for reactivating CD8 and silencing CD4 at the commitment process into CD8 thymocytes. Immunity 22: 317-328.
    • (2005) Immunity , vol.22 , pp. 317-328
    • Sato, T.1    Ohno, S.2    Hayashi, T.3    Sato, C.4    Kohu, K.5    Satake, M.6    Habu, S.7
  • 50
    • 0025933951 scopus 로고
    • Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice
    • Huesmann, M., B. Scott, P. Kisielow, and H. von Boehmer. 1991. Kinetics and efficacy of positive selection in the thymus of normal and T cell receptor transgenic mice. Cell 66: 533-540.
    • (1991) Cell , vol.66 , pp. 533-540
    • Huesmann, M.1    Scott, B.2    Kisielow, P.3    Von Boehmer, H.4
  • 51
    • 0041488620 scopus 로고    scopus 로고
    • The influence of the thymic environment on the CD4-versus-CD8 T lineage decision
    • Canelles, M., M. L. Park, O. M. Schwartz, and B. J. Fowlkes. 2003. The influence of the thymic environment on the CD4-versus-CD8 T lineage decision. Nat. Immunol. 4: 756-764.
    • (2003) Nat. Immunol. , vol.4 , pp. 756-764
    • Canelles, M.1    Park, M.L.2    Schwartz, O.M.3    Fowlkes, B.J.4
  • 52
    • 14844286998 scopus 로고    scopus 로고
    • Receptor signals and nuclear events in CD4 and CD8 T cell lineage commitment
    • Laky, K., and B. Fowlkes. 2005. Receptor signals and nuclear events in CD4 and CD8 T cell lineage commitment. Curr. Opin. Immunol. 17: 116-121.
    • (2005) Curr. Opin. Immunol. , vol.17 , pp. 116-121
    • Laky, K.1    Fowlkes, B.2
  • 53
    • 0033842737 scopus 로고    scopus 로고
    • The thymus and negative selection
    • Kishimoto, H., and J. Sprent. 2000. The thymus and negative selection. Immunol. Res. 21: 315-323.
    • (2000) Immunol. Res. , vol.21 , pp. 315-323
    • Kishimoto, H.1    Sprent, J.2
  • 55
    • 0344500762 scopus 로고    scopus 로고
    • hi thymocytes does not require T cell receptor-major histocompatibility complex contact
    • hi thymocytes does not require T cell receptor-major histocompatibility complex contact. J. Exp. Med. 190: 757-764.
    • (1999) J. Exp. Med. , vol.190 , pp. 757-764
    • Dyall, R.1    Nikolic-Zugic, J.2
  • 59
    • 0024288672 scopus 로고
    • T-cell development: Accessories or coreceptors?
    • Janeway, C. A. J. 1988. T-cell development: accessories or coreceptors? Nature 335: 208-210.
    • (1988) Nature , vol.335 , pp. 208-210
    • Janeway, C.A.J.1
  • 60
    • 0027153897 scopus 로고
    • Another view of the selective model of thymocyte selection
    • Chan, S. H., D. Cosgrove, C. Waltzinger, C. Benoist, and D. Mathis. 1993. Another view of the selective model of thymocyte selection. Cell 73: 225-236.
    • (1993) Cell , vol.73 , pp. 225-236
    • Chan, S.H.1    Cosgrove, D.2    Waltzinger, C.3    Benoist, C.4    Mathis, D.5
  • 61
    • 0027164960 scopus 로고
    • + thymocytes: Selection rather than instruction?
    • + thymocytes: selection rather than instruction? Science 261: 911-915.
    • (1993) Science , vol.261 , pp. 911-915
    • Van Meerwijk, J.P.1    Germain, R.N.2
  • 62
    • 0025751550 scopus 로고
    • Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes
    • Sentman, C. L., J. R. Shutter, D. Hockenbery, O. Kanagawa, and S. J. Korsmeyer. 1991. Bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes. Cell 67: 879-888.
    • (1991) Cell , vol.67 , pp. 879-888
    • Sentman, C.L.1    Shutter, J.R.2    Hockenbery, D.3    Kanagawa, O.4    Korsmeyer, S.J.5
  • 64
    • 0029843941 scopus 로고    scopus 로고
    • Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation
    • Linette, G. P., Y. Li, K. Roth, and S. J. Korsmeyer. 1996. Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation. Proc. Natl Acad. Sci. USA 93: 9545-9552.
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 9545-9552
    • Linette, G.P.1    Li, Y.2    Roth, K.3    Korsmeyer, S.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.