In vitro evidence that cytokine receptor signals are required for differentiation of double positive thymocytes into functionally mature CD8+ T cells

Journal of Experimental Medicine

Volumn 197, Issue 4, 2003, Pages 475-487

  Yu, Qing ^a   Erman, Batu ^a   Bhandoola, Avinash ^a,b   Sharrow, Susan O ^a   Singer, Alfred ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Coreceptor reversal; IL 7; Kinetic signaling; Positive selection

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE RECEPTOR; GLUCOSE TRANSPORTER; INTERLEUKIN 7 RECEPTOR; PROTEIN BCL 2; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL MATURATION; CELL SELECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; GENE SILENCING; IN VITRO STUDY; METABOLIC ACTIVATION; MOUSE; NONHUMAN; NUTRIENT UPTAKE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; UPREGULATION;

ANIMALS; ANTIGENS, CD4; ANTIGENS, CD8; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; INTERFERON TYPE II; INTERLEUKIN-7; MICE; MICE, INBRED C57BL; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, INTERLEUKIN-7; T-LYMPHOCYTE SUBSETS;

EID: 0037450683     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021765     Document Type: Article

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