Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells

Journal of Experimental Medicine

Volumn 197, Issue 12, 2003, Pages 1709-1719

  Bosselut, Remy ^a   Guinter, Terry I ^a   Sharrow, Susan O ^a   Singer, Alfred ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Coreceptor reversal; Kinetic signaling; Lineage commitment; Positive selection

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PRONASE; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL LINEAGE; CELL SELECTION; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; GENE SILENCING; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; THYMOCYTE; TRANSGENIC MOUSE;

ANIMALS; ANTIGENS, CD8; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; DOWN-REGULATION; FLOW CYTOMETRY; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; MAJOR HISTOCOMPATIBILITY COMPLEX; MICE; MICE, TRANSGENIC; SIGNAL TRANSDUCTION; T-LYMPHOCYTE SUBSETS; THYMUS GLAND;

EID: 0037867040     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20030170     Document Type: Article

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