Restricting Zap70 expression to CD4+CD8+ thymocytes reveals a T cell receptor-dependent proofreading mechanism controlling the completion of positive selection

Journal of Experimental Medicine

Volumn 197, Issue 3, 2003, Pages 363-373

  Liu, Xiaolong ^a   Adams, Anthony ^a   Wildt, Kathryn F ^a   Aronow, Bruce ^b   Feigenbaum, Lionel ^c   Bosselut, Rémy ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c SAIC FREDERICK INC   (United States)

Author keywords

Adenosine deaminase; Antigen receptor rearrangement; T cell development; Thymus; Transgenic mice

Indexed keywords

ADENOSINE DEAMINASE; CD4 ANTIGEN; CD8 ANTIGEN; COMPLEMENTARY DNA; LYMPHOCYTE ANTIGEN RECEPTOR; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MATURATION; ENHANCER REGION; GENE REARRANGEMENT; GENOTYPE; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE; THYMOCYTE; THYMUS; TRANSGENIC MOUSE;

ADENOSINE DEAMINASE; AMINO ACID SEQUENCE; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; GENE EXPRESSION; GENE REARRANGEMENT, T-LYMPHOCYTE; HUMANS; MICE; MICE, TRANSGENIC; MOLECULAR SEQUENCE DATA; PROTEIN-TYROSINE KINASES; SELECTION (GENETICS); SIGNAL TRANSDUCTION; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0037415559     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.20021698     Document Type: Article

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