Deletion of the CD4 silencer element supports a stochastic mechanism of thymocyte lineage commitment

Nature Immunology

Volumn 2, Issue 12, 2001, Pages 1167-1173

  Leung, Ray K M ^a   Thomson, Kirsty ^a   Gallimore, Awen ^a   Jones, Emma ^a   Van Den Broek, Maries ^b   Sierro, Sophie ^b   Alsheikhly, Abdul Razzak ^a   McMichael, Andrew ^c   Rahemtulla, Amin ^a,d  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; GENE DELETION; GENE TARGETING; GENETIC RECOMBINATION; GERM LINE; IMMATURITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SILENCER GENE; T LYMPHOCYTE; THYMOCYTE;

ANIMALS; ANTIGENS, CD4; CD4-POSITIVE T-LYMPHOCYTES; CELL LINEAGE; DOWN-REGULATION; GENE SILENCING; GENE TARGETING; HISTOCOMPATIBILITY ANTIGENS CLASS II; IMMUNOPHENOTYPING; LYMPH NODES; MICE; MICE, INBRED C57BL; REGULATORY SEQUENCES, NUCLEIC ACID; RESPONSE ELEMENTS; SEQUENCE DELETION; STOCHASTIC PROCESSES; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, CYTOTOXIC; THYMUS GLAND;

EID: 0035202314     PISSN: 15292908     EISSN: None     Source Type: Journal    
DOI: 10.1038/ni733     Document Type: Article

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