-
1
-
-
0025603722
-
A novel protein-tyrosine kinase, tec, is preferentially expressed in liver
-
Mano H, Ishikawa F, Nishida J, Hirai H, Takaku F: A novel protein-tyrosine kinase, tec, is preferentially expressed in liver. Oncogene 1990;5:1781-1786.
-
(1990)
Oncogene
, vol.5
, pp. 1781-1786
-
-
Mano, H.1
Ishikawa, F.2
Nishida, J.3
Hirai, H.4
Takaku, F.5
-
2
-
-
0027399081
-
Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
-
Tsukada S, Saffran DC, Rawlings DJ, Parolini O, Allen RC, Klisak I, Sparkes RS, Kubagawa H, Mohandas T, Quan S, et al: Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia. Cell 1993;72:279-290.
-
(1993)
Cell
, vol.72
, pp. 279-290
-
-
Tsukada, S.1
Saffran, D.C.2
Rawlings, D.J.3
Parolini, O.4
Allen, R.C.5
Klisak, I.6
Sparkes, R.S.7
Kubagawa, H.8
Mohandas, T.9
Quan, S.10
-
3
-
-
0027441332
-
The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
-
Vetrie D, Vorechovsky I, Sideras P, Holland J, Davies A, Flinter F, Hammarstrom L, Kinnon C, Levinsky R, Bobrow M, et al: The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases. Nature 1993;361:226-233.
-
(1993)
Nature
, vol.361
, pp. 226-233
-
-
Vetrie, D.1
Vorechovsky, I.2
Sideras, P.3
Holland, J.4
Davies, A.5
Flinter, F.6
Hammarstrom, L.7
Kinnon, C.8
Levinsky, R.9
Bobrow, M.10
-
4
-
-
0027305921
-
Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice
-
Rawlings DJ, Saffran DC, Tsukada S, Largaespada DA, Grimaldi JC, Cohen L, Mohr RN, Bazan JF, Howard M, Copeland NG, et al: Mutation of unique region of Bruton's tyrosine kinase in immunodeficient XID mice. Science 1993;261:358-361.
-
(1993)
Science
, vol.261
, pp. 358-361
-
-
Rawlings, D.J.1
Saffran, D.C.2
Tsukada, S.3
Largaespada, D.A.4
Grimaldi, J.C.5
Cohen, L.6
Mohr, R.N.7
Bazan, J.F.8
Howard, M.9
Copeland, N.G.10
-
5
-
-
0027199298
-
Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells
-
Yamada N, Kawakami Y, Kimura H, Fukamachi H, Baier G, Altman A, Kato T, Inagaki Y, Kawakami T: Structure and expression of novel protein-tyrosine kinases, Emb and Emt, in hematopoietic cells. Biochem Biophys Res Commun 1993;192:231-240.
-
(1993)
Biochem Biophys Res Commun
, vol.192
, pp. 231-240
-
-
Yamada, N.1
Kawakami, Y.2
Kimura, H.3
Fukamachi, H.4
Baier, G.5
Altman, A.6
Kato, T.7
Inagaki, Y.8
Kawakami, T.9
-
6
-
-
0027944227
-
BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2
-
Tamagnone L, Lahtinen I, Mustonen T, Virtaneva K, Francis F, Muscatelli F, Alitalo R, Smith CI, Larsson C, Alitalo K: BMX, a novel nonreceptor tyrosine kinase gene of the BTK/ITK/TEC/TXK family located in chromosome Xp22.2. Oncogene 1994;9:3683-3688.
-
(1994)
Oncogene
, vol.9
, pp. 3683-3688
-
-
Tamagnone, L.1
Lahtinen, I.2
Mustonen, T.3
Virtaneva, K.4
Francis, F.5
Muscatelli, F.6
Alitalo, R.7
Smith, C.I.8
Larsson, C.9
Alitalo, K.10
-
8
-
-
0026453395
-
itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2
-
Siliciano JD, Morrow TA, Desiderio SV: itk, a T-cell-specific tyrosine kinase gene inducible by interleukin 2. Proc Natl Acad Sci USA 1992;89:11194-11198.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 11194-11198
-
-
Siliciano, J.D.1
Morrow, T.A.2
Desiderio, S.V.3
-
9
-
-
0027393602
-
Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk
-
Heyeck SD, Berg LJ: Developmental regulation of a murine T-cell-specific tyrosine kinase gene, Tsk. Proc Natl Acad Sci USA 1993;90:669-673.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 669-673
-
-
Heyeck, S.D.1
Berg, L.J.2
-
10
-
-
0028292588
-
TXK, a novel human tyrosine kinase expressed in T cells shares sequence identity with Tec family kinases and maps to 4p12
-
Haire RN, Ohta Y, Lewis JE, Fu SM, Kroisel P, Litman GW: TXK, a novel human tyrosine kinase expressed in T cells shares sequence identity with Tec family kinases and maps to 4p12. Hum Mol Genet 1994;3:897-901.
-
(1994)
Hum Mol Genet
, vol.3
, pp. 897-901
-
-
Haire, R.N.1
Ohta, Y.2
Lewis, J.E.3
Fu, S.M.4
Kroisel, P.5
Litman, G.W.6
-
11
-
-
0028910356
-
Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage
-
Hu Q, Davidson D, Schwartzberg PL, Macchiarini F, Lenardo MJ, Bluestone JA, Matis LA: Identification of Rlk, a novel protein tyrosine kinase with predominant expression in the T cell lineage. J Biol Chem 1995;270:1928-1934.
-
(1995)
J Biol Chem
, vol.270
, pp. 1928-1934
-
-
Hu, Q.1
Davidson, D.2
Schwartzberg, P.L.3
Macchiarini, F.4
Lenardo, M.J.5
Bluestone, J.A.6
Matis, L.A.7
-
12
-
-
0001584969
-
The Tec family of cytoplasmic tyrosine kinases: Mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species
-
Smith CI, Islam TC, Mattsson PT, Mohamed AJ, Nore BF, Vihinen M: The Tec family of cytoplasmic tyrosine kinases: Mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species. Bioessays 2001;23:436-446.
-
(2001)
Bioessays
, vol.23
, pp. 436-446
-
-
Smith, C.I.1
Islam, T.C.2
Mattsson, P.T.3
Mohamed, A.J.4
Nore, B.F.5
Vihinen, M.6
-
13
-
-
0027977799
-
SH2/SH3 signaling proteins
-
Schlessinger J: SH2/SH3 signaling proteins. Curr Opin Genet Dev 1994;4:25-30.
-
(1994)
Curr Opin Genet Dev
, vol.4
, pp. 25-30
-
-
Schlessinger, J.1
-
15
-
-
0031029781
-
Regulatory intramolecular association in a tyrosine kinase of the Tec family
-
Andreotti AH, Bunnell SC, Feng S, Berg LJ, Schreiber SL: Regulatory intramolecular association in a tyrosine kinase of the Tec family. Nature 1997;385:93-97.
-
(1997)
Nature
, vol.385
, pp. 93-97
-
-
Andreotti, A.H.1
Bunnell, S.C.2
Feng, S.3
Berg, L.J.4
Schreiber, S.L.5
-
16
-
-
0027980301
-
Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction
-
Cheng G, Ye ZS, Baltimore D: Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction. Proc Natl Acad Sci USA 1994;91:8152-8155.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 8152-8155
-
-
Cheng, G.1
Ye, Z.S.2
Baltimore, D.3
-
17
-
-
0032961364
-
rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases
-
Debnath J, Chamorro M, Czar MJ, Schaeffer EM, Lenardo MJ, Varmus HE, Schwartzberg PL: rlk/TXK encodes two forms of a novel cysteine string tyrosine kinase activated by Src family kinases. Mol Cell Biol 1999;19:1498-1507.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 1498-1507
-
-
Debnath, J.1
Chamorro, M.2
Czar, M.J.3
Schaeffer, E.M.4
Lenardo, M.J.5
Varmus, H.E.6
Schwartzberg, P.L.7
-
18
-
-
0027389121
-
Expression of a novel form of Tec kinase in hematopoietic cells and mapping of the gene to chromosome 5 near Kit
-
Mano H, Mano K, Tang B, Koehler M, Yi T, Gilbert DJ, Jenkins NA, Copeland NG, Ihle JN: Expression of a novel form of Tec kinase in hematopoietic cells and mapping of the gene to chromosome 5 near Kit. Oncogene 1993;8:417-424.
-
(1993)
Oncogene
, vol.8
, pp. 417-424
-
-
Mano, H.1
Mano, K.2
Tang, B.3
Koehler, M.4
Yi, T.5
Gilbert, D.J.6
Jenkins, N.A.7
Copeland, N.G.8
Ihle, J.N.9
-
19
-
-
0028049537
-
Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking
-
Kawakami Y, Yao L, Miura T, Tsukada S, Witte ON, Kawakami T: Tyrosine phosphorylation and activation of Bruton tyrosine kinase upon Fc epsilon RI cross-linking. Mol Cell Biol 1994;14:5108-5113.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 5108-5113
-
-
Kawakami, Y.1
Yao, L.2
Miura, T.3
Tsukada, S.4
Witte, O.N.5
Kawakami, T.6
-
20
-
-
0029165836
-
Activation and interaction with protein kinase C of a cytoplasmic tyrosine kinase, Itk/Tsk/Emt, on Fc epsilon RI cross-linking on mast cells
-
Kawakami Y, Yao L, Tashiro M, Gibson S, Mills GB, Kawakami T: Activation and interaction with protein kinase C of a cytoplasmic tyrosine kinase, Itk/Tsk/Emt, on Fc epsilon RI cross-linking on mast cells. J Immunol 1995;155:3556-3562.
-
(1995)
J Immunol
, vol.155
, pp. 3556-3562
-
-
Kawakami, Y.1
Yao, L.2
Tashiro, M.3
Gibson, S.4
Mills, G.B.5
Kawakami, T.6
-
21
-
-
0029127751
-
Murine txk: A protein tyrosine kinase gene regulated by T cell activation
-
Sommers CL, Huang K, Shores EW, Grinberg A, Charlick DA, Kozak CA, Love PE: Murine txk: A protein tyrosine kinase gene regulated by T cell activation. Oncogene 1995;11:245-251.
-
(1995)
Oncogene
, vol.11
, pp. 245-251
-
-
Sommers, C.L.1
Huang, K.2
Shores, E.W.3
Grinberg, A.4
Charlick, D.A.5
Kozak, C.A.6
Love, P.E.7
-
22
-
-
0029902069
-
High expression of the tec gene product in murine testicular germ cells and erythroblasts
-
Kazama A, Mano H, Morishita Y, Mori S: High expression of the tec gene product in murine testicular germ cells and erythroblasts. Pathol Int 1996;46:341-347.
-
(1996)
Pathol Int
, vol.46
, pp. 341-347
-
-
Kazama, A.1
Mano, H.2
Morishita, Y.3
Mori, S.4
-
23
-
-
0034669936
-
Stem cell factor induces phosphatidylinositol 3′-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells
-
van Dijk TB, van Den Akker E, Amelsvoort MP, Mano H, Lowenberg B, von Lindern M: Stem cell factor induces phosphatidylinositol 3′-kinase- dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells. Blood 2000;96:3406-3413.
-
(2000)
Blood
, vol.96
, pp. 3406-3413
-
-
Van Dijk, T.B.1
Van Den Akker, E.2
Amelsvoort, M.P.3
Mano, H.4
Lowenberg, B.5
Von Lindern, M.6
-
24
-
-
17544400277
-
An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells
-
Whyatt D, Lindeboom F, Karis A, Ferreira R, Milot E, Hendriks R, de Bruijn M, Langeveld A, Gribnau J, Grosveld F, Philipsen S: An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells. Nature 2000;406:519-524.
-
(2000)
Nature
, vol.406
, pp. 519-524
-
-
Whyatt, D.1
Lindeboom, F.2
Karis, A.3
Ferreira, R.4
Milot, E.5
Hendriks, R.6
De Bruijn, M.7
Langeveld, A.8
Gribnau, J.9
Grosveld, F.10
Philipsen, S.11
-
25
-
-
0032497629
-
A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen
-
Quek LS, Bolen J, Watson SP: A role for Bruton's tyrosine kinase (Btk) in platelet activation by collagen. Curr Biol 1998;8:1137-1140.
-
(1998)
Curr Biol
, vol.8
, pp. 1137-1140
-
-
Quek, L.S.1
Bolen, J.2
Watson, S.P.3
-
26
-
-
0031559834
-
Integrin-dependent tyrosine phosphorylation and cytoskeletal translocation of Tec in thrombin-activated platelets
-
Laffargue M, Monnereau L, Tuech J, Ragab A, Ragab-Thomas J, Payrastre B, Raynal P, Chap H: Integrin-dependent tyrosine phosphorylation and cytoskeletal translocation of Tec in thrombin-activated platelets. Biochem Biophys Res Commun 1997;238:247-251.
-
(1997)
Biochem Biophys Res Commun
, vol.238
, pp. 247-251
-
-
Laffargue, M.1
Monnereau, L.2
Tuech, J.3
Ragab, A.4
Ragab-Thomas, J.5
Payrastre, B.6
Raynal, P.7
Chap, H.8
-
27
-
-
0029791422
-
BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias
-
Kaukonen J, Lahtinen I, Laine S, Alitalo K, Palotie A: BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias. Br J Haematol 1996;94:455-460.
-
(1996)
Br J Haematol
, vol.94
, pp. 455-460
-
-
Kaukonen, J.1
Lahtinen, I.2
Laine, S.3
Alitalo, K.4
Palotie, A.5
-
28
-
-
0030662106
-
Predominant expression of murine Bmx tyrosine kinase in the granulo-monocytic lineage
-
Weil D, Power MA, Smith SI, Li CL: Predominant expression of murine Bmx tyrosine kinase in the granulo-monocytic lineage. Blood 1997;90:4332-4340.
-
(1997)
Blood
, vol.90
, pp. 4332-4340
-
-
Weil, D.1
Power, M.A.2
Smith, S.I.3
Li, C.L.4
-
29
-
-
0038544296
-
Bruton's tyrosine kinase is required for lipopolysaccharide-induced tumor necrosis factor alpha production
-
Horwood NJ, Mahon T, McDaid JP, Campbell J, Mano H, Brennan FM, Webster D, Foxwell BM: Bruton's tyrosine kinase is required for lipopolysaccharide- induced tumor necrosis factor alpha production. J Exp Med 2003;197:1603-1611.
-
(2003)
J Exp Med
, vol.197
, pp. 1603-1611
-
-
Horwood, N.J.1
Mahon, T.2
McDaid, J.P.3
Campbell, J.4
Mano, H.5
Brennan, F.M.6
Webster, D.7
Foxwell, B.M.8
-
30
-
-
0037077219
-
Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. Implication of phosphatidylinositol 3-kinases
-
Lachance G, Levasseur S, Naccache PH: Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. Implication of phosphatidylinositol 3-kinases. J Biol Chem 2002;277:21537-21541.
-
(2002)
J Biol Chem
, vol.277
, pp. 21537-21541
-
-
Lachance, G.1
Levasseur, S.2
Naccache, P.H.3
-
31
-
-
0038723629
-
Bruton's tyrosine kinase defect in dendritic cells from X-linked agammaglobulinaemia patients does not influence their differentiation, maturation and antigen-presenting cell function
-
Gagliardi MC, Finocchi A, Orlandi P, Cursi L, Cancrini C, Moschese V, Miyawaki T, Rossi P: Bruton's tyrosine kinase defect in dendritic cells from X-linked agammaglobulinaemia patients does not influence their differentiation, maturation and antigen-presenting cell function. Clin Exp Immunol 2003;133:115-122.
-
(2003)
Clin Exp Immunol
, vol.133
, pp. 115-122
-
-
Gagliardi, M.C.1
Finocchi, A.2
Orlandi, P.3
Cursi, L.4
Cancrini, C.5
Moschese, V.6
Miyawaki, T.7
Rossi, P.8
-
32
-
-
0034595656
-
The genetic program of hematopoietic stem cells
-
Phillips RL, Ernst RE, Brunk B, Ivanova N, Mahan MA, Deanehan JK, Moore KA, Overton GC, Lemischka IR: The genetic program of hematopoietic stem cells. Science 2000;288:1635-1640.
-
(2000)
Science
, vol.288
, pp. 1635-1640
-
-
Phillips, R.L.1
Ernst, R.E.2
Brunk, B.3
Ivanova, N.4
Mahan, M.A.5
Deanehan, J.K.6
Moore, K.A.7
Overton, G.C.8
Lemischka, I.R.9
-
33
-
-
0347087492
-
Bruton's tyrosine kinase phosphorylates CREB at Ser-133 during neuronal differentiation in immortalized hippocampal progenitor cells
-
Yang EJ, Yoon JH, Chung KC: Bruton's tyrosine kinase phosphorylates CREB at Ser-133 during neuronal differentiation in immortalized hippocampal progenitor cells. J Biol Chem 2004;279:1827-1837.
-
(2004)
J Biol Chem
, vol.279
, pp. 1827-1837
-
-
Yang, E.J.1
Yoon, J.H.2
Chung, K.C.3
-
34
-
-
0034092567
-
Tec family kinases in lymphocyte signaling and function
-
Schaeffer EM, Schwartzberg PL: Tec family kinases in lymphocyte signaling and function. Curr Opin Immunol 2000;12:282-288.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 282-288
-
-
Schaeffer, E.M.1
Schwartzberg, P.L.2
-
36
-
-
0036604985
-
New insights into the regulation and function of Tec family tyrosine kinases in the immune system
-
Miller AT, Berg LJ: New insights into the regulation and function of Tec family tyrosine kinases in the immune system. Curr Opin Immunol 2002;14:331-340.
-
(2002)
Curr Opin Immunol
, vol.14
, pp. 331-340
-
-
Miller, A.T.1
Berg, L.J.2
-
37
-
-
0034695633
-
Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade
-
Bunnell SC, Diehn M, Yaffe MB, Findell PR, Cantley LC, Berg LJ: Biochemical interactions integrating Itk with the T cell receptor-initiated signaling cascade. J Biol Chem 2000;275:2219-2230.
-
(2000)
J Biol Chem
, vol.275
, pp. 2219-2230
-
-
Bunnell, S.C.1
Diehn, M.2
Yaffe, M.B.3
Findell, P.R.4
Cantley, L.C.5
Berg, L.J.6
-
38
-
-
0033695960
-
Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex
-
Guo B, Kato RM, Garcia-Lloret M, Wahl MI, Rawlings DJ: Engagement of the human pre-B cell receptor generates a lipid raft-dependent calcium signaling complex. Immunity 2000;13:243-253.
-
(2000)
Immunity
, vol.13
, pp. 243-253
-
-
Guo, B.1
Kato, R.M.2
Garcia-Lloret, M.3
Wahl, M.I.4
Rawlings, D.J.5
-
39
-
-
0033811659
-
Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation
-
Shan X, Czar MJ, Bunnell SC, Liu P, Liu Y, Schwartzberg PL, Wange RL: Deficiency of PTEN in Jurkat T cells causes constitutive localization of Itk to the plasma membrane and hyperresponsiveness to CD3 stimulation. Mol Cell Biol 2000;20:6945-6957.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 6945-6957
-
-
Shan, X.1
Czar, M.J.2
Bunnell, S.C.3
Liu, P.4
Liu, Y.5
Schwartzberg, P.L.6
Wange, R.L.7
-
40
-
-
0035868761
-
A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor
-
Woods ML, Kivens WJ, Adelsman MA, Qiu Y, August A, Shimizu Y: A novel function for the Tec family tyrosine kinase Itk in activation of beta 1 integrins by the T-cell receptor. EMBO J 2001;20:1232-1244.
-
(2001)
EMBO J
, vol.20
, pp. 1232-1244
-
-
Woods, M.L.1
Kivens, W.J.2
Adelsman, M.A.3
Qiu, Y.4
August, A.5
Shimizu, Y.6
-
41
-
-
0030018304
-
A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2
-
Takata M, Kurosaki T: A role for Bruton's tyrosine kinase in B cell antigen receptor-mediated activation of phospholipase C-gamma 2. J Exp Med 1996;184:31-40.
-
(1996)
J Exp Med
, vol.184
, pp. 31-40
-
-
Takata, M.1
Kurosaki, T.2
-
42
-
-
0032055476
-
2+ following B-cell receptor activation
-
2+ following B-cell receptor activation. EMBO J 1998;17:1973-1985.
-
(1998)
EMBO J
, vol.17
, pp. 1973-1985
-
-
Fluckiger, A.C.1
Li, Z.2
Kato, R.M.3
Wahl, M.I.4
Ochs, H.D.5
Longnecker, R.6
Kinet, J.P.7
Witte, O.N.8
Scharenberg, A.M.9
Rawlings, D.J.10
-
43
-
-
0032543221
-
T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells
-
Liu KQ, Bunnell SC, Gurniak CB, Berg LJ: T cell receptor-initiated calcium release is uncoupled from capacitative calcium entry in Itk-deficient T cells. J Exp Med 1998;187:1721-1727.
-
(1998)
J Exp Med
, vol.187
, pp. 1721-1727
-
-
Liu, K.Q.1
Bunnell, S.C.2
Gurniak, C.B.3
Berg, L.J.4
-
44
-
-
0033597440
-
Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity
-
Schaeffer EM, Debnath J, Yap G, McVicar D, Liao XC, Littman DR, Sher A, Varmus HE, Lenardo MJ, Schwartzberg PL: Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity. Science 1999;284:638-641.
-
(1999)
Science
, vol.284
, pp. 638-641
-
-
Schaeffer, E.M.1
Debnath, J.2
Yap, G.3
McVicar, D.4
Liao, X.C.5
Littman, D.R.6
Sher, A.7
Varmus, H.E.8
Lenardo, M.J.9
Schwartzberg, P.L.10
-
45
-
-
0035339914
-
Differential roles of Lck and Itk in T cell response to antigen recognition revealed by calcium imaging and electron microscopy
-
Donnadieu E, Lang V, Bismuth G, Ellmeier W, Acuto O, Michel F, Trautmann A: Differential roles of Lck and Itk in T cell response to antigen recognition revealed by calcium imaging and electron microscopy. J Immunol 2001;166:5540-5549.
-
(2001)
J Immunol
, vol.166
, pp. 5540-5549
-
-
Donnadieu, E.1
Lang, V.2
Bismuth, G.3
Ellmeier, W.4
Acuto, O.5
Michel, F.6
Trautmann, A.7
-
46
-
-
0032550335
-
Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production
-
Hata D, Kawakami Y, Inagaki N, Lantz CS, Kitamura T, Khan WN, Maeda-Yamamoto M, Miura T, Han W, Hartman SE, Yao L, Nagai H, Goldfeld AE, Alt FW, Galli SJ, Witte ON, Kawakami T: Involvement of Bruton's tyrosine kinase in FcepsilonRI-dependent mast cell degranulation and cytokine production. J Exp Med 1998;187:1235-1247.
-
(1998)
J Exp Med
, vol.187
, pp. 1235-1247
-
-
Hata, D.1
Kawakami, Y.2
Inagaki, N.3
Lantz, C.S.4
Kitamura, T.5
Khan, W.N.6
Maeda-Yamamoto, M.7
Miura, T.8
Han, W.9
Hartman, S.E.10
Yao, L.11
Nagai, H.12
Goldfeld, A.E.13
Alt, F.W.14
Galli, S.J.15
Witte, O.N.16
Kawakami, T.17
-
47
-
-
0032701019
-
Interaction of SLP adaptors with the SH2 domain of Tec family kinases
-
Su YW, Zhang Y, Schweikert J, Koretzky GA, Reth M, Wienands J: Interaction of SLP adaptors with the SH2 domain of Tec family kinases. Eur J Immunol 1999;29:3702-3711.
-
(1999)
Eur J Immunol
, vol.29
, pp. 3702-3711
-
-
Su, Y.W.1
Zhang, Y.2
Schweikert, J.3
Koretzky, G.A.4
Reth, M.5
Wienands, J.6
-
48
-
-
0036676540
-
Beyond calcium: New signaling pathways for Tec family kinases
-
Takesono A, Finkelstein LD, Schwartzberg PL: Beyond calcium: New signaling pathways for Tec family kinases. J Cell Sci 2002;115:3039-3048.
-
(2002)
J Cell Sci
, vol.115
, pp. 3039-3048
-
-
Takesono, A.1
Finkelstein, L.D.2
Schwartzberg, P.L.3
-
49
-
-
0037307394
-
The role of Tec family kinases in T cell development and function
-
Lucas JA, Miller AT, Atherly LO, Berg LJ: The role of Tec family kinases in T cell development and function. Immunol Rev 2003;191:119-138.
-
(2003)
Immunol Rev
, vol.191
, pp. 119-138
-
-
Lucas, J.A.1
Miller, A.T.2
Atherly, L.O.3
Berg, L.J.4
-
50
-
-
0034002476
-
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation
-
Tsai YT, Su YH, Fang SS, Huang TN, Qiu Y, Jou YS, Shih HM, Kung HJ, Chen RH: Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation. Mol Cell Biol 2000;20:2043-2054.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 2043-2054
-
-
Tsai, Y.T.1
Su, Y.H.2
Fang, S.S.3
Huang, T.N.4
Qiu, Y.5
Jou, Y.S.6
Shih, H.M.7
Kung, H.J.8
Chen, R.H.9
-
51
-
-
0035903207
-
Transcription factor STAT5A is a substrate of Bruton's tyrosine kinase in B cells
-
Mahajan S, Vassilev A, Sun N, Ozer Z, Mao C, Uckun FM: Transcription factor STAT5A is a substrate of Bruton's tyrosine kinase in B cells. J Biol Chem 2001;276:31216-31228.
-
(2001)
J Biol Chem
, vol.276
, pp. 31216-31228
-
-
Mahajan, S.1
Vassilev, A.2
Sun, N.3
Ozer, Z.4
Mao, C.5
Uckun, F.M.6
-
52
-
-
0031038046
-
BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement
-
Yang W, Desiderio S: BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement. Proc Natl Acad Sci USA 1997;94:604-609.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 604-609
-
-
Yang, W.1
Desiderio, S.2
-
53
-
-
0034672041
-
The transcription factor Bright associates with Bruton's tyrosine kinase, the defective protein in immunodeficiency disease
-
Webb CF, Yamashita Y, Ayers N, Evetts S, Paulin Y, Conley ME, Smith EA: The transcription factor Bright associates with Bruton's tyrosine kinase, the defective protein in immunodeficiency disease. J Immunol 2000;165:6956-6965.
-
(2000)
J Immunol
, vol.165
, pp. 6956-6965
-
-
Webb, C.F.1
Yamashita, Y.2
Ayers, N.3
Evetts, S.4
Paulin, Y.5
Conley, M.E.6
Smith, E.A.7
-
54
-
-
0034781202
-
Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch 1alpha)
-
Perez-Villar JJ, O'Day K, Hewgill DH, Nadler SG, Kanner SB: Nuclear localization of the tyrosine kinase Itk and interaction of its SH3 domain with karyopherin alpha (Rch 1alpha). Int Immunol 2001;13:1265-1274.
-
(2001)
Int Immunol
, vol.13
, pp. 1265-1274
-
-
Perez-Villar, J.J.1
O'Day, K.2
Hewgill, D.H.3
Nadler, S.G.4
Kanner, S.B.5
-
55
-
-
0036498563
-
Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription
-
Takeba Y, Nagafuchi H, Takeno M, Kashiwakura J, Suzuki N: Txk, a member of nonreceptor tyrosine kinase of Tec family, acts as a Th1 cell-specific transcription factor and regulates IFN-gamma gene transcription. J Immunol 2002;168:2365-2370.
-
(2002)
J Immunol
, vol.168
, pp. 2365-2370
-
-
Takeba, Y.1
Nagafuchi, H.2
Takeno, M.3
Kashiwakura, J.4
Suzuki, N.5
-
56
-
-
0035660786
-
Role of Bruton's tyrosine kinase in B cell development
-
Maas A, Hendriks RW: Role of Bruton's tyrosine kinase in B cell development. Dev Immunol 2001;8:171-181.
-
(2001)
Dev Immunol
, vol.8
, pp. 171-181
-
-
Maas, A.1
Hendriks, R.W.2
-
57
-
-
0033013019
-
Bruton's tyrosine kinase controls a sustained calcium signal essential for B lineage development and function
-
Rawlings DJ: Bruton's tyrosine kinase controls a sustained calcium signal essential for B lineage development and function. Clin Immunol 1999;91:243-253.
-
(1999)
Clin Immunol
, vol.91
, pp. 243-253
-
-
Rawlings, D.J.1
-
58
-
-
0033965301
-
Mast cells in innate immunity
-
Mekori YA, Metcalfe DD: Mast cells in innate immunity. Immunol Rev 2000;173:131-140.
-
(2000)
Immunol Rev
, vol.173
, pp. 131-140
-
-
Mekori, Y.A.1
Metcalfe, D.D.2
-
59
-
-
0030472724
-
Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells
-
Costello PS, Turner M, Walters AE, Cunningham CN, Bauer PH, Downward J, Tybulewicz VL: Critical role for the tyrosine kinase Syk in signalling through the high affinity IgE receptor of mast cells. Oncogene 1996;13:2595-2605.
-
(1996)
Oncogene
, vol.13
, pp. 2595-2605
-
-
Costello, P.S.1
Turner, M.2
Walters, A.E.3
Cunningham, C.N.4
Bauer, P.H.5
Downward, J.6
Tybulewicz, V.L.7
-
60
-
-
0031092657
-
2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells
-
2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells. J Immunol 1997;158:2350-2355.
-
(1997)
J Immunol
, vol.158
, pp. 2350-2355
-
-
Nishizumi, H.1
Yamamoto, T.2
-
61
-
-
0034254791
-
Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation
-
Kawakami Y, Kitaura J, Satterthwaite AB, Kato RM, Asai K, Hartman SE, Maeda-Yamamoto M, Lowell CA, Rawlings DJ, Witte ON, Kawakami T: Redundant and opposing functions of two tyrosine kinases, Btk and Lyn, in mast cell activation. J Immunol 2000;165:1210-1219.
-
(2000)
J Immunol
, vol.165
, pp. 1210-1219
-
-
Kawakami, Y.1
Kitaura, J.2
Satterthwaite, A.B.3
Kato, R.M.4
Asai, K.5
Hartman, S.E.6
Maeda-Yamamoto, M.7
Lowell, C.A.8
Rawlings, D.J.9
Witte, O.N.10
Kawakami, T.11
-
62
-
-
0029738568
-
Spontaneous degranulation of cultured bone-marrow-derived immature mast cells from X-linked immunodeficient (Xid) mice
-
Dvorak AM, Miura T, Letourneau L, Ishizaka T, Kawakami T: Spontaneous degranulation of cultured bone-marrow-derived immature mast cells from X-linked immunodeficient (Xid) mice. Int Arch Allergy Immunol 1996;111:118-125.
-
(1996)
Int Arch Allergy Immunol
, vol.111
, pp. 118-125
-
-
Dvorak, A.M.1
Miura, T.2
Letourneau, L.3
Ishizaka, T.4
Kawakami, T.5
-
63
-
-
0030963609
-
Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity
-
Kawakami Y, Miura T, Bissonnette R, Hata D, Khan WN, Kitamura T, Maeda-Yamamoto M, Hartman SE, Yao L, Alt FW, Kawakami T: Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity. Proc Natl Acad Sci USA 1997;94:3938-3942.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 3938-3942
-
-
Kawakami, Y.1
Miura, T.2
Bissonnette, R.3
Hata, D.4
Khan, W.N.5
Kitamura, T.6
Maeda-Yamamoto, M.7
Hartman, S.E.8
Yao, L.9
Alt, F.W.10
Kawakami, T.11
-
64
-
-
0032079898
-
Bruton's tyrosine kinase-mediated interleukin-2 gene activation in mast cells. Dependence on the c-Jun N-terminal kinase activation pathway
-
Hata D, Kitaura J, Hartman SE, Kawakami Y, Yokota T, Kawakami T: Bruton's tyrosine kinase-mediated interleukin-2 gene activation in mast cells. Dependence on the c-Jun N-terminal kinase activation pathway. J Biol Chem 1998;273:10979-10987.
-
(1998)
J Biol Chem
, vol.273
, pp. 10979-10987
-
-
Hata, D.1
Kitaura, J.2
Hartman, S.E.3
Kawakami, Y.4
Yokota, T.5
Kawakami, T.6
-
65
-
-
0034605120
-
Akt-dependent cytokine production in mast cells
-
Kitaura J, Asai K, Maeda-Yamamoto M, Kawakami Y, Kikkawa U, Kawakami T: Akt-dependent cytokine production in mast cells. J Exp Med 2000;192:729-740.
-
(2000)
J Exp Med
, vol.192
, pp. 729-740
-
-
Kitaura, J.1
Asai, K.2
Maeda-Yamamoto, M.3
Kawakami, Y.4
Kikkawa, U.5
Kawakami, T.6
-
67
-
-
0038494921
-
Platelet-collagen interaction: Is GPVI the central receptor?
-
Nieswandt B, Watson SP: Platelet-collagen interaction: Is GPVI the central receptor? Blood 2003;102:449-461.
-
(2003)
Blood
, vol.102
, pp. 449-461
-
-
Nieswandt, B.1
Watson, S.P.2
-
68
-
-
0030833504
-
Syk and Fyn are required by mouse megakaryocytes for the rise in intracellular calcium induced by a collagen-related peptide
-
Melford SK, Turner M, Briddon SJ, Tybulewicz VL, Watson SP: Syk and Fyn are required by mouse megakaryocytes for the rise in intracellular calcium induced by a collagen-related peptide. J Biol Chem 1997;272:27539-27542.
-
(1997)
J Biol Chem
, vol.272
, pp. 27539-27542
-
-
Melford, S.K.1
Turner, M.2
Briddon, S.J.3
Tybulewicz, V.L.4
Watson, S.P.5
-
69
-
-
0031825550
-
Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI-Fc receptor gamma chain complex on human platelets
-
Ezumi Y, Shindoh K, Tsuji M, Takayama H: Physical and functional association of the Src family kinases Fyn and Lyn with the collagen receptor glycoprotein VI-Fc receptor gamma chain complex on human platelets. J Exp Med 1998;188:267-276.
-
(1998)
J Exp Med
, vol.188
, pp. 267-276
-
-
Ezumi, Y.1
Shindoh, K.2
Tsuji, M.3
Takayama, H.4
-
70
-
-
0033152398
-
Collagen mediates changes in intracellular calcium in primary mouse megakaryocytes through syk-dependent and -independent pathways
-
Briddon SJ, Melford SK, Turner M, Tybulewicz V, Watson SP: Collagen mediates changes in intracellular calcium in primary mouse megakaryocytes through syk-dependent and -independent pathways. Blood 1999;93:3847-3855.
-
(1999)
Blood
, vol.93
, pp. 3847-3855
-
-
Briddon, S.J.1
Melford, S.K.2
Turner, M.3
Tybulewicz, V.4
Watson, S.P.5
-
71
-
-
0033558230
-
Evidence for the involvement of p59fyn and p53/56lyn in collagen receptor signalling in human platelets
-
Briddon SJ, Watson SP: Evidence for the involvement of p59fyn and p53/56lyn in collagen receptor signalling in human platelets. Biochem J 1999;338/1:203-209.
-
(1999)
Biochem J
, vol.338
, Issue.1
, pp. 203-209
-
-
Briddon, S.J.1
Watson, S.P.2
-
72
-
-
0032102098
-
Collagen receptor signalling in platelets: Extending the role of the ITAM
-
Watson SP, Gibbins J: Collagen receptor signalling in platelets: Extending the role of the ITAM. Immunol Today 1998;19:260-264.
-
(1998)
Immunol Today
, vol.19
, pp. 260-264
-
-
Watson, S.P.1
Gibbins, J.2
-
73
-
-
0032575090
-
Tec is involved in G protein-coupled receptor- And integrin-mediated signalings in human blood platelets
-
Hamazaki Y, Kojima H, Mano H, Nagata Y, Todokoro K, Abe T, Nagasawa T: Tec is involved in G protein-coupled receptor- and integrin-mediated signalings in human blood platelets. Oncogene 1998;16:2773-2779.
-
(1998)
Oncogene
, vol.16
, pp. 2773-2779
-
-
Hamazaki, Y.1
Kojima, H.2
Mano, H.3
Nagata, Y.4
Todokoro, K.5
Abe, T.6
Nagasawa, T.7
-
74
-
-
17644442615
-
Rapid tyrosine phosphorylation and activation of Bruton's tyrosine/Tec kinases in platelets induced by collagen binding or CD32 cross-linking
-
Oda A, Ikeda Y, Ochs HD, Druker BJ, Ozaki K, Handa M, Ariga T, Sakiyama Y, Witte ON, Wahl MI: Rapid tyrosine phosphorylation and activation of Bruton's tyrosine/Tec kinases in platelets induced by collagen binding or CD32 cross-linking. Blood 2000;95:1663-1670.
-
(2000)
Blood
, vol.95
, pp. 1663-1670
-
-
Oda, A.1
Ikeda, Y.2
Ochs, H.D.3
Druker, B.J.4
Ozaki, K.5
Handa, M.6
Ariga, T.7
Sakiyama, Y.8
Witte, O.N.9
Wahl, M.I.10
-
75
-
-
0242411585
-
Tec regulates platelet activation by GPVI in the absence of Btk
-
Atkinson BT, Ellmeier W, Watson SP: Tec regulates platelet activation by GPVI in the absence of Btk. Blood 2003;102:3592-3599.
-
(2003)
Blood
, vol.102
, pp. 3592-3599
-
-
Atkinson, B.T.1
Ellmeier, W.2
Watson, S.P.3
-
76
-
-
0033008958
-
Phosphoinositide 3-kinase and integrin signalling are involved in activation of Bruton tyrosine kinase in thrombin-stimulated platelets
-
Laffargue M, Ragab-Thomas JM, Ragab A, Tuech J, Missy K, Monnereau L, Blank U, Plantavid M, Payrastre B, Raynal P, Chap H: Phosphoinositide 3-kinase and integrin signalling are involved in activation of Bruton tyrosine kinase in thrombin-stimulated platelets. FEBS Lett 1999;443:66-70.
-
(1999)
FEBS Lett
, vol.443
, pp. 66-70
-
-
Laffargue, M.1
Ragab-Thomas, J.M.2
Ragab, A.3
Tuech, J.4
Missy, K.5
Monnereau, L.6
Blank, U.7
Plantavid, M.8
Payrastre, B.9
Raynal, P.10
Chap, H.11
-
77
-
-
0034660077
-
Phosphatidylinositol 3,4,5-trisphosphate regulates Ca(2+) entry via btk in platelets and megakaryocytes without increasing phospholipase C activity
-
Pasquet JM, Quek L, Stevens C, Bobe R, Huber M, Duronio V, Krystal G, Watson SP: Phosphatidylinositol 3,4,5-trisphosphate regulates Ca(2+) entry via btk in platelets and megakaryocytes without increasing phospholipase C activity. EMBO J 2000;19:2793-2802.
-
(2000)
EMBO J
, vol.19
, pp. 2793-2802
-
-
Pasquet, J.M.1
Quek, L.2
Stevens, C.3
Bobe, R.4
Huber, M.5
Duronio, V.6
Krystal, G.7
Watson, S.P.8
-
78
-
-
0032785842
-
Regulation and function of WASp in platelets by the collagen receptor, glycoprotein VI
-
Gross BS, Wilde JI, Quek L, Chapel H, Nelson DL, Watson SP: Regulation and function of WASp in platelets by the collagen receptor, glycoprotein VI. Blood 1999;94:4166-4176.
-
(1999)
Blood
, vol.94
, pp. 4166-4176
-
-
Gross, B.S.1
Wilde, J.I.2
Quek, L.3
Chapel, H.4
Nelson, D.L.5
Watson, S.P.6
-
79
-
-
0032530670
-
Collagen induces tyrosine phosphorylation of Wiskott-Aldrich syndrome protein in human platelets
-
Oda A, Ochs HD, Druker BJ, Ozaki K, Watanabe C, Handa M, Miyakawa Y, Ikeda Y: Collagen induces tyrosine phosphorylation of Wiskott-Aldrich syndrome protein in human platelets. Blood 1998;92:1852-1858.
-
(1998)
Blood
, vol.92
, pp. 1852-1858
-
-
Oda, A.1
Ochs, H.D.2
Druker, B.J.3
Ozaki, K.4
Watanabe, C.5
Handa, M.6
Miyakawa, Y.7
Ikeda, Y.8
-
80
-
-
0037155856
-
Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases
-
Crosby D, Poole AW: Interaction of Bruton's tyrosine kinase and protein kinase Ctheta in platelets. Cross-talk between tyrosine and serine/threonine kinases. J Biol Chem 2002;277:9958-9965.
-
(2002)
J Biol Chem
, vol.277
, pp. 9958-9965
-
-
Crosby, D.1
Poole, A.W.2
-
81
-
-
0035002951
-
Bruton's tyrosine kinase associates with the actinbased cytoskeleton in activated platelets
-
Mukhopadhyay S, Ramars AS, Dash D: Bruton's tyrosine kinase associates with the actinbased cytoskeleton in activated platelets. J Cell Biochem 2001;81:659-665.
-
(2001)
J Cell Biochem
, vol.81
, pp. 659-665
-
-
Mukhopadhyay, S.1
Ramars, A.S.2
Dash, D.3
-
82
-
-
0035823269
-
Bruton's tyrosine kinase is a substrate of calpain in human platelets
-
Mukhopadhyay S, Ramars AS, Ochs HD, Dash D: Bruton's tyrosine kinase is a substrate of calpain in human platelets. FEBS Lett 2001;505:37-41.
-
(2001)
FEBS Lett
, vol.505
, pp. 37-41
-
-
Mukhopadhyay, S.1
Ramars, A.S.2
Ochs, H.D.3
Dash, D.4
-
83
-
-
0034938535
-
Bruton's tyrosine kinase is present in normal platelets and its absence identifies patients with X-linked agammaglobulinaemia and carrier females
-
Futatani T, Watanabe C, Baba Y, Tsukada S, Ochs HD: Bruton's tyrosine kinase is present in normal platelets and its absence identifies patients with X-linked agammaglobulinaemia and carrier females. Br J Haematol 2001;114:141-149.
-
(2001)
Br J Haematol
, vol.114
, pp. 141-149
-
-
Futatani, T.1
Watanabe, C.2
Baba, Y.3
Tsukada, S.4
Ochs, H.D.5
-
84
-
-
0035254644
-
Phosphatidylinositol 3-kinase-dependent translocation of phospholipase Cgamma2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation
-
Bobe R, Wilde JI, Maschberger P, Venkateswarlu K, Cullen PJ, Siess W, Watson SP: Phosphatidylinositol 3-kinase-dependent translocation of phospholipase Cgamma2 in mouse megakaryocytes is independent of Bruton tyrosine kinase translocation. Blood 2001;97:678-684.
-
(2001)
Blood
, vol.97
, pp. 678-684
-
-
Bobe, R.1
Wilde, J.I.2
Maschberger, P.3
Venkateswarlu, K.4
Cullen, P.J.5
Siess, W.6
Watson, S.P.7
-
85
-
-
0041737534
-
Murine GPVI stimulates weak integrin activation in PLCgamma2-/- platelets: Involvement of PLCgamma1 and PI3-kinase
-
Suzuki-Inoue K, Inoue O, Frampton J, Watson SP: Murine GPVI stimulates weak integrin activation in PLCgamma2-/- platelets: Involvement of PLCgamma1 and PI3-kinase. Blood 2003;102:1367-1373.
-
(2003)
Blood
, vol.102
, pp. 1367-1373
-
-
Suzuki-Inoue, K.1
Inoue, O.2
Frampton, J.3
Watson, S.P.4
-
86
-
-
0028880455
-
Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor
-
Wu H, Liu X, Jaenisch R, Lodish HF: Generation of committed erythroid BFU-E and CFU-E progenitors does not require erythropoietin or the erythropoietin receptor. Cell 1995;83:59-67.
-
(1995)
Cell
, vol.83
, pp. 59-67
-
-
Wu, H.1
Liu, X.2
Jaenisch, R.3
Lodish, H.F.4
-
87
-
-
18244432009
-
Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis
-
Neubauer H, Cumano A, Muller M, Wu H, Huffstadt U, Pfeffer K: Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis. Cell 1998;93:397-409.
-
(1998)
Cell
, vol.93
, pp. 397-409
-
-
Neubauer, H.1
Cumano, A.2
Muller, M.3
Wu, H.4
Huffstadt, U.5
Pfeffer, K.6
-
88
-
-
0025979427
-
Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant
-
Flanagan JG, Chan DC, Leder P: Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant. Cell 1991;64:1025-1035.
-
(1991)
Cell
, vol.64
, pp. 1025-1035
-
-
Flanagan, J.G.1
Chan, D.C.2
Leder, P.3
-
89
-
-
0029902069
-
High expression of the tec gene product in murine testicular germ cells and erythroblasts
-
Kazama A, Mano H, Morishita Y, Mori S: High expression of the tec gene product in murine testicular germ cells and erythroblasts. Pathol Int 1996;46:341-347.
-
(1996)
Pathol Int
, vol.46
, pp. 341-347
-
-
Kazama, A.1
Mano, H.2
Morishita, Y.3
Mori, S.4
-
90
-
-
0034669936
-
Stem cell factor induces phosphatidylinositol 3′-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells
-
van Dijk TB, van Den Akker E, Amelsvoort MP, Mano H, Lowenberg B, von Lindern M: Stem cell factor induces phosphatidylinositol 3′-kinase- dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells. Blood 2000;96:3406-3413.
-
(2000)
Blood
, vol.96
, pp. 3406-3413
-
-
Van Dijk, T.B.1
Van Den Akker, E.2
Amelsvoort, M.P.3
Mano, H.4
Lowenberg, B.5
Von Lindern, M.6
-
91
-
-
17544400277
-
An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells
-
Whyatt D, Lindeboom F, Karis A, Ferreira R, Milot E, Hendriks R, de Bruijn M, Langeveld A, Gribnau J, Grosveld F, Philipsen S: An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells. Nature 2000;406:519-524.
-
(2000)
Nature
, vol.406
, pp. 519-524
-
-
Whyatt, D.1
Lindeboom, F.2
Karis, A.3
Ferreira, R.4
Milot, E.5
Hendriks, R.6
De Bruijn, M.7
Langeveld, A.8
Gribnau, J.9
Grosveld, F.10
Philipsen, S.11
-
92
-
-
12144288611
-
Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors
-
Schmidt U, van den Akker E, Parren-van Amelsvoort M, Litos G, de Bruijn M, Gutiérrez L, Hendriks RW, Ellmeier W, Löwenberg B, Beug H, von Lindern M: Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against TRAIL in erythroid progenitors. J Exp Med 2004;199:785-795.
-
(2004)
J Exp Med
, vol.199
, pp. 785-795
-
-
Schmidt, U.1
Van Den Akker, E.2
Parren-Van Amelsvoort, M.3
Litos, G.4
De Bruijn, M.5
Gutiérrez, L.6
Hendriks, R.W.7
Ellmeier, W.8
Löwenberg, B.9
Beug, H.10
Von Lindern, M.11
-
93
-
-
0033555546
-
Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex
-
Vassilev A, Ozer Z, Navara C, Mahajan S, Uckun FM: Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex. J Biol Chem 1999;274:1646-1656.
-
(1999)
J Biol Chem
, vol.274
, pp. 1646-1656
-
-
Vassilev, A.1
Ozer, Z.2
Navara, C.3
Mahajan, S.4
Uckun, F.M.5
-
94
-
-
0036838086
-
Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: Role in endothelial cell migration and angiogenesis
-
Pan S, An P, Zhang R, He X, Yin G, Min W: Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: Role in endothelial cell migration and angiogenesis. Mol Cell Biol 2002;22:7512-7513.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7512-7513
-
-
Pan, S.1
An, P.2
Zhang, R.3
He, X.4
Yin, G.5
Min, W.6
-
95
-
-
0037265240
-
Alternative activation of macrophages
-
Gordon S: Alternative activation of macrophages. Nat Rev Immunol 2003;3:23-35.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 23-35
-
-
Gordon, S.1
-
96
-
-
0033046220
-
Mechanisms of phagocytosis in macrophages
-
Aderem A, Underhill DM: Mechanisms of phagocytosis in macrophages. Annu Rev Immunol 1999;17:593-623.
-
(1999)
Annu Rev Immunol
, vol.17
, pp. 593-623
-
-
Aderem, A.1
Underhill, D.M.2
-
97
-
-
0034255209
-
Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens
-
Nathan C, Shiloh MU: Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens. Proc Natl Acad Sci USA 2000;97:8841-8848.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8841-8848
-
-
Nathan, C.1
Shiloh, M.U.2
-
98
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I, Liu MY, Van Huffel C, Du X, Birdwell D, Alejos E, Silva M, Galanos C, Freudenberg M, Ricciardi-Castagnoli P, Layton B, Beutler B: Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene. Science 1998;282:2085-2088.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
Liu, M.Y.4
Van Huffel, C.5
Du, X.6
Birdwell, D.7
Alejos, E.8
Silva, M.9
Galanos, C.10
Freudenberg, M.11
Ricciardi-Castagnoli, P.12
Layton, B.13
Beutler, B.14
-
99
-
-
0035903288
-
Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
-
Kadowaki N, Ho S, Antonenko S, Malefyt RW, Kastelein RA, Bazan F, Liu YJ: Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med 2001;194:863-869.
-
(2001)
J Exp Med
, vol.194
, pp. 863-869
-
-
Kadowaki, N.1
Ho, S.2
Antonenko, S.3
Malefyt, R.W.4
Kastelein, R.A.5
Bazan, F.6
Liu, Y.J.7
-
100
-
-
0037492123
-
Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4
-
Jefferies CA, Doyle S, Brunner C, Dunne A, Brint E, Wietek C, Walch E, Wirth T, O'Neill LA: Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4. J Biol Chem 2003;278:26258-26264.
-
(2003)
J Biol Chem
, vol.278
, pp. 26258-26264
-
-
Jefferies, C.A.1
Doyle, S.2
Brunner, C.3
Dunne, A.4
Brint, E.5
Wietek, C.6
Walch, E.7
Wirth, T.8
O'Neill, L.A.9
-
101
-
-
0035817925
-
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
-
Fitzgerald KA, Palsson-McDermott EM, Bowie AG, Jefferies CA, Mansell AS, Brady G, Brint E, Dunne A, Gray P, Harte MT, McMurray D, Smith DE, Sims JE, Bird TA, O'Neill LA: Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction. Nature 2001;413:78-83.
-
(2001)
Nature
, vol.413
, pp. 78-83
-
-
Fitzgerald, K.A.1
Palsson-McDermott, E.M.2
Bowie, A.G.3
Jefferies, C.A.4
Mansell, A.S.5
Brady, G.6
Brint, E.7
Dunne, A.8
Gray, P.9
Harte, M.T.10
McMurray, D.11
Smith, D.E.12
Sims, J.E.13
Bird, T.A.14
O'Neill, L.A.15
-
102
-
-
0035524488
-
Toll-like receptors and innate immunity
-
Medzhitov R: Toll-like receptors and innate immunity. Nat Rev Immunol 2001;1:135-145.
-
(2001)
Nat Rev Immunol
, vol.1
, pp. 135-145
-
-
Medzhitov, R.1
-
103
-
-
0037087438
-
Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial than the cytokine balance of T cell responses for microfilarial clearance
-
Mukhopadhyay S, Mohanty M, Mangla A, George A, Bal V, Rath S, Ravindran B: Macrophage effector functions controlled by Bruton's tyrosine kinase are more crucial than the cytokine balance of T cell responses for microfilarial clearance. J Immunol 2002;168:2914-2921.
-
(2002)
J Immunol
, vol.168
, pp. 2914-2921
-
-
Mukhopadhyay, S.1
Mohanty, M.2
Mangla, A.3
George, A.4
Bal, V.5
Rath, S.6
Ravindran, B.7
-
104
-
-
0033775754
-
NF-kappa B regulates the LPS-induced expression of interleukin 12 p40 in murine peritoneal macrophages: Roles of PKC, PKA, ERK, p38 MAPK, and proteasome
-
Zhang JS, Feng WG, Li CL, Wang XY, Chang ZL: NF-kappa B regulates the LPS-induced expression of interleukin 12 p40 in murine peritoneal macrophages: Roles of PKC, PKA, ERK, p38 MAPK, and proteasome. Cell Immunol 2000;204:38-45.
-
(2000)
Cell Immunol
, vol.204
, pp. 38-45
-
-
Zhang, J.S.1
Feng, W.G.2
Li, C.L.3
Wang, X.Y.4
Chang, Z.L.5
-
105
-
-
0033515450
-
Rational design and synthesis of a novel antileukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-betahydroxy-beta-methyl-N- (2, 5-dibromophenyl) propenamide]
-
Mahajan S, Ghosh S, Sudbeck EA, Zheng Y, Downs S, Hupke M, Uckun FM: Rational design and synthesis of a novel antileukemic agent targeting Bruton's tyrosine kinase (BTK), LFM-A13 [alpha-cyano-betahydroxy-beta-methyl-N-(2, 5-dibromophenyl) propenamide]. J Biol Chem 1999;274:9587-9599.
-
(1999)
J Biol Chem
, vol.274
, pp. 9587-9599
-
-
Mahajan, S.1
Ghosh, S.2
Sudbeck, E.A.3
Zheng, Y.4
Downs, S.5
Hupke, M.6
Uckun, F.M.7
-
106
-
-
0034657307
-
Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement
-
Petro JB, Rahman SM, Ballard DW, Khan WN: Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement. J Exp Med 2000;191:1745-1754.
-
(2000)
J Exp Med
, vol.191
, pp. 1745-1754
-
-
Petro, J.B.1
Rahman, S.M.2
Ballard, D.W.3
Khan, W.N.4
-
107
-
-
0035910580
-
Phospholipase C-gamma 2 couples Bruton's tyrosine kinase to the NF-kappaB signaling pathway in B lymphocytes
-
Petro JB, Khan WN: Phospholipase C-gamma 2 couples Bruton's tyrosine kinase to the NF-kappaB signaling pathway in B lymphocytes. J Biol Chem 2001;276:1715-1719.
-
(2001)
J Biol Chem
, vol.276
, pp. 1715-1719
-
-
Petro, J.B.1
Khan, W.N.2
-
108
-
-
0037124307
-
Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha
-
Saijo K, Mecklenbrauker I, Santana A, Leitger M, Schmedt C, Tarakhovsky A: Protein kinase C beta controls nuclear factor kappaB activation in B cells through selective regulation of the IkappaB kinase alpha. J Exp Med 2002;195:1647-1652.
-
(2002)
J Exp Med
, vol.195
, pp. 1647-1652
-
-
Saijo, K.1
Mecklenbrauker, I.2
Santana, A.3
Leitger, M.4
Schmedt, C.5
Tarakhovsky, A.6
-
109
-
-
0242557486
-
Defective Fc-, CR1- And CR3-mediated monocyte phagocytosis and chemotaxis in common variable immunodeficiency and X-linked agammaglobulinemia patients
-
Amoras AL, Kanegane H, Miyawaki T, Vilela MM: Defective Fc-, CR1- and CR3-mediated monocyte phagocytosis and chemotaxis in common variable immunodeficiency and X-linked agammaglobulinemia patients. J Investig Allergol Clin Immunol 2003;13:181-188.
-
(2003)
J Investig Allergol Clin Immunol
, vol.13
, pp. 181-188
-
-
Amoras, A.L.1
Kanegane, H.2
Miyawaki, T.3
Vilela, M.M.4
-
110
-
-
0033567049
-
Bruton's tyrosine kinase deficiency in macrophages inhibits nitric oxide generation leading to enhancement of IL-12 induction
-
Mukhopadhyay S, George A, Bal V, Ravindran B, Rath S: Bruton's tyrosine kinase deficiency in macrophages inhibits nitric oxide generation leading to enhancement of IL-12 induction. J Immunol 1999;163:1786-1792.
-
(1999)
J Immunol
, vol.163
, pp. 1786-1792
-
-
Mukhopadhyay, S.1
George, A.2
Bal, V.3
Ravindran, B.4
Rath, S.5
-
111
-
-
0033565721
-
Delayed clearance of filarial infection and enhanced Th1 immunity due to modulation of macrophage APC functions in xid mice
-
Mukhopadhyay S, Sahoo PK, George A, Bal V, Rath S, Ravindran B: Delayed clearance of filarial infection and enhanced Th1 immunity due to modulation of macrophage APC functions in xid mice. J Immunol 1999;163:875-883.
-
(1999)
J Immunol
, vol.163
, pp. 875-883
-
-
Mukhopadhyay, S.1
Sahoo, P.K.2
George, A.3
Bal, V.4
Rath, S.5
Ravindran, B.6
-
112
-
-
0036076652
-
Chemotactic signaling pathways in neutrophils: From receptor to actin assembly
-
Cicchetti G, Allen PG, Glogauer M: Chemotactic signaling pathways in neutrophils: From receptor to actin assembly. Crit Rev Oral Biol Med 2002;13:220-228.
-
(2002)
Crit Rev Oral Biol Med
, vol.13
, pp. 220-228
-
-
Cicchetti, G.1
Allen, P.G.2
Glogauer, M.3
-
113
-
-
0035043710
-
The neutrophil: Function and regulation in innate and humoral immunity
-
Burg ND, Pillinger MH: The neutrophil: Function and regulation in innate and humoral immunity. Clin Immunol 2001;99:7-17.
-
(2001)
Clin Immunol
, vol.99
, pp. 7-17
-
-
Burg, N.D.1
Pillinger, M.H.2
-
114
-
-
0038221378
-
Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. II. Effects of LFM-A13, a specific Btk inhibitor
-
Gilbert C, Levasseur S, Desaulniers P, Dusseault AA, Thibault N, Bourgoin SG, Naccache PH: Chemotactic factor-induced recruitment and activation of Tec family kinases in human neutrophils. II. Effects of LFM-A13, a specific Btk inhibitor. J Immunol 2003;170:5235-5243.
-
(2003)
J Immunol
, vol.170
, pp. 5235-5243
-
-
Gilbert, C.1
Levasseur, S.2
Desaulniers, P.3
Dusseault, A.A.4
Thibault, N.5
Bourgoin, S.G.6
Naccache, P.H.7
-
115
-
-
0345138995
-
BTK regulates PtdIns-4,5-P2 synthesis: Importance for calcium signaling and PI3K activity
-
Saito K, Tolias KF, Saci A, Koon HB, Humphries LA, Scharenberg A, Rawlings DJ, Kinet JP, Carpenter CL: BTK regulates PtdIns-4,5-P2 synthesis: Importance for calcium signaling and PI3K activity. Immunity 2003;19:669-678.
-
(2003)
Immunity
, vol.19
, pp. 669-678
-
-
Saito, K.1
Tolias, K.F.2
Saci, A.3
Koon, H.B.4
Humphries, L.A.5
Scharenberg, A.6
Rawlings, D.J.7
Kinet, J.P.8
Carpenter, C.L.9
-
116
-
-
0034041033
-
Immunobiology of dendritic cells
-
Banchereau J, Briere F, Caux C, Davoust J, Lebecque S, Liu YJ, Pulendran B, Palucka K: Immunobiology of dendritic cells. Annu Rev Immunol 2000;18:767-811.
-
(2000)
Annu Rev Immunol
, vol.18
, pp. 767-811
-
-
Banchereau, J.1
Briere, F.2
Caux, C.3
Davoust, J.4
Lebecque, S.5
Liu, Y.J.6
Pulendran, B.7
Palucka, K.8
-
117
-
-
17944377368
-
PKCbeta modulates antigen receptor signaling via regulation of Btk membrane localization
-
Kang SW, Wahl MI, Chu J, Kitaura J, Kawakami Y, Kato RM, Tabuchi R, Tarakhovsky A, Kawakami T, Turck CW, Witte ON, Rawlings DJ: PKCbeta modulates antigen receptor signaling via regulation of Btk membrane localization. EMBO J 2001;20:5692-5702.
-
(2001)
EMBO J
, vol.20
, pp. 5692-5702
-
-
Kang, S.W.1
Wahl, M.I.2
Chu, J.3
Kitaura, J.4
Kawakami, Y.5
Kato, R.M.6
Tabuchi, R.7
Tarakhovsky, A.8
Kawakami, T.9
Turck, C.W.10
Witte, O.N.11
Rawlings, D.J.12
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