A novel function for the Tec family tyrosine kinase Itk in activation of β1 integrins by the T-cell receptor

EMBO Journal

Volumn 20, Issue 6, 2001, Pages 1232-1244

  Woods, Melody L ^a   Kivens, Wendy J ^a   Adelsman, Margaret A ^a   Qiu, Yun ^a   August, Avery ^b   Shimizu, Yoji ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Integrin; Itk; Lck; Phosphatidylinositol 3 kinase; T lymphocyte

Indexed keywords

ACTIN; BETA1 INTEGRIN; CD3 ANTIGEN; CD4 ANTIGEN; GLYCOSPHINGOLIPID; PHOSPHATIDYLINOSITOL 3 KINASE; PLECKSTRIN; PROTEIN TYROSINE KINASE; T LYMPHOCYTE RECEPTOR;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; LEUKOCYTE ADHERENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; SEQUENCE HOMOLOGY; T LYMPHOCYTE ACTIVATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACTINS; ANTIGENS, CD29; ANTIGENS, CD3; CELL ADHESION; CELL COMPARTMENTATION; HUMANS; JURKAT CELLS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHORIC MONOESTER HYDROLASES; PROTEIN TRANSPORT; PROTEIN-TYROSINE KINASES; PTEN PHOSPHOHYDROLASE; RECEPTORS, ANTIGEN, T-CELL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

EID: 0035868761     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.6.1232     Document Type: Article

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