Delayed clearance of filarial infection and enhanced Th1 immunity due to modulation of macrophage APC functions in xid mice

Journal of Immunology

Volumn 163, Issue 2, 1999, Pages 875-883

  Mukhopadhyay, Sangita ^a,b   Sahoo, Prakash Kumar ^b   George, Anna ^a   Bal, Vineeta ^a   Rath, Satyajit ^a   Ravindran, Bala ^b  

^a NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

^b REGIONAL MEDICAL RESEARCH CENTRE ICMR   (India)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 5;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN PRESENTING CELL; ARTICLE; CONTROLLED STUDY; FILARIASIS; IMMUNOREGULATION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PARASITE IMMUNITY; PRIORITY JOURNAL; SETARIA; T LYMPHOCYTE ACTIVATION;

ANIMALS; ANTIBODIES, HELMINTH; ANTIGEN PRESENTATION; ANTIGEN-PRESENTING CELLS; FEMALE; IMMUNOLOGIC DEFICIENCY SYNDROMES; INTERFERON TYPE II; LYMPHOCYTE ACTIVATION; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED CBA; MICE, MUTANT STRAINS; MICROFILARIA; PROTEIN-TYROSINE KINASES; SERUM ALBUMIN, BOVINE; SETARIASIS; SPECIES SPECIFICITY; TH1 CELLS; TIME FACTORS;

EID: 0033565721     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (74)

1. Kim, J., A. Woods, E. Becker-Dunn, and K. Bottomly. 1985. Distinct functional phenotypes of cloned Ia-restricted helper T cells. J. Exp. Med. 162:188.
2. Mosmann, T. R., H. Cherwinski, M. W. Bond, M. A. Giedlin, and R. L. Coffman. 1986. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136:2348.
3. Paul, W. E., and R. A. Seder. 1994. Lymphocyte response and cytokines. Cell 76:241.
4. Flesch, I. E. A., and S. H. Kaufmann. 1987. Mycobacterial growth inhibition by interferon-γ-activated bone marrow macrophages and differential susceptibility among strains of Mycobacterium tuberculosis. J. Immunol. 138:4408.
5. Stout, R., and K. Bottomly. 1989. Antigen-specific activation of effector macrophages by IFN-γ producing (Th1) T cell clones: failure of IL-4 producing (Th2) T cell clones to activate effector function in macrophages. J. Immunol. 142:760.
6. Swain, S. L., A. D. Weinberg, M. English, and G. Huston. 1990. IL-4 directs the development of Th2 like helper effectors. J. Immunol. 145:3796.
7. de Waal Malefyt, R., H. Yssel, M. G. Roncarolo, H. Spits, and J. E. de Vries. 1992. Interleukin-10. Curr. Opin. Immunol. 4:314.
8. Sher, A., and R. L. Coffman. 1992. Regulation of immunity to parasites by T cells and T cell-derived cytokines. Annu. Rev. Immunol. 10:385.
9. Urban, J. F., K. B. Madden, A. Svetic, A. Cheever, P. P. Trotta, W. C. Gause, I. M. Katona, and C. R. Finkelman. 1992. The importance of Th2 cytokines in protective immunity to nematodes. Immunol. Rev. 127:205.
10. King, C. L., S. Mahanty, V. Kumaraswami, J. S. Abrams, J. Regunathan, K. Jayaraman, E. A. Ottesen, and T. B. Nutman. 1993. Cytokine control of parasite-specific anergy in human lymphatic filariasis: preferential induction of a regulatory T helper type 2 lymphocyte subset. J. Clin. Invest. 92:1667.
11. Mosmann, T. R., and S. Sad. 1996. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol. Today 17:138.
12. Ravichandran, M., S. Mahanty, V. Kumaraswami, T. B. Nutman, and K. Jayaraman. 1997. Elevated IL-10 mRNA expression and downregulation of Th1-type cytokines in microfilaraemic individuals with Wuchereria bancrofti infection. Parasite Immunol. 19:69.
13. + cell dependent and cyclosporine A resistant. J. Helminthol. 61:19.
14. Bancroft, A. J., R. K. Grencis, K. J. Else, and E. Devany. 1993. Cytokine production in BALB/C mice immunized with radiation attenuated third stage larvae of the nematode, Brugia pahangi. J. Immunol. 150:1395.
15. Baldwin, C. I., F. de Medeiros, and D. A. Denham. 1993. IgE responses in cats infected with Brugia pahangi. Parasite Immunol. 15:291.
16. Pearlman, E., W. K. Kroeze, F. E. Hazlett, S. S. A. Chen, S. D. Mawhorter, W. H. Boom, and J. W. Kazura. 1993. Brugia malayi: acquired resistance to microfilariae in BALB/c mice correlates with local Th2 responses. Exp. Parasitol. 76:200.
17. Pfeiffer, C., K. Stein, S. Southwood, A. Sette, and K. Bottomly. 1995. Altered peptide ligands can control CD4 T lymphocyte differentiation in vivo. J. Exp. Med. 182:1569.
18. Windhagen, A., C. Scholz, P. Hollsberg, H. Fukaura, A. Sette, and D. A. Hafler. 1995. Modulation of cytokine patterns of human autoreactive T cell clones by a single amino acid substitution of their peptide ligand. Immunity 2:373.
19. Kumar, V., V. Bhardwaj, L. Soares, J. Alexander, A. Sette, and E. Sercarz. 1995. Major histocompatibility complex binding affinity of an antigenic determinant is crucial for the differential secretion of interleukin 4/5 or interferon γ by T cells. Proc. Natl. Acad. Sci. USA 92:9510.
20. Chaturvedi, P., Q. Yu, S. Southwood, A. Sette, and B. Singh. 1996. Peptide analogs with different affinities for MHC alter the cytokine profile of T helper cells. Int. Immunol. 8:745.
21. Singh, N., S. Bhatia, R. Abraham, S. K. Basu, A. George, V. Bal, and S. Rath. 1998. Modulation of T cell cytokine profiles and peptide-MHC complex availability in vivo by delivery to scavenger receptors via antigen-maleylation. J. Immunol. 160:4869.
22. D'Andrea, A., M. Aste-Amezaga, X. Ma, M. Kubin, and G. Trinchieri. 1993. Interleukin 10 (IL-10) inhibits human lymphocyte interferon γ production by suppressing natural killer cell stimulatory factor/IL-12 synthesis in accessory cells. J. Exp. Med. 178:1041.
23. + T cells. J. Exp. Med. 185:461.
24. + T cells through IL-12 produced by Listeria-induced macrophages. Science 260:547.
25. + T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ dependent. Int. Immunol. 5:1119.
26. Magram, J., S. E. Connaughton, R. R. Warrier, D. M. Carjaval, C. Y. Wu, J. Ferrante, C. Stewart, U. Sarmiento, D. A. Faherty, and M. K. Gately. 1996. IL-12-deficient mice are defective in IFN-γ production and type 1 cytokine responses. Immunity 4:471.
27. de Waal Malefyt, R., J. Haanen, H. Spits, M. G. Roncarolo, A. te Velde, C. Figdor, K. Johnson, R. Kastelein, H. Yessel, and J. E. de Vries. 1991. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J. Exp. Med. 174:915.
28. Sicher, S. C., G. W. Chung, M. A. Vazquez, and C. Y. Lu. 1995. Augmentation or inhibition of IFN-γ-induced MHC class II expression by lipopolysaccharides: the roles of TNF-alpha and nitric oxide and the importance of the sequence of signaling. J. Immunol. 155:5826.
29. Heise, M. T., J. L. Pollock, A. O'Guin, M. L. Barkon, S. Bromly, and H. V. Virgin. 1998. Murine cytomegalovirus infection inhibits IFN-γ-induced MHC class II expression on macrophages: the role of type I interferon. Virology 241:331.
30. Hauschildt, S., and B. Kleine. 1995. Bacterial stimulators of macrophages. Int. Rev. Cytol. 161:263.
31. Aarden, L. A., E. R. de Groot, O. L. Schaap, and P. M. Lansdorp. 1987. Production of hybridoma growth factor by monocytes. Eur. J. Immunol. 17:1411.
32. D'Andrea, A., M. Rengarayu, N. M. Valginte, J. Chemini, M. Kibin, M. Aste, S. H. Chan, M. Kobayashi, D. Young, and E. Nichbarg. 1992. Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells. J. Exp. Med. 176:1387.
33. Trinchieri, G. 1997. Cytokines acting on or secreted by macrophages during intracellular infection (IL-10, IL-12, IFN-γ). Curr. Opin. Immunol. 9:17.
34. van Snick, J. 1990. Interleukin-6: an overview. Annu. Rev. Immunol. 8:253.
35. Akira, S., T. Taga, and T. Kishimoto. 1993. Interleukin-6 in biology and medicine. Adv. Immunol. 54:1.
36. Ladel, C. H., G. Szalay, D. Riedel, and S. H. Kaufmann. 1997. Interleukin-12 secretion by Mycobacterium tuberculosis-infected macrophages. Infect. Immun. 65:1936.
37. Probst, P., Y. A. Skeiky, M. Steeves, A. Gervassi, K. H. Grabstein, and S. G. Reed. 1997. A Leishmania protein that modulates interleukin (IL)-12, IL-10 and tumor necrosis factor-α production and expression of B7-1 in human monocyte-derived antigen-presenting cells. Eur. J. Immunol. 27:2634.
38. van Heyningen, T. K. 1997. IL-6 produced by macrophages infected with Mycobacterium species supresses T-cell response. J. Immunol. 158:330.
39. Kuchroo, V. K., M. P. Das, J. A. Brown, A. M. Ranger, S. S. Zamvil, R. A. Sobel, H. L. Weiner, N. Nabavi, and L. H. Glimcher. 1995. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune therapy. Cell 80:707.
40. Gupta, S., H. Vohra, B. Saha, C. K. Nain, and N. K. Ganguly. 1996. Macrophage-T cell interaction in murine salmonellosis: selective down-regulation of ICAM-1 and B7 molecules in infected macrophages and its probable role in cell-mediated immunity. Eur. J. Immunol. 26:563.
41. Frosch, S., D. Kuntzlin, and B. Fleischer. 1997. Infection with Trypanosoma cruzi selectively upregulates B7-2 molecules on macrophages and enhances their costimulatory activity. Infect. Immun. 65:971.
42. Hayes, M. P., J. Wang, and M. A. Norcross. 1995. Regulation of interleukin-12 expression in human monocytes: selective priming by IFN-γ of LPS-inducible p35 and p40 genes. Blood 86:646.
43. Murphy, T. L., M. G. Cleveland, P. Kulsesza, J. Magram, and K. M. Murphy. 1995. Regulation of interleukin 12 p40 expression through NF-κB half site. Mol. Cell. Biol. 15:5258.
44. de Weers, M., M. C. M. Verschuren, M. E. Kraakman, R. G. J. Mensink, R. K. B. Schuurman, J. J. M. van Dongen, and R. W. Hendriks. 1993. The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages. Eur. J. Immunol. 23:3109.
45. Smith, C. I. E., B. Baskin, B. P Humire-Greiff, J. Zhou, P. G. Olsson, H. S. Maniar, P. Kjellen, J. D. Lambris, B. Christensson, L. Hammarstrom, et al. 1994. Expression of Bruton's agammaglobulinemia tyrosine kinase gene, Btk, is selectively down-regulated in T lymphocytes and plasma cells. J. Immunol. 152: 557.
46. Khan, W. N., F. W. Alt, R. M. Gerstein, B. A. Malynn, I. Larsson., G. Rathbun, L. Davidson, S. Mueller, A. B. Kantor, L. A. Herzenberg, et al. 1995. Defective B cell development and function in Btk-deficient mice. Immunity 3:283.
47. Desiderio, S. 1997. Role of Btk in B cell development and signaling. Curr. Opin. Immunol. 9:534.
48. Mukhopadhyay, S., A. P. Dash, and B. Ravindran. 1996. Setaria digitata in Mastomys coucha: an animal model for chemotherapeutic and immunobiological studies. Parasitology 113:323.
49. Haberland, M. E., and A. M. Fogelman. 1985. Scavenger receptor mediated recognition of maleyl bovine plasma albumin and the demaleylated protein in human monocyte macrophages. Proc. Natl. Acad. Sci. USA 82:2693.
50. Abraham, R., N. Singh, A. Mukhopadhyay, S. K. Basu, V. Bal, and S. Rath. 1995. Modulation of immunogenicity and antigenicity of proteins by maleylation to target scavenger receptors on macrophages. J. Immunol. 154:1.
51. Habeeb, A. F. 1966. Determination of free amino groups in proteins by trinitrobenzenesulfonic acid. Anal. Biochem. 14:328.
52. Taswell, C. 1981. Limiting dilution assays for the determination of immunocompetent cell frequencies. J. Immunol. 126:1614.
53. Thompson, J. P., R. B. Crandall, C. A. Crandall, and J. T. Neilson. 1981. Microfilaremia and antibody responses in CBA/H and CBA/N following injection of microfilariae of Brugia malayi. J. Parasitol. 67:728.
54. Al-Qaoud, K. M., B. Fleischer, and A. Hoerauf. 1998. The Xid defect imparts susceptibility to experimental murine filariasis: association with a lack of antibody and IL-10 production by B cells in response to phosphorylcholine. Int. Immunol. 10:17.
55. Snapper, C. M., and W. E. Paul. 1987. Interferon-γ and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 236:944.
56. Coffman, R. L., B. W. P. Seymour, D. A. Lebman, D. D. Hiraki, J. Christiansen, B. Schrader, H. M. Cherwinski, H. F. J. Savelkoul, F. D. Finkelman, M. W. Bond, and T. R. Mosmann. 1988. The role of helper T cell products in mouse B cell differentiation and isotype regulation. Immunol. Rev. 102:5.
57. Snapper, C. M., C. Peschel, C., and W. E. Paul. 1988. IFN-γ stimulates IgGZa secretion by murine B cells stimulated with bacterial lipopolysaccharide. J. Immunol. 140:2121.
58. Huber, B., and F. Melchers. 1979. Frequencies of mitogen reactive B cells in the mouse: lipopolysaccharide, lipoprotein and Nocardia mitogen reactive B cells in CBA/N mice. Eur. J. Immunol. 9:827.
59. Ravindran, B., P. K. Sahoo, M. Mohanty, S. Mukhopadhyay, and A. P. Dash. 1999. Increased susceptibility of mice with XID mutation to Brugia malayi infection. Med. Sci. Res. 27:135.
60. + T cells in controlling larval development. Infect. Immun. 65:2457.
61. + T cells correlate with T-cell unresponsiveness in rhesus monkeys chronically infected with Brugia malayi. Exp. Parasitol. 90:77.
62. Hayakawa, K., R. R. Hardy, and L. A. Herzenberg. 1986. Peritoneal Ly-1 B cells: genetic control, autoantibody production, increased light chain expression. Eur. J. Immunol. 16:450.
63. Kuchroo, V.K., M. P. Das, J. A. Brown, A. M. Ranger, S. S. Zamvil, R. A. Sobel, H. L. Weiner, N. Nabavi, and L. H. Glimcher 1995. B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: Application to autoimmune disease therapy. Cell 80 :707.
64. Soong, L., J. C. Xu, I. S. Grewal, P. Kima, J. Sun, B. J. Longley, N. H. Ruddle, D. McMahon-Pratt, and R. A. Flavell. 1996. Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. Immunity 4:263.
65. Liu, Y., R. H. Wenger, M. Zhao, and P. Nielsen. 1997. Distinct costimulatory molecules are required for the induction of effector and memory cytotoxic T lymphocytes. J. Exp. Med. 185:251.
66. Goldstein, M. D., M. A. Debenedette, D. Hollenbaugh, and T. H. Watts. 1996. Induction of costimulatory molecules B7-1 and B7-2 in murine B cells, the CBA/N mouse reveals a role for Bruton's tyrosine kinase in CD40-mediated B7 induction. Mol. Immunol. 33:541.
67. Minoprio, P., A. Coutinho, S. Spinella, and M. Hontebeyrie-Joskowicz. 1991. Xid immunodeficiency imparts increased parasite clearance and resistance to pathology in experimental Chagas' disease. Int. Immunol. 3:427.
68. Hoerauf, A., W. Solbach, M. Lohoff, and M. Rollinghoff. 1994. The XID defect determines an improved clinical course of murine leishmaniasis in susceptible mice. Int. Immunol. 6:1117.
69. Zhao, Y. X., A. Abdelnour, R. Holmdahl, and A. Tarkowski. 1995. Mice with the Xid B cell defect are less susceptible to developing Staphylococcus aureus-induced arthritis. J. Immunol. 155:2067.
70. Aoki, Y., K. J. Isselbacher, B. J. Cherayil, and S. Pillai. 1994. Tyrosine phosphorylatiion of Btk and Fyn Src homology 2 domain-binding proteins occurs in response to antigen-receptor ligation in B cells and constilulively in pre-B cells. Proc. Natl. Acad. Sci. USA 91:4204.
71. Saouf, S. J., S. Mahajan, B. R. Rowley, S. A. Kut, J. Fargnoli, A. L. Burkardt, S. Tsukada, O. N. Witte, and J. B. Bolen. 1994. Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell receptor surface engagement. Proc. Natl. acad. Sci. USA 91:9524.
72. Rawlings, D. J., A. M. Scharenberg, H. Park, M. I. Wahl, S. Lin, R. M. Kato, A. C. Fluckiger, O. N. Witte, J. P. Kinet. 1996. Activation of BTK by a phosphorylation mechanism initiated by SRC family kinases. Science 271:822.
73. Kawakami, Y., T. Miura, R. Bissonnette, D. Hata, W. N. Khan, T. Kitamura, M. Maeda-Yamamoto, S. E. Hartman, L. Yao, F. W. Alt, and T. Kawakami. 1997. Bruton's tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity. Proc. Natl. Acad. Sci. USA 94:3938.
74. Hata, D., Y. Kawakami, N. Inagaki, C. S. Lantz, T. Kitamura, W. N. Khan, M. Maeda-Yamamoto, T. Miura, W. Han, S. E. Hartman, et al. 1998. Involvement of Bruton's tyrosine kinase in Fc∈RI-dependent mast cell degranulation and cytokine production. J. Exp. Med. 187:1235.