An intrinsic but cell-nonautonomous defect in GATA-1-overexpressing mouse erythroid cells

Nature

Volumn 406, Issue 6795, 2000, Pages 519-524

  Whyatt, David ^a   Lindeboom, Fokke ^b   Karls, Alar ^b   Farreira, Rita ^b   Milot, Eric ^b   Hendriks, Rudi ^b   De Bruijn, Marella ^b   Langeveld, An ^b   Gribnau, Joost ^b   Grosveld, Frank ^b   Philipsen, Sjaak ^b  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR GATA 1;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; ERYTHROID CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANEMIA; ANIMALS; ANIMALS, GENETICALLY MODIFIED; APOPTOSIS; CHIMERA; CROSSES, GENETIC; DNA-BINDING PROTEINS; DOSAGE COMPENSATION, GENETIC; ERYTHROBLASTS; ERYTHROID PROGENITOR CELLS; ERYTHROID-SPECIFIC DNA-BINDING FACTORS; ERYTHROPOIESIS; FEMALE; GATA1 TRANSCRIPTION FACTOR; MALE; MICE; MICE, INBRED C57BL; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; X CHROMOSOME;

ANIMALIA; RODENTIA;

EID: 17544400277     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/35020086     Document Type: Article

References (30)

1. Pevny, L. et al. Erythroid differentiation in chimaeric mice blocked by a targeted mutation in the gene for transcription factor GATA-1. Nature 349, 257-260 (1991).
2. Weiss, M. J., Keller, G. & Orkin, S. H. Novel insights into erythroid development revealed through in vitro differentiation of GATA-1 embryonic stem cells. Genes Dev. 8, 1184-1197 (1994).
3. Rossant, J. & Spence, A. Chimera and mosaics in mouse mutant analysis. Trends Genet. 14, 358-363 (1998).
4. Weiss, M. J. & Orkin, S. H. Transcription factor GATA-1 permits survival and maturation of erythroid precursors by preventing apoptosis. Proc. Natl Acad. Sci. USA 92, 9623-9617 (1995).
5. Takahashi, S. et al. Role of GATA-1 in proliferation and differentiation of definitive erythroid and megakaryocytic cells in vivo. Blood 92, 434-442 (1998).
6. Whyatt, D. J. et al. The level of the tissue-specific factor GATA-1 affects the cell-cycle machinery. Genes Fund 1, 11-24 (1997).
7. Kuroda, M. I. & Meller, V. H. Transient Xist-ence. Cell 91, 9-11 (1997).
8. Fujiwara, Y., Browne, C. P., Cunniff, K., Goff, S. C. & Orkin, S. H. Arrested development of embryonic red cell precursors in mouse embryos lacking transcription factor GATA-1. Proc. Natl Acad. Sci. USA 93, 12355-12358 (1996).
9. Tsai, F.-Y., Browne, C. P. & Orkin, S. H. Knock-in mutation of transcription factor GATA-3 into the GATA-1 locus: partial rescue of GATA-1 loss of function in erythroid cells. Dev. Biol. 196, 218-227 (1998).
10. Panning, B., Dausman, J. & Jaenisch, R. X chromosome inactivation is mediated by Xist RNA stabilization. Cell 90, 907-916 (1997).
11. Sheardown, S. A. et al. Stabilization of Xist RNA mediates initiation of X chromosome inactivation. Cell 91, 99-107 (1997).
12. Hendriks, R. W. et al. Inactivation of Btk by insertion by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage. EMBO J. 15, 4862-4872 (1996).
13. Cormack, D. Time-lapse characterization of erythrocytic colony-forming cells in plasma cultures. Exp. Hematol. 4, 319-327 (1976).
14. Sawada, K., Krantz, S. B., Dessypris, E N. Koury, S. T. & Sawyer, S. T. Human colony-forming units-erythroid do not require acessory cells but do require direct interaction with insulin-like growth factor 1 and/or insulin for erythroid development. J. Clin. Invest. 83, 1701-1709 (1989).
15. Apfeld, I. & Kenyon, C. Cell nonautonomy of C. elegans daf-2 function in the regulation of diapause and life span. Cell 95, 199-210 (1998).
16. Dubart, A., Romeo, P. H., Vainchenker, W. & Dumenil, D. Constitutive expression of GATA-1 interferes with the cell-cycle regulation. Blood 87, 3711-3721 (1996).
17. Briegel, K, et al. Regulation and function of transcription factor GATA-1 during red blood cell differentiation. Development 122, 3839-3850 (1996).
18. Bessis, M., Lessin, L. S. & Beutler, E. in Hematology (eds Williams, W. J., Beutler, E., Erslev, A. J. & Lichtman, M. A.) 257-279 (McGraw-Hill, New York, 1983).
19. Bernard, J. The erythroblastic island: past and future. Blood Cells 17, 5-14 (1991).
20. De Maria, R. et al. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature 401, 489-493 (1999).
21. Williams, B. O. et al. Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences. EMBO J. 13, 4251-4259 (1994).
22. Maandag, E. C. et al. Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice. EMBO J. 13, 4260-4268 (1994).
23. Hu, N., Gulley, M. L., Kung, J. T. & Lee, E. Y.-H. Retinoblastoma gene deficiency has mitogenic but not tumorigenic effects on erythropoiesis. Cancer Res. 57, 4123-4129 (1997).
24. Elefanty, A. G., Antoniou, M., Custodio, N., Carmo-Fonseca, M. & Grosveld, F. G. GATA transcription factors associate with a novel class of nuclear bodies in erythroblasts and megakaryocytes. EMBO J. 15, 319-333 (1996).
25. Nagamine, C. M., Chan, K. M., Kozak, C. A. & Lau, Y. F. Chromosome mapping and expression of a putative testis-determining gene in the mouse. Science 243, 80-83 (1989).
26. Andrews, N. C. & Faller, D. V. A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells. Nucleic Acids Res. 19, 2499 (1991).
27. Pandolfi, P. P. et al. Targeted disruption of the GATA3 gene causes severe abnormalities in the nervous system and in fetal liver haemalopoiesis. Nature Genet. 11, 40-44 (1995).
28. Mulder, M. P. et al. Positional mapping of loci in the DiGeorge critical region at chromosome 22q11 using a new marker (D22S183). Human Genet. 96, 133-141 (1995).
29. Wijgerde, M., Grosveld, F. & Fraser, P. Transcription complex stability and chromatin dynamics in vivo. Nature 377, 209-213 (1995).
30. Wong, P. M. C., Chung, S. W., Chui, D. H. K. & Eaves, C. J. Properties of the earliest clonogenic hemopoietic procursors to appear in the developing murine yolk sac. Proc. Natl Acad. Sci. USA 83, 3851-3854 (1986).