The transcription factor Bright associates with Bruton's tyrosine kinase, the defective protein in immunodeficiency disease

Journal of Immunology

Volumn 165, Issue 12, 2000, Pages 6956-6965

  Webb, C F ^a   Yamashita, Y ^a   Ayers, N ^a   Evetts, S ^a   Paulin, Y ^a   Conley, M E ^a   Smith, E A ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLYCOPROTEIN GP 39; IMMUNOGLOBULIN; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA BINDING; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; IMMUNE DEFICIENCY; IMMUNOGLOBULIN PRODUCTION; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SPLEEN CELL; X CHROMOSOME LINKAGE;

EID: 0034672041     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.12.6956     Document Type: Article

References (80)

1. Novel protein-DNA interactions associated with increased immunoglobulin transcription in response to antigen plus interleukin-5
2. The immunoglobulin heavy-chain matrix-associating regions are bound by Bright a B cell-specific trans-activator that describes a new DNA-binding protein family
3. Induction of immunoglobulin μ mRNA in a B cell transfectant stimulated with interleukin-5 and a T-dependent antigen
4. Cux/CDP homeoprotein is a component of NF-μNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the Bright transcription activator
5. Expression of Bright at two distinct stages of B lymphocyte development
6. Transcription factors required for lymphoid lineage commitment
7. Transcription factors controlling B-cell development
8. B lymphocyte development and transcription regulation in vivo
9. In vivo ablation of surface immunoglobulin on mature B cells by inducible gene targeting results in rapid cell death
10. Genetic analysis of tyrosine kinase function in B cell development
11. X-linked agammaglobulinemia new approaches to old questions based on the identification of the defective gene
12. Deficient expression of a B cell cytoplasmic tyrosine kinase in human X-linked agammaglobulinemia
13. The gene involved in X-linked agammaglobulinaemia is a member of the src family of protein-tyrosine kinases
14. Mutation of the unique region of Bruton's tyrosine kinase in immunodeficient XID mice
15. Colocalization of X-linked agammaglobulinemia and X-linked immunodeficiency genes
16. The Bruton's tyrosine kinase gene is expressed throughout B cell differentiation, from early precursor B cell stages preceding immunoglobulin gene rearrangement up to mature B cell stages
17. Expression of Bruton's tyrosine kinase protein within the B cell lineage
18. Impaired expansion of mouse B cell progenitors lacking Btk
19. Defective B cell development and function in Btk-deficient mice
20. Inactivation of Btk by insertion of lacZ reveals defects in B cell development only past the pre-B cell stage
21. Expression of Bruton's tyrosine kinase in B lymphoblastoid cell lines from x-linked agammaglobulinaemia patients
22. Identification of novel Bruton's tyrosine kinase mutations in 10 unrelated subjects with X linked agammaglobulinaemia
23. Mutations in Btk in patients with presumed X-linked agammaglobulinemia
24. BTKbase, mutation database for X-linked agammaglobulinemia (XLA)
25. IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases
26. B-cell antigen receptor stimulation activates the human Bruton's tyrosine kinase, which is deficient in x-linked agammaglobulinemia
27. Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells
28. Temporal differences in the activation of three classes of non-transmembrane protein tyrosine kinases following B-cell antigen receptor surface engagement
29. Phosphorylation of two regulatory tyrosine residues in the activation of Bruton's tyrosine kinase via alternative receptors
30. Transphosphorylation of Bruton's tyrosine kinase on tyrosine 551 is critical for B cell antigen receptor function
31. An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro, and in vivo
32. 2+ following B-cell receptor activation
33. 3)/Tec kinase-dependent calcium signaling pathway a target for SHIP-mediated inhibitory signals
34. A comparative analysis of the phosphoinositide binding specificity of pleckstrin homology domains
35. SHIP modulates immune receptor responses by regulating membrane association of Btk
36. The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C
37. Binding of βγ subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase
38. Identification of the binding site for G(q)α on its effector Bruton's tyrosine kinase
39. SH3 domain of Bruton's tyrosine kinase can bind to proline-rich peptides of TH domain of the kinase and p120(cbl)
40. The SH3 domain of Bruton's tyrosine kinase interacts with Vav, Sam68 and EWS
41. Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction
42. BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement
43. Cloning of an Inr- and E-box-binding protein, TFII-I, that interacts physically and functionally with USFI
44. Regulation of nuclear localization and transcriptional activity of TFII-I by Bruton's tyrosine kinase
45. A monoclonal antibody against a murine CD38 homologue delivers a signal to B cells for prolongation of survival and protection against apoptosis in vitro unresponsiveness of X-linked immunodeficient B cells
46. Murine B cell proliferation and protection from apoptosis with an antibody against a 105-kD molecule unresponsiveness of X-linked immunodeficient B cells
47. Effect of anti-γ3 antibodies on immunoglobulin isotype expression in lipopolysaccharide-stimulated cultures of mouse spleen cells
48. Induction of germ-line γ1 and ε Ig gene expression in murine B cells
49. Differential transcription efficiency of two Ig V(H) promoters in vitro
50. CD38 signal transduction in human B cell precursors rapid induction of tyrosine phosphorylation, activation of syk tyrosine kinase, and phosphorylation of phospholipase C-γ and phosphatidylinositol 3-kinase
51. A topoisomerase II-like protein is part of an inducible DNA-binding protein complex that binds 5' of an immunoglobulin promoter
52. Mechanism of topoisomerase II inhibition by staurosporine and other protein kinase inhitors
53. Sequential induction of NF-κB/Rel family proteins during B-cell terminal differentiation
54. Molecular principles of Oct2-mediated gene activation in B cells
55. Role of the OCTA site in regulation of IgH chain gene transcription during B cell activation
56. XID affects events leading to B cell cycle entry
57. Bruton's tyrosine kinase links the B cell receptor to nuclear factor κB activation
58. Mutation of the pleckstrin homology domain of Bruton's tyrosine kinase in immunodeficiency impaired inositol 1,3,4,5-tetrakisphosphate binding capacity
59. Distinct specificity in the recognition of phosphoinositides by the pleckstrin homology domains of dynamin and Bruton's tyrosine kinase
60. Structure of the PH domain and btk motif from Bruton's tyrosine kinase molecular explanations for X-linked agammaglobulinaemia
61. Missense mutations affecting a conserved cysteine pair in the TH domain of Btk
62. Txk, a nonreceptor tyrosine kinase of the Tec family, is expressed in T helper type 1 cells and regulates interferon γ production in human T lymphocytes
63. Redistribution of Bruton's tyrosine kinase by activation of phosphatidylinositol 3-kinase and Rho-family GTPases
64. Phosphatidylinositol 3-kinase-dependent membrane association of the Bruton's tyrosine kinase pleckstrin homology domain visualized in single living cells
65. Bruton's tyrosine kinase is required for activation of IκB kinase and nuclear factor κB in response to B cell receptor engagement
66. Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling
67. Phosphatidylinositol 3-kinase in HL-60 nuclei is bound to the nuclear matrix and increases during granulocytic differentiation
68. Immunologic memory to phosphocholine VII Lack of T15 V1 gene utilization in Xid anti-PC hybridomas
69. The CBA/N mouse strain an experimental model illustrating the influence of the X-chromosome on immunity
70. Regulation and expression of immunoglobulin heavy chains
71. A differential location of phosphoinositide kinases, diacylglycerol kinase, and phospholipase C in the nuclear matrix
72. An alternative pathway for transcription initiation involving TFII-I
73. TFII-I regulates Vβ promoter activity through an initiator element
74. Cooperative interaction of an initiator-binding transcription initiation factor and the helix-loop-helix activator USF
75. TFII-I enhances activation of the c-fos promoter through interactions with upstream elements
76. Family-specific differences in transcription efficiency of Ig heavy-chain promoters
77. Regulation of TFII-I activity by phosphorylation
78. The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes
79. B-cell-specific coactivator OBF-1/OCA-B/Bob1 required for immune response and germinal centre formation
80. Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival