Phosphatidylinositol 3,4,5-trisphosphate regulates Ca2+ entry via Btk in platelets and megakaryocytes without increasing phospholipase C activity

EMBO Journal

Volumn 19, Issue 12, 2000, Pages 2793-2802

  Pasquet, Jean Max ^c   Quek, Lynn ^c   Stevens, Christiaan ^a   Bobe, Régis ^c   Huber, Michael ^b   Duronio, Vincent ^a   Krystal, Gerald ^b   Watson, Steve P ^c  

^a JACK BELL RESEARCH CENTRE   (Canada)

^b BRITISH COLUMBIA CANCER AGENCY   (Canada)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Btk; Phosphatidylinositol 3,4,5 trisphosphate; Phospholipase C; Platelets; X linked immunodeficiency

Indexed keywords

AMINOPHOSPHOLIPID; CALCIUM ION; COLLAGEN; GLYCOPROTEIN; INOSITOL PHOSPHATE; PADGEM PROTEIN; PEPTIDE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; PHOSPHOLIPASE C; RECEPTOR; TYROSINE;

ARTICLE; CALCIUM TRANSPORT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MEGAKARYOCYTE; MICROINJECTION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THROMBOCYTE; X CHROMOSOME LINKAGE;

EID: 0034660077     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/19.12.2793     Document Type: Article

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