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Volumn 66, Issue SUPPL. 7, 2005, Pages 5-13

The neurobiology of depression: Inroads to treatment and new drug discovery

Author keywords

[No Author keywords available]

Indexed keywords

3 (6 DIMETHYLAMINO 4 METHYL 3 PYRIDINYL) 7 DIPROPYLAMINO 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDINE; ANTALARMIN; ANTIDEPRESSANT AGENT; BUTYL[2,5 DIMETHYL 7 (2,4,6 TRIMETHYLPHENYL) 7H PYRROLO[2,3 D]PYRIMIDIN 4 YL]ETHYLAMINE; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; CORTICOTROPIN RELEASING FACTOR RECEPTOR 1; CORTICOTROPIN RELEASING FACTOR RECEPTOR 2; HYDROCORTISONE; NBI 34041; NEFAZODONE; PAROXETINE; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

EID: 25144441630     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper
Times cited : (344)

References (83)
  • 1
    • 1542306717 scopus 로고    scopus 로고
    • The burden of complex genetics in brain disorders
    • Uhl GR, Grow RW. The burden of complex genetics in brain disorders. Arch Gen Psychiatry 2004;61:223-229
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 223-229
    • Uhl, G.R.1    Grow, R.W.2
  • 2
    • 4444272087 scopus 로고    scopus 로고
    • Childhood and adolescent predictors of major depression in the transition to adulthood
    • Reinherz HZ, Paradis AD, Giaconia RM, et al. Childhood and adolescent predictors of major depression in the transition to adulthood. Am J Psychiatry 2003;160:2141-2147
    • (2003) Am J Psychiatry , vol.160 , pp. 2141-2147
    • Reinherz, H.Z.1    Paradis, A.D.2    Giaconia, R.M.3
  • 3
    • 2442673159 scopus 로고    scopus 로고
    • Life stress, genes, and depression: Multiple pathways lead to increased risk and new opportunities for intervention
    • Charney DS, Manji HK. Life stress, genes, and depression: multiple pathways lead to increased risk and new opportunities for intervention. Sci STKE 2004;225:re5
    • (2004) Sci STKE , vol.225
    • Charney, D.S.1    Manji, H.K.2
  • 4
  • 5
    • 0033966919 scopus 로고    scopus 로고
    • Family-based linkage disequilibrium mapping using SNP marker haplotypes: Application to a potential locus for schizophrenia at chromosome 22q11
    • Li T, Ball D, Zhao J, et al. Family-based linkage disequilibrium mapping using SNP marker haplotypes: application to a potential locus for schizophrenia at chromosome 22q11. Mol Psychiatry 2000;5:77-84
    • (2000) Mol Psychiatry , vol.5 , pp. 77-84
    • Li, T.1    Ball, D.2    Zhao, J.3
  • 6
    • 4644303054 scopus 로고    scopus 로고
    • Investigation of serotonin-related genes in antidepressant response
    • Peters EJ, Slager SL, McGrath PJ, et al. Investigation of serotonin-related genes in antidepressant response. Mol Psychiatry 2004;9:879-889
    • (2004) Mol Psychiatry , vol.9 , pp. 879-889
    • Peters, E.J.1    Slager, S.L.2    McGrath, P.J.3
  • 7
    • 2342619567 scopus 로고    scopus 로고
    • High-throughput morphometric analysis of individual neurons
    • Wu CC, Reilly JF, Young WG, et al. High-throughput morphometric analysis of individual neurons. Cereb Cortex 2004;14:543-554
    • (2004) Cereb Cortex , vol.14 , pp. 543-554
    • Wu, C.C.1    Reilly, J.F.2    Young, W.G.3
  • 8
    • 0030320649 scopus 로고    scopus 로고
    • A novel functional polymorphism within the promoter of the serotonin transporter gene: Possible role insusceptibility to affective disorders
    • Collier DA, Stober G, Li T, et al. A novel functional polymorphism within the promoter of the serotonin transporter gene: possible role insusceptibility to affective disorders. Mol Psychiatry 1996;1:453-460
    • (1996) Mol Psychiatry , vol.1 , pp. 453-460
    • Collier, D.A.1    Stober, G.2    Li, T.3
  • 9
    • 0006463359 scopus 로고    scopus 로고
    • Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region
    • Lesch KP, Bengel D, Heils A, et al. Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996;274:1527-1531
    • (1996) Science , vol.274 , pp. 1527-1531
    • Lesch, K.P.1    Bengel, D.2    Heils, A.3
  • 10
    • 1542373739 scopus 로고    scopus 로고
    • Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype
    • van Dyck CH, Malison RT, Staley JK, et al. Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype. Am J Psychiatry 2004;161:525-531
    • (2004) Am J Psychiatry , vol.161 , pp. 525-531
    • Van Dyck, C.H.1    Malison, R.T.2    Staley, J.K.3
  • 11
    • 0032526625 scopus 로고    scopus 로고
    • Serotonin transporter gene variants in alcohol-dependent subjects with dissocial personality disorder
    • Sander T, Harms H, Dufeu P, et al. Serotonin transporter gene variants in alcohol-dependent subjects with dissocial personality disorder. Biol Psychiatry 1998;43:908-912
    • (1998) Biol Psychiatry , vol.43 , pp. 908-912
    • Sander, T.1    Harms, H.2    Dufeu, P.3
  • 12
    • 0343238139 scopus 로고    scopus 로고
    • Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample
    • Greenberg BD, Li Q, Lucas FR, et al. Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample. Am J Med Genet 2000;96:202-216
    • (2000) Am J Med Genet , vol.96 , pp. 202-216
    • Greenberg, B.D.1    Li, Q.2    Lucas, F.R.3
  • 13
    • 1542283785 scopus 로고    scopus 로고
    • Association between allelic variation of serotonin transporter function and neuroticism in anxious cluster C personality disorders
    • Jacob CP, Strobel A, Hohenberger K, et al. Association between allelic variation of serotonin transporter function and neuroticism in anxious cluster C personality disorders. Am J Psychiatry 2004;161:569-572
    • (2004) Am J Psychiatry , vol.161 , pp. 569-572
    • Jacob, C.P.1    Strobel, A.2    Hohenberger, K.3
  • 14
    • 17744384689 scopus 로고    scopus 로고
    • Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease
    • Mossner R, Henneberg A, Schmitt A, et al. Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease. Mol Psychiatry 2001;6:350-352
    • (2001) Mol Psychiatry , vol.6 , pp. 350-352
    • Mossner, R.1    Henneberg, A.2    Schmitt, A.3
  • 15
    • 0036328051 scopus 로고    scopus 로고
    • Evolutionary conserved microsatellites in the promoter region of the 5-hydroxytryptamine receptor 2C gene (HTR2C) are not associated with bipolar disorder in females
    • Meyer J, Saam W, Mossner R, et al. Evolutionary conserved microsatellites in the promoter region of the 5-hydroxytryptamine receptor 2C gene (HTR2C) are not associated with bipolar disorder in females. J Neural Transm 2002;109:939-946
    • (2002) J Neural Transm , vol.109 , pp. 939-946
    • Meyer, J.1    Saam, W.2    Mossner, R.3
  • 16
    • 0034237022 scopus 로고    scopus 로고
    • Polymorphic MAO-A and 5-HT-transporter genes: Analysis of interactions in panic disorder
    • Sand P, Lesch KP, Catalano M, et al. Polymorphic MAO-A and 5-HT-transporter genes: analysis of interactions in panic disorder. World J Biol Psychiatry 2000;1:147-150
    • (2000) World J Biol Psychiatry , vol.1 , pp. 147-150
    • Sand, P.1    Lesch, K.P.2    Catalano, M.3
  • 17
    • 10344238087 scopus 로고    scopus 로고
    • Social supports and serotonin transporter gene moderate depression in maltreated children
    • Kaufman J, Yang BZ, Douglas-Palumberi H, et al. Social supports and serotonin transporter gene moderate depression in maltreated children. Proc Natl Acad Sci U S A 2004;101:17316-17321
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17316-17321
    • Kaufman, J.1    Yang, B.Z.2    Douglas-Palumberi, H.3
  • 18
    • 0037624040 scopus 로고    scopus 로고
    • Influence of life stress on depression: Moderation by a polymorphism in the 5-HTT gene
    • Caspi A, Sugden K, Moffitt TE, et al. Influence of life stress on depression: moderation by a polymorphism in the 5-HTT gene. Science 2003;301:386-389
    • (2003) Science , vol.301 , pp. 386-389
    • Caspi, A.1    Sugden, K.2    Moffitt, T.E.3
  • 19
    • 0034127008 scopus 로고    scopus 로고
    • Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress
    • Bale TL, Contarino A, Smith GW, et al. Mice deficient for corticotropin-releasing hormone receptor-2 display anxiety-like behaviour and are hypersensitive to stress. Nat Genet 2000;24:410-414
    • (2000) Nat Genet , vol.24 , pp. 410-414
    • Bale, T.L.1    Contarino, A.2    Smith, G.W.3
  • 20
    • 0032091519 scopus 로고    scopus 로고
    • The neurobiology of depression
    • Nemeroff CB. The neurobiology of depression. Sci Am 1998;278:42-49
    • (1998) Sci Am , vol.278 , pp. 42-49
    • Nemeroff, C.B.1
  • 21
    • 0019782980 scopus 로고
    • Characterization of a 41 residue ovine hypothalamic peptide that stimulates the secretion of corticotropin and beta-endorphin
    • Vale W, Spiess J, Rivier C, et al. Characterization of a 41 residue ovine hypothalamic peptide that stimulates the secretion of corticotropin and beta-endorphin. Science 1981;213:1394-1397
    • (1981) Science , vol.213 , pp. 1394-1397
    • Vale, W.1    Spiess, J.2    Rivier, C.3
  • 22
    • 1342281225 scopus 로고    scopus 로고
    • CRF and CRF receptors: Role in stress responsivity and other behaviors
    • Bale TL, Vale WW. CRF and CRF receptors: role in stress responsivity and other behaviors. Annu Rev Pharmacol Toxicol 2004;44:525-557
    • (2004) Annu Rev Pharmacol Toxicol , vol.44 , pp. 525-557
    • Bale, T.L.1    Vale, W.W.2
  • 23
    • 0027489208 scopus 로고
    • Expression cloning of a human corticotropin-releasing-factor receptor
    • Chen R, Lewis KA, Perrin MH, et al. Expression cloning of a human corticotropin-releasing-factor receptor. Proc Natl Acad Sci U S A 1993;90:8967-8971
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 8967-8971
    • Chen, R.1    Lewis, K.A.2    Perrin, M.H.3
  • 24
    • 0037370129 scopus 로고    scopus 로고
    • International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands
    • Hauger RL, Grigoriadis DE, Dallman MF, et al. International Union of Pharmacology. XXXVI. Current status of the nomenclature for receptors for corticotropin-releasing factor and their ligands. Pharmacol Rev 2003;55:21-26
    • (2003) Pharmacol Rev , vol.55 , pp. 21-26
    • Hauger, R.L.1    Grigoriadis, D.E.2    Dallman, M.F.3
  • 25
    • 0028819695 scopus 로고
    • Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor
    • Vaughan J, Donaldson C, Bittencourt J, et al. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor. Nature 1995;378:287-292
    • (1995) Nature , vol.378 , pp. 287-292
    • Vaughan, J.1    Donaldson, C.2    Bittencourt, J.3
  • 26
    • 0000432665 scopus 로고    scopus 로고
    • Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor
    • Hsu SY, Hsueh AJ. Human stresscopin and stresscopin-related peptide are selective ligands for the type 2 corticotropin-releasing hormone receptor. Nat Med 2001;7:605-611
    • (2001) Nat Med , vol.7 , pp. 605-611
    • Hsu, S.Y.1    Hsueh, A.J.2
  • 27
    • 0035912712 scopus 로고    scopus 로고
    • Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor
    • Lewis K, Li C, Perrin MH, et al. Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor. Proc Natl Acad Sci U S A 2001;98: 7570-7575
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 7570-7575
    • Lewis, K.1    Li, C.2    Perrin, M.H.3
  • 28
    • 0035956938 scopus 로고    scopus 로고
    • Urocortin II: A member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors
    • Reyes TM, Lewis K, Perrin MH, et al. Urocortin II: a member of the corticotropin-releasing factor (CRF) neuropeptide family that is selectively bound by type 2 CRF receptors. Proc Natl Acad Sci U S A 2001;98: 2843-2848
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2843-2848
    • Reyes, T.M.1    Lewis, K.2    Perrin, M.H.3
  • 29
    • 0038303469 scopus 로고    scopus 로고
    • Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonist
    • Valdez GR, Zorrilla EP, Rivier J, et al. Locomotor suppressive and anxiolytic-like effects of urocortin 3, a highly selective type 2 corticotropin-releasing factor agonist. Brain Res 2003;980:206-212
    • (2003) Brain Res , vol.980 , pp. 206-212
    • Valdez, G.R.1    Zorrilla, E.P.2    Rivier, J.3
  • 30
    • 7044239186 scopus 로고    scopus 로고
    • Spontaneous withdrawal from the triazolobenzodiazepine alprazolam increases cortical corticotropin-releasing factor mRNA expression
    • Skelton KH, Nemeroff CB, Owens MJ. Spontaneous withdrawal from the triazolobenzodiazepine alprazolam increases cortical corticotropin-releasing factor mRNA expression. J Neurosci 2004;24:9303-9312
    • (2004) J Neurosci , vol.24 , pp. 9303-9312
    • Skelton, K.H.1    Nemeroff, C.B.2    Owens, M.J.3
  • 31
    • 0032104267 scopus 로고    scopus 로고
    • Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development
    • Smith GW, Aubry JM, Dellu F, et al. Corticotropin releasing factor receptor 1-deficient mice display decreased anxiety, impaired stress response, and aberrant neuroendocrine development. Neuron 1998;20:1093-1102
    • (1998) Neuron , vol.20 , pp. 1093-1102
    • Smith, G.W.1    Aubry, J.M.2    Dellu, F.3
  • 32
    • 17344362093 scopus 로고    scopus 로고
    • Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1
    • Timpl P, Spanagel R, Sillaber I, et al. Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1. Nat Genet 1998;19:162-166
    • (1998) Nat Genet , vol.19 , pp. 162-166
    • Timpl, P.1    Spanagel, R.2    Sillaber, I.3
  • 33
    • 0034087469 scopus 로고    scopus 로고
    • Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin-releasing hormone receptor-2
    • Coste SC, Kesterson RA, Heldwein KA, et al. Abnormal adaptations to stress and impaired cardiovascular function in mice lacking corticotropin- releasing hormone receptor-2. Nat Genet 2000;24:403-409
    • (2000) Nat Genet , vol.24 , pp. 403-409
    • Coste, S.C.1    Kesterson, R.A.2    Heldwein, K.A.3
  • 34
    • 0036137946 scopus 로고    scopus 로고
    • Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior
    • Bale TL, Picetti R, Contarino A, et al. Mice deficient for both corticotropin-releasing factor receptor 1 (CRFR1) and CRFR2 have an impaired stress response and display sexually dichotomous anxiety-like behavior. J Neurosci 2002;22:193-199
    • (2002) J Neurosci , vol.22 , pp. 193-199
    • Bale, T.L.1    Picetti, R.2    Contarino, A.3
  • 35
    • 0023251249 scopus 로고
    • CSF corticotropin-releasing factor-like immunoreactivity in depression and schizophrenia
    • Banki CM, Bissette G, Arato M, et al. CSF corticotropin-releasing factor-like immunoreactivity in depression and schizophrenia. Am J Psychiatry 1987;144:873-877
    • (1987) Am J Psychiatry , vol.144 , pp. 873-877
    • Banki, C.M.1    Bissette, G.2    Arato, M.3
  • 36
    • 1242314197 scopus 로고    scopus 로고
    • Dysregulation in the suicide brain: MRNA expression of corticotropin-releasing hormone receptors and GABA(A) receptor subunits in frontal cortical brain region
    • Merali Z, Du L, Hrdina P, et al. Dysregulation in the suicide brain: mRNA expression of corticotropin-releasing hormone receptors and GABA(A) receptor subunits in frontal cortical brain region. J Neurosci 2004;24: 1478-1485
    • (2004) J Neurosci , vol.24 , pp. 1478-1485
    • Merali, Z.1    Du, L.2    Hrdina, P.3
  • 37
    • 0021714606 scopus 로고
    • Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients
    • Nemeroff CB, Widerlov E, Bissette G, et al. Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients. Science 1984;226:1342-1344
    • (1984) Science , vol.226 , pp. 1342-1344
    • Nemeroff, C.B.1    Widerlov, E.2    Bissette, G.3
  • 38
    • 0027936468 scopus 로고
    • Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients
    • Raadsheer FC, Hoogendijk WJ, Stam FC, et al. Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients. Neuroendocrinology 1994; 60:436-444
    • (1994) Neuroendocrinology , vol.60 , pp. 436-444
    • Raadsheer, F.C.1    Hoogendijk, W.J.2    Stam, F.C.3
  • 39
    • 0026513007 scopus 로고
    • Childhood parental loss and adult psychopathology in women: A twin study perspective
    • Kendler KS, Neale MC, Kessler RC, et al. Childhood parental loss and adult psychopathology in women: a twin study perspective. Arch Gen Psychiatry 1992;49:109-116
    • (1992) Arch Gen Psychiatry , vol.49 , pp. 109-116
    • Kendler, K.S.1    Neale, M.C.2    Kessler, R.C.3
  • 40
    • 5644269352 scopus 로고    scopus 로고
    • Adverse childhood experiences and the risk of depressive disorders in adulthood
    • Chapman DP, Whitfield CL, Felitti VJ, et al. Adverse childhood experiences and the risk of depressive disorders in adulthood. J Affect Disord 2004;82:217-225
    • (2004) J Affect Disord , vol.82 , pp. 217-225
    • Chapman, D.P.1    Whitfield, C.L.2    Felitti, V.J.3
  • 41
    • 0035956483 scopus 로고    scopus 로고
    • Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: Findings from the Adverse Childhood Experiences Study
    • Dube SR, Anda RF, Felitti VJ, et al. Childhood abuse, household dysfunction, and the risk of attempted suicide throughout the life span: findings from the Adverse Childhood Experiences Study. JAMA 2001;286: 3089-3096
    • (2001) JAMA , vol.286 , pp. 3089-3096
    • Dube, S.R.1    Anda, R.F.2    Felitti, V.J.3
  • 42
    • 0030896520 scopus 로고    scopus 로고
    • Clinical characteristics of women with a history of childhood abuse: Unhealed wounds
    • McCauley J, Kern DE, Kolodner K, et al. Clinical characteristics of women with a history of childhood abuse: unhealed wounds. JAMA 1997;277: 1362-1368
    • (1997) JAMA , vol.277 , pp. 1362-1368
    • McCauley, J.1    Kern, D.E.2    Kolodner, K.3
  • 43
    • 0036315095 scopus 로고    scopus 로고
    • History of childhood abuse in panic disorder, social phobia, and generalized anxiety disorder
    • Safren SA, Gershuny BS, Marzol P, et al. History of childhood abuse in panic disorder, social phobia, and generalized anxiety disorder. J Nerv Ment Dis 2002;190:453-456
    • (2002) J Nerv Ment Dis , vol.190 , pp. 453-456
    • Safren, S.A.1    Gershuny, B.S.2    Marzol, P.3
  • 44
    • 0041381412 scopus 로고    scopus 로고
    • Persistent central nervous system effects of an adverse early environment: Clinical and preclinical studies
    • Gutman DA, Nemeroff CB. Persistent central nervous system effects of an adverse early environment: clinical and preclinical studies. Physiol Behav 2003;79:471-178
    • (2003) Physiol Behav , vol.79 , pp. 471-1178
    • Gutman, D.A.1    Nemeroff, C.B.2
  • 45
    • 0035072969 scopus 로고    scopus 로고
    • Altered pituitary-adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse
    • Heim C, Newport DJ, Bonsall R, et al. Altered pituitary-adrenal axis responses to provocative challenge tests in adult survivors of childhood abuse. Am J Psychiatry 2001;158:575-581
    • (2001) Am J Psychiatry , vol.158 , pp. 575-581
    • Heim, C.1    Newport, D.J.2    Bonsall, R.3
  • 46
    • 0034596146 scopus 로고    scopus 로고
    • Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood
    • Heim C, Newport DJ, Heit S, et al. Pituitary-adrenal and autonomic responses to stress in women after sexual and physical abuse in childhood. JAMA 2000;284:592-597
    • (2000) JAMA , vol.284 , pp. 592-597
    • Heim, C.1    Newport, D.J.2    Heit, S.3
  • 47
    • 0034210114 scopus 로고    scopus 로고
    • Developmental stress disrupts habituation but spares prepulse inhibition in young rats
    • Finamore TL, Port RL. Developmental stress disrupts habituation but spares prepulse inhibition in young rats. Physiol Behav 2000;69:527-530
    • (2000) Physiol Behav , vol.69 , pp. 527-530
    • Finamore, T.L.1    Port, R.L.2
  • 48
    • 27744501266 scopus 로고    scopus 로고
    • Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring
    • In press
    • Plotsky PM, Thrivikraman KV, Nemeroff CB, et al. Long-term consequences of neonatal rearing on central corticotropin-releasing factor systems in adult male rat offspring. Neuropsychopharmacology. In press
    • Neuropsychopharmacology
    • Plotsky, P.M.1    Thrivikraman, K.V.2    Nemeroff, C.B.3
  • 49
    • 0034000440 scopus 로고    scopus 로고
    • Long-term behavioral and neuroendocrine adaptations to adverse early experience
    • Ladd CO, Huot RL, Thrivikraman KV, et al. Long-term behavioral and neuroendocrine adaptations to adverse early experience. Prog Brain Res 2000;122:81-103
    • (2000) Prog Brain Res , vol.122 , pp. 81-103
    • Ladd, C.O.1    Huot, R.L.2    Thrivikraman, K.V.3
  • 50
    • 0027195888 scopus 로고
    • Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF con-tent and stress-induced release in adult rats
    • Plotsky PM, Meaney MJ. Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF con-tent and stress-induced release in adult rats. Brain Res Mol Brain Res 1993;18:195-200
    • (1993) Brain Res Mol Brain Res , vol.18 , pp. 195-200
    • Plotsky, P.M.1    Meaney, M.J.2
  • 51
    • 0036603867 scopus 로고    scopus 로고
    • 5-HT(1B) mRNA regulation in two animal models of altered stress reactivity
    • Neumaier JF, Edwards E, Plotsky PM. 5-HT(1B) mRNA regulation in two animal models of altered stress reactivity. Biol Psychiatry 2002;51: 902-908
    • (2002) Biol Psychiatry , vol.51 , pp. 902-908
    • Neumaier, J.F.1    Edwards, E.2    Plotsky, P.M.3
  • 52
    • 0033968689 scopus 로고    scopus 로고
    • The effects of early rearing environment on the development of GABA-A and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat
    • Caldji C, Francis D, Sharma S, et al. The effects of early rearing environment on the development of GABA-A and central benzodiazepine receptor levels and novelty-induced fearfulness in the rat. Neuropsychopharmacology 2000;22:219-229
    • (2000) Neuropsychopharmacology , vol.22 , pp. 219-229
    • Caldji, C.1    Francis, D.2    Sharma, S.3
  • 53
    • 0036135228 scopus 로고    scopus 로고
    • Environmental regulation of the development of mesolimbic dopamine systems: A neurobiological mechanism for vulnerability to drug abuse?
    • Meaney MJ, Brake W, Gratton A. Environmental regulation of the development of mesolimbic dopamine systems: a neurobiological mechanism for vulnerability to drug abuse? Psychoneuroendocrinology 2002;27:127-138
    • (2002) Psychoneuroendocrinology , vol.27 , pp. 127-138
    • Meaney, M.J.1    Brake, W.2    Gratton, A.3
  • 54
    • 0037144222 scopus 로고    scopus 로고
    • Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans rats
    • Huot RL, Plotsky PM, Lenox RH, et al. Neonatal maternal separation reduces hippocampal mossy fiber density in adult Long Evans rats. Brain Res 2002;950:52-63
    • (2002) Brain Res , vol.950 , pp. 52-63
    • Huot, R.L.1    Plotsky, P.M.2    Lenox, R.H.3
  • 55
    • 3343008569 scopus 로고    scopus 로고
    • Early life experience alters response of adult neurogenesis to stress
    • Mirescu C, Peters JD, Gould E. Early life experience alters response of adult neurogenesis to stress. Nat Neurosci 2004;7:841-846
    • (2004) Nat Neurosci , vol.7 , pp. 841-846
    • Mirescu, C.1    Peters, J.D.2    Gould, E.3
  • 56
    • 0035207885 scopus 로고    scopus 로고
    • Development of adult ethanol preference and anxiety as a consequence of neonatal maternal separation in Long Evans rats and reversal with antidepressant treatment
    • Huot RL, Thrivikraman KV, Meaney MJ, et al. Development of adult ethanol preference and anxiety as a consequence of neonatal maternal separation in Long Evans rats and reversal with antidepressant treatment. Psychopharmacology (Berl) 2001;158:366-373
    • (2001) Psychopharmacology (Berl) , vol.158 , pp. 366-373
    • Huot, R.L.1    Thrivikraman, K.V.2    Meaney, M.J.3
  • 57
    • 0032955610 scopus 로고    scopus 로고
    • Repeated neonatal maternal separation alters intravenous cocaine self-administration in adult rats
    • Matthews K, Robbins TW, Everitt BJ, et al. Repeated neonatal maternal separation alters intravenous cocaine self-administration in adult rats. Psychopharmacology (Berl) 1999;141:123-134
    • (1999) Psychopharmacology (Berl) , vol.141 , pp. 123-134
    • Matthews, K.1    Robbins, T.W.2    Everitt, B.J.3
  • 58
    • 0032574785 scopus 로고    scopus 로고
    • Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat
    • Caldji C, Tannenbaum B, Sharma S, et al. Maternal care during infancy regulates the development of neural systems mediating the expression of fearfulness in the rat. Proc Natl Acad Sci U S A 1998;95:5335-5340
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 5335-5340
    • Caldji, C.1    Tannenbaum, B.2    Sharma, S.3
  • 59
    • 0036331052 scopus 로고    scopus 로고
    • Parental depression: Animal models of an adverse life event
    • Newport DJ, Stowe ZN, Nemeroff CB. Parental depression: animal models of an adverse life event. Am J Psychiatry 2002;159:1265-1283
    • (2002) Am J Psychiatry , vol.159 , pp. 1265-1283
    • Newport, D.J.1    Stowe, Z.N.2    Nemeroff, C.B.3
  • 60
    • 0242289457 scopus 로고    scopus 로고
    • Foster litters prevent hypothalamic-pituitary-adrenal axis sensitization mediated by neonatal maternal separation
    • Huot RL, Gonzalez ME, Ladd CO, et al. Foster litters prevent hypothalamic-pituitary-adrenal axis sensitization mediated by neonatal maternal separation. Psychoneuroendocrinology 2004;29:279-289
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 279-289
    • Huot, R.L.1    Gonzalez, M.E.2    Ladd, C.O.3
  • 61
    • 0037107176 scopus 로고    scopus 로고
    • Environmental enrichment reverses the effects of maternal separation on stress reactivity
    • Francis DD, Diorio J, Plotsky PM, et al. Environmental enrichment reverses the effects of maternal separation on stress reactivity. J Neurosci 2002;22:7840-7843
    • (2002) J Neurosci , vol.22 , pp. 7840-7843
    • Francis, D.D.1    Diorio, J.2    Plotsky, P.M.3
  • 62
    • 0037051872 scopus 로고    scopus 로고
    • Placebo response in studies of major depression: Variable, substantial, and growing
    • Walsh BT, Seidman SN, Sysko R, et al. Placebo response in studies of major depression: variable, substantial, and growing. JAMA 2002;287:1840-1847
    • (2002) JAMA , vol.287 , pp. 1840-1847
    • Walsh, B.T.1    Seidman, S.N.2    Sysko, R.3
  • 63
    • 0030064218 scopus 로고    scopus 로고
    • The long-term impact of the physical, emotional, and sexual abuse of children: A community study
    • Mullen PE, Martin JL, Anderson JC, et al. The long-term impact of the physical, emotional, and sexual abuse of children: a community study. Child Abuse Negl 1996;20:7-21
    • (1996) Child Abuse Negl , vol.20 , pp. 7-21
    • Mullen, P.E.1    Martin, J.L.2    Anderson, J.C.3
  • 64
    • 0031427087 scopus 로고    scopus 로고
    • Childhood adversity and vulnerability to mood and anxiety disorders
    • Young EA, Abelson JL, Curtis GC, et al. Childhood adversity and vulnerability to mood and anxiety disorders. Depress Anxiety 1997;5:66-72
    • (1997) Depress Anxiety , vol.5 , pp. 66-72
    • Young, E.A.1    Abelson, J.L.2    Curtis, G.C.3
  • 65
    • 0037676181 scopus 로고    scopus 로고
    • Cerebrospinal fluid corticotropin-releasing factor (CRF) and vasopressin concentrations predict pituitary response in the CRF stimulation test: A multiple regression analysis
    • Newport DJ, Heim C, Owens MJ, et al. Cerebrospinal fluid corticotropin-releasing factor (CRF) and vasopressin concentrations predict pituitary response in the CRF stimulation test: a multiple regression analysis. Neuropsychopharmacology 2003;28:569-576
    • (2003) Neuropsychopharmacology , vol.28 , pp. 569-576
    • Newport, D.J.1    Heim, C.2    Owens, M.J.3
  • 66
    • 1642529036 scopus 로고    scopus 로고
    • Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed patients and healthy control subjects
    • Carpenter LL, Tyrka AR, McDougle CJ, et al. Cerebrospinal fluid corticotropin-releasing factor and perceived early-life stress in depressed patients and healthy control subjects. Neuropsychopharmacology 2004;29:777-784
    • (2004) Neuropsychopharmacology , vol.29 , pp. 777-784
    • Carpenter, L.L.1    Tyrka, A.R.2    McDougle, C.J.3
  • 67
    • 0036895697 scopus 로고    scopus 로고
    • Childhood trauma associated with smaller hippocampal volume in women with major depression
    • Vythilingam M, Heim C, Newport J, et al. Childhood trauma associated with smaller hippocampal volume in women with major depression. Am J Psychiatry 2002;159:2072-2080
    • (2002) Am J Psychiatry , vol.159 , pp. 2072-2080
    • Vythilingam, M.1    Heim, C.2    Newport, J.3
  • 68
    • 0032557846 scopus 로고    scopus 로고
    • Amygdala core nuclei volumes are decreased in recurrent major depression
    • Sheline YI, Gado MH, Price JL. Amygdala core nuclei volumes are decreased in recurrent major depression. Neuroreport 1998;9:2023-2028
    • (1998) Neuroreport , vol.9 , pp. 2023-2028
    • Sheline, Y.I.1    Gado, M.H.2    Price, J.L.3
  • 69
    • 0031024960 scopus 로고    scopus 로고
    • Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse: A preliminary report
    • Bremner JD, Randall P, Vermetten E, et al. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse: a preliminary report. Biol Psychiatry 1997;41:23-32
    • (1997) Biol Psychiatry , vol.41 , pp. 23-32
    • Bremner, J.D.1    Randall, P.2    Vermetten, E.3
  • 70
    • 0030860094 scopus 로고    scopus 로고
    • Hippocampal volume in women victimized by childhood sexual abuse
    • Stein MB, Koverola C, Hanna C, et al. Hippocampal volume in women victimized by childhood sexual abuse. Psychol Med 1997;27:951-959
    • (1997) Psychol Med , vol.27 , pp. 951-959
    • Stein, M.B.1    Koverola, C.2    Hanna, C.3
  • 71
    • 0033135554 scopus 로고    scopus 로고
    • Cell atrophy in major depression
    • Duman RS, Charney DS. Cell atrophy in major depression [editorial]. Biol Psychiatry 1999;45:1083-1084
    • (1999) Biol Psychiatry , vol.45 , pp. 1083-1084
    • Duman, R.S.1    Charney, D.S.2
  • 72
    • 0035902478 scopus 로고    scopus 로고
    • Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early-life stress
    • Brunson KL, Eghbal-Ahmadi M, Bender R, et al. Long-term, progressive hippocampal cell loss and dysfunction induced by early-life administration of corticotropin-releasing hormone reproduce the effects of early-life stress. Proc Natl Acad Sci U S A 2001;98:8856-8861
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 8856-8861
    • Brunson, K.L.1    Eghbal-Ahmadi, M.2    Bender, R.3
  • 73
    • 25144494941 scopus 로고    scopus 로고
    • Childhood trauma is associated with altered neural processing related to emotion perception and memory
    • Kilts CD, Ely TD, Newport JD, et al. Childhood trauma is associated with altered neural processing related to emotion perception and memory [abstract]. Biol Psychiatry 2005;57:62S
    • (2005) Biol Psychiatry , vol.57
    • Kilts, C.D.1    Ely, T.D.2    Newport, J.D.3
  • 74
    • 0034682305 scopus 로고    scopus 로고
    • A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression
    • Keller MB, McCullough JP, Klein DN, et al. A comparison of nefazodone, the cognitive behavioral-analysis system of psychotherapy, and their combination for the treatment of chronic depression. N Engl J Med 2000;342:1462-1470
    • (2000) N Engl J Med , vol.342 , pp. 1462-1470
    • Keller, M.B.1    McCullough, J.P.2    Klein, D.N.3
  • 75
    • 10744223245 scopus 로고    scopus 로고
    • Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma
    • Nemeroff CB, Heim CM, Thase ME, et al. Differential responses to psychotherapy versus pharmacotherapy in patients with chronic forms of major depression and childhood trauma. Proc Natl Acad Sci U S A 2003;100: 14293-14296
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 14293-14296
    • Nemeroff, C.B.1    Heim, C.M.2    Thase, M.E.3
  • 76
    • 0037240648 scopus 로고    scopus 로고
    • New molecular targets for antianxiety interventions
    • Gorman JM. New molecular targets for antianxiety interventions. J Clin Psychiatry 2003;64(suppl 3):28-35
    • (2003) J Clin Psychiatry , vol.64 , Issue.SUPPL. 3 , pp. 28-35
    • Gorman, J.M.1
  • 77
    • 0034193881 scopus 로고    scopus 로고
    • Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: The first 20 patients treated
    • Zobel AW, Nickel T, Künzel HE, et al. Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated. J Psychiatr Res 2000;34:171-181
    • (2000) J Psychiatr Res , vol.34 , pp. 171-181
    • Zobel, A.W.1    Nickel, T.2    Künzel, H.E.3
  • 78
    • 0032892569 scopus 로고    scopus 로고
    • The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress
    • Deak T, Nguyen KT, Ehrlich AL, et al. The impact of the nonpeptide corticotropin-releasing hormone antagonist antalarmin on behavioral and endocrine responses to stress. Endocrinology 1999;140:79-86
    • (1999) Endocrinology , vol.140 , pp. 79-86
    • Deak, T.1    Nguyen, K.T.2    Ehrlich, A.L.3
  • 79
    • 0037359880 scopus 로고    scopus 로고
    • The pharmacology of CP-154,526, a non-peptide antagonist of the CRH1 receptor: A review
    • Seymour PA, Schmidt AW, Schulz DW. The pharmacology of CP-154,526, a non-peptide antagonist of the CRH1 receptor: a review. CNS Drug Rev 2003;9:57-96
    • (2003) CNS Drug Rev , vol.9 , pp. 57-96
    • Seymour, P.A.1    Schmidt, A.W.2    Schulz, D.W.3
  • 80
    • 0034092839 scopus 로고    scopus 로고
    • Effects of a novel corticotropin-releasing-hormone receptor type I antagonist on human adrenal function
    • Willenberg HS, Bornstein SR, Hiroi N, et al. Effects of a novel corticotropin-releasing-hormone receptor type I antagonist on human adrenal function. Mol Psychiatry 2000;5:137-141
    • (2000) Mol Psychiatry , vol.5 , pp. 137-141
    • Willenberg, H.S.1    Bornstein, S.R.2    Hiroi, N.3
  • 81
    • 0013522651 scopus 로고    scopus 로고
    • CP-154,526: A potent and selective nonpeptide antagonist of corticotropin releasing factor receptors
    • Schulz DW, Mansbach RS, Sprouse J, et al. CP-154,526: a potent and selective nonpeptide antagonist of corticotropin releasing factor receptors. Proc Natl Acad Sci U S A 1996;93:10477-10482
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 10477-10482
    • Schulz, D.W.1    Mansbach, R.S.2    Sprouse, J.3
  • 82
    • 0031960095 scopus 로고    scopus 로고
    • CP-154,526, a selective, non-peptide antagonist of the corticotropin-releasing factor 1 receptor attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats
    • Shaham Y, Erb S, Leung S, et al. CP-154,526, a selective, non-peptide antagonist of the corticotropin-releasing factor 1 receptor attenuates stress-induced relapse to drug seeking in cocaine- and heroin-trained rats. Psychopharmacology (Berl) 1998;137:184-190
    • (1998) Psychopharmacology (Berl) , vol.137 , pp. 184-190
    • Shaham, Y.1    Erb, S.2    Leung, S.3
  • 83
    • 0035111499 scopus 로고    scopus 로고
    • Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors
    • Thase ME, Entsuah AR, Rudolph RL. Remission rates during treatment with venlafaxine or selective serotonin reuptake inhibitors. Br J Psychiatry 2001;178:234-241
    • (2001) Br J Psychiatry , vol.178 , pp. 234-241
    • Thase, M.E.1    Entsuah, A.R.2    Rudolph, R.L.3


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