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Volumn 64, Issue SUPPL. 3, 2003, Pages 28-35

New molecular targets for antianxiety interventions

Author keywords

[No Author keywords available]

Indexed keywords

1 (4,4 DIPHENYL 3 BUTENYL)NIPECOTIC ACID; 3 (6 DIMETHYLAMINO 4 METHYL 3 PYRIDINYL) 7 DIPROPYLAMINO 2,5 DIMETHYLPYRAZOLO[1,5 A]PYRIMIDINE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID RECEPTOR STIMULATING AGENT; 5 [[2 [1 [3,5 BIS(TRIFLUOROMETHYL)PHENYL]ETHOXY] 3 (4 FLUOROPHENYL) 4 MORPHOLINYL]METHYL] N,N DIMETHYL 1H 1,2,3 TRIAZOLE 4 METHANAMINE; ALPRAZOLAM; ANXIOLYTIC AGENT; APREPITANT; BENZODIAZEPINE DERIVATIVE; BENZODIAZEPINE RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; CORTICOTROPIN RELEASING FACTOR; CORTICOTROPIN RELEASING FACTOR ANTAGONIST; DELORAZEPAM; DIAZEPAM; DIZOCILPINE; EGLUMETAD; FLUOXETINE; IMIPRAMINE; KETAMINE; NKP 608; NORADRENALIN; PAGOCLONE; PAROXETINE; PREGABALIN; SEROTONIN; SUBSTANCE P; SUBSTANCE P ANTAGONIST; TIAGABINE; TRAZODONE; TRIMIPRAMINE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VENLAFAXINE; VOFOPITANT;

EID: 0037240648     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (49)

References (45)
  • 1
    • 0034877353 scopus 로고    scopus 로고
    • Crossover trial of pagoclone and placebo in patients with DSM-IV panic disorder
    • Sandford JJ, Forshall S, Bell C, et al. Crossover trial of pagoclone and placebo in patients with DSM-IV panic disorder. J Psychopharmacol 2001; 15:205-208
    • (2001) J Psychopharmacol , vol.15 , pp. 205-208
    • Sandford, J.J.1    Forshall, S.2    Bell, C.3
  • 2
    • 0034108997 scopus 로고    scopus 로고
    • Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha 1 subtype
    • McKernan RM, Rosahl TW, Reynolds DS, et al. Sedative but not anxiolytic properties of benzodiazepines are mediated by the GABA(A) receptor alpha 1 subtype. Nat Neurosci 2000;3:587-592
    • (2000) Nat Neurosci , vol.3 , pp. 587-592
    • McKernan, R.M.1    Rosahl, T.W.2    Reynolds, D.S.3
  • 3
    • 0034613173 scopus 로고    scopus 로고
    • Molecular and neuronal substrate for the selective attenuation of anxiety
    • Löw K, Crestani F, Keist R, et al. Molecular and neuronal substrate for the selective attenuation of anxiety. Science 2000;290:131-134
    • (2000) Science , vol.290 , pp. 131-134
    • Löw, K.1    Crestani, F.2    Keist, R.3
  • 4
    • 0033592682 scopus 로고    scopus 로고
    • Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes
    • Rudolph U, Crestani F, Benke D, et al. Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes. Nature 1999;401: 796-800
    • (1999) Nature , vol.401 , pp. 796-800
    • Rudolph, U.1    Crestani, F.2    Benke, D.3
  • 6
    • 0032985617 scopus 로고    scopus 로고
    • Effects of GABA-transporter (GAT) inhibitors on rat behaviour in open-field and elevated plus-maze
    • Schmitt U, Hiemke C. Effects of GABA-transporter (GAT) inhibitors on rat behaviour in open-field and elevated plus-maze. Behav Pharmacol 1999;10: 131-137
    • (1999) Behav Pharmacol , vol.10 , pp. 131-137
    • Schmitt, U.1    Hiemke, C.2
  • 7
    • 0003318625 scopus 로고    scopus 로고
    • Adjunctive use of tiagabine with antidepressants in post-traumatic stress disorder
    • March 21-24; Austin, Tex
    • Lara ME. Adjunctive use of tiagabine with antidepressants in post-traumatic stress disorder. Presented at the 22nd National Conference of the Anxiety Disorders Association of America; March 21-24, 2002; Austin, Tex
    • (2002) 22nd National Conference of the Anxiety Disorders Association of America
    • Lara, M.E.1
  • 10
    • 0027365016 scopus 로고
    • Antidepressants for the treatment of generalized anxiety disorder: A placebo-controlled comparison of imipramine, trazodone, and diazepam
    • Rickels K, Downing R, Schweizer E, et al. Antidepressants for the treatment of generalized anxiety disorder: a placebo-controlled comparison of imipramine, trazodone, and diazepam. Arch Gen Psychiatry 1993;50: 884-895
    • (1993) Arch Gen Psychiatry , vol.50 , pp. 884-895
    • Rickels, K.1    Downing, R.2    Schweizer, E.3
  • 11
    • 0030908650 scopus 로고    scopus 로고
    • Paroxetine efficacy in the treatment of generalized anxiety disorder
    • Rocca P, Fonzo V, Scotta M, et al. Paroxetine efficacy in the treatment of generalized anxiety disorder. Acta Psychiatr Scand 1997;95:444-450
    • (1997) Acta Psychiatr Scand , vol.95 , pp. 444-450
    • Rocca, P.1    Fonzo, V.2    Scotta, M.3
  • 12
    • 0034965985 scopus 로고    scopus 로고
    • Paroxetine in the treatment of generalized anxiety disorder: Results of a placebo-controlled, flexibledosage trial
    • Pollack MH, Zaninelli R, Goddard A, et al. Paroxetine in the treatment of generalized anxiety disorder: results of a placebo-controlled, flexibledosage trial. J Clin Psychiatry 2001;62:350-357
    • (2001) J Clin Psychiatry , vol.62 , pp. 350-357
    • Pollack, M.H.1    Zaninelli, R.2    Goddard, A.3
  • 13
    • 0034044185 scopus 로고    scopus 로고
    • Efficacy of extended-release venlafaxine in nondepressed outpatients with generalized anxiety disorder
    • Rickels K, Pollack MH, Sheehan DV, et al. Efficacy of extended-release venlafaxine in nondepressed outpatients with generalized anxiety disorder. Am J Psychiatry 2000;157:968-974
    • (2000) Am J Psychiatry , vol.157 , pp. 968-974
    • Rickels, K.1    Pollack, M.H.2    Sheehan, D.V.3
  • 14
    • 0034697886 scopus 로고    scopus 로고
    • Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder: A 6-month controlled trial
    • Gelenberg AJ, Lydiard RB, Rudolph RL, et al. Efficacy of venlafaxine extended-release capsules in nondepressed outpatients with generalized anxiety disorder: a 6-month controlled trial. JAMA 2000;283:3082-3088
    • (2000) JAMA , vol.283 , pp. 3082-3088
    • Gelenberg, A.J.1    Lydiard, R.B.2    Rudolph, R.L.3
  • 15
    • 0037187193 scopus 로고    scopus 로고
    • 1A receptor acts during development to establish normal anxiety-like behavior in the adult
    • 1A receptor acts during development to establish normal anxiety-like behavior in the adult. Nature 2002;416:396-400
    • (2002) Nature , vol.416 , pp. 396-400
    • Gross, C.1    Zhuang, X.2    Stark, K.3
  • 16
    • 0032819491 scopus 로고    scopus 로고
    • Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors
    • Zhuang X, Gross C, Santarelli L, et al. Altered emotional states in knockout mice lacking 5-HT1A or 5-HT1B receptors. Neuropsychopharmacology 1999;21(2 suppl):52S-60S
    • (1999) Neuropsychopharmacology , vol.21 , Issue.2 SUPPL.
    • Zhuang, X.1    Gross, C.2    Santarelli, L.3
  • 17
    • 0032564431 scopus 로고    scopus 로고
    • Serotonin receptor 1A knockout: An animal model of anxiety-related disorder
    • Ramboz S, Oosting R, Amara DA, et al. Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proc Natl Acad Sci U S A 1998;95:14476-14481
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 14476-14481
    • Ramboz, S.1    Oosting, R.2    Amara, D.A.3
  • 18
    • 0012636049 scopus 로고    scopus 로고
    • Role of adult neurogenesis in the behavioral effect of antidepressant
    • Washington, DC: Society for Neuroscience. Program No. 102.8
    • Santarelli L, Saxe MD, Gross C, et al. Role of adult neurogenesis in the behavioral effect of antidepressant. In: 2002 Abstract Viewer/Itinerary Planner [CD-ROM]. Washington, DC: Society for Neuroscience, 2002. Program No. 102.8
    • (2002) 2002 Abstract Viewer/Itinerary Planner [CD-ROM]
    • Santarelli, L.1    Saxe, M.D.2    Gross, C.3
  • 19
    • 0034193435 scopus 로고    scopus 로고
    • Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: A functional MRI study
    • Rauch SL, Whalen PJ, Shin LM, et al. Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study. Biol Psychiatry 2000;47:769-776
    • (2000) Biol Psychiatry , vol.47 , pp. 769-776
    • Rauch, S.L.1    Whalen, P.J.2    Shin, L.M.3
  • 20
    • 0032550120 scopus 로고    scopus 로고
    • fMRI reveals amygdala activation to human faces in social phobics
    • Birbaumer N, Grodd W, Diedrich O, et al. fMRI reveals amygdala activation to human faces in social phobics. Neuroreport 1998;20:1223-1226
    • (1998) Neuroreport , vol.20 , pp. 1223-1226
    • Birbaumer, N.1    Grodd, W.2    Diedrich, O.3
  • 22
    • 0027353096 scopus 로고
    • The role of corticotropin-releasing factor in the pathophysiology of affective and anxiety disorders: Laboratory and clinical studies
    • discussion 308-316
    • Owens MJ, Nemeroff CB. The role of corticotropin-releasing factor in the pathophysiology of affective and anxiety disorders: laboratory and clinical studies. Ciba Found Symp 1993;172:296-308; discussion 308-316
    • (1993) Ciba Found Symp , vol.172 , pp. 296-308
    • Owens, M.J.1    Nemeroff, C.B.2
  • 23
    • 0031909215 scopus 로고    scopus 로고
    • Plasma cortisol concentrations preceding lactate-induced panic
    • Coplan JD, Goetz R, Klein DF, et al. Plasma cortisol concentrations preceding lactate-induced panic. Arch Gen Psychiatry 1998;55:130-136
    • (1998) Arch Gen Psychiatry , vol.55 , pp. 130-136
    • Coplan, J.D.1    Goetz, R.2    Klein, D.F.3
  • 24
    • 0031004906 scopus 로고    scopus 로고
    • Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder
    • Bremner JD, Licinio J, Darnell A, et al. Elevated CSF corticotropin-releasing factor concentrations in posttraumatic stress disorder. Am J Psychiatry 1997;154:624-629
    • (1997) Am J Psychiatry , vol.154 , pp. 624-629
    • Bremner, J.D.1    Licinio, J.2    Darnell, A.3
  • 25
    • 0035122647 scopus 로고    scopus 로고
    • The anxiolytic effects of the CRH(1) receptor antagonist R121919 depends on innate emotionality in rats
    • Keck ME, Welt T, Wigger A, et al. The anxiolytic effects of the CRH(1) receptor antagonist R121919 depends on innate emotionality in rats. Eur J Neurosci 2001;13:373-380
    • (2001) Eur J Neurosci , vol.13 , pp. 373-380
    • Keck, M.E.1    Welt, T.2    Wigger, A.3
  • 26
    • 0034193881 scopus 로고    scopus 로고
    • Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: The first 20 patients treated
    • Zobel AW, Nickel T, Kunzel HE, et al. Effects of the high-affinity corticotropin-releasing hormone receptor 1 antagonist R121919 in major depression: the first 20 patients treated. J Psychiatr Res 2000;34:171-181
    • (2000) J Psychiatr Res , vol.34 , pp. 171-181
    • Zobel, A.W.1    Nickel, T.2    Kunzel, H.E.3
  • 27
    • 0021255570 scopus 로고
    • Substance P receptors: Localization by light microscopic autoradiography in rat brain using [3H]SP as the radioligand
    • Mantyh PW, Hunt SP, Maggio JE. Substance P receptors: localization by light microscopic autoradiography in rat brain using [3H]SP as the radioligand. Brain Res 1984;307(1-2):147-165
    • (1984) Brain Res , vol.307 , Issue.1-2 , pp. 147-165
    • Mantyh, P.W.1    Hunt, S.P.2    Maggio, J.E.3
  • 28
    • 0023758981 scopus 로고
    • Substance P induces a cardiovascular defense reaction in the rat: Pharmacological characterization
    • Unger T, Carolus S, Demmert G, et al. Substance P induces a cardiovascular defense reaction in the rat: pharmacological characterization. Circ Res 1988;63:12-20
    • (1988) Circ Res , vol.63 , pp. 12-20
    • Unger, T.1    Carolus, S.2    Demmert, G.3
  • 29
    • 0028067379 scopus 로고
    • Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats
    • Krase W, Koch M, Schilitzler HU. Substance P is involved in the sensitization of the acoustic startle response by footshocks in rats. Behav Brain Res 1994;63:81-88
    • (1994) Behav Brain Res , vol.63 , pp. 81-88
    • Krase, W.1    Koch, M.2    Schilitzler, H.U.3
  • 30
    • 0035218323 scopus 로고    scopus 로고
    • Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1) receptor in assays for antidepressant and anxiolytic drugs
    • Rupniak NM, Carlson EJ, Webb JK, et al. Comparison of the phenotype of NK1R-/- mice with pharmacological blockade of the substance P (NK1) receptor in assays for antidepressant and anxiolytic drugs. Behav Pharmacol 2001;12(6-7):497-508
    • (2001) Behav Pharmacol , vol.12 , Issue.6-7 , pp. 497-508
    • Rupniak, N.M.1    Carlson, E.J.2    Webb, J.K.3
  • 31
    • 0033833835 scopus 로고    scopus 로고
    • The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats
    • Papp M, Vassout A, Gentsch C. The NK1-receptor antagonist NKP608 has an antidepressant-like effect in the chronic mild stress model of depression in rats. Behav Brain Res 2000;115:19-23
    • (2000) Behav Brain Res , vol.115 , pp. 19-23
    • Papp, M.1    Vassout, A.2    Gentsch, C.3
  • 32
    • 0032508514 scopus 로고    scopus 로고
    • Distinct mechanism for antidepressant activity by blockade of central substance P receptors
    • Kramer MS, Cutler N, Feighner J, et al. Distinct mechanism for antidepressant activity by blockade of central substance P receptors. Science 1998; 281:1640-1645
    • (1998) Science , vol.281 , pp. 1640-1645
    • Kramer, M.S.1    Cutler, N.2    Feighner, J.3
  • 34
    • 0027518699 scopus 로고
    • Evidence for benzodiazepine receptor interaction with MK 801 in anxiety related behavior in rats
    • Sharma AC, Kulkarni SK. Evidence for benzodiazepine receptor interaction with MK 801 in anxiety related behavior in rats. Indian J Exp Biol 1993;31:191-193
    • (1993) Indian J Exp Biol , vol.31 , pp. 191-193
    • Sharma, A.C.1    Kulkarni, S.K.2
  • 35
    • 0026591806 scopus 로고
    • Anxiolytic-like effects of the noncompetitive NMDA antagonist MK 801
    • Xie Z, Commissaris RL. Anxiolytic-like effects of the noncompetitive NMDA antagonist MK 801. Pharmacol Biochem Behav 1992;43:471-477
    • (1992) Pharmacol Biochem Behav , vol.43 , pp. 471-477
    • Xie, Z.1    Commissaris, R.L.2
  • 36
    • 0025157918 scopus 로고
    • Functional antagonists at the NMDA receptor complex exhibit antidepressant actions
    • Trullas R, Skolnick P. Functional antagonists at the NMDA receptor complex exhibit antidepressant actions. Eur J Pharmacol 1990;185:1-10
    • (1990) Eur J Pharmacol , vol.185 , pp. 1-10
    • Trullas, R.1    Skolnick, P.2
  • 37
    • 0027817396 scopus 로고
    • New evidence for the antidepressant activity of MK-801, a non-competitive antagonist of NMDA receptors
    • Papp M, Moryl E. New evidence for the antidepressant activity of MK-801, a non-competitive antagonist of NMDA receptors. Pol J Pharmacol 1993; 45:549-553
    • (1993) Pol J Pharmacol , vol.45 , pp. 549-553
    • Papp, M.1    Moryl, E.2
  • 38
    • 0343052958 scopus 로고    scopus 로고
    • Antidepressant-like effects of a partial agonist at strychnine-insensitive glycine receptors and a competitive NMDA receptor antagonist
    • Przegalinski E, Tatarczynska E, Deren-Wesolek A, et al. Antidepressant-like effects of a partial agonist at strychnine-insensitive glycine receptors and a competitive NMDA receptor antagonist. Neuropharmacology 1997; 36:31-37
    • (1997) Neuropharmacology , vol.36 , pp. 31-37
    • Przegalinski, E.1    Tatarczynska, E.2    Deren-Wesolek, A.3
  • 39
    • 0033969685 scopus 로고    scopus 로고
    • Antidepressant effects of ketamine in depressed patients
    • Berman RM, Cappiello A, Anand A, et al. Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 2000;47:351-354
    • (2000) Biol Psychiatry , vol.47 , pp. 351-354
    • Berman, R.M.1    Cappiello, A.2    Anand, A.3
  • 40
    • 0032983086 scopus 로고    scopus 로고
    • Antidepressants for the new millennium
    • Skolnick P. Antidepressants for the new millennium. Eur J Pharmacol 1999;375:31-40
    • (1999) Eur J Pharmacol , vol.375 , pp. 31-40
    • Skolnick, P.1
  • 41
    • 0034100686 scopus 로고    scopus 로고
    • LY354740, a potent group II metabotropic glutamate receptor agonist prevents lactate-induced panic-like response in panic-prone rats
    • Shekhar A, Keim SR. LY354740, a potent group II metabotropic glutamate receptor agonist prevents lactate-induced panic-like response in panic-prone rats. Neuropharmacology 2000;39:1139-1146
    • (2000) Neuropharmacology , vol.39 , pp. 1139-1146
    • Shekhar, A.1    Keim, S.R.2
  • 42
    • 0034874749 scopus 로고    scopus 로고
    • Effects of LY354740, a novel glutamatergic metabotropic agonist, on nonhuman primate hypothalamic-pituitary adrenal and noradrenergic function
    • Coplan JD, Smith E, Trost R, et al. Effects of LY354740, a novel glutamatergic metabotropic agonist, on nonhuman primate hypothalamic-pituitary adrenal and noradrenergic function. CNS Spectrums 2001;6:607-617
    • (2001) CNS Spectrums , vol.6 , pp. 607-617
    • Coplan, J.D.1    Smith, E.2    Trost, R.3
  • 43
    • 0031807049 scopus 로고    scopus 로고
    • Case study: Caudate glutamatergic changes with paroxetine therapy for pediatric obsessive-compulsive disorder
    • Moore GJ, MacMaster FP, Stewart C, et al. Case study: caudate glutamatergic changes with paroxetine therapy for pediatric obsessive-compulsive disorder. J Am Acad Child Adolesc Psychiatry 1998;37:663-667
    • (1998) J Am Acad Child Adolesc Psychiatry , vol.37 , pp. 663-667
    • Moore, G.J.1    MacMaster, F.P.2    Stewart, C.3
  • 44
    • 0037092425 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression
    • Shirayama Y, Chen AC, Nakagawa S, et al. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J Neurosci 2002;22:3251-3261
    • (2002) J Neurosci , vol.22 , pp. 3251-3261
    • Shirayama, Y.1    Chen, A.C.2    Nakagawa, S.3
  • 45
    • 0035881828 scopus 로고    scopus 로고
    • Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
    • Chen B, Dowlatshahi D, MacQueen GM, et al. Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication. Biol Psychiatry 2001;50:260-265
    • (2001) Biol Psychiatry , vol.50 , pp. 260-265
    • Chen, B.1    Dowlatshahi, D.2    MacQueen, G.M.3


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