Definition of an uptake pharmacophore of the serotonin transporter through 3D-QSAR analysis

Current Medicinal Chemistry

Volumn 12, Issue 20, 2005, Pages 2393-2410

  Pratuangdejkul, J ^a,b,i   Schneider, B ^c,j   Jaudon, P ^d   Rosilio, V ^e   Baudoin, E ^f   Loric, S ^g   Conti, M ^h   Launay, J M ^a,b   Manivet, P ^a,b  

^a HÔPITAL LARIBOISIÈRE   (France)

^b Laboratoire de Biologie Cellulaire   (France)

^c INSTITUT ANDRÉ LWOFF   (France)

^d UNIVERSITÉ PARIS SACLAY   (France)

^e UNIV PARIS SUD   (France)

^f BioQuanta   (France)

^g HENRI MONDOR HOSPITAL   (France)

^h BICÊTRE HOSPITAL   (France)

ⁱ MAHIDOL UNIVERSITY   (Thailand)

^j INSTITUT PASTEUR   (France)

more..

Author keywords

3D; 5 HT; 5 hydorxytryptamine; Pharmacophore; QSAR; Quantitavie structure activity relationships; Serotonin transporter; SERT; Three dimentional

Indexed keywords

4 HYDROXY 3 METHOXYMETHAMPHATAMINE; AMPHETAMINE DERIVATIVE; BENZOTHIAZOLE DERIVATIVE; FENFLURAMINE; HARMAN; INDANONE DERIVATIVE; NORFENFLURAMINE; PHENTERMINE; PIPERAZINE DERIVATIVE; SEROTONIN; SEROTONIN TRANSPORTER; UNCLASSIFIED DRUG;

ADULT; CELL MEMBRANE; CONCENTRATION (PARAMETERS); CONFORMATIONAL TRANSITION; CYTOTOXICITY; DRUG TARGETING; HOMEOSTASIS; HUMAN; HUMAN CELL; MALE; MENTAL DISEASE; METABOLIC DISORDER; MOLECULAR DYNAMICS; PHARMACOPHORE; PROTEIN TARGETING; PROTEIN TRANSPORT; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM CHEMISTRY; REGULATORY MECHANISM; RELIABILITY; REVIEW; SEROTONINERGIC SYSTEM; STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

EID: 24944468298     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/0929867054864813     Document Type: Review

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