-
1
-
-
0035122827
-
Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition
-
Adkins EM, Barker EL, and Blakely RD (2001) Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition. Mol Pharmacol 59:514-523.
-
(2001)
Mol Pharmacol
, vol.59
, pp. 514-523
-
-
Adkins, E.M.1
Barker, E.L.2
Blakely, R.D.3
-
2
-
-
0026614687
-
[3H] cocaine labels a binding site associated with the serotonin transporter in guinea pig brain: Allosteric modulation by paroxetine
-
Akunne HC, de Costa BR, Jacobson AE, Rice KC, and Rothman RB (1992) [3H] cocaine labels a binding site associated with the serotonin transporter in guinea pig brain: allosteric modulation by paroxetine. Neurochem Res 17:1275-1283.
-
(1992)
Neurochem Res
, vol.17
, pp. 1275-1283
-
-
Akunne, H.C.1
De Costa, B.R.2
Jacobson, A.E.3
Rice, K.C.4
Rothman, R.B.5
-
3
-
-
0032893084
-
The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1999
-
Bairoch A and Apweiler R (1999) The SWISS-PROT protein sequence data bank and its supplement TrEMBL in 1999. Nucleic Acids Res 27:49-54.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 49-54
-
-
Bairoch, A.1
Apweiler, R.2
-
4
-
-
0000358207
-
Norepinephrine and serotonin transporters: Molecular targets of antidepressant drugs
-
(Bloom FE and Kupfer DJ eds), Raven Press, New York
-
Barker EL and Blakely RD (1995). Norepinephrine and serotonin transporters: molecular targets of antidepressant drugs, in Psychopharmacology: The Fourth Generation of Progress (Bloom FE and Kupfer DJ eds) pp 321-334, Raven Press, New York.
-
(1995)
Psychopharmacology: The Fourth Generation of Progress
, pp. 321-334
-
-
Barker, E.L.1
Blakely, R.D.2
-
5
-
-
0033564765
-
Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter
-
Barker EL, Moore KR, Rakhshan F, and Blakely RD (1999) Transmembrane domain I contributes to the permeation pathway for serotonin and ions in the serotonin transporter. J Neurosci 19:4705-4717.
-
(1999)
J Neurosci
, vol.19
, pp. 4705-4717
-
-
Barker, E.L.1
Moore, K.R.2
Rakhshan, F.3
Blakely, R.D.4
-
6
-
-
0032584587
-
High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol
-
Barker EL, Perlman MA, Adkins EM, Houlihan WJ, Pristupa ZB, Niznik HB, and Blakely RD (1998) High affinity recognition of serotonin transporter antagonists defined by species-scanning mutagenesis. An aromatic residue in transmembrane domain I dictates species-selective recognition of citalopram and mazindol. J Biol Chem 273:19459-19468.
-
(1998)
J Biol Chem
, vol.273
, pp. 19459-19468
-
-
Barker, E.L.1
Perlman, M.A.2
Adkins, E.M.3
Houlihan, W.J.4
Pristupa, Z.B.5
Niznik, H.B.6
Blakely, R.D.7
-
7
-
-
0033954256
-
The Protein Data Bank
-
Berman HM, Westbrook J, Feng Z, Gilliland G, Bhat TN, Weissig H, Shindyalov IN, and Bourne PE (2000) The Protein Data Bank. Nucleic Acids Res 28:235-242.
-
(2000)
Nucleic Acids Res
, vol.28
, pp. 235-242
-
-
Berman, H.M.1
Westbrook, J.2
Feng, Z.3
Gilliland, G.4
Bhat, T.N.5
Weissig, H.6
Shindyalov, I.N.7
Bourne, P.E.8
-
8
-
-
0035823075
-
Structure of MsbA from E. coli: A homolog of the multidrug resistance ATP binding cassette (ABC) transporters
-
Chang G and Roth CB (2001) Structure of MsbA from E. coli: a homolog of the multidrug resistance ATP binding cassette (ABC) transporters. Science (Wash DC) 293:1793-1800.
-
(2001)
Science (Wash DC)
, vol.293
, pp. 1793-1800
-
-
Chang, G.1
Roth, C.B.2
-
9
-
-
0032524637
-
Determination of external loop topology in the serotonin transporter by site-directed chemical labeling
-
Chen JG, Liu-Chen S, and Rudnick G (1998) Determination of external loop topology in the serotonin transporter by site-directed chemical labeling. J Biol Chem 273:12675-12681.
-
(1998)
J Biol Chem
, vol.273
, pp. 12675-12681
-
-
Chen, J.G.1
Liu-Chen, S.2
Rudnick, G.3
-
10
-
-
0030692041
-
The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding
-
Chen JG, Sachpatzidis A, and Rudnick G (1997) The third transmembrane domain of the serotonin transporter contains residues associated with substrate and cocaine binding. J Biol Chem 272:28321-28327.
-
(1997)
J Biol Chem
, vol.272
, pp. 28321-28327
-
-
Chen, J.G.1
Sachpatzidis, A.2
Rudnick, G.3
-
11
-
-
0029011701
-
A 2nd generation force-field for the simulation of proteins, nucleic-acids and organic-molecules
-
Cornell WD, Cieplak P, Bayly CI, Gould IR, Merz KM, Ferguson DM, Spellmeyer DC, Fox T, Caldwell JW, and Kollman PA (1995) A 2nd generation force-field for the simulation of proteins, nucleic-acids and organic-molecules. J Am Chem Soc 117:5179-5197.
-
(1995)
J Am Chem Soc
, vol.117
, pp. 5179-5197
-
-
Cornell, W.D.1
Cieplak, P.2
Bayly, C.I.3
Gould, I.R.4
Merz, K.M.5
Ferguson, D.M.6
Spellmeyer, D.C.7
Fox, T.8
Caldwell, J.W.9
Kollman, P.A.10
-
13
-
-
0025881062
-
Three-dimensional models of neurotransmitter G-binding protein-coupled receptors
-
Hibert MF, Trumpp-Kallmeyer S, Bruinvels A, and Hoflack J (1991) Three-dimensional models of neurotransmitter G-binding protein-coupled receptors. Mol Pharmacol 40:8-15.
-
(1991)
Mol Pharmacol
, vol.40
, pp. 8-15
-
-
Hibert, M.F.1
Trumpp-Kallmeyer, S.2
Bruinvels, A.3
Hoflack, J.4
-
14
-
-
0028294525
-
Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs)
-
Hyttel J (1994) Pharmacological characterization of selective serotonin reuptake inhibitors (SSRIs). Int Clin Psychopharmacol 9 (Suppl 1):19-26.
-
(1994)
Int Clin Psychopharmacol
, vol.9
, Issue.SUPPL. 1
, pp. 19-26
-
-
Hyttel, J.1
-
15
-
-
0031398840
-
From membrane to molecule to the third amino acid from the left with a membrane transport protein
-
Kaback HR and Wu J (1997) From membrane to molecule to the third amino acid from the left with a membrane transport protein. Q Rev Biophys 30:333-364.
-
(1997)
Q Rev Biophys
, vol.30
, pp. 333-364
-
-
Kaback, H.R.1
Wu, J.2
-
17
-
-
0036725277
-
Molecular dynamics simulations of biomolecules
-
Karplus M and McCammon JA (2002) Molecular dynamics simulations of biomolecules. Nat Struct Biol 9:646-652.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 646-652
-
-
Karplus, M.1
McCammon, J.A.2
-
18
-
-
0030608258
-
Dissection of dopamine and cocaine binding sites on the rat dopamine transporter expressed in COS cells
-
Kitayama S, Morita K, Dohi T, Wang JB, Davis SC, and Uhl GR (1996) Dissection of dopamine and cocaine binding sites on the rat dopamine transporter expressed in COS cells. Ann N Y Acad Sci 801:388-393.
-
(1996)
Ann N Y Acad Sci
, vol.801
, pp. 388-393
-
-
Kitayama, S.1
Morita, K.2
Dohi, T.3
Wang, J.B.4
Davis, S.C.5
Uhl, G.R.6
-
19
-
-
0026722234
-
Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding
-
Kitayama S, Shimada S, Xu H, Markham L, Donovan DM, and Uhl GR (1992) Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. Proc Natl Acad Sci USA 89:7782-7785.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 7782-7785
-
-
Kitayama, S.1
Shimada, S.2
Xu, H.3
Markham, L.4
Donovan, D.M.5
Uhl, G.R.6
-
20
-
-
0036142190
-
Crystal structure of a bacterial cocaine esterase
-
Larsen NA, Turner JM, Stevens J, Rosser SJ, Basran A, Lerner RA, Bruce NC, and Wilson IA (2002) Crystal structure of a bacterial cocaine esterase. Nat Struct Biol 9:17-21.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 17-21
-
-
Larsen, N.A.1
Turner, J.M.2
Stevens, J.3
Rosser, S.J.4
Basran, A.5
Lerner, R.A.6
Bruce, N.C.7
Wilson, I.A.8
-
21
-
-
0034015391
-
Importance of valine at position 152 for the substrate transport and 2β-carbomethoxy-3β-(4-fluorophenyl)tropane binding of dopamine transporter
-
Lee SH, Chang MY, Lee KH, Park BS, Lee YS, and Chin HR (2000) Importance of valine at position 152 for the substrate transport and 2β -carbomethoxy-3β-(4-fluorophenyl)tropane binding of dopamine transporter. Mol Pharmacol 57:883-889.
-
(2000)
Mol Pharmacol
, vol.57
, pp. 883-889
-
-
Lee, S.H.1
Chang, M.Y.2
Lee, K.H.3
Park, B.S.4
Lee, Y.S.5
Chin, H.R.6
-
22
-
-
0032801143
-
Dopamine transporter: Transmembrane phenylalanine mutations can selectively influence dopamine uptake and cocaine analog recognition
-
Lin Z, Wang W, Kopajtic T, Revay RS, and Uhl GR (1999) Dopamine transporter: transmembrane phenylalanine mutations can selectively influence dopamine uptake and cocaine analog recognition. Mol Pharmacol 56:434-447.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 434-447
-
-
Lin, Z.1
Wang, W.2
Kopajtic, T.3
Revay, R.S.4
Uhl, G.R.5
-
23
-
-
0032078412
-
Tyrosine-533 of rat dopamine transporter: Involvement in interactions with 1-methyl-4-phenylpyridinium and cocaine
-
Mitsuhata C, Kitayama S, Morita K, Vandenbergh D, Uhl GR, and Dohi T (1998) Tyrosine-533 of rat dopamine transporter: involvement in interactions with 1-methyl-4-phenylpyridinium and cocaine. Brain Res Mol Brain Res 56:84-88.
-
(1998)
Brain Res Mol Brain Res
, vol.56
, pp. 84-88
-
-
Mitsuhata, C.1
Kitayama, S.2
Morita, K.3
Vandenbergh, D.4
Uhl, G.R.5
Dohi, T.6
-
24
-
-
0034780661
-
Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants
-
Mortensen OV, Kristensen AS, and Wiborg O (2001) Species-scanning mutagenesis of the serotonin transporter reveals residues essential in selective, high-affinity recognition of antidepressants. J Neurochem 79:237-247.
-
(2001)
J Neurochem
, vol.79
, pp. 237-247
-
-
Mortensen, O.V.1
Kristensen, A.S.2
Wiborg, O.3
-
26
-
-
0035450364
-
Second-generation SSRIs: Human monoamine transporter binding profile of escitalopram and R-fluoxetine
-
Owens MJ, Knight DL, and Nemeroff CB (2001) Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine. Biol Psychiatry 50:345-350.
-
(2001)
Biol Psychiatry
, vol.50
, pp. 345-350
-
-
Owens, M.J.1
Knight, D.L.2
Nemeroff, C.B.3
-
27
-
-
0035900878
-
Tyrosine residue 271 of the norepinephrine transporter is an important determinant of its pharmacology
-
Paczkowski FA and Bryan-Lluka LJ (2001) Tyrosine residue 271 of the norepinephrine transporter is an important determinant of its pharmacology. Brain Res Mol Brain Res 97:32-42.
-
(2001)
Brain Res Mol Brain Res
, vol.97
, pp. 32-42
-
-
Paczkowski, F.A.1
Bryan-Lluka, L.J.2
-
28
-
-
0034604451
-
Crystal structure of rhodopsin: A G protein-coupled receptor
-
Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, Fox BA, Le Trong I, Teller DC, Okada T, Stenkamp RE, Yamamoto M, and Miyano M (2000) Crystal structure of rhodopsin: a G protein-coupled receptor. Science (Wash DC) 289:739-745.
-
(2000)
Science (Wash DC)
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
Le Trong, I.7
Teller, D.C.8
Okada, T.9
Stenkamp, R.E.10
Yamamoto, M.11
Miyano, M.12
-
29
-
-
0032561347
-
Critical amino acid residues in transmembrane span 7 of the serotonin transporter identified by random mutagenesis
-
Penado KM, Rudnick G, and Stephan MM (1998) Critical amino acid residues in transmembrane span 7 of the serotonin transporter identified by random mutagenesis. J Biol Chem 273:28098-28106.
-
(1998)
J Biol Chem
, vol.273
, pp. 28098-28106
-
-
Penado, K.M.1
Rudnick, G.2
Stephan, M.M.3
-
30
-
-
0027405191
-
Antidepressant- and cocaine-sensitive human serotonin transporter: Molecular cloning, expression and chromosomal localization
-
Ramamoorthy S, Bauman AL, Moore KR, Han H, Yang-Feng T, Chang AS, Ganapathy V, and Blakely RD (1993) Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression and chromosomal localization. Proc Natl Acad Sci USA 90:2542-2546.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 2542-2546
-
-
Ramamoorthy, S.1
Bauman, A.L.2
Moore, K.R.3
Han, H.4
Yang-Feng, T.5
Chang, A.S.6
Ganapathy, V.7
Blakely, R.D.8
-
31
-
-
0035895969
-
Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter
-
Rasmussen SG, Carroll FI, Maresch MJ, Jensen AD, Tate CG, and Gether U (2001) Biophysical characterization of the cocaine binding pocket in the serotonin transporter using a fluorescent cocaine analogue as a molecular reporter. J Biol Chem 276:4717-4723.
-
(2001)
J Biol Chem
, vol.276
, pp. 4717-4723
-
-
Rasmussen, S.G.1
Carroll, F.I.2
Maresch, M.J.3
Jensen, A.D.4
Tate, C.G.5
Gether, U.6
-
32
-
-
0035195373
-
A putative three-dimensional arrangement of the human serotonin transporter transmembrane helices: A tool to aid experimental studies
-
Ravna AW and Edvardsen O (2001) A putative three-dimensional arrangement of the human serotonin transporter transmembrane helices: a tool to aid experimental studies. J Mol Graph Model 20:133-144.
-
(2001)
J Mol Graph Model
, vol.20
, pp. 133-144
-
-
Ravna, A.W.1
Edvardsen, O.2
-
37
-
-
0031746091
-
Distinct effects of imipramine on 5-hydroxytryptamine uptake mediated by the recombinant rat serotonin transporter SERT1
-
Sur C, Betz H, and Schloss P (1998) Distinct effects of imipramine on 5-hydroxytryptamine uptake mediated by the recombinant rat serotonin transporter SERT1. J Neurochem 70:2545-2553.
-
(1998)
J Neurochem
, vol.70
, pp. 2545-2553
-
-
Sur, C.1
Betz, H.2
Schloss, P.3
-
39
-
-
0031565115
-
Pharmacological profile of antidepressants and related compounds at human monoamine transporters
-
Tatsumi M, Groshan K, Blakely RD, and Richelson E (1997) Pharmacological profile of antidepressants and related compounds at human monoamine transporters. Eur J Pharmacol 340:249-258.
-
(1997)
Eur J Pharmacol
, vol.340
, pp. 249-258
-
-
Tatsumi, M.1
Groshan, K.2
Blakely, R.D.3
Richelson, E.4
-
40
-
-
0034610788
-
Three-dimensional structure of the ion-coupled transport protein NhaA
-
Williams KA (2000) Three-dimensional structure of the ion-coupled transport protein NhaA. Nature (Lond) 403:112-115.
-
(2000)
Nature (Lond)
, vol.403
, pp. 112-115
-
-
Williams, K.A.1
|