A strategy for the incorporation of water molecules present in a ligand binding site into a three-dimensional quantitative structure - Activity relationship analysis

Journal of Medicinal Chemistry

Volumn 40, Issue 25, 1997, Pages 4089-4102

  Pastor, Manuel ^a   Cruciani, Gabriele ^b   Watson, Kimberly A ^c  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b UNIVERSITY OF PERUGIA   (Italy)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

WATER;

ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG DESIGN; DRUG PROTEIN BINDING; STRUCTURE ACTIVITY RELATION;

BINDING SITES; DRUG DESIGN; ENZYME INHIBITORS; MODELS, STRUCTURAL; PHOSPHORYLASES; STRUCTURE-ACTIVITY RELATIONSHIP; WATER;

EID: 0031442549     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970273d     Document Type: Article

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