-
1
-
-
0029985369
-
Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway
-
Biederer T, Volkwein C, Sommer T. 1996. Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway. EMBO J. 15:2069-76
-
(1996)
EMBO J.
, vol.15
, pp. 2069-2076
-
-
Biederer, T.1
Volkwein, C.2
Sommer, T.3
-
2
-
-
0030666729
-
Role of Cue1p in ubiquitination and degradation at the ER surface
-
Biederer T, Volkwein C, Sommer T. 1997. Role of Cue1p in ubiquitination and degradation at the ER surface. Science 278:1806-9
-
(1997)
Science
, vol.278
, pp. 1806-1809
-
-
Biederer, T.1
Volkwein, C.2
Sommer, T.3
-
3
-
-
0037084028
-
Role of the ubiquitin-selective CDC48 chaperone in ERAD of OLE1 and other substrates
-
Braun S, Matuschewski K, Rape M, Thoms S, Jentsch S. 2002. Role of the ubiquitin-selective CDC48 chaperone in ERAD of OLE1 and other substrates. EMBO J. 21:615-21
-
(2002)
EMBO J.
, vol.21
, pp. 615-621
-
-
Braun, S.1
Matuschewski, K.2
Rape, M.3
Thoms, S.4
Jentsch, S.5
-
4
-
-
0033208984
-
ER protein quality control and proteasome-mediated protein degradation
-
Brodsky JL, McCracken AA. 1999. ER protein quality control and proteasome-mediated protein degradation. Semin. Cell Dev. Biol. 10:507-13
-
(1999)
Semin. Cell Dev. Biol.
, vol.10
, pp. 507-513
-
-
Brodsky, J.L.1
McCracken, A.A.2
-
5
-
-
0035968205
-
Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi
-
Caldwell SR, Hill KJ, Cooper AA. 2001. Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and Golgi. J. Biol. Chem. 276:23296-303
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 23296-23303
-
-
Caldwell, S.R.1
Hill, K.J.2
Cooper, A.A.3
-
6
-
-
4544232744
-
The DeltaF508 mutation disrupts packing of the transmembrane segments of the cystic fibrosis transmembrane conductance regulator
-
Chen EY, Bartlett MC, Loo TW, Clarke DM. 2004. The DeltaF508 mutation disrupts packing of the transmembrane segments of the cystic fibrosis transmembrane conductance regulator. J. Biol. Chem. 279:39620-27
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 39620-39627
-
-
Chen, E.Y.1
Bartlett, M.C.2
Loo, T.W.3
Clarke, D.M.4
-
7
-
-
0033957668
-
Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity
-
Chillaron J, Haas IG. 2000. Dissociation from BiP and retrotranslocation of unassembled immunoglobulin light chains are tightly coupled to proteasome activity. Mol. Biol. Cell. 11:217-26
-
(2000)
Mol. Biol. Cell
, vol.11
, pp. 217-226
-
-
Chillaron, J.1
Haas, I.G.2
-
8
-
-
0034611014
-
Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p
-
Cronin SR, Khoury A, Ferry DK, Hampton RY. 2000. Regulation of HMG-CoA reductase degradation requires the P-type ATPase Cod1p/Spf1p. J. Cell. Biol. 148:915-24
-
(2000)
J. Cell. Biol.
, vol.148
, pp. 915-924
-
-
Cronin, S.R.1
Khoury, A.2
Ferry, D.K.3
Hampton, R.Y.4
-
10
-
-
0034907973
-
Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation
-
Dai RM, Li CC. 2001. Valosin-containing protein is a multi-ubiquitin chain-targeting factor required in ubiquitin-proteasome degradation. Nat. Cell. Biol. 3:740-74
-
(2001)
Nat. Cell. Biol.
, vol.3
, pp. 740-774
-
-
Dai, R.M.1
Li, C.C.2
-
11
-
-
0031664331
-
2+ required for glycosylation, sorting, and endoplasmic reticulum-associated protein degradation
-
2+ required for glycosylation, sorting, and endoplasmic reticulum-associated protein degradation. Mol. Biol. Cell. 9:1149-62
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 1149-1162
-
-
Durr, G.1
Strayle, J.2
Plemper, R.3
Elbs, S.4
Klee, S.K.5
-
12
-
-
0036115199
-
Calcium-pump inhibitors induce functional surface expression of delta F508-CFTR protein in cystic fibrosis epithelial cells
-
Egan ME, Glockner-Pagel J, Ambrose C, Cahill PA, Pappoe L, et al. 2002. Calcium-pump inhibitors induce functional surface expression of delta F508-CFTR protein in cystic fibrosis epithelial cells. Nat. Med. 8:485-92
-
(2002)
Nat. Med.
, vol.8
, pp. 485-492
-
-
Egan, M.E.1
Glockner-Pagel, J.2
Ambrose, C.3
Cahill, P.A.4
Pappoe, L.5
-
13
-
-
0036713383
-
Proteasome subunit Rpn1 binds ubiquitin-like domains
-
Elsasser S, Gali RR, Schwickart M, Larsen CN, Leggett DS, et al. 2002. Proteasome subunit Rpn1 binds ubiquitin-like domains. Nat. Cell. Biol. 4:725-30
-
(2002)
Nat. Cell. Biol.
, vol.4
, pp. 725-730
-
-
Elsasser, S.1
Gali, R.R.2
Schwickart, M.3
Larsen, C.N.4
Leggett, D.S.5
-
14
-
-
0032476655
-
Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast
-
Enenkel C, Lehmann A, Kloetzel PM. 1998. Subcellular distribution of proteasomes implicates a major location of protein degradation in the nuclear envelope-ER network in yeast. EMBO J. 17:6144-54
-
(1998)
EMBO J.
, vol.17
, pp. 6144-6154
-
-
Enenkel, C.1
Lehmann, A.2
Kloetzel, P.M.3
-
15
-
-
0035798550
-
Reduction of interchain disulfide bonds precedes the dislocation of Ig-mu chains from the endoplasmic reticulum to the cytosol for proteasomal degradation
-
Fagioli C, Mezghrani A, Sitia R. 2001. Reduction of interchain disulfide bonds precedes the dislocation of Ig-mu chains from the endoplasmic reticulum to the cytosol for proteasomal degradation. J. Biol. Chem. 276:40962-67
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 40962-40967
-
-
Fagioli, C.1
Mezghrani, A.2
Sitia, R.3
-
16
-
-
1642505493
-
Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin
-
Fiebiger E, Hirsch C, Vyas JM, Gordon E, Ploegh HL, Tortorella D. 2004. Dissection of the dislocation pathway for type I membrane proteins with a new small molecule inhibitor, eeyarestatin. Mol. Biol. Cell. 15:1635-46
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 1635-1646
-
-
Fiebiger, E.1
Hirsch, C.2
Vyas, J.M.3
Gordon, E.4
Ploegh, H.L.5
Tortorella, D.6
-
17
-
-
0036499973
-
Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein
-
Fiebiger E, Story C, Ploegh HL, Tortorella D. 2002. Visualization of the ER-to-cytosol dislocation reaction of a type I membrane protein. EMBO J. 21:1041-53
-
(2002)
EMBO J.
, vol.21
, pp. 1041-1053
-
-
Fiebiger, E.1
Story, C.2
Ploegh, H.L.3
Tortorella, D.4
-
18
-
-
0029881380
-
A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae
-
Finke K, Plath K, Panzner S, Prehn S, Rapoport TA, et al. 1996. A second trimeric complex containing homologs of the Sec61p complex functions in protein transport across the ER membrane of S. cerevisiae. EMBO J. 15:1482-94
-
(1996)
EMBO J.
, vol.15
, pp. 1482-1494
-
-
Finke, K.1
Plath, K.2
Panzner, S.3
Prehn, S.4
Rapoport, T.A.5
-
19
-
-
0041315902
-
Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane
-
Flierman D, Ye Y, Dai M, Chau V, Rapoport TA. 2003. Polyubiquitin serves as a recognition signal, rather than a ratcheting molecule, during retrotranslocation of proteins across the endoplasmic reticulum membrane. J. Biol. Chem. 278:34774-82
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 34774-34782
-
-
Flierman, D.1
Ye, Y.2
Dai, M.3
Chau, V.4
Rapoport, T.A.5
-
20
-
-
0026059137
-
Peptide-binding specificity of the molecular chaperone BiP
-
Flynn GC, Pohl J, Flocco MT, Rothman JE. 1991. Peptide-binding specificity of the molecular chaperone BiP. Nature 353:726-30
-
(1991)
Nature
, vol.353
, pp. 726-730
-
-
Flynn, G.C.1
Pohl, J.2
Flocco, M.T.3
Rothman, J.E.4
-
21
-
-
0037455585
-
Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulator
-
Fu L, Sztul E. 2003. Traffic-independent function of the Sar1p/COPII machinery in proteasomal sorting of the cystic fibrosis transmembrane conductance regulator. J. Cell. Biol. 160:157-63
-
(2003)
J. Cell. Biol.
, vol.160
, pp. 157-163
-
-
Fu, L.1
Sztul, E.2
-
22
-
-
0033231014
-
A 'distributed degron' allows regulated entry into the ER degradation pathway
-
Gardner RG, Hampton RY. 1999. A 'distributed degron' allows regulated entry into the ER degradation pathway. EMBO J. 18:5994-6004
-
(1999)
EMBO J.
, vol.18
, pp. 5994-6004
-
-
Gardner, R.G.1
Hampton, R.Y.2
-
23
-
-
0033611127
-
Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase
-
Gillece P, Luz JM, Lennarz WJ, de La Cruz FJ, Römisch K. 1999. Export of a cysteine-free misfolded secretory protein from the endoplasmic reticulum for degradation requires interaction with protein disulfide isomerase. J. Cell. Biol. 147:1443-56
-
(1999)
J. Cell. Biol.
, vol.147
, pp. 1443-1456
-
-
Gillece, P.1
Luz, J.M.2
Lennarz, W.J.3
De La Cruz, F.J.4
Römisch, K.5
-
25
-
-
4344560565
-
Cystic fibrosis transmembrane conductance regulator degradation depends on the lectins Htm1p/EDEM and the Cdc48 protein complex in yeast
-
Gnann A, Riordan JR, Wolf DH. 2004. Cystic fibrosis transmembrane conductance regulator degradation depends on the lectins Htm1p/EDEM and the Cdc48 protein complex in yeast. Mol. Biol. Cell. 15:4125-35
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 4125-4135
-
-
Gnann, A.1
Riordan, J.R.2
Wolf, D.H.3
-
26
-
-
0346727127
-
Protein degradation and protection against misfolded or damaged proteins
-
Goldberg AL. 2003. Protein degradation and protection against misfolded or damaged proteins. Nature 426:895-99
-
(2003)
Nature
, vol.426
, pp. 895-899
-
-
Goldberg, A.L.1
-
27
-
-
0036702298
-
ER-associated degradation in protein quality control and cellular regulation
-
Hampton RY. 2002. ER-associated degradation in protein quality control and cellular regulation. Curr. Opin. Cell. Biol. 14:476-82
-
(2002)
Curr. Opin. Cell. Biol.
, vol.14
, pp. 476-482
-
-
Hampton, R.Y.1
-
28
-
-
0035163285
-
O-mannosylation protects mutant alpha-factor precursor from endoplasmic reticulum-associated degradation
-
Harty C, Strahl S, Römisch K. 2001. O-mannosylation protects mutant alpha-factor precursor from endoplasmic reticulum-associated degradation. Mol. Biol. Cell. 12:1093-101
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1093-1101
-
-
Harty, C.1
Strahl, S.2
Römisch, K.3
-
29
-
-
3943059566
-
Roles of N-linked glycans in the endoplasmic reticulum
-
Helenius A, Aebi M. 2004. Roles of N-linked glycans in the endoplasmic reticulum. Annu. Rev. Biochem. 73:1019-49
-
(2004)
Annu. Rev. Biochem.
, vol.73
, pp. 1019-1049
-
-
Helenius, A.1
Aebi, M.2
-
30
-
-
0034838656
-
Structure and function of Class I alpha 1,2-mannosidases involved in glycoprotein synthesis and endoplasmic reticulum quality control
-
Herscovics A. 2001. Structure and function of Class I alpha 1,2-mannosidases involved in glycoprotein synthesis and endoplasmic reticulum quality control. Biochimie 83:757-62
-
(2001)
Biochimie
, vol.83
, pp. 757-762
-
-
Herscovics, A.1
-
31
-
-
0037416196
-
A role for N-glycanase in the cytosolic turnover of glycoproteins
-
Hirsch C, Blom D, Ploegh HL. 2003. A role for N-glycanase in the cytosolic turnover of glycoproteins. EMBO J. 22:1036-46
-
(2003)
EMBO J.
, vol.22
, pp. 1036-1046
-
-
Hirsch, C.1
Blom, D.2
Ploegh, H.L.3
-
32
-
-
1442331636
-
Yeast N-glycanase distinguishes between native and non-native glycoproteins
-
Hirsch C, Misaghi S, Blom D, Pacold ME, Ploegh HL. 2004. Yeast N-glycanase distinguishes between native and non-native glycoproteins. EMBO Rep. 5:201-6
-
(2004)
EMBO Rep.
, vol.5
, pp. 201-206
-
-
Hirsch, C.1
Misaghi, S.2
Blom, D.3
Pacold, M.E.4
Ploegh, H.L.5
-
33
-
-
0742270608
-
A striking quality control subcompartment in Saccharomyces cerevisiae: The endoplasmic reticulum-associated compartment
-
Huyer G, Longsworth GL, Mason DL, Mallampalli MP, McCaffery JM, et al. 2004a. A striking quality control subcompartment in Saccharomyces cerevisiae: the endoplasmic reticulum-associated compartment. Mol. Biol. Cell. 15:908-21
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 908-921
-
-
Huyer, G.1
Longsworth, G.L.2
Mason, D.L.3
Mallampalli, M.P.4
McCaffery, J.M.5
-
34
-
-
4444355303
-
Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein
-
Huyer G, Piluek WF, Fansler Z, Kreft SG, Hochstrasser M, et al. 2004b. Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein. J. Biol. Chem. 279:38369-78
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 38369-38378
-
-
Huyer, G.1
Piluek, W.F.2
Fansler, Z.3
Kreft, S.G.4
Hochstrasser, M.5
-
35
-
-
12444339508
-
Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells
-
Imai J, Hasegawa H, Maruya M, Koyasu S, Yahara I. 2005. Exogenous antigens are processed through the endoplasmic reticulum-associated degradation (ERAD) in cross-presentation by dendritic cells. Int. Immunol. 17:45-53
-
(2005)
Int. Immunol.
, vol.17
, pp. 45-53
-
-
Imai, J.1
Hasegawa, H.2
Maruya, M.3
Koyasu, S.4
Yahara, I.5
-
36
-
-
0034980520
-
Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast
-
Jakob CA, Bodmer D, Spirig U, Battig P, Marcil A, et al. 2001. Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast. EMBO Rep. 2:423-30
-
(2001)
EMBO Rep.
, vol.2
, pp. 423-430
-
-
Jakob, C.A.1
Bodmer, D.2
Spirig, U.3
Battig, P.4
Marcil, A.5
-
37
-
-
0036173013
-
Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48
-
Jarosch E, Taxis C, Volkwein C, Bordallo J, Finley D, et al. 2002. Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48. Nat. Cell. Biol. 4:134-39
-
(2002)
Nat. Cell. Biol.
, vol.4
, pp. 134-139
-
-
Jarosch, E.1
Taxis, C.2
Volkwein, C.3
Bordallo, J.4
Finley, D.5
-
38
-
-
0028858161
-
Multiple proteolytic systems, including the proteasome, contribute to CFTR processing
-
Jensen TJ, Loo MA, Pind S, Williams DB, Goldberg AL, Riordan JR. 1995. Multiple proteolytic systems, including the proteasome, contribute to CFTR processing. Cell 83:129-35
-
(1995)
Cell
, vol.83
, pp. 129-135
-
-
Jensen, T.J.1
Loo, M.A.2
Pind, S.3
Williams, D.B.4
Goldberg, A.L.5
Riordan, J.R.6
-
40
-
-
0042970598
-
Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP
-
Kabani M, Kelley SS, Morrow MW, Montgomery DL, Sivendran R, et al. 2003. Dependence of endoplasmic reticulum-associated degradation on the peptide binding domain and concentration of BiP. Mol. Biol. Cell. 14:3437-48
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 3437-3448
-
-
Kabani, M.1
Kelley, S.S.2
Morrow, M.W.3
Montgomery, D.L.4
Sivendran, R.5
-
41
-
-
22744456680
-
The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane
-
Kalies KU, Allan S, Sergeyenko T, Kroger H, Romish K. 2005. The protein translocation channel binds proteasomes to the endoplasmic reticulum membrane. EMBO J. 24:2284-93
-
(2005)
EMBO J.
, vol.24
, pp. 2284-2293
-
-
Kalies, K.U.1
Allan, S.2
Sergeyenko, T.3
Kroger, H.4
Romish, K.5
-
42
-
-
4644318292
-
A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins
-
Katiyar S, Li G, Lennarz WJ. 2004. A complex between peptide:N-glycanase and two proteasome-linked proteins suggests a mechanism for the degradation of misfolded glycoproteins. Proc. Natl. Acad. Sci. USA 101:13774-79
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 13774-13779
-
-
Katiyar, S.1
Li, G.2
Lennarz, W.J.3
-
43
-
-
3042764201
-
Multiple interactions of rad23 suggest a mechanism for ubiquitylated substrate delivery important in proteolysis
-
Kim I, Mi K, Rao H. 2004. Multiple interactions of rad23 suggest a mechanism for ubiquitylated substrate delivery important in proteolysis. Mol. Biol. Cell. 15:3357-65
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 3357-3365
-
-
Kim, I.1
Mi, K.2
Rao, H.3
-
44
-
-
27244462469
-
Expression and degradation of the cystic fibrosis transmembrane conductance regulator in Saccharomyces cerevisiae
-
Kiser GL, Gentzsch M, Kloser AK, Balzi E, Wolf DH, et al. 2001. Expression and degradation of the cystic fibrosis transmembrane conductance regulator in Saccharomyces cerevisiae. Arch. Biochem. Biophys. 390:195-205
-
(2001)
Arch. Biochem. Biophys.
, vol.390
, pp. 195-205
-
-
Kiser, G.L.1
Gentzsch, M.2
Kloser, A.K.3
Balzi, E.4
Wolf, D.H.5
-
45
-
-
0025041029
-
Protein degradation in the endoplasmic reticulum
-
Klausner RD, Sitia R. 1990. Protein degradation in the endoplasmic reticulum. Cell 62:611-14
-
(1990)
Cell
, vol.62
, pp. 611-614
-
-
Klausner, R.D.1
Sitia, R.2
-
46
-
-
0030041781
-
Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast
-
Knop M, Finger A, Braun T, Hellmuth K, Wolf DH. 1996. Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast. EMBO J. 15:753-63
-
(1996)
EMBO J.
, vol.15
, pp. 753-763
-
-
Knop, M.1
Finger, A.2
Braun, T.3
Hellmuth, K.4
Wolf, D.H.5
-
47
-
-
0033525589
-
A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly
-
Koegl M, Hoppe T, Schlenker S, Ulrich HD, Mayer TU, Jentsch S. 1999. A novel ubiquitination factor, E4, is involved in multiubiquitin chain assembly. Cell 96:635-44
-
(1999)
Cell
, vol.96
, pp. 635-644
-
-
Koegl, M.1
Hoppe, T.2
Schlenker, S.3
Ulrich, H.D.4
Mayer, T.U.5
Jentsch, S.6
-
48
-
-
0037129213
-
A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal
-
Lam YA, Lawson TG, Velayutham M, Zweier JL, Pickart CM. 2002. A proteasomal ATPase subunit recognizes the polyubiquitin degradation signal. Nature 416:763-67
-
(2002)
Nature
, vol.416
, pp. 763-767
-
-
Lam, Y.A.1
Lawson, T.G.2
Velayutham, M.3
Zweier, J.L.4
Pickart, C.M.5
-
49
-
-
0034194179
-
AAA proteases: Cellular machines for degrading membrane proteins
-
Langer T. 2000. AAA proteases: cellular machines for degrading membrane proteins. Trends Biochem. Sci. 25:247-51
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 247-251
-
-
Langer, T.1
-
50
-
-
3042543543
-
The 19S cap of the 26S proteasome is sufficient to retro-translocate and deliver a soluble polypeptide for ER-associated degradation
-
Lee RJ, Liu C, Harty C, McCracken AA, Romisch K, et al. 2004. The 19S cap of the 26S proteasome is sufficient to retro-translocate and deliver a soluble polypeptide for ER-associated degradation. EMBO J. 23:2206-15
-
(2004)
EMBO J.
, vol.23
, pp. 2206-2215
-
-
Lee, R.J.1
Liu, C.2
Harty, C.3
McCracken, A.A.4
Romisch, K.5
-
51
-
-
3042616595
-
A membrane protein required for dislocation of misfolded proteins from the ER
-
Lilley BN, Ploegh HL. 2004. A membrane protein required for dislocation of misfolded proteins from the ER. Nature 429:834-40
-
(2004)
Nature
, vol.429
, pp. 834-840
-
-
Lilley, B.N.1
Ploegh, H.L.2
-
52
-
-
2942638034
-
Alpha1-antitrypsin deficiency: Molecular pathophysiology
-
Lomas DA, Parfrey H. 2004. Alpha1-antitrypsin deficiency: molecular pathophysiology. Thorax 59:529-35
-
(2004)
Thorax
, vol.59
, pp. 529-535
-
-
Lomas, D.A.1
Parfrey, H.2
-
53
-
-
0032401771
-
Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome
-
Loo MA, Jensen TJ, Cui L, Hou Y, Chang XB, Riordan JR. 1998. Perturbation of Hsp90 interaction with nascent CFTR prevents its maturation and accelerates its degradation by the proteasome. EMBO J. 17:6879-87
-
(1998)
EMBO J.
, vol.17
, pp. 6879-6887
-
-
Loo, M.A.1
Jensen, T.J.2
Cui, L.3
Hou, Y.4
Chang, X.B.5
Riordan, J.R.6
-
54
-
-
0030070704
-
Assembly of ER-associated protein degradation in vitro: Dependence on cytosol, calnexin, and ATP
-
McCracken AA, Brodsky JL. 1996. Assembly of ER-associated protein degradation in vitro: dependence on cytosol, calnexin, and ATP. J. Cell. Biol. 132:291-98
-
(1996)
J. Cell. Biol.
, vol.132
, pp. 291-298
-
-
McCracken, A.A.1
Brodsky, J.L.2
-
55
-
-
4444320698
-
A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation
-
Medicherla B, Kostova Z, Schaefer A, WolfDH. 2004. A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation. EMBO Rep. 5:692-97
-
(2004)
EMBO Rep.
, vol.5
, pp. 692-697
-
-
Medicherla, B.1
Kostova, Z.2
Schaefer, A.3
Wolf, D.H.4
-
56
-
-
0036911213
-
A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins
-
Meunier L, Usherwood YK, Chung KT, Hendershot LM. 2002. A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. Mol. Biol. Cell. 13:4456-69
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 4456-4469
-
-
Meunier, L.1
Usherwood, Y.K.2
Chung, K.T.3
Hendershot, L.M.4
-
57
-
-
1942534656
-
Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation
-
Meusser B, Sommer T. 2004. Vpu-mediated degradation of CD4 reconstituted in yeast reveals mechanistic differences to cellular ER-associated protein degradation. Mol. Cell 14:247-58
-
(2004)
Mol. Cell
, vol.14
, pp. 247-258
-
-
Meusser, B.1
Sommer, T.2
-
58
-
-
0034640293
-
Mammalian Sec61 is associated with Sec62 and Sec63
-
Meyer HA, Grau H, Kraft R, Kostka S, Prehn S, et al. 2000a. Mammalian Sec61 is associated with Sec62 and Sec63. J. Biol. Chem. 275:14550-57
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 14550-14557
-
-
Meyer, H.A.1
Grau, H.2
Kraft, R.3
Kostka, S.4
Prehn, S.5
-
59
-
-
0034658270
-
A complex of mammalian ufd1 and np14 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways
-
Meyer HH, Shorter JG, Seemann J, Pappin D, Warren G. 2000b. A complex of mammalian ufd1 and np14 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways. EMBO J. 19:2181-92
-
(2000)
EMBO J.
, vol.19
, pp. 2181-2192
-
-
Meyer, H.H.1
Shorter, J.G.2
Seemann, J.3
Pappin, D.4
Warren, G.5
-
60
-
-
3142582012
-
Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum
-
Miranda E, Römisch K, Lomas DA. 2004. Mutants of neuroserpin that cause dementia accumulate as polymers within the endoplasmic reticulum. J. Biol. Chem. 279:28283-91
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 28283-28291
-
-
Miranda, E.1
Römisch, K.2
Lomas, D.A.3
-
61
-
-
10644226176
-
Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover
-
Misaghi S, Pacold ME, Blom D, Ploegh HL, Korbel GA. 2004. Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover. Chem. Biol. 11:1677-87
-
(2004)
Chem. Biol.
, vol.11
, pp. 1677-1687
-
-
Misaghi, S.1
Pacold, M.E.2
Blom, D.3
Ploegh, H.L.4
Korbel, G.A.5
-
62
-
-
0037470410
-
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle
-
Molinari M, Calanca V, Galli C, Lucca P, Paganetti P. 2003. Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle. Science 299:1397-400
-
(2003)
Science
, vol.299
, pp. 1397-1400
-
-
Molinari, M.1
Calanca, V.2
Galli, C.3
Lucca, P.4
Paganetti, P.5
-
63
-
-
0037157856
-
Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER
-
Molinari M, Galli C, Piccaluga V, Pieren M, Paganetti P. 2002. Sequential assistance of molecular chaperones and transient formation of covalent complexes during protein degradation from the ER. J. Cell. Biol. 158:247-57
-
(2002)
J. Cell. Biol.
, vol.158
, pp. 247-257
-
-
Molinari, M.1
Galli, C.2
Piccaluga, V.3
Pieren, M.4
Paganetti, P.5
-
64
-
-
9644294223
-
Roles of O-mannosylation of aberrant proteins in reduction of the load for endoplasmic reticulum chaperones in yeast
-
Nakatsukasa K, Okada S, Umebayashi K, Fukuda R, Nishikawa S, Endo T. 2004. Roles of O-mannosylation of aberrant proteins in reduction of the load for endoplasmic reticulum chaperones in yeast. J. Biol. Chem. 279:49762-72
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49762-49772
-
-
Nakatsukasa, K.1
Okada, S.2
Umebayashi, K.3
Fukuda, R.4
Nishikawa, S.5
Endo, T.6
-
65
-
-
0034632033
-
The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control
-
Ng DT, Spear ED, Walter P. 2000. The unfolded protein response regulates multiple aspects of secretory and membrane protein biogenesis and endoplasmic reticulum quality control. J. Cell. Biol. 150:77-88
-
(2000)
J. Cell. Biol.
, vol.150
, pp. 77-88
-
-
Ng, D.T.1
Spear, E.D.2
Walter, P.3
-
66
-
-
0035947773
-
Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation
-
Nishikawa S, Fewell SW, Kato Y, Brodsky JL, Endo T. 2001. Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation. J. Cell Biol. 153:1061-70
-
(2001)
J. Cell Biol.
, vol.153
, pp. 1061-1070
-
-
Nishikawa, S.1
Fewell, S.W.2
Kato, Y.3
Brodsky, J.L.4
Endo, T.5
-
67
-
-
0028073895
-
Inhibition of endoplasmic reticulum (ER)-to-Golgi transport induces relocalization of binding protein (BiP) within the ER to form the BiP bodies
-
Nishikawa S, Hirata A, Nakano A. 1994. Inhibition of endoplasmic reticulum (ER)-to-Golgi transport induces relocalization of binding protein (BiP) within the ER to form the BiP bodies. Mol. Biol. Cell. 5:1129-43
-
(1994)
Mol. Biol. Cell
, vol.5
, pp. 1129-1143
-
-
Nishikawa, S.1
Hirata, A.2
Nakano, A.3
-
68
-
-
0031770876
-
Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane
-
Pilon M, Römisch K, Quach D, Schekman R. 1998. Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane. Mol. Biol. Cell. 9:3455-73
-
(1998)
Mol. Biol. Cell
, vol.9
, pp. 3455-3473
-
-
Pilon, M.1
Römisch, K.2
Quach, D.3
Schekman, R.4
-
69
-
-
0030789680
-
Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation
-
Pilon M, Schekman R, Römisch K. 1997. Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation. EMBO J. 16:4540-48
-
(1997)
EMBO J.
, vol.16
, pp. 4540-4548
-
-
Pilon, M.1
Schekman, R.2
Römisch, K.3
-
70
-
-
1842409617
-
Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation
-
Plemper RK, Bohmler S, Bordallo J, Sommer T, Wolf DH. 1997. Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation. Nature 388:891-95
-
(1997)
Nature
, vol.388
, pp. 891-895
-
-
Plemper, R.K.1
Bohmler, S.2
Bordallo, J.3
Sommer, T.4
Wolf, D.H.5
-
71
-
-
0032484024
-
Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome
-
Plemper RK, Egner R, Kuchler K, Wolf DH. 1998. Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome. J. Biol. Chem. 273:32848-56
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32848-32856
-
-
Plemper, R.K.1
Egner, R.2
Kuchler, K.3
Wolf, D.H.4
-
72
-
-
0034618102
-
Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae
-
Prinz WA, Grzyb L, Veenhuis M, Kahana JA, Silver PA, Rapoport TA. 2000. Mutants affecting the structure of the cortical endoplasmic reticulum in Saccharomyces cerevisiae. J. Cell. Biol. 150:461-74
-
(2000)
J. Cell. Biol.
, vol.150
, pp. 461-474
-
-
Prinz, W.A.1
Grzyb, L.2
Veenhuis, M.3
Kahana, J.A.4
Silver, P.A.5
Rapoport, T.A.6
-
73
-
-
0035977095
-
Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48 (UFD1/NPL4), a ubiquitin-selective chaperone
-
Rape M, Hoppe T, Gorr I, Kalocay M, Richly H, Jentsch S. 2001. Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48 (UFD1/NPL4), a ubiquitin-selective chaperone. Cell 107:667-77
-
(2001)
Cell
, vol.107
, pp. 667-677
-
-
Rape, M.1
Hoppe, T.2
Gorr, I.3
Kalocay, M.4
Richly, H.5
Jentsch, S.6
-
74
-
-
11844263929
-
A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting
-
Richly J, Rape M, Braun S, Rumpf S, Hoege C, Jentsch S. 2005. A series of ubiquitin binding factors connects CDC48/p97 to substrate multiubiquitylation and proteasomal targeting. Cell 120:73-84
-
(2005)
Cell
, vol.120
, pp. 73-84
-
-
Richly, J.1
Rape, M.2
Braun, S.3
Rumpf, S.4
Hoege, C.5
Jentsch, S.6
-
75
-
-
0032006110
-
Intracellular distribution of proteasomes
-
Rivett AJ. 1998. Intracellular distribution of proteasomes. Curr. Opin. Immunol. 10:110-14
-
(1998)
Curr. Opin. Immunol.
, vol.10
, pp. 110-114
-
-
Rivett, A.J.1
-
76
-
-
7244245559
-
A cure for traffic jams: Small molecule chaperones in the endoplasmic reticulum
-
Römisch K. 2004. A cure for traffic jams: small molecule chaperones in the endoplasmic reticulum. Traffic 5:815-20
-
(2004)
Traffic
, vol.5
, pp. 815-820
-
-
Römisch, K.1
-
77
-
-
0030917149
-
Similar processes mediate glycopeptide export from the endoplasmic reticulum in mammalian cells and Saccharomyces cerevisiae
-
Römisch K, Ali BRS. 1997. Similar processes mediate glycopeptide export from the endoplasmic reticulum in mammalian cells and Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 94:6730-34
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6730-6734
-
-
Römisch, K.1
Ali, B.R.S.2
-
78
-
-
0032168508
-
Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome
-
Rubin DM, Glickman MH, Larsen CN, Dhruvakamar S, Finley D. 1998. Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J. 17:4909-19
-
(1998)
EMBO J.
, vol.17
, pp. 4909-4919
-
-
Rubin, D.M.1
Glickman, M.H.2
Larsen, C.N.3
Dhruvakamar, S.4
Finley, D.5
-
79
-
-
0034689054
-
Cholera toxin is exported from microsomes by the Sec61p complex
-
Schmitz A, Herrgen H, Winkeler A, Herzog V. 2000. Cholera toxin is exported from microsomes by the Sec61p complex. J. Cell. Biol. 148:1203-12
-
(2000)
J. Cell. Biol.
, vol.148
, pp. 1203-1212
-
-
Schmitz, A.1
Herrgen, H.2
Winkeler, A.3
Herzog, V.4
-
80
-
-
1042292018
-
Endoplasmic reticulum-localized amyloid beta-peptide is degraded in the cytosol by two distinct degradation pathways
-
Schmitz A, Schneider A, Kummer MP, Herzog V. 2004. Endoplasmic reticulum-localized amyloid beta-peptide is degraded in the cytosol by two distinct degradation pathways. Traffic 5:89-101
-
(2004)
Traffic
, vol.5
, pp. 89-101
-
-
Schmitz, A.1
Schneider, A.2
Kummer, M.P.3
Herzog, V.4
-
81
-
-
0034643336
-
Rapid degradation of a large fraction of newly synthesized proteins by proteasomes
-
Schubert U, Anton LC, Gibbs J, Norbury CC, Yewdell JW, Bennink JR. 2000. Rapid degradation of a large fraction of newly synthesized proteins by proteasomes. Nature 404:770-74
-
(2000)
Nature
, vol.404
, pp. 770-774
-
-
Schubert, U.1
Anton, L.C.2
Gibbs, J.3
Norbury, C.C.4
Yewdell, J.W.5
Bennink, J.R.6
-
82
-
-
4043111286
-
Endoplasmic reticulum-associated degradation-induced dissociation of class II invariant chain complexes containing a glycosylation-deficient form of p41
-
Sevilla LM, Comstock SS, Swier K, Miller J. 2004. Endoplasmic reticulum-associated degradation-induced dissociation of class II invariant chain complexes containing a glycosylation-deficient form of p41. J. Immunol. 173:2586-93
-
(2004)
J. Immunol.
, vol.173
, pp. 2586-2593
-
-
Sevilla, L.M.1
Comstock, S.S.2
Swier, K.3
Miller, J.4
-
83
-
-
0035167960
-
Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol
-
Shamu CE, Flierman D, Ploegh HL, Rapoport TA, Chau V. 2001. Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol. Mol. Biol. Cell. 12:2546-55
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2546-2555
-
-
Shamu, C.E.1
Flierman, D.2
Ploegh, H.L.3
Rapoport, T.A.4
Chau, V.5
-
84
-
-
0033523771
-
The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate
-
Shamu CE, Story CM, Rapoport TA, Ploegh HL. 1999. The pathway of US11-dependent degradation of MHC class I heavy chains involves a ubiquitin-conjugated intermediate. J. Cell. Biol. 147:45-58
-
(1999)
J. Cell. Biol.
, vol.147
, pp. 45-58
-
-
Shamu, C.E.1
Story, C.M.2
Rapoport, T.A.3
Ploegh, H.L.4
-
85
-
-
0034729193
-
PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase
-
Suzuki T, Park H, Hollingsworth NM, Sternglanz R, Lennarz WJ. 2000. PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase. J. Cell. Biol. 149:1039-52
-
(2000)
J. Cell. Biol.
, vol.149
, pp. 1039-1052
-
-
Suzuki, T.1
Park, H.2
Hollingsworth, N.M.3
Sternglanz, R.4
Lennarz, W.J.5
-
86
-
-
0028362217
-
Purification and enzymatic properties of peptide: N-glycanase from C3H mouse-derived L-929 fibroblast cells. Possible widespread occurrence of post-translational remodification of proteins by N-deglycosylation
-
Suzuki T, Seko A, Kitajima K, Inoue Y, Inoue S. 1994. Purification and enzymatic properties of peptide: N-glycanase from C3H mouse-derived L-929 fibroblast cells. Possible widespread occurrence of post-translational remodification of proteins by N-deglycosylation. J. Biol. Chem. 269:17611-18
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 17611-17618
-
-
Suzuki, T.1
Seko, A.2
Kitajima, K.3
Inoue, Y.4
Inoue, S.5
-
87
-
-
0141592584
-
Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD
-
Taxis C, Hitt R, Park SH, Deak PM, Kostova Z, Wolf DH. 2003. Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD. J. Biol. Chem. 278:35903-13
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 35903-35913
-
-
Taxis, C.1
Hitt, R.2
Park, S.H.3
Deak, P.M.4
Kostova, Z.5
Wolf, D.H.6
-
88
-
-
0035985150
-
ER-Golgi traffic is a prerequisite for efficient ER degradation
-
Taxis C, Vogel F, Wolf DH. 2002. ER-Golgi traffic is a prerequisite for efficient ER degradation. Mol. Biol. Cell. 13:1806-18
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 1806-1818
-
-
Taxis, C.1
Vogel, F.2
Wolf, D.H.3
-
89
-
-
0033570916
-
An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator
-
Tector M, Hartl FU. 1999. An unstable transmembrane segment in the cystic fibrosis transmembrane conductance regulator. EMBO J. 18:6290-98
-
(1999)
EMBO J.
, vol.18
, pp. 6290-6298
-
-
Tector, M.1
Hartl, F.U.2
-
90
-
-
0037470054
-
Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation
-
Tirosh B, Furman MH, Tortorella D, Ploegh HL. 2003. Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation. J. Biol. Chem. 278:6664-72
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 6664-6672
-
-
Tirosh, B.1
Furman, M.H.2
Tortorella, D.3
Ploegh, H.L.4
-
91
-
-
0032572582
-
Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential
-
Tortorella D, Story CM, Huppa JB, Wiertz EJ, Jones TR, et al. 1998. Dislocation of type I membrane proteins from the ER to the cytosol is sensitive to changes in redox potential. J. Cell. Biol. 142:365-76.
-
(1998)
J. Cell. Biol.
, vol.142
, pp. 365-376
-
-
Tortorella, D.1
Story, C.M.2
Huppa, J.B.3
Wiertz, E.J.4
Jones, T.R.5
-
92
-
-
28444491652
-
-
Erratum. 1999. J. Cell. Biol. 145(3):642
-
(1999)
J. Cell. Biol.
, vol.145
, Issue.3
, pp. 642
-
-
-
93
-
-
0344393021
-
Quality control and protein folding in the secretory pathway
-
Trombetta ES, Parodi AJ. 2003. Quality control and protein folding in the secretory pathway. Annu. Rev. Cell. Dev. Biol. 19:649-76
-
(2003)
Annu. Rev. Cell. Dev. Biol.
, vol.19
, pp. 649-676
-
-
Trombetta, E.S.1
Parodi, A.J.2
-
94
-
-
0035937408
-
Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin
-
Tsai B, Rodighiero C, Lencer WI, Rapoport TA. 2001. Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin. Cell 104:937-48
-
(2001)
Cell
, vol.104
, pp. 937-948
-
-
Tsai, B.1
Rodighiero, C.2
Lencer, W.I.3
Rapoport, T.A.4
-
95
-
-
12944254591
-
Homologs of the yeast Sec complex subunits Sec62p and Sec63p are abundant proteins in dog pancreas microsomes
-
Tyedmers J, Lerner M, Bies C, Dudek J, Skowronek MH, et al. 2000. Homologs of the yeast Sec complex subunits Sec62p and Sec63p are abundant proteins in dog pancreas microsomes. Proc. Natl. Acad. Sci. USA 97:7214-19
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7214-7219
-
-
Tyedmers, J.1
Lerner, M.2
Bies, C.3
Dudek, J.4
Skowronek, M.H.5
-
96
-
-
1842832344
-
Two distinctly localized p-type ATPases collaborate to maintain organelle homeostasis required for glycoprotein processing and quality control
-
Vashist S, Frank CG, Jakob CA, Ng DT. 2002. Two distinctly localized p-type ATPases collaborate to maintain organelle homeostasis required for glycoprotein processing and quality control. Mol. Biol. Cell. 13:3955-66
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3955-3966
-
-
Vashist, S.1
Frank, C.G.2
Jakob, C.A.3
Ng, D.T.4
-
97
-
-
0035851911
-
Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding
-
Vashist S, Kim W, Belden WJ, Spear ED, Barlowe C, Ng DT. 2001. Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein folding. J. Cell. Biol. 155:355-68
-
(2001)
J. Cell. Biol.
, vol.155
, pp. 355-368
-
-
Vashist, S.1
Kim, W.2
Belden, W.J.3
Spear, E.D.4
Barlowe, C.5
Ng, D.T.6
-
98
-
-
2442451126
-
Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control
-
Vashist S, Ng DT. 2004. Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control. J. Cell. Biol. 165:41-52
-
(2004)
J. Cell. Biol.
, vol.165
, pp. 41-52
-
-
Vashist, S.1
Ng, D.T.2
-
99
-
-
3142566639
-
Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin proteasome system
-
Verma R, Oania R, Graumann J, Deshaies RJ. 2004. Multiubiquitin chain receptors define a layer of substrate selectivity in the ubiquitin proteasome system. Cell 118:99-110
-
(2004)
Cell
, vol.118
, pp. 99-110
-
-
Verma, R.1
Oania, R.2
Graumann, J.3
Deshaies, R.J.4
-
100
-
-
0035875921
-
Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p
-
Walter J, Urban J, Volkwein C, Sommer T. 2001. Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p. EMBO J. 20:3124-31
-
(2001)
EMBO J.
, vol.20
, pp. 3124-3131
-
-
Walter, J.1
Urban, J.2
Volkwein, C.3
Sommer, T.4
-
101
-
-
0043026909
-
Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family
-
Wang Q, Chang A. 2003. Substrate recognition in ER-associated degradation mediated by Eps1, a member of the protein disulfide isomerase family. EMBO J. 22:3792-802
-
(2003)
EMBO J.
, vol.22
, pp. 3792-3802
-
-
Wang, Q.1
Chang, A.2
-
102
-
-
0028840915
-
Degradation of CFTR by the ubiquitin-proteasome pathway
-
Ward CL, Omura S, Kopito RR. 1995. Degradation of CFTR by the ubiquitin-proteasome pathway. Cell 83:121-27
-
(1995)
Cell
, vol.83
, pp. 121-127
-
-
Ward, C.L.1
Omura, S.2
Kopito, R.R.3
-
103
-
-
0030447659
-
Proteasome-dependent endoplasmic reticulum-associated protein degradation: An unconventional route to a familiar fate
-
Werner ED, Brodsky JL, McCracken AA. 1996. Proteasome-dependent endoplasmic reticulum-associated protein degradation: an unconventional route to a familiar fate. Proc. Natl. Acad. Sci. USA 93:13797-801
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 13797-13801
-
-
Werner, E.D.1
Brodsky, J.L.2
McCracken, A.A.3
-
104
-
-
0029915568
-
The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol
-
Wiertz EJ, Jones TR, Sun L, Bogyo M, Geuze HJ, Ploegh HL. 1996a. The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell 84:769-79
-
(1996)
Cell
, vol.84
, pp. 769-779
-
-
Wiertz, E.J.1
Jones, T.R.2
Sun, L.3
Bogyo, M.4
Geuze, H.J.5
Ploegh, H.L.6
-
105
-
-
0029828991
-
Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction
-
Wiertz EJ, Tortorella D, Bogyo M, Yu J, Mothes W, et al. 1996b. Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature 384:432-38
-
(1996)
Nature
, vol.384
, pp. 432-438
-
-
Wiertz, E.J.1
Tortorella, D.2
Bogyo, M.3
Yu, J.4
Mothes, W.5
-
106
-
-
0034614525
-
Distinct domains within yeast Sec61p involved in post-translational translocation and protein dislocation
-
Wilkinson BM, Tyson JR, Reid PJ, Stirling CJ. 2000. Distinct domains within yeast Sec61p involved in post-translational translocation and protein dislocation. J. Biol. Chem. 275:521-29
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 521-529
-
-
Wilkinson, B.M.1
Tyson, J.R.2
Reid, P.J.3
Stirling, C.J.4
-
107
-
-
0035463587
-
Ssh1p determines the translocation and dislocation capacities of the yeast endoplasmic reticulum
-
Wilkinson BM, Tyson JR, Stirling CJ. 2001. Ssh1p determines the translocation and dislocation capacities of the yeast endoplasmic reticulum. Dev. Cell 1:401-9
-
(2001)
Dev. Cell
, vol.1
, pp. 401-409
-
-
Wilkinson, B.M.1
Tyson, J.R.2
Stirling, C.J.3
-
108
-
-
0242635839
-
P97, a protein coping with multiple identities
-
Woodman PG. 2003. p97, a protein coping with multiple identities. J. Cell. Sci. 116:4283-90
-
(2003)
J. Cell. Sci.
, vol.116
, pp. 4283-4290
-
-
Woodman, P.G.1
-
109
-
-
0023788653
-
Increased amounts of HMG-CoA reductase induce "karmellae": A proliferation of stacked membrane pairs surrounding the yeast nucleus
-
Wright R, Basson M, D'Ari L, Rine J. 1988. Increased amounts of HMG-CoA reductase induce "karmellae": a proliferation of stacked membrane pairs surrounding the yeast nucleus. J. Cell. Biol. 107:101-14
-
(1988)
J. Cell. Biol.
, vol.107
, pp. 101-114
-
-
Wright, R.1
Basson, M.2
D'Ari, L.3
Rine, J.4
-
110
-
-
0037816258
-
Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation
-
Wu Y, Swulius MT, Moremen KW, Sifers RN. 2003. Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation. Proc. Natl. Acad. Sci. USA 100:8229-34
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 8229-8234
-
-
Wu, Y.1
Swulius, M.T.2
Moremen, K.W.3
Sifers, R.N.4
-
111
-
-
0035818999
-
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER to the cytosol
-
Ye Y, Meyer HH, Rapoport TA. 2001. The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER to the cytosol. Nature 414:652-56
-
(2001)
Nature
, vol.414
, pp. 652-656
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
112
-
-
0038487228
-
Function of the p97-Ufd1-Np14 complex in retrotranslocation from the ER to the cytosol: Dual recognition of non-ubiquitinated polypeptide segments and polyubiquitin chains
-
Ye Y, Meyer HH, Rapoport TA. 2003. Function of the p97-Ufd1-Np14 complex in retrotranslocation from the ER to the cytosol: dual recognition of non-ubiquitinated polypeptide segments and polyubiquitin chains. J. Cell. Biol. 162:71-84
-
(2003)
J. Cell. Biol.
, vol.162
, pp. 71-84
-
-
Ye, Y.1
Meyer, H.H.2
Rapoport, T.A.3
-
113
-
-
3042677637
-
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
-
Ye Y, Shibata Y, Yun C, Ron D, Rapoport TA. 2004. A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol. Nature 429:841-47
-
(2004)
Nature
, vol.429
, pp. 841-847
-
-
Ye, Y.1
Shibata, Y.2
Yun, C.3
Ron, D.4
Rapoport, T.A.5
-
114
-
-
18444413218
-
E3 ubiquitin ligase that recognizes sugar chains
-
Yoshida Y, Chiba T, Tokunaga F, Kawasaki H, Iwai K, et al. 2002. E3 ubiquitin ligase that recognizes sugar chains. Nature 418:438-42
-
(2002)
Nature
, vol.418
, pp. 438-442
-
-
Yoshida, Y.1
Chiba, T.2
Tokunaga, F.3
Kawasaki, H.4
Iwai, K.5
-
115
-
-
0242321836
-
Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains
-
Yoshida Y, Tokunaga F, Chiba T, Iwai K, Tanaka K, Tai T. 2003. Fbs2 is a new member of the E3 ubiquitin ligase family that recognizes sugar chains. J. Biol. Chem. 278:43877-84
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 43877-43884
-
-
Yoshida, Y.1
Tokunaga, F.2
Chiba, T.3
Iwai, K.4
Tanaka, K.5
Tai, T.6
-
116
-
-
6344275303
-
Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast
-
Youker RT, Walsh P, Beilharz T, Lithgow T, Brodsky JL. 2004. Distinct roles for the Hsp40 and Hsp90 molecular chaperones during cystic fibrosis transmembrane conductance regulator degradation in yeast. Mol. Biol. Cell. 15:4787-97
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 4787-4797
-
-
Youker, R.T.1
Walsh, P.2
Beilharz, T.3
Lithgow, T.4
Brodsky, J.L.5
-
117
-
-
0034757165
-
Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast
-
Zhang Y, Nijbroek G, Sullivan ML, McCracken AA, Watkins SC, et al. 2001. Hsp70 molecular chaperone facilitates endoplasmic reticulum-associated protein degradation of cystic fibrosis transmembrane conductance regulator in yeast. Mol. Biol. Cell. 12:1303-14
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 1303-1314
-
-
Zhang, Y.1
Nijbroek, G.2
Sullivan, M.L.3
McCracken, A.A.4
Watkins, S.C.5
-
118
-
-
7244247277
-
Successive and synergistic action of the Hsp70 and Hsp100 chaperones in protein disaggregation
-
Zietkiewicz S, Krzewska J, Liberek K. 2004. Successive and synergistic action of the Hsp70 and Hsp100 chaperones in protein disaggregation. J. Biol. Chem. 279:44376-83
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 44376-44383
-
-
Zietkiewicz, S.1
Krzewska, J.2
Liberek, K.3
|