Polyubiquitination is required for US11-dependent movement of MHC class I heavy chain from endoplasmic reticulum into cytosol

Molecular Biology of the Cell

Volumn 12, Issue 8, 2001, Pages 2546-2555

  Shamu, C E ^a   Flierman, D ^a   Ploegh, H L ^a   Rapoport, T A ^a   Chau, V ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LYSINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; POLYUBIQUITIN; PROTEASOME; PROTEIN US11; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CELL FRACTIONATION; CELL MEMBRANE TRANSPORT; CONTROLLED STUDY; CYTOMEGALOVIRUS; CYTOSOL; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN LOCALIZATION;

EID: 0035167960     PISSN: 10591524     EISSN: None     Source Type: Journal    
DOI: 10.1091/mbc.12.8.2546     Document Type: Article

References (29)

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5. A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p
6. Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast
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15. Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation
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