The tumor suppressor WARTS activates the Omi/HtrA2-dependent pathway of cell death

Oncogene

Volumn 24, Issue 34, 2005, Pages 5287-5298

  Kuninaka, Shinji ^a   Nomura, Masanobu ^a   Hirota, Toru ^a   Iida, Shin Ichi ^a   Hara, Toshihiro ^a   Honda, Shinobu ^a   Kunitoku, Naoko ^a   Sasayama, Takashi ^a   Arima, Yoshimi ^a   Marumoto, Tomotoshi ^a   Koja, Kageharu ^b   Yonehara, Shin ^c   Saya, Hideyuki ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

Apoptosis; Cancer; Caspases; IAPs; Mitochondria; Mitotic kinases; PDZ domain

Indexed keywords

DROSOPHILA PROTEIN; PDZ PROTEIN; PROTEIN WARTS; PROTEIN WTS; SERINE PROTEINASE OMI; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; LATS1 PROTEIN, HUMAN; MITOCHONDRIAL PROTEIN; PROTEIN SERINE THREONINE KINASE; SERINE PROTEINASE;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FUNCTIONAL PROTEOMICS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPLETION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; CELL CULTURE; CYTOSOL; GENETIC TRANSFECTION; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

INTRACISTERNAL A-PARTICLES;

APOPTOSIS; CELLS, CULTURED; CYTOSOL; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTEIN-SERINE-THREONINE KINASES; SERINE ENDOPEPTIDASES; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 24044468709     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1208682     Document Type: Article

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